PROP1 Gene
protein-coding GIFtS: 56
GCID: GC05M177419
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|
PROP paired-like homeobox 1(Previous names: prophet of Pit1, paired-like homeodomain transcription...)
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Aliases
for PROP1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| PROP Paired-Like Homeobox 11 2 | | Prophet Of Pit1, Paired-Like Homeodomain Transcription Factor1 2 | | Pituitary-Specific Homeodomain Factor2 3 | | PROP-12 3 | | CPHD22 5 | | Homeobox Protein Prophet Of Pit-12 |
Export aliases for PROP1 gene to outside databasesPrevious GC identifers: GC05M177574 GC05M178307 GC05M177487 GC05M177532 GC05M177351 GC05M172154 |
Summaries
for PROP1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PROP1:
This gene encodes a paired-like homeodomain transcription factor in the developing pituitary gland. Expression occursprior to and is required for expression of pou domain transcription factor 1, which is responsible for pituitarydevelopment and hormone expression. Mutations in this gene have been associated with combined pituitary hormonedeficiency-2 as well as deficiencies in luteinizing hormone, follicle-stimulating hormone, growth hormone, prolactin,and thyroid-stimulating hormone. (provided by RefSeq, Sep 2011)
UniProtKB/Swiss-Prot: PROP1_HUMAN, O75360Function: Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes andcaudomedial thyrotropes
Gene Wiki entry for PROP1
|
Genomic Views
for PROP1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000005.9 NC_018916.1 NT_023133.13
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PROP1 gene promoter:
Pax-5 Tal-1 p53 SREBP-1c STAT5A YY1 Gfi-1 SREBP-1b E47 SREBP-1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for PROP1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PROP1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 5q35.3 Ensembl cytogenetic band: 5q35.3 HGNC cytogenetic band: 5q35.3PROP1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 5 GeneLoc Exon Structure GeneLoc location for GC05M177419: view genomic region
(about GC identifiers)
Start:
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177,419,236 bp from pter |
End:
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177,423,243 bp from pter |
Size:
|
4,008 bases |
Orientation:
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minus strand |
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Proteins
for PROP1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PROP1_HUMAN, O75360 (See
protein sequence)Recommended Name: Homeobox protein prophet of Pit-1 Size: 226 amino acids; 24984 Da
Subcellular location: Nucleus (By similarity)Explore the universe of human proteins at neXtProt for PROP1: NX_O75360
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75360
PROP1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_006252.3
ENSEMBL proteins: ENSP00000311290
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005667 | transcription factor complex |
IEA | -- |
PROP1 for ontologies About GeneDecksing
PROP1 Antibody Products:
Assay Products for PROP1: |
Protein
Domains /
Families
for PROP1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PROP1 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O75360ProtoNet protein and cluster: O75360 1 Blocks protein family: IPB000047 Lambda and other repressor helix-turn-helix signature
UniProtKB/Swiss-Prot: PROP1_HUMAN, O75360Similarity: Belongs to the paired homeobox familySimilarity: Contains 1 homeobox DNA-binding domain |
Function
for PROP1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PROP1_HUMAN, O75360Function: Possibly involved in the ontogenesis of pituitary gonadotropes, as well as somatotropes, lactotropes andcaudomedial thyrotropes Genatlas biochemistry entry for PROP1:prophet of PIT1,pituitary-specific,paired-like homeo domain,transcription factor,specifically expressed in embryonicpituitary and in pituitary tumors,necessary for PIT1 (POU1F1) expression,homolog to murine Ames dwarf (df),involved inthe proper development of somatotrophs,lactotrophs,thyreotrophs and gonadotrophs
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PROP1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PROP1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: PROP1 (NM_006261) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PROP1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PROP1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PROP1 |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000976 | transcription regulatory region sequence-specific DNA binding |
IEA | -- | | GO:0003682 | chromatin binding |
IEA | -- | | GO:0003700 | sequence-specific DNA binding transcription factor activity |
IEA | -- | | GO:0005515 | protein binding |
-- | -- | | GO:0008013 | beta-catenin binding |
IEA | -- |
PROP1 for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for PROP1:
Animal Models:
Mouse knock-outs for PROP1: Prop1tm1Sac Prop1tm1Rsd
9 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Prop1):
PROP1 for phenotypes About GeneDecksing
|
Pathways & Interactions
for PROP1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PROP1
STRING Interaction
Network Preview (showing 3 interactants - click image to see more details)
5/6 Interacting proteins for PROP1 (O753603 ENSP000003112904) via UniProtKB, MINT, STRING, and/or I2D (see all 6)About this table
Gene Ontology (GO): 5/14 biological process terms (GO ID links to tree view) (see all 14): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000122 | negative regulation of transcription from RNA polymerase II promoter |
IEA | -- | | GO:0001568 | blood vessel development |
IEA | -- | | GO:0007417 | central nervous system development |
TAS | 9462743 | | GO:0009887 | organ morphogenesis |
-- | -- | | GO:0009953 | dorsal/ventral pattern formation |
IEA | -- |
PROP1 for ontologies About GeneDecksing
|
Drugs & Compounds
for PROP1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
PROP1 for compounds About GeneDecksing
 Browse Tocris compounds for PROP1
5 Novoseek chemical compound relationships for PROP1 gene About this table
Search CenterWatch for drugs/clinical trials and news about PROP1
|
Transcripts
for PROP1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PROP1 gene: NM_006261.4 Unigene Cluster for PROP1: PROP paired-like homeobox 1 Hs.158301 Unigene Representative Sequence: NM_0062611 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000308304(uc003mif.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PROP1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PROP1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: PROP1 (NM_006261) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PROP1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PROP1 |
Additional cDNA sequence: AF076215.1 BC069076.1 1 DOTS entry: DT.92030461 3 AceView cDNA sequences: NM_006261 BC069076 AF076215
GeneLoc Exon Structure
|
Expression
for PROP1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PROP1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTGAATTCTC
About this image
See PROP1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PROP1
SOURCE GeneReport for Unigene cluster: Hs.158301
UniProtKB/Swiss-Prot: PROP1_HUMAN, O75360Tissue specificity: Expressed specifically in embryonic pituitary
SABiosciences Expression via Pathway-Focused PCR Arrays including PROP1:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PROP1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PROP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PROP1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PROP1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PROP1 |
Orthologs
for PROP1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for PROP1 gene from 5/14 species (see all 14) About this table
ENSEMBL Gene Tree for PROP1 (if available)
TreeFam Gene Tree for PROP1 (if available) |
Paralogs
for PROP1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PROP1 gene
- GSC2 OTX22 HESX12 ARGFX2 DMBX12 GSC22 SEBOX2 MIXL12
- OTX12 CRX2
8 SIMAP similar genes for PROP1 using alignment to 1 protein entry: PROP1_HUMAN:DUX1 PRRX1 NKX2-5 POU6F1 SHOX2 DUX2
HOXB1 RAX2
PROP1 for paralogs About GeneDecksing
|
Genomic Variants
for PROP1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 5 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PROP1 (177419236 - 177423243 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for PROP1
2 CNVs: 93380 81145
Human Gene Mutation Database (HGMD): PROP1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PROP1 |
|
Disorders
/ Diseases
for PROP1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PROP1 for disorders About GeneDecksing
OMIM gene information: 601538
OMIM disorders: 262600
UniProtKB/Swiss-Prot: PROP1_HUMAN, O75360
Defects in PROP1 are the cause of pituitary hormone deficiency combined type 2 (CPHD2) [MIM:262600]; alsoknown as pituitary dwarfism III. It is characterized by impaired production of growth hormone (GH) and one or more ofthe other five anterior pituitary hormones
20/26  diseases for PROP1 (see all 26): About MalaCardscombined pituitary hormone deficiency pituitary hormone deficiency borjeson-forssman-lehmann syndrome pituitary hormone deficiency, combined 2
growth hormone deficiency acth deficiency short stature thyroiditis
neonatal thyrotoxicosis delayed puberty kallmann syndrome panhypopituitarism
pituitary adenoma hypopituitarism pituitary hypoplasia craniopharyngioma
dwarfism pituitary tumor klinefelter's syndrome hypogonadism
8 diseases from the University of Copenhagen DISEASES database for PROP1:Hypopituitarism Pituitary hypoplasia Hypogonadism Klinefelter's syndrome
Hypothyroidism Neonatal thyrotoxicosis Holoprosencephaly Anosognosia 10/23 Novoseek disease relationships for PROP1 gene (see all 23) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| panhypopituitarism |
97.1 |
71 |
11549674 (4), 12006708 (2), 12812307 (2), 10084575 (2) (see all 46) |
| septo-optic dysplasia |
92.2 |
4 |
18291347 (1), 10727999 (1), 15670191 (1), 17315526 (1) |
| tsh deficiency |
92 |
5 |
15941866 (1), 20381582 (1), 16735499 (1), 18174732 (1) |
| hormone deficiency |
90.7 |
18 |
11549703 (3), 17526936 (2), 9920061 (1), 10946868 (1) (see all 14) |
| hypopituitarism |
89.3 |
15 |
12717343 (2), 15963055 (2), 9920061 (1), 15472232 (1) (see all 13) |
| acth deficiency |
82.8 |
3 |
12780757 (1), 17162714 (1), 12717343 (1) |
| growth hormone deficiency |
75.1 |
4 |
17526936 (2), 17642419 (1), 12414875 (1) |
| kallmann syndrome |
73.1 |
2 |
10714361 (1), 12536356 (1) |
| short stature |
69.5 |
3 |
16909451 (1), 20181723 (1), 12519826 (1) |
| dwarfism |
66.9 |
7 |
15531542 (1), 10773688 (1), 19524124 (1), 16909451 (1) (see all 5) |
GeneTests: PROP1
PROP1-Related Combined Pituitary Hormone Deficiency
Genetic Association Database (GAD): PROP1
Human Genome Epidemiology (HuGE) Navigator: PROP1 (10 documents)
Export disorders for PROP1 gene to outside databases
|
Publications
for PROP1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PROP1 gene, integrated from 9 sources (see all 155):
(articles sorted by number of sources associating them with PROP1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Mutations in PROP1 cause familial combined pituitary hormone deficiency. (PubMed id 9462743)1, 2, 3, 9 Wu W.... Rosenfeld M.G. (1998)
- Molecular analysis of novel PROP1 mutations associated with combined pituitary hormone deficiency (CPHD). (PubMed id 19128366)1, 2, 9 Kelberman D.... Dattani M.T. (2009)
- Combined pituitary hormone deficiency caused by a novel mutation of a highly conserved residue (F88S) in the homeodomain of PROP-1. (PubMed id 10946881)1, 2, 9 Osorio M.G....Arnhold I.J. (2000)
- Mutations within the transcription factor PROP1 are rare in a cohort of patients with sporadic combined pituitary hormone deficiency (CPHD). (PubMed id 15963055)1, 4, 9 Turton J.P....Dattani M.T. (2005)
- Familial combined pituitary hormone deficiency due to a novel mutation R99Q in the hot spot region of Prophet of Pit-1 presenting as constitutional growth delay. (PubMed id 12519826)1, 2, 9 Vieira T.C....Abucham J. (2003)
- PROP1 gene screening in patients with multiple pituitary hormone deficiency reveals two sites of hypermutability and a high incidence of corticotroph deficiency. (PubMed id 11549703)1, 2, 9 Vallette-Kasic S.... Brue T. (2001)
- Phenotypic variability in familial combined pituitary hormone deficiency caused by a PROP1 gene mutation resulting in the substitution of Arg-->Cys at codon 120 (R120C). (PubMed id 9768691)1, 2, 9 Fluck C....Mullis P.E. (1998)
- A familial form of congenital hypopituitarism due to a PROP1 mutation in a large kindred: phenotypic and in vitro functional studies. (PubMed id 15531542)1, 2, 9 Reynaud R....Brue T. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Human Prop-1: cloning, mapping, genomic structure. Mutations in familial combined pituitary hormone deficiency. (PubMed id 9824293)1, 2 Duquesnoy P.... Amselem S. (1998)
|
External Searches for PROP1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PROP1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PROP1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PROP1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for PROP1 gene:
Search GeneIP for patents involving PROP1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PROP1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for PROP1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PROP1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PROP1 | | | OriGene Protein Over-expression Lysate for PROP1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PROP1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PROP1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PROP1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for PROP1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PROP1 | | OriGene Custom Protein Services for PROP1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PROP1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PROP1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PROP1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PROP1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PROP1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PROP1 |
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 |  |  |  | |
| | | | Search Tocris compounds for PROP1 |
| |  |  |  |  | | | | |
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 | | | PROP1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PROP1 |
|  |  |  | | | | Search ThermoFisher Antibodies for PROP1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PROP1 |
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