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Aliases for PRR26 Gene

Subcategory (RNA class) for PRR26 Gene


Quality Score for this RNA gene is


Aliases for PRR26 Gene

  • Proline Rich 26 2 3 5
  • C10orf108 3 4
  • Chromosome 10 Open Reading Frame 108 2

External Ids for PRR26 Gene

Previous HGNC Symbols for PRR26 Gene

  • C10orf108

Previous GeneCards Identifiers for PRR26 Gene

  • GC10P000696

Summaries for PRR26 Gene

GeneCards Summary for PRR26 Gene

PRR26 (Proline Rich 26) is an RNA Gene, and is affiliated with the ncRNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRR26 Gene

Genomics for PRR26 Gene

Regulatory Elements for PRR26 Gene

Enhancers for PRR26 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH10G000623 1.5 Ensembl ENCODE dbSUPER 12 -24.7 -24690 3.0 HDGF PKNOX1 ATF1 FEZF1 ZNF2 GLIS2 FOS ZNF263 TSHZ1 ZNF488 PRR26 DIP2C LOC101930421 PIR41309
GH10G000612 1.3 Ensembl ENCODE dbSUPER 12 -35.4 -35377 4.3 HDGF NFIB ZSCAN4 SIN3A RAD21 FOS RCOR1 ZHX2 GATAD2B ZNF592 PRR26 DIP2C TUBB8 LOC101930421 PIR32536
GH10G000609 1.3 Ensembl ENCODE dbSUPER 12 -39.3 -39267 2.6 KLF1 KLF17 ZIC2 ZFHX2 GLIS2 EGR1 SCRT2 ZSCAN5C FOS ZNF600 PRR26 DIP2C LOC101930421 PIR32536
GH10G000597 1.2 Ensembl ENCODE dbSUPER 12.4 -50.9 -50867 4.1 BCOR RAD21 YY1 ZFHX2 GATA2 FOS EGR2 ZNF263 BHLHE40 REST LOC101930421 PRR26 DIP2C TUBB8 PIR32536
GH10G000593 1.1 Ensembl ENCODE dbSUPER 11.2 -55.8 -55789 1.3 ZNF133 BHLHE40 YY1 ZBTB48 FOS ZNF24 NFE2 HNF4A NFE2L2 PRR26 DIP2C PIR32536 LOC101930421
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around PRR26 on UCSC Golden Path with GeneCards custom track

Genomic Location for PRR26 Gene

649,948 bp from pter
669,581 bp from pter
19,634 bases
Plus strand

Genomic View for PRR26 Gene

Genes around PRR26 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRR26 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRR26 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRR26 Gene

Proteins for PRR26 Gene

  • Protein details for PRR26 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Proline-rich protein 26
    Protein Accession:

    Protein attributes for PRR26 Gene

    221 amino acids
    Molecular mass:
    24207 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PRR26 Gene

Post-translational modifications for PRR26 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PRR26 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for PRR26 Gene

Domains & Families for PRR26 Gene

Protein Domains for PRR26 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PRR26: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PRR26 Gene

Function for PRR26 Gene

Phenotypes for PRR26 Gene

GenomeRNAi human phenotypes for PRR26:
genes like me logo Genes that share phenotypes with PRR26: view

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PRR26 Gene

Localization for PRR26 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PRR26 gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for PRR26 Gene

Pathways & Interactions for PRR26 Gene

SuperPathways for PRR26 Gene

No Data Available

Interacting Proteins for PRR26 Gene

Gene Ontology (GO) - Biological Process for PRR26 Gene


No data available for Pathways by source and SIGNOR curated interactions for PRR26 Gene

Drugs & Compounds for PRR26 Gene

No Compound Related Data Available

Transcripts for PRR26 Gene

mRNA/cDNA for PRR26 Gene

(1) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for PRR26 Gene

Proline rich 26:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for PRR26 Gene

No ASD Table

Relevant External Links for PRR26 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PRR26 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for PRR26 Gene

mRNA differential expression in normal tissues according to GTEx for PRR26 Gene

This gene is overexpressed in Colon - Sigmoid (x5.6).

Protein differential expression in normal tissues from HIPED for PRR26 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PRR26 Gene

Protein tissue co-expression partners for PRR26 Gene

NURSA nuclear receptor signaling pathways regulating expression of PRR26 Gene:


SOURCE GeneReport for Unigene cluster for PRR26 Gene:

genes like me logo Genes that share expression patterns with PRR26: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PRR26 Gene

Orthologs for PRR26 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for PRR26 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia PRR26 35
  • 98 (a)
Species where no ortholog for PRR26 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PRR26 Gene

Gene Tree for PRR26 (if available)
Gene Tree for PRR26 (if available)

Paralogs for PRR26 Gene

No data available for Paralogs for PRR26 Gene

Variants for PRR26 Gene

Sequence variations from dbSNP and Humsavar for PRR26 Gene

SNP ID Clin Chr 10 pos Sequence Context AA Info Type
rs1000070042 -- 665,488(+) CTTCA(C/T)ATAAG intron-variant, upstream-variant-2KB
rs1000483326 -- 662,929(+) TGTAC(A/G)CTAAT intron-variant, nc-transcript-variant
rs1000717633 -- 656,751(+) AAGAC(A/G)GACGG intron-variant
rs1000912599 -- 656,311(+) CTTCT(A/G)CTCTA intron-variant
rs1000913239 -- 648,336(+) CCACA(C/T)TGGAT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for PRR26 Gene

Variant ID Type Subtype PubMed ID
dgv118n67 CNV gain 20364138
dgv340e59 CNV duplication 20981092
dgv651n100 CNV gain 25217958
esv1255045 CNV deletion 17803354
esv21741 CNV gain 19812545
esv2537541 CNV insertion 19546169
esv2660097 CNV deletion 23128226
esv2728618 CNV deletion 23290073
esv2728629 CNV deletion 23290073
nsv1069437 CNV deletion 25765185
nsv1120210 CNV tandem duplication 24896259
nsv1140441 CNV tandem duplication 24896259
nsv1146678 CNV insertion 26484159
nsv24219 CNV deletion 16902084
nsv528733 CNV gain 19592680
nsv549751 CNV gain 21841781
nsv549753 CNV gain 21841781
nsv549764 CNV loss 21841781

Variation tolerance for PRR26 Gene

Gene Damage Index Score: 1.69; 32.16% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PRR26 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PRR26 Gene

Disorders for PRR26 Gene

Relevant External Links for PRR26

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for PRR26 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRR26 Gene

Publications for PRR26 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. The DNA sequence and comparative analysis of human chromosome 10. (PMID: 15164054) Deloukas P. … Rogers J. (Nature 2004) 3 4 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for PRR26 Gene

Sources for PRR26 Gene

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