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Aliases for PRR30 Gene

Aliases for PRR30 Gene

  • Proline Rich 30 2 3
  • C2orf53 3 4
  • Chromosome 2 Open Reading Frame 53 2

External Ids for PRR30 Gene

Previous HGNC Symbols for PRR30 Gene

  • C2orf53

Summaries for PRR30 Gene

GeneCards Summary for PRR30 Gene

PRR30 (Proline Rich 30) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRR30 Gene

Genomics for PRR30 Gene

Genomic Location for PRR30 Gene

27,136,847 bp from pter
27,139,464 bp from pter
2,618 bases
Minus strand

Genomic View for PRR30 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PRR30 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRR30 Gene

No data available for Regulatory Elements for PRR30 Gene

Proteins for PRR30 Gene

  • Protein details for PRR30 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Proline-rich protein 30
    Protein Accession:
    Secondary Accessions:
    • Q86UE2

    Protein attributes for PRR30 Gene

    412 amino acids
    Molecular mass:
    44690 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PRR30 Gene

Proteomics data for PRR30 Gene at MOPED

Post-translational modifications for PRR30 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PRR30 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for PRR30 Gene

Domains & Families for PRR30 Gene

Protein Domains for PRR30 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PRR30: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PRR30 Gene

Function for PRR30 Gene

Phenotypes for PRR30 Gene

GenomeRNAi human phenotypes for PRR30:
genes like me logo Genes that share phenotypes with PRR30: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for PRR30

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRR30 Gene

Localization for PRR30 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PRR30 Gene

Pathways & Interactions for PRR30 Gene

SuperPathways for PRR30 Gene

No Data Available

Interacting Proteins for PRR30 Gene

Gene Ontology (GO) - Biological Process for PRR30 Gene


No data available for Pathways by source and SIGNOR curated interactions for PRR30 Gene

Drugs & Compounds for PRR30 Gene

No Compound Related Data Available

Transcripts for PRR30 Gene

mRNA/cDNA for PRR30 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for PRR30

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PRR30 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b · 4c
SP1: - -
SP2: - -

Relevant External Links for PRR30 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PRR30 Gene

mRNA expression in normal human tissues for PRR30 Gene

Protein differential expression in normal tissues from HIPED for PRR30 Gene

This gene is overexpressed in Testis (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PRR30 Gene

genes like me logo Genes that share expression patterns with PRR30: view

Protein tissue co-expression partners for PRR30 Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for PRR30 Gene

Orthologs for PRR30 Gene

This gene was present in the common ancestor of mammals.

Orthologs for PRR30 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C11H2orf53 35
  • 79.12 (n)
  • 67.17 (a)
C2orf53 36
  • 66 (a)
(Mus musculus)
Mammalia 1700110M21Rik 35
  • 69.79 (n)
  • 55.44 (a)
1700110M21Rik 16
1700110M21Rik 36
  • 55 (a)
(Pan troglodytes)
Mammalia C2AH2orf53 35
  • 96.75 (n)
  • 94.01 (a)
C2orf53 36
  • 91 (a)
(Rattus norvegicus)
Mammalia LOC100322897 35
  • 73.25 (n)
  • 58.73 (a)
(Ornithorhynchus anatinus)
Mammalia C2orf53 36
  • 29 (a)
Species with no ortholog for PRR30:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PRR30 Gene

Gene Tree for PRR30 (if available)
Gene Tree for PRR30 (if available)

Paralogs for PRR30 Gene

No data available for Paralogs for PRR30 Gene

Variants for PRR30 Gene

Sequence variations from dbSNP and Humsavar for PRR30 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs11121 -- 27,137,019(-) TCTCG(A/G)GGAGT utr-variant-3-prime
rs2304679 -- 27,138,354(+) ACTGG(A/G)GCAAC utr-variant-5-prime
rs2304680 -- 27,138,378(+) AGAGA(C/T)CTGGC utr-variant-5-prime
rs3739097 - 27,137,666(+) GCGGC(A/G)GTGCC reference, missense
rs3795961 -- 27,139,079(+) CCAGC(A/G)TCTAA intron-variant

Variation tolerance for PRR30 Gene

Residual Variation Intolerance Score: 83.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 5.45; 71.47% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PRR30 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for PRR30 Gene

Disorders for PRR30 Gene

Relevant External Links for PRR30

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with PRR30: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRR30 Gene

Publications for PRR30 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 67
  2. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 67
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 67
  4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 67
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for PRR30 Gene

Sources for PRR30 Gene

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