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Aliases for PRR27 Gene

Aliases for PRR27 Gene

  • Proline Rich 27 2 3
  • C4orf40 3 4
  • Chromosome 4 Open Reading Frame 40 2

External Ids for PRR27 Gene

Previous HGNC Symbols for PRR27 Gene

  • C4orf40

Previous GeneCards Identifiers for PRR27 Gene

  • GC04P071000

Summaries for PRR27 Gene

GeneCards Summary for PRR27 Gene

PRR27 (Proline Rich 27) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRR27 Gene

Genomics for PRR27 Gene

Genomic Location for PRR27 Gene

70,133,616 bp from pter
70,176,799 bp from pter
43,184 bases
Plus strand

Genomic View for PRR27 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for PRR27 Gene

No data available for Regulatory Elements for PRR27 Gene

Proteins for PRR27 Gene

  • Protein details for PRR27 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Proline-rich protein 27
    Protein Accession:
    Secondary Accessions:
    • A8MXP0
    • Q6MZR6

    Protein attributes for PRR27 Gene

    219 amino acids
    Molecular mass:
    22720 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PRR27 Gene

Proteomics data for PRR27 Gene at MOPED

Post-translational modifications for PRR27 Gene

No Post-translational modifications

Other Protein References for PRR27 Gene

No data available for DME Specific Peptides for PRR27 Gene

Domains & Families for PRR27 Gene

Protein Domains for PRR27 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PRR27: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PRR27 Gene

Function for PRR27 Gene

Phenotypes for PRR27 Gene

GenomeRNAi human phenotypes for PRR27:
genes like me logo Genes that share phenotypes with PRR27: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for PRR27

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRR27 Gene

Localization for PRR27 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PRR27 Gene


Gene Ontology (GO) - Cellular Components for PRR27 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome IDA 19199708
genes like me logo Genes that share ontologies with PRR27: view

No data available for Subcellular locations from COMPARTMENTS for PRR27 Gene

Pathways & Interactions for PRR27 Gene

SuperPathways for PRR27 Gene

No Data Available

Interacting Proteins for PRR27 Gene

Gene Ontology (GO) - Biological Process for PRR27 Gene


No data available for Pathways by source and SIGNOR curated interactions for PRR27 Gene

Drugs & Compounds for PRR27 Gene

No Compound Related Data Available

Transcripts for PRR27 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for PRR27

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PRR27 Gene

No ASD Table

Relevant External Links for PRR27 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PRR27 Gene

mRNA expression in normal human tissues for PRR27 Gene

mRNA differential expression in normal tissues according to GTEx for PRR27 Gene

This gene is overexpressed in Minor Salivary Gland (x44.7) and Testis (x6.5).

Protein differential expression in normal tissues from HIPED for PRR27 Gene

This gene is overexpressed in Skin (38.1) and Salivary gland (25.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PRR27 Gene

genes like me logo Genes that share expression patterns with PRR27: view

Protein tissue co-expression partners for PRR27 Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for PRR27 Gene

Orthologs for PRR27 Gene

This gene was present in the common ancestor of mammals.

Orthologs for PRR27 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia PRR27 35
  • 98.93 (n)
  • 97.26 (a)
C4orf40 36
  • 97 (a)
(Mus musculus)
Mammalia 4930432K09Rik 16
4930432K09Rik 36
  • 28 (a)
(Canis familiaris)
Mammalia C4orf40 36
  • 40 (a)
Species with no ortholog for PRR27:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PRR27 Gene

Gene Tree for PRR27 (if available)
Gene Tree for PRR27 (if available)

Paralogs for PRR27 Gene

No data available for Paralogs for PRR27 Gene

Variants for PRR27 Gene

Sequence variations from dbSNP and Humsavar for PRR27 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type MAF
VAR_043928 -
VAR_043927 -

Variation tolerance for PRR27 Gene

Residual Variation Intolerance Score: 89.87% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.86; 58.92% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PRR27 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for PRR27 Gene

Disorders for PRR27 Gene

Relevant External Links for PRR27

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with PRR27: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRR27 Gene

Publications for PRR27 Gene

  1. Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). (PMID: 19199708) Gonzalez-Begne M. … Yates J.R. (J. Proteome Res. 2009) 67
  2. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 67
  3. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A. … Wiemann S. (Nucleic Acids Res. 2006) 67
  4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 67
  5. From ORFeome to biology: a functional genomics pipeline. (PMID: 15489336) Wiemann S. … Poustka A. (Genome Res. 2004) 67

Products for PRR27 Gene

Sources for PRR27 Gene

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