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Aliases for PROSER1 Gene

Aliases for PROSER1 Gene

  • Proline And Serine Rich 1 2 3
  • C13orf23 3 4
  • Chromosome 13 Open Reading Frame 23 2
  • Proline And Serine-Rich Protein 1 3
  • KIAA2032 4

External Ids for PROSER1 Gene

Previous HGNC Symbols for PROSER1 Gene

  • C13orf23

Previous GeneCards Identifiers for PROSER1 Gene

  • GC13M039585

Summaries for PROSER1 Gene

Entrez Gene Summary for PROSER1 Gene

  • This gene encodes a conserved protein containing proline and serine rich regions. These regions may be important in protein-protein interactions. [provided by RefSeq, Aug 2012]

GeneCards Summary for PROSER1 Gene

PROSER1 (Proline And Serine Rich 1) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PROSER1 Gene

Genomics for PROSER1 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for PROSER1 Gene

39,009,865 bp from pter
39,038,076 bp from pter
28,212 bases
Minus strand

Genomic View for PROSER1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PROSER1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PROSER1 Gene

No data available for Regulatory Elements for PROSER1 Gene

Proteins for PROSER1 Gene

  • Protein details for PROSER1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Proline and serine-rich protein 1
    Protein Accession:
    Secondary Accessions:
    • A6NJ97
    • Q6P2S2
    • Q7Z3X5
    • Q8N3D2
    • Q8N3P1
    • Q9H9M1

    Protein attributes for PROSER1 Gene

    944 amino acids
    Molecular mass:
    95698 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB14204.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAC67659.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for PROSER1 Gene


neXtProt entry for PROSER1 Gene

Proteomics data for PROSER1 Gene at MOPED

Post-translational modifications for PROSER1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PROSER1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for PROSER1 Gene

Domains for PROSER1 Gene

Protein Domains for PROSER1 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PROSER1: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PROSER1 Gene

Function for PROSER1 Gene

genes like me logo Genes that share phenotypes with PROSER1: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for PROSER1

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for PROSER1 Gene

Localization for PROSER1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PROSER1 Gene

Pathways for PROSER1 Gene

SuperPathways for PROSER1 Gene

No Data Available

Interacting Proteins for PROSER1 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000332034 Q86XN7-PRSR1_HUMAN for PROSER1 Gene via STRING I2D

Gene Ontology (GO) - Biological Process for PROSER1 Gene


No data available for Pathways by source for PROSER1 Gene

Transcripts for PROSER1 Gene

Unigene Clusters for PROSER1 Gene

Proline and serine rich 1:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for PROSER1

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PROSER1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b · 12c ^ 13a · 13b ^ 14a · 14b · 14c
SP1: - - -
SP2: -
SP3: - - - - - - - -
SP4: -
SP5: -

Relevant External Links for PROSER1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PROSER1 Gene

mRNA expression in normal human tissues for PROSER1 Gene

Protein differential expression in normal tissues for PROSER1 Gene

This gene is overexpressed in Placenta (69.0).

Integrated Proteomics: protein expression from ProteomicsDB, MOPED, and MaxQB for PROSER1 Gene

SOURCE GeneReport for Unigene cluster for PROSER1 Gene Hs.318526

genes like me logo Genes that share expressions with PROSER1: view

Expression partners for PROSER1 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for PROSER1 Gene

Orthologs for PROSER1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for PROSER1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia PROSER1 35
  • 76.25 (n)
  • 78.25 (a)
  • 78 (a)
(Canis familiaris)
Mammalia PROSER1 35
  • 84.75 (n)
  • 87.21 (a)
  • 87 (a)
(Mus musculus)
Mammalia Proser1 35
  • 79.22 (n)
  • 81.61 (a)
Proser1 16
Proser1 36
  • 80 (a)
(Pan troglodytes)
Mammalia PROSER1 35
  • 99.15 (n)
  • 99.05 (a)
  • 99 (a)
(Rattus norvegicus)
Mammalia Proser1 35
  • 78.03 (n)
  • 80.2 (a)
(Monodelphis domestica)
Mammalia PROSER1 36
  • 79 (a)
(Ornithorhynchus anatinus)
Mammalia PROSER1 36
  • 75 (a)
(Gallus gallus)
Aves PROSER1 35
  • 74.69 (n)
  • 74.65 (a)
  • 74 (a)
(Anolis carolinensis)
Reptilia PROSER1 36
  • 67 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia proser1 35
  • 62.34 (n)
  • 59.84 (a)
(Danio rerio)
Actinopterygii PROSER1 36
  • 48 (a)
Species with no ortholog for PROSER1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for PROSER1 Gene

Gene Tree for PROSER1 (if available)
Gene Tree for PROSER1 (if available)

Paralogs for PROSER1 Gene

Selected SIMAP similar genes for PROSER1 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with PROSER1: view

No data available for Paralogs for PROSER1 Gene

Variants for PROSER1 Gene

Sequence variations from dbSNP and Humsavar for PROSER1 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type MAF
rs747752 -- 39,017,069(+) TCTTT(C/T)CTACA intron-variant
rs1043348 -- 39,010,236(-) TTCAA(C/G)ATAGG utr-variant-3-prime
rs1043351 -- 39,010,154(-) ATATG(A/C)CAAAT utr-variant-3-prime
rs1326404 -- 39,024,258(+) AATTT(C/G)ACTGA intron-variant
rs1326405 -- 39,024,286(+) AAGCT(C/T)AATCT intron-variant

Relevant External Links for PROSER1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for PROSER1 Gene

Disorders for PROSER1 Gene

No disorders were found for PROSER1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for PROSER1 Gene

Publications for PROSER1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The DNA sequence and analysis of human chromosome 13. (PMID: 15057823) Dunham A. … Ross M.T. (Nature 2004) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination. (PMID: 17761849) Lee M.G. … Shiekhattar R. (Science 2007) 3

Products for PROSER1 Gene

Sources for PROSER1 Gene

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