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Aliases for PROSER3 Gene

Aliases for PROSER3 Gene

  • Proline And Serine Rich 3 2 3 5
  • C19orf55 3 4
  • Chromosome 19 Open Reading Frame 55 2
  • Proline And Serine-Rich Protein 3 3

External Ids for PROSER3 Gene

Previous HGNC Symbols for PROSER3 Gene

  • C19orf55

Previous GeneCards Identifiers for PROSER3 Gene

  • GC19P035807
  • GC19P035833
  • GC19P035991

Summaries for PROSER3 Gene

GeneCards Summary for PROSER3 Gene

PROSER3 (Proline And Serine Rich 3) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PROSER3 Gene

Genomics for PROSER3 Gene

Regulatory Elements for PROSER3 Gene

Enhancers for PROSER3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around PROSER3 on UCSC Golden Path with GeneCards custom track

Promoters for PROSER3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for PROSER3 Gene

35,758,143 bp from pter
35,771,028 bp from pter
12,886 bases
Plus strand

Genomic View for PROSER3 Gene

Genes around PROSER3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PROSER3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PROSER3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PROSER3 Gene

Proteins for PROSER3 Gene

  • Protein details for PROSER3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Proline and serine-rich protein 3
    Protein Accession:
    Secondary Accessions:
    • Q8NDI3
    • Q8WWC8
    • Q96NL4

    Protein attributes for PROSER3 Gene

    480 amino acids
    Molecular mass:
    51075 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH17947.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for PROSER3 Gene


neXtProt entry for PROSER3 Gene

Post-translational modifications for PROSER3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for PROSER3 Gene

Domains & Families for PROSER3 Gene

Protein Domains for PROSER3 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PROSER3: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PROSER3 Gene

Function for PROSER3 Gene

Phenotypes for PROSER3 Gene

GenomeRNAi human phenotypes for PROSER3:
genes like me logo Genes that share phenotypes with PROSER3: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PROSER3 Gene

Localization for PROSER3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PROSER3 Gene

Pathways & Interactions for PROSER3 Gene

SuperPathways for PROSER3 Gene

No Data Available

Interacting Proteins for PROSER3 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000380116 Q2NL68-PRSR3_HUMAN for PROSER3 Gene via STRING IID

Gene Ontology (GO) - Biological Process for PROSER3 Gene


No data available for Pathways by source and SIGNOR curated interactions for PROSER3 Gene

Drugs & Compounds for PROSER3 Gene

No Compound Related Data Available

Transcripts for PROSER3 Gene

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PROSER3 Gene

ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b · 3c ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12
SP1: - - -
SP2: - -
SP3: - -
SP4: -
SP5: -

Relevant External Links for PROSER3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PROSER3 Gene

mRNA expression in normal human tissues for PROSER3 Gene

Protein differential expression in normal tissues from HIPED for PROSER3 Gene

This gene is overexpressed in Liver (63.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for PROSER3 Gene

Protein tissue co-expression partners for PROSER3 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of PROSER3 Gene:

genes like me logo Genes that share expression patterns with PROSER3: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for PROSER3 Gene

Orthologs for PROSER3 Gene

This gene was present in the common ancestor of chordates.

Orthologs for PROSER3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C18H19orf55 34
  • 78.73 (n)
  • 69.52 (a)
C19orf55 35
  • 38 (a)
(Canis familiaris)
Mammalia C1H19orf55 34
  • 83.46 (n)
  • 78.88 (a)
C19orf55 35
  • 46 (a)
(Mus musculus)
Mammalia BC053749 35
  • 34 (a)
(Pan troglodytes)
Mammalia C19orf55 35
  • 83 (a)
(Anolis carolinensis)
Reptilia C19orf55 35
  • 31 (a)
(Danio rerio)
Actinopterygii C15H19orf55 35
  • 17 (a)
Species where no ortholog for PROSER3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for PROSER3 Gene

Gene Tree for PROSER3 (if available)
Gene Tree for PROSER3 (if available)

Paralogs for PROSER3 Gene

No data available for Paralogs for PROSER3 Gene

Variants for PROSER3 Gene

Sequence variations from dbSNP and Humsavar for PROSER3 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs231219 - 35,766,904(-) CCCTT(C/G)CTTCC reference, missense, utr-variant-3-prime
rs231217 - 35,767,941(-) GAGGC(C/G)TTGAC reference, missense
rs3043403 -- 35,762,546(-) ttttt(-/T/TT)agtag intron-variant
rs10439090 -- 35,763,635(+) agtag(C/G)tggga intron-variant
rs11084829 -- 35,766,587(+) GGAGT(A/G)CTCGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PROSER3 Gene

Variant ID Type Subtype PubMed ID
esv2718499 CNV deletion 23290073
nsv1123251 CNV deletion 24896259
nsv579422 CNV loss 21841781
nsv579423 CNV loss 21841781
nsv953286 CNV deletion 24416366

Variation tolerance for PROSER3 Gene

Gene Damage Index Score: 7.06; 80.31% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PROSER3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PROSER3 Gene

Disorders for PROSER3 Gene

Relevant External Links for PROSER3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for PROSER3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PROSER3 Gene

Publications for PROSER3 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 3 4 65
  2. A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. (PMID: 26638075) Gupta G.D. … Pelletier L. (Cell 2015) 3 65
  3. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3 65
  4. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4 65
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 65

Products for PROSER3 Gene

Sources for PROSER3 Gene

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