PROZ Gene
protein-coding GIFtS: 59
GCID: GC13P113812
|
|
protein Z, vitamin K-dependent plasma glycoprotein
| |
Aliases
for PROZ gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Protein Z, Vitamin K-Dependent Plasma Glycoprotein1 2 | | PZ1 2 | | Vitamin K-Dependent Protein Z2 |
Export aliases for PROZ gene to outside databasesPrevious GC identifers: GC13P112422 GC13P108450 GC13P112899 GC13P111760 GC13P112860 GC13P094251 |
Summaries
for PROZ gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PROZ:
This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into theplasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependentprotease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this proteinare associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are thecause of protein Z deficiency. Alternate splicing results in multiple transcript variants. (provided by RefSeq, Jan2012)
UniProtKB/Swiss-Prot: PROZ_HUMAN, P22891Function: Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles.Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids
|
Genomic Views
for PROZ gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000013.10 NC_018924.1 NT_027140.6
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PROZ gene promoter:
Sp1
Other transcription factors
Search SABiosciences Chromatin IP Primers for PROZ
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PROZ |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 13q34 Ensembl cytogenetic band: 13q34 HGNC cytogenetic band: 13q34PROZ Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13P113812: view genomic region
(about GC identifiers)
Start:
|
113,812,968 bp from pter |
End:
|
113,826,694 bp from pter |
Size:
|
13,727 bases |
Orientation:
|
plus strand |
|
Proteins
for PROZ gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PROZ_HUMAN, P22891 (See
protein sequence)Recommended Name: Vitamin K-dependent protein Z precursor Size: 400 amino acids; 44744 Da
Subunit: Interacts with SERPINA10
Subcellular location: Secreted
Caution: Although related to peptidase S1 family vitamin K-dependent clotting factors, it has lost two of the essentialcatalytic residues and therefore lacks protease activity
2 PDB 3D structures from  and Proteopedia  for PROZ:3F1S (3D)
3H5C (3D)
Secondary accessions: A6NMB4 Q15213 Q5JVF5 Q5JVF6Alternative splicing: 2 isoforms: P22891-1 P22891-2 Explore the universe of human proteins at neXtProt for PROZ: NX_P22891
Post-translational modifications:
The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGFdomains (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P22891
PROZ Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001243063.1 NP_003882.1
ENSEMBL proteins: ENSP00000364697 ENSP00000344458 Reactome Protein details: P22891
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
PROZ for ontologies About GeneDecksing
PROZ Antibody Products:
Assay Products for PROZ: |
Protein
Domains /
Families
for PROZ gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PROZ for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry P22891ProtoNet protein and cluster: P22891 5/6 Blocks protein families (see all 6): IPB000294 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain IPB001254 Serine protease IPB001314 Chymotrypsin serine protease family (S1) signature IPB001438 Type II EGF-like signature IPB002383 Coagulation factor GLA domain signature
UniProtKB/Swiss-Prot: PROZ_HUMAN, P22891Similarity: Belongs to the peptidase S1 familySimilarity: Contains 2 EGF-like domainsSimilarity: Contains 1 Gla (gamma-carboxy-glutamate) domainSimilarity: Contains 1 peptidase S1 domain |
Function
for PROZ gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PROZ_HUMAN, P22891Function: Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles.Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids Genatlas biochemistry entry for PROZ:plasma glycoprotein Z,62kDa,vitamin K-dependent glycoprotein,with two alternatively spliced isoforms,binding tothrombin and promoting its association with phospholipid vesicles
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PROZ (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PROZ
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: PROZ (NM_003891) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PROZ | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PROZ |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PROZ |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004252 | serine-type endopeptidase activity |
IEA | -- | | GO:0005509 | calcium ion binding |
IEA | -- |
PROZ for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Proztm1Gjb for PROZ
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Proz):
PROZ for phenotypes About GeneDecksing
|
Pathways & Interactions
for PROZ gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Gamma-carboxylation, transport, and amino-terminal cleavage of proteins | | | 2 | Asparagine N-linked glycosylation | | | 3 | PTM: gamma carboxylation, hypusine formation and arylsulfatase activation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/7 
Reactome Pathways for PROZ (see all 7)
1  PharmGKB Pathway for PROZ
PROZ for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PROZ
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
4 Interacting proteins for PROZ (P228913 ENSP000003646974) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006508 | proteolysis |
TAS | -- | | GO:0007596 | blood coagulation |
IEA | -- | | GO:0017187 | peptidyl-glutamic acid carboxylation |
TAS | -- | | GO:0043687 | post-translational protein modification |
TAS | -- | | GO:0044267 | cellular protein metabolic process |
TAS | -- |
PROZ for ontologies About GeneDecksing
|
Drugs & Compounds
for PROZ gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for PROZ
1 HMDB Compound for PROZ About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| Menadione | Vitamin K3: 1,4-Dihydro-1,4-dioxo-2-methylnaphthalene (see all 49) | 58-27-5 | -- |
1 DrugBank Compound for PROZ About this table
Search CenterWatch for drugs/clinical trials and news about PROZ
|
Transcripts
for PROZ gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PROZ gene (2 alternative transcripts): NM_001256134.1 NM_003891.2 Unigene Cluster for PROZ: Protein Z, vitamin K-dependent plasma glycoprotein Hs.1011 [show with all ESTs]Unigene Representative Sequence: NM_0012561344 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000375547(uc001vta.1) ENST00000342783(uc010agr.1) ENST00000493630
ENST00000497607
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PROZ (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PROZ
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: PROZ (NM_003891) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PROZ | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PROZ |
Additional cDNA sequence: AY927601.1 BC074906.2 BC074907.2 M55670.1 M55671.1 M59303.1 5 DOTS entries: DT.92025947 DT.100746624 DT.95156448 DT.100722879 DT.40130758 24/28 AceView cDNA sequences (see all 28): CB162081 M59303 AW016352 AI767499 AI492996 M55671 BC074906 BC074907 NM_003891 M55670 AI478550 BX115777 AW016361 AW469680 AW235106 CB148254 AA680349 CB164334 R85275 AA777559 W87606 W87897 AI522084 H74064
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for PROZ About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13a | · | 13b |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | | | - | | - | | | | | | | | | | | | | | |
| SP2: | | | - | | | | | | | | - | | | | | | | | - | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | | | | | | |
ECgene alternative splicing isoforms for PROZ
|
Expression
for PROZ gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PROZ expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGATACGTTA
About this image
See PROZ Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PROZ
SOURCE GeneReport for Unigene cluster: Hs.1011
UniProtKB/Swiss-Prot: PROZ_HUMAN, P22891Tissue specificity: Plasma
SABiosciences Custom PCR Arrays for PROZ
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PROZ
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PROZ | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PROZ | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PROZ | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PROZ |
Orthologs
for PROZ gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for PROZ gene from 3/10 species (see all 10) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
PROZ1 |
protein Z, vitamin K-dependent plasma glycoprotein |
56.79(n)
48.86(a) |
|
418746 XM_416945.3 XP_416945.3 |
lizard
(Anolis carolinensis) |
Reptilia |
PROZ6 |
-- |
45(a) |
1 ↔ 1 |
3(105981310-105988812) |
zebrafish
(Danio rerio) |
Actinopterygii |
FP017167.16proza6 |
--protein Z, vitamin K-dependent plasma glycoprotein... |
33(a)31(a) |
1 ↔ many1 ↔ many |
1(40294-47999) 3(63044926-63055718) |
ENSEMBL Gene Tree for PROZ (if available)
TreeFam Gene Tree for PROZ (if available) |
Paralogs
for PROZ gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PROZ gene
- PAMR12 C1S2 C1R2 C1RL2 F92 MASP12 F102 F22
- HPR2 HP2 PROC2 F72 MASP22
6 SIMAP similar genes for PROZ using alignment to 2 protein entries: PROZ_HUMAN (see all proteins):PRRG3 PROS1 PROC1 F2 F9 PROC
PROZ for paralogs About GeneDecksing
|
Genomic Variants
for PROZ gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 13 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PROZ (113812968 - 113826694 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for PROZ
1 CNV: 71807
1 Indel: 25169
Human Gene Mutation Database (HGMD): PROZ
| SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for PROZ gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PROZ for disorders About GeneDecksing
OMIM gene information: 176895
OMIM disorders: --
20  diseases for PROZ: About MalaCardsvitamin k-dependent clotting factors hiatus hernia warfarin sensitivity gastroesophageal reflux disease
hernia achalasia myocardial infarction thrombophilia
pyelonephritis behcet's disease kidney disease thrombosis
breast cancer ischemia cerebritis retinitis
venous thrombosis venous thromboembolism thromboembolism sepsis
1 Novoseek disease relationship for PROZ gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| stroke |
25.1 |
5 |
14671240 (2), 16155788 (1) |
Genatlas disease: PROZ bleeding tendency,PROZ deficiency
Genetic Association Database (GAD): PROZ
Human Genome Epidemiology (HuGE) Navigator: PROZ (20 documents)
Export disorders for PROZ gene to outside databases
|
Publications
for PROZ gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PROZ gene, integrated from 9 sources (see all 78):
(articles sorted by number of sources associating them with PROZ) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Primary structure of vitamin K-dependent human protein Z. (PubMed id 2403355)1, 2, 3, 9 Sejima H....Suzuki K. (1990)
- Amino acid sequence of human protein Z, a vitamin K-dependent plasma glycoprotein. (PubMed id 2244898)1, 2, 3 Ichinose A.... Davie E.W. (1990)
- A common polymorphism of the protein Z gene is associated with protein Z plasma levels and with risk of cerebral ischemia in the young. (PubMed id 14671240)1, 4, 9 Lichy C....Grau A. (2004)
- Risk of cerebral venous thrombosis and novel gene polymorphisms of the coagulation and fibrinolytic systems. (PubMed id 16155788)1, 4, 9 Lichy C....Grau A. (2006)
- Basis for the specificity and activation of the serpi n protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-as sociated factor Xa. (PubMed id 20427285)1, 2 Huang X....Gettins P.G. (2010)
- Protein Z gene polymorphisms, protein Z concentrations, and ischemic stroke. (PubMed id 15879328)1, 4 Staton J....Eikelboom J.W. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The gene for human protein Z is localized to chromosome 13 at band q34 and is coded by eight regular exons and one alternative exon. (PubMed id 9578570)1, 2 Fujimaki K.... Ichinose A. (1998)
- A new trisaccharide sugar chain linked to a serine residue in the first EGF-like domain of clotting factors VII and IX and protein Z. (PubMed id 2129367)1, 2 Iwanaga S.... Ikenaka T. (1990)
- Identification of a disaccharide (Xyl-Glc) and a trisaccharide (Xyl2- Glc) O-glycosidically linked to a serine residue in the first epidermal growth factor-like domain of human factors VII and IX and protein Z and bovine protein Z. (PubMed id 2511201)1, 2 Nishimura H.... Iwanaga S. (1989)
|
External Searches for PROZ gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PROZ gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PROZ gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PROZ gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PROZ | Pharmacogenomics, SNPs, Pathways | | SeattleSNPs | http://pga.gs.washington.edu/data/proz/ |
|
| | |
About This Section
| Patent Information for PROZ gene:
Search GeneIP for patents involving PROZ
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PROZ gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for PROZ | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PROZ | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PROZ | | | OriGene Protein Over-expression Lysate for PROZ | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PROZ | | OriGene 3'-UTR Clone for PROZ | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PROZ | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PROZ | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PROZ | | OriGene Custom Protein Services for PROZ | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PROZ | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PROZ | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PROZ | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PROZ | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PROZ | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PROZ |
| |
 |  |  |  | |
| | | | Search Tocris compounds for PROZ |
| |  |  |  |  | | | | |
 |
 |
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 | | | PROZ Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PROZ |
|  |  |  | | | | ThermoFisher Antibodies for PROZ |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PROZ |
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