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Aliases for PRNT Gene

Subcategory (RNA class) for PRNT Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for PRNT Gene

  • Prion Protein (Testis Specific) 2 3 5
  • M8 Protein 2
  • Protein M8 4
  • M8 3

External Ids for PRNT Gene

Previous GeneCards Identifiers for PRNT Gene

  • GC00U991277

Summaries for PRNT Gene

GeneCards Summary for PRNT Gene

PRNT (Prion Protein (Testis Specific)) is an RNA Gene, and is affiliated with the ncRNA class. Diseases associated with PRNT include Creutzfeldt-Jakob Disease and Variola Major.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRNT Gene

Genomics for PRNT Gene

Regulatory Elements for PRNT Gene

Enhancers for PRNT Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around PRNT on UCSC Golden Path with GeneCards custom track

Genomic Location for PRNT Gene

Chromosome:
20
Start:
4,731,282 bp from pter
End:
4,740,668 bp from pter
Size:
9,387 bases
Orientation:
Minus strand

Genomic View for PRNT Gene

Genes around PRNT on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRNT Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRNT Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRNT Gene

Proteins for PRNT Gene

  • Protein details for PRNT Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q86SH4-PRNT_HUMAN
    Recommended name:
    Putative testis-specific prion protein
    Protein Accession:
    Q86SH4
    Secondary Accessions:
    • B2RPD9
    • B7ZBI9

    Protein attributes for PRNT Gene

    Size:
    94 amino acids
    Molecular mass:
    10756 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This putative protein is only present in primates and not in other mammals.

neXtProt entry for PRNT Gene

Proteomics data for PRNT Gene at MOPED

Post-translational modifications for PRNT Gene

Other Protein References for PRNT Gene

No data available for DME Specific Peptides for PRNT Gene

Domains & Families for PRNT Gene

Protein Domains for PRNT Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for PRNT Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PRNT: view

No data available for Gene Families and UniProtKB/Swiss-Prot for PRNT Gene

Function for PRNT Gene

Phenotypes for PRNT Gene

genes like me logo Genes that share phenotypes with PRNT: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRNT Gene

Localization for PRNT Gene

Subcellular locations from UniProtKB/Swiss-Prot for PRNT Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for PRNT Gene COMPARTMENTS Subcellular localization image for PRNT gene
Compartment Confidence
extracellular 5

No data available for Gene Ontology (GO) - Cellular Components for PRNT Gene

Pathways & Interactions for PRNT Gene

SuperPathways for PRNT Gene

No Data Available

Interacting Proteins for PRNT Gene

Gene Ontology (GO) - Biological Process for PRNT Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PRNT Gene

Drugs & Compounds for PRNT Gene

No Compound Related Data Available

Transcripts for PRNT Gene

mRNA/cDNA for PRNT Gene

(1) REFSEQ mRNAs :
(8) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for PRNT Gene

Prion protein (testis specific):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PRNT Gene

ExUns: 1a · 1b ^ 2
SP1: -
SP2:

Relevant External Links for PRNT Gene

GeneLoc Exon Structure for
PRNT
ECgene alternative splicing isoforms for
PRNT

Expression for PRNT Gene

mRNA expression in normal human tissues for PRNT Gene

mRNA differential expression in normal tissues according to GTEx for PRNT Gene

This gene is overexpressed in Testis (x52.9).

SOURCE GeneReport for Unigene cluster for PRNT Gene Hs.126516

mRNA Expression by UniProt/SwissProt for PRNT Gene

Q86SH4-PRNT_HUMAN
Tissue specificity: Specifically expressed in adult testis.
genes like me logo Genes that share expression patterns with PRNT: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for PRNT Gene

Orthologs for PRNT Gene

Evolution for PRNT Gene

ENSEMBL:
Gene Tree for PRNT (if available)
TreeFam:
Gene Tree for PRNT (if available)

No data available for Orthologs for PRNT Gene

Paralogs for PRNT Gene

No data available for Paralogs for PRNT Gene

Variants for PRNT Gene

Sequence variations from dbSNP and Humsavar for PRNT Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs7270737 - 4,732,528(+) ATGCA(C/G)TATGG nc-transcript-variant
rs1040872 -- 4,733,581(-) ACAGA(C/G)GCCTG intron-variant
rs743252 -- 4,740,021(+) TCCCA(C/T)ACCCA intron-variant
rs1931971 -- 4,735,469(+) cccag(A/C)taatt intron-variant
rs1999664 -- 4,740,502(-) CATAG(A/G)ATCTT intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for PRNT Gene

Variant ID Type Subtype PubMed ID
nsv512602 CNV Loss 21212237

Variation tolerance for PRNT Gene

Gene Damage Index Score: 0.26; 5.79% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for PRNT Gene

Disorders for PRNT Gene

MalaCards: The human disease database

(3) MalaCards diseases for PRNT Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
creutzfeldt-jakob disease
  • creutzfeldt-jakob disease, variant
variola major
  • smallpox
korean hemorrhagic fever
  • hemorrhagic fever with renal syndrome
- elite association - COSMIC cancer census association via MalaCards
Search PRNT in MalaCards View complete list of genes associated with diseases

Relevant External Links for PRNT

Genetic Association Database (GAD)
PRNT
Human Genome Epidemiology (HuGE) Navigator
PRNT
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PRNT
genes like me logo Genes that share disorders with PRNT: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PRNT Gene

Publications for PRNT Gene

  1. Genomic characterization of the human prion protein (PrP) gene locus. (PMID: 12514748) Makrinou E. … Antoniou M. (Mamm. Genome 2002) 2 3 4 23 67
  2. Genomic assessment of the evolution of the prion protein gene family in vertebrates. (PMID: 20206252) Harrison P.M. … Kumar M. (Genomics 2010) 3
  3. Comparative genomic analysis of prion genes. (PMID: 17199895) Premzl M. … Gamulin V. (BMC Genomics 2007) 3
  4. Comparative genomic organization of the human and bovine PRNP locus. (PMID: 16460908) Choi S.-H. … Park H.-S. (Genomics 2006) 3
  5. Polymorphic microsatellite sites in the PRNP region point to excess of homozygotes in Creutzfeldt-Jakob disease patients. (PMID: 16889908) Geldermann H. … Zerr I. (Gene 2006) 3

Products for PRNT Gene

Sources for PRNT Gene

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