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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PRPS1L1 Gene

protein-coding   GIFtS: 54
GCID: GC07M018066

phosphoribosyl pyrophosphate synthetase 1-like 1


(Previous symbol: PRPSL)
 Explore 10 diseases affiliated with
PRPS1L1 via our new
 Human Malady Compendium 
Biological research products
for PRPS1L1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Phosphoribosyl Pyrophosphate Synthetase 1-Like 11 2     EC 2.7.6.13 8
PRPS31 2 3 5     PRPS12
PRPSL1 2 3     Phosphoribosylpyrophosphate Synthetase Subunit III2
Phosphoribosyl Pyrophosphate Synthase 1-Like 12 3     Ribose-Phosphate Diphosphokinase Catalytic Chain III2
Phosphoribosyl Pyrophosphate Synthase III2 3     Ribose-Phosphate Pyrophosphokinase 32
PRS-III2 3     Ribose-Phosphate Pyrophosphokinase III2
PRPS1-Like 12 3     

External Ids:    HGNC: 94631   Entrez Gene: 2218232   Ensembl: ENSG000002299377   OMIM: 6115665   UniProtKB: P211083   

Export aliases for PRPS1L1 gene to outside databases

Previous GC identifers: GC07U990077 GC07M017810 GC07M017839 GC07M018032


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PRPS1L1:
This intronless gene is specifically expressed in the testis, and encodes a protein that is highly homologous to the
two subunits of phosphoribosylpyrophosphate synthetase encoded by human X-linked genes, PRPS1 and PRPS2. These enzymes
convert pyrimidine, purine or pyridine bases to the corresponding ribonucleoside monophosphates. In vitro
transcription/translation and site-directed mutagenesis studies indicate that translation of this mRNA initiates
exclusively at a non-AUG (ACG) codon. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: PRPS3_HUMAN, P21108
Function: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.1  NT_007819.17  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PRPS1L1 gene promoter:
         Brachyury   ATF-2   CUTL1   STAT5A   HNF-3beta   Cdc5   POU2F1   POU2F1a   c-Myb   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPRPS1L1 promoter sequence
   Search SABiosciences Chromatin IP Primers for PRPS1L1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PRPS1L1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p21.1   Ensembl cytogenetic band:  7p21.1   HGNC cytogenetic band: 7p21.1

PRPS1L1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PRPS1L1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M018066:  view genomic region     (about GC identifiers)

Start:
18,066,397 bp from pter      End:
18,067,486 bp from pter
Size:
1,090 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 18,119,717-18,120,801     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: PRPS3_HUMAN, P21108 (See protein sequence)
Recommended Name: Ribose-phosphate pyrophosphokinase 3  
Size: 318 amino acids; 34839 Da
Cofactor: Magnesium
Subunit: Homodimer. The active form is probably a hexamer composed of 3 homodimers (By similarity)
Caution: According to PubMed:2168892, this sequence initiates from a non-AUG codon; N-terminal ACG codon did serve as a
start codon
Secondary accessions: Q6P5P6

Explore the universe of human proteins at neXtProt for PRPS1L1: NX_P21108

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P21108

  • 4/22 DME Specific Peptides for PRPS1L1 (P21108) (see all 22)
     GLELGKV  QIQGFFD  KLVANML  LMELLIM 

    PRPS1L1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_787082.1  
    ENSEMBL proteins: 
     ENSP00000424595  
    Reactome Protein details: P21108
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    Uscn Proteins for PRPS1L1

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--


    PRPS1L1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    PRPS1L1 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR000842 PRib_PP_synth_CS
     IPR005946 Rib-P_diPkinase
     IPR000836 PRibTrfase_dom

    Graphical View of Domain Structure for InterPro Entry P21108

    ProtoNet protein and cluster: P21108

    1 Blocks protein family: IPB000842 Phosphoribosyl pyrophosphate synthetase

    UniProtKB/Swiss-Prot: PRPS3_HUMAN, P21108
    Similarity: Belongs to the ribose-phosphate pyrophosphokinase family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: PRPS3_HUMAN, P21108
    Function: Catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis
    Catalytic activity: ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate
    Enzyme regulation: Activated by magnesium and inorganic phosphate

         Genatlas biochemistry entry for PRPS1L1:
    phosphoribosyl pyrophosphate synthetase 1-like 1

    Enzyme Number (IUBMB): EC 2.7.6.11 2

    miRNA
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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000287magnesium ion binding IEA--
    GO:0004749ribose phosphate diphosphokinase activity NAS2168892
    GO:0005524ATP binding ISS--
    GO:0016301kinase activity IEA--
    GO:0042803protein homodimerization activity ISS--


    PRPS1L1 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for PRPS1L1:
     Increased viability after born  Paclitaxel antagonistic effect 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    15-Phosphoribose 1-diphosphate biosynthesis
    5-Phosphoribose 1-diphosphate biosynthesis1.00
    PRPP biosynthesis I0.67
    2Metabolism
    Metabolism1.00
    Metabolic pathways0.38
    3Purine metabolism
    Purine metabolism1.00
    4Pentose phosphate pathway
    Pentose phosphate pathway1.00
    5MPS IIIC - Sanfilippo syndrome C
    Metabolism of carbohydrates0.47

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 BioSystems Pathway for PRPS1L1 
        PRPP biosynthesis I

    3        Reactome Pathways for PRPS1L1
        5-Phosphoribose 1-diphosphate biosynthesis
    Metabolism of carbohydrates
    Metabolism


    3         Kegg Pathways  (Kegg details for PRPS1L1):
        Pentose phosphate pathway
    Purine metabolism
    Metabolic pathways

    UniProtKB/Swiss-Prot: PRPS3_HUMAN, P21108
    Pathway: Metabolic intermediate biosynthesis; 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis;
    5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route I): step 1/1


    PRPS1L1 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PRPS1L1

    5/12 Interacting proteins for PRPS1L1 (P211083) via UniProtKB, MINT, STRING, and/or I2D (see all 12)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    C12orf44Q9BSB43I2D: score=1 
    DDA1Q9BW613I2D: score=1 
    GBASO753233I2D: score=1 
    PIK3C2AO004433I2D: score=1 
    PRKAG1P546193I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:00060155-phosphoribose 1-diphosphate biosynthetic process IEA--
    GO:0009116nucleoside metabolic process IEA--
    GO:0009156ribonucleoside monophosphate biosynthetic process NAS--
    GO:0009165nucleotide biosynthetic process IEA--


    PRPS1L1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    PRPS1L1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for PRPS1L1

    6 HMDB Compounds for PRPS1L1    About this table
    CompoundSynonyms CAS #PubMed Ids
    Adenosine monophosphate5'-AMP (see all 28)61-19-8--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    D-Ribose 5-phosphateD-Ribose 5-phosphate (see all 11)3615-55-2--
    D-Ribulose 5-phosphateD-Ribulose 5-phosphate (see all 5)4151-19-3--
    MagnesiumMagnesium (see all 2)7439-95-4--
    Phosphoribosyl pyrophosphate5-Phospho-a-D-ribose-1-diphosphate (see all 37)7540-64-9--
    1 Novoseek chemical compound relationship for PRPS1L1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    prpp 92.2 6 17701900 (2), 1962753 (2), 2168892 (1), 1314091 (1)

    Search CenterWatch for drugs/clinical trials and news about PRPS1L1 / PRPS3 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PRPS1L1 gene: 
    NM_175886.2  

    Unigene Cluster for PRPS1L1:

    Phosphoribosyl pyrophosphate synthetase 1-like 1
    Hs.169284  [show with all ESTs]
    Unigene Representative Sequence: NM_175886
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000506618(uc003stz.3)

    miRNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PRPS1L1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PRPS1L1

    Additional cDNA sequence: 

    BC005309.1 BC062797.1 M57423.1 

    1 DOTS entry:

    DT.40119884 

    10 AceView cDNA sequences:

    BI830385 M57423 NM_175886 BX281962 BC005309 BI561282 BC062797 BQ428750 
    AW072461 BP368905 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PRPS1L1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTCCTTTATA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See PRPS1L1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PRPS1L1

    SOURCE GeneReport for Unigene cluster: Hs.169284

    UniProtKB/Swiss-Prot: PRPS3_HUMAN, P21108
    Tissue specificity: Testis

        SABiosciences Expression via Pathway-Focused PCR Array including PRPS1L1: 
              Glucose Metabolism in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for PRPS1L1 gene from 7/29 species (see all 29)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves F1NIP5_CHICK6
    Ribose-phosphate pyrophosphokinase
    91(a)
    1 → many
    4(1948779-1957667)
    zebrafish
    (Danio rerio)
    Actinopterygii prps1b6
    prps1a6
    phosphoribosyl pyrophosphate synthetase 1A
    93(a)
    91(a)
    possible ortholog
    1 ↔ many
    14(12335034-12364816)
    5(24805479-24816595)
    fruit fly
    (Drosophila melanogaster)
    Insecta CG67676
    --
    70(a)
    1 → many
    3L(9676679-9689800)
    worm
    (Caenorhabditis elegans)
    Secernentea R151.26
    Ribose-phosphate pyrophosphokinase
    56(a)
    1 → many
    III(7209905-7215049)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G445306
    AT2G353906
    (see all 5)
    ribose-phosphate pyrophosphokinase 1
    (see all 5)
    35(a)
    35(a)
    (see all 5)
    possible ortholog
    possible ortholog
    (see all 5)
    2(18383515-18386143)
    2(14895279-14897822)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 6)
    phosphoribosyl transferase, putative, expressed
    (see all 6)
    36(a)
    35(a)
    (see all 6)
    possible ortholog
    possible ortholog
    (see all 6)
    2(1437433-1441125)
    3(18106-19491)
    E. coli
    (Escherichia coli)
    Gamma proteobacteria prs6
    phosphoribosylpyrophosphate synthase
    46(a)
    possible ortholog
    Chromosome(1260151-1261098)


    ENSEMBL Gene Tree for PRPS1L1 (if available)
    TreeFam Gene Tree for PRPS1L1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PRPS1L1 gene
    PRPSAP12  PRPS12  PRPS22  PRPSAP22  
    4 SIMAP similar genes for PRPS1L1 using alignment to 1 protein entry:     PRPS3_HUMAN:
    PRPS1    PRPS2    PRPSAP2    PRPSAP1

    PRPS1L1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/80 NCBI SNPs in PRPS1L1 are shown (see all 80    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1143420191,2
    --18065902(+) TCCCAA/GTGGCT 1 -- int11Minor allele frequency- G:0.01WA 118
    rs1503096151,2
    --18066034(+) GTGGGG/TGTTTG 1 -- int10--------
    rs1380828671,2
    --18066136(+) AAACAC/GCTCTA 1 -- int10--------
    rs1164123571,2
    --18066194(+) TTAAAG/ACTGCT 1 -- int11Minor allele frequency- A:0.01WA 118
    rs1843461231,2
    --18066198(+) AGCTGC/TTGGGC 1 -- int10--------
    rs1491151391,2
    --18066261(+) TGATTA/GTTCTT 1 -- int10--------
    rs1158475131,2
    F,--18066343(+) AAGCTG/AGATCT 1 -- int11Minor allele frequency- A:0.03WA 118
    rs69783391,2
    C,H--18066375(+) CCTAAG/AAAAAA 1 -- int14Minor allele frequency- A:0.00NS EA 388
    rs1887395221,2
    C,--18066419(+) TTATTG/TTAAAA 1 -- ut310--------
    rs1812131511,2
    C,--18066492(+) CCCCAC/TTATGA 2 N S mis10--------

    HapMap Linkage Disequilibrium report for PRPS1L1 (18066397 - 18067486 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for PRPS1L1: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    PRPS1L1 for disorders           About GeneDecksing

    OMIM gene information: 611566    OMIM disorders: --

    10 diseases for PRPS1L1:    About MalaCards
    lesch-nyhan syndrome    saethre-chotzen syndrome    peripheral neuropathy    hearing loss
    brachydactyly    neuropathy    pneumonia    tuberculosis
    malaria    mycobacterium tuberculosis

    2 diseases from the University of Copenhagen DISEASES database for PRPS1L1:
    Hyperuricemia     Lesch-Nyhan syndrome

    Export disorders for PRPS1L1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PRPS1L1 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with PRPS1L1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A human testis-specific mRNA for phosphoribosylpyrophosphate synthetase that initiates from a non-AUG codon. (PubMed id 2168892)1, 2, 3, 9 Taira M.... Tatibana M. (1990)
    2. Promoter regions of the human X-linked housekeeping genes PRPS1 and PRPS2 encoding phosphoribosylpyrophosphate synthetase subunit I and II isoforms. (PubMed id 1314091)1, 9 Ishizuka T.... Tatibana M. (1992)
    3. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    4. Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)1 Emanuele M.J....Elledge S.J. (2011)
    5. Novel autosomal recessive nonsyndromic hearing impair ment locus DFNB90 maps to 7p22.1-p15.3. (PubMed id 21734401)1 Ali G....Leal S.M. (2011)
    6. The protein network surrounding the human telomere re peat binding factors TRF1, TRF2, and POT1. (PubMed id 20811636)1 Giannone R.J....Liu Y. (2010)
    7. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. The sequence of the human genome. (PubMed id 11181995)1 Venter J.C.... Zhu X. (2001)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 221823 HGNC: 9463 AceView: PRPS1L1 Ensembl:ENSG00000229937 euGenes: HUgn221823
    ECgene: PRPS1L1 Kegg: 221823 H-InvDB: PRPS1L1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PRPS1L1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PRPS1L1 gene:
    Search GeneIP for patents involving PRPS1L1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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