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Aliases for PRR29 Gene

Aliases for PRR29 Gene

  • Proline Rich 29 2 3 5
  • C17orf72 3 4
  • Chromosome 17 Open Reading Frame 72 2
  • Proline-Rich Protein 29 3

External Ids for PRR29 Gene

Previous HGNC Symbols for PRR29 Gene

  • C17orf72

Summaries for PRR29 Gene

GeneCards Summary for PRR29 Gene

PRR29 (Proline Rich 29) is a Protein Coding gene.

Additional gene information for PRR29 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRR29 Gene

Genomics for PRR29 Gene

Regulatory Elements for PRR29 Gene

Enhancers for PRR29 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17H064013 1.7 FANTOM5 ENCODE dbSUPER 33.9 +21.7 21684 12.9 HDGF PKNOX1 FOXA2 MLX ARNT ARID4B SIN3A YBX1 DMAP1 ZNF2 PRR29 SMARCD2 DDX5 FTSJ3 PLEKHM1P1 POLG2 ENSG00000281311 CEP95 DDX42 CSHL1
GH17H064005 1.5 Ensembl ENCODE dbSUPER 37.9 +9.5 9457 5.2 HDGF PKNOX1 ATF1 FOXA2 TCF12 ZNF766 GLIS2 GATA2 ATF7 SP5 PRR29 GH1 CSHL1 GC17M064000 ICAM2
GH17H064001 1.1 Ensembl ENCODE dbSUPER 40.9 +3.8 3781 1.3 NFIL3 POLR2A CEBPA HLF ETV4 CEBPB CEBPG PRR29 GC17P064004 PRR29-AS1 PIR47420
GH17H063997 1.2 ENCODE dbSUPER 16.7 -0.5 -469 1.6 HDAC1 ELF3 NFIB ARID4B SIN3A BMI1 ZBTB40 GLIS2 ELK1 HSF1 PRR29 FTSJ3 POLG2 SLC16A6P1 MAP3K3 SCN4A
GH17H063982 1.4 Ensembl ENCODE dbSUPER 9.6 -13.8 -13758 3.3 PKNOX1 FOXA2 TBL1XR1 ZSCAN4 SIN3A KLF17 BMI1 BATF RAD21 ZBTB7B FTSJ3 POLG2 DDX42 DDX5 CEP95 MAP3K3 CD79B CSHL1 GH1 ICAM2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around PRR29 on UCSC Golden Path with GeneCards custom track

Promoters for PRR29 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000096873 156 601 HDAC1 ELF3 NFIB ARID4B SIN3A BMI1 ZBTB40 GLIS2 ELK1 HSF1

Genomic Locations for PRR29 Gene

Genomic Locations for PRR29 Gene
chr17:63,998,344-64,004,305
(GRCh38/hg38)
Size:
5,962 bases
Orientation:
Plus strand
chr17:62,075,711-62,081,664
(GRCh37/hg19)

Genomic View for PRR29 Gene

Genes around PRR29 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRR29 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRR29 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRR29 Gene

Proteins for PRR29 Gene

  • Protein details for PRR29 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0C7W0-PRR29_HUMAN
    Recommended name:
    Proline-rich protein 29
    Protein Accession:
    P0C7W0
    Secondary Accessions:
    • B3KMP0
    • B4DZJ9
    • B4E2F8
    • E9PGL5
    • J3QKX4

    Protein attributes for PRR29 Gene

    Size:
    189 amino acids
    Molecular mass:
    20715 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for PRR29 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PRR29 Gene

Post-translational modifications for PRR29 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PRR29 Gene

Domains & Families for PRR29 Gene

Gene Families for PRR29 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for PRR29 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for PRR29 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PRR29: view

No data available for UniProtKB/Swiss-Prot for PRR29 Gene

Function for PRR29 Gene

Phenotypes for PRR29 Gene

GenomeRNAi human phenotypes for PRR29:
genes like me logo Genes that share phenotypes with PRR29: view

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRR29 Gene

Localization for PRR29 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PRR29 gene
Compartment Confidence
plasma membrane 2
cytosol 2
extracellular 1
mitochondrion 1
peroxisome 1
nucleus 1

Subcellular locations from the

Human Protein Atlas (HPA)

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for PRR29 Gene

Pathways & Interactions for PRR29 Gene

SuperPathways for PRR29 Gene

No Data Available

Interacting Proteins for PRR29 Gene

Gene Ontology (GO) - Biological Process for PRR29 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PRR29 Gene

Drugs & Compounds for PRR29 Gene

No Compound Related Data Available

Transcripts for PRR29 Gene

mRNA/cDNA for PRR29 Gene

(8) REFSEQ mRNAs :
(10) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for PRR29 Gene

No ASD Table

Relevant External Links for PRR29 Gene

GeneLoc Exon Structure for
PRR29
ECgene alternative splicing isoforms for
PRR29

Expression for PRR29 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for PRR29 Gene

NURSA nuclear receptor signaling pathways regulating expression of PRR29 Gene:

PRR29
genes like me logo Genes that share expression patterns with PRR29: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PRR29 Gene

Orthologs for PRR29 Gene

This gene was present in the common ancestor of chordates.

Orthologs for PRR29 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C17H17orf72 33
  • 99.47 (n)
C17orf72 34
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia C9H17orf72 33
  • 81.24 (n)
C17orf72 34
  • 60 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C19H17orf72 33
  • 75.69 (n)
mouse
(Mus musculus)
Mammalia 2310007L24Rik 33 34
  • 74.23 (n)
Prr29 16
rat
(Rattus norvegicus)
Mammalia RGD1307288 33
  • 72.79 (n)
oppossum
(Monodelphis domestica)
Mammalia C17orf72 34
  • 39 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia C17orf72 34
  • 30 (a)
OneToOne
Species where no ortholog for PRR29 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PRR29 Gene

ENSEMBL:
Gene Tree for PRR29 (if available)
TreeFam:
Gene Tree for PRR29 (if available)

Paralogs for PRR29 Gene

No data available for Paralogs for PRR29 Gene

Variants for PRR29 Gene

Sequence variations from dbSNP and Humsavar for PRR29 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1000648479 -- 63,999,304(+) AGGAG(A/G)TTTCC intron-variant, nc-transcript-variant
rs1000751123 -- 63,999,666(+) GAGAC(A/T)GAATG intron-variant, nc-transcript-variant
rs1000904637 -- 64,004,537(+) AAAAT(A/G)TGTTG intron-variant, downstream-variant-500B
rs1000949632 -- 64,004,251(+) CCTCT(C/T)CTTCA intron-variant, utr-variant-3-prime
rs1001128721 -- 63,999,795(+) CAAGT(A/G)TGTGT intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for PRR29 Gene

Variant ID Type Subtype PubMed ID
nsv952357 CNV deletion 24416366
nsv833511 CNV loss 17160897
nsv517272 CNV gain+loss 19592680

Variation tolerance for PRR29 Gene

Gene Damage Index Score: 9.49; 88.76% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PRR29 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
PRR29

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PRR29 Gene

Disorders for PRR29 Gene

Relevant External Links for PRR29

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PRR29

No disorders were found for PRR29 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRR29 Gene

Publications for PRR29 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 60
  4. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 4 60

Products for PRR29 Gene

Sources for PRR29 Gene

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