PRMT7 Gene
protein-coding GIFtS: 50
GCID: GC16P068344
|
|
protein arginine methyltransferase 7
| |
Aliases for PRMT7 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Protein Arginine Methyltransferase 71 2 | | Protein Arginine N-Methyltransferase 72 | | KIAA19331 3 | | EC 2.1.1.-3 | | Histone-Arginine N-Methyltransferase PRMT72 3 | | EC 2.1.1.1253 | | [Myelin Basic Protein]-Arginine N-Methyltransferase PRMT72 3 | | EC 2.1.1.1263 | | FLJ106401 | | EC 2.1.18 | | Myelin Basic Protein-Arginine N-Methyltransferase2 | | |
Export aliases for PRMT7 gene to outside databasesPrevious GC identifers: GC16P068122 GC16P066902 GC16P054218 |
Summaries for PRMT7 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for PRMT7: Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, suchas PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signaltransduction, RNA transport, and RNA splicing (Miranda et al., 2004 (PubMed 15044439)).(supplied by OMIM, Mar 2008) UniProtKB/Swiss-Prot: ANM7_HUMAN, Q9NVM4Function: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) andsymmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetricaldimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); suchmethylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates thesymmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited byCTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading torecruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Alsoable to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of suchresults is however unclear in vivo
|
Genomic Views for PRMT7 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the PRMT7 gene promoter: GR Pax-5 AML1a POU3F1 RORalpha1 PPAR-gamma1 ARP-1 GR-alpha PPAR-gamma2 MRF-2 Other transcription factors
Search SABiosciences Chromatin IP Primers for PRMT7
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PRMT7 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q22.1 Ensembl cytogenetic band: 16q22.1 HGNC cytogenetic band: 16q22.1PRMT7 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P068344: view genomic region
(about GC identifiers)
Start:
|
68,344,877 bp from pter |
End:
|
68,392,466 bp from pter |
Size:
|
47,590 bases |
Orientation:
|
plus strand |
|
Proteins for PRMT7 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: ANM7_HUMAN, Q9NVM4 (See
protein sequence)Recommended Name: Protein arginine N-methyltransferase 7 Size: 692 amino acids; 78459 Da
Subunit: Homodimer and heterodimer (By similarity). Interacts with CTCFL (By similarity). Interacts with PRMT5 andSNRPD3
Subcellular location: Cytoplasm, cytosol. Nucleus
Miscellaneous: May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used fortesticular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers.Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT)
Sequence caution: Sequence=BAB14215.1; Type=Erroneous initiation;
Secondary accessions: B3KPR0 B3KUG9 B4E379 Q96PV5 Q9H9L0Alternative splicing: 4 isoforms: Q9NVM4-1 Q9NVM4-2 Q9NVM4-3 Q9NVM4-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for PRMT7: NX_Q9NVM4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NVM4 2 DME Specific Peptides for PRMT7 (Q9NVM4)
PRMT7 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001171753.1 NP_061896.1 ENSEMBL proteins: ENSP00000454980 ENSP00000456364 ENSP00000456190 ENSP00000455538 ENSP00000455705 ENSP00000456848 ENSP00000414716 ENSP00000457381 ENSP00000343103 ENSP00000454776 ENSP00000409324 ENSP00000345775 Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
PRMT7 for ontologies About GeneDecksing
PRMT7 Antibody Products: Assay Products for PRMT7: |
Protein
Domains / Families for PRMT7 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PRMT7 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NVM4ProtoNet protein and cluster: Q9NVM4 UniProtKB/Swiss-Prot: ANM7_HUMAN, Q9NVM4Similarity: Belongs to the protein arginine N-methyltransferase family. PRMT7 subfamily |
Function for PRMT7 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: ANM7_HUMAN, Q9NVM4Function: Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) andsymmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetricaldimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); suchmethylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates thesymmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited byCTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading torecruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Alsoable to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of suchresults is however unclear in vivoCatalytic activity: S-adenosyl-L-methionine + arginine-[histone] = S-adenosyl-L-homocysteine +N(omega)-methyl-arginine-[histone]Catalytic activity: S-adenosyl-L-methionine + [myelin basic protein]-arginine = S-adenosyl-L-homocysteine + [myelinbasic protein]-N(omega)-methyl-arginineEnzyme Numbers (IUBMB): EC 2.1.1.1261 EC 2.1.1.-1 EC 2.1.12 EC 2.1.1.1251
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PRMT7 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PRMT7 (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): PRMT7 (NM_019023) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PRMT7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRMT7  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRMT7 |
Gene Ontology (GO): 5/10 molecular function terms (GO ID links to tree view) (see all 10): About this table
PRMT7 for ontologies About GeneDecksing
Animal Models: 1 MGI mutant phenotype (inferred from 1 allele ) (MGI details for Prmt7):
PRMT7 for phenotypes About GeneDecksing
|
Pathways & Interactions for PRMT7 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PRMT7
STRING Interaction
Network Preview (showing 5 interactants - click image to see 10)
 5/26 Interacting proteins for PRMT7 (Q9NVM43 ENSP000003431034) via UniProtKB, MINT, STRING, and/or I2D (see all 26)About this table
Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13): About this table
PRMT7 for ontologies About GeneDecksing
|
Drugs & Compounds for PRMT7 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
PRMT7 for compounds About GeneDecksing
Browse Tocris compounds for PRMT7 4 Novoseek chemical compound relationships for PRMT7 gene About this table
Search CenterWatch for drugs/clinical trials and news about PRMT7 / ANM7 
|
Transcripts for PRMT7 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for PRMT7 gene (2 alternative transcripts): NM_001184824.1 NM_019023.2 Unigene Cluster for PRMT7: Protein arginine methyltransferase 7 Hs.653193 [show with all ESTs]Unigene Representative Sequence: AB06752018/28 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 28): ENST00000566657 ENST00000562381 ENST00000565745 ENST00000569571 ENST00000566341 ENST00000564050 ENST00000569047 ENST00000449359(uc010vlg.2) ENST00000564441 ENST00000565356 ENST00000562050 ENST00000563520 ENST00000565983 ENST00000339507(uc002evy.2) ENST00000568975 ENST00000563562 ENST00000561806 ENST00000562456
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PRMT7 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PRMT7 (see all 3) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): PRMT7 (NM_019023) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PRMT7 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRMT7  |
Additional cDNA sequence: AB067520.1 AK001502.1 AK022739.1 AK056647.1 AK097175.1 AK304605.1 BC000146.1 BC127884.1 23 DOTS entries: DT.212531 DT.97844435 DT.208696 DT.95166029 DT.100773462 DT.100829738 DT.91736735 DT.91788226 DT.100702432 DT.100776289 DT.100776290 DT.91736740 DT.95360158 DT.65287875 DT.101967897 DT.92020339 DT.92420664 DT.97844433 DT.99999354 DT.100716961 DT.100767306 DT.95166027 DT.95215598 24/152 AceView cDNA sequences (see all 152): AL698140 BM547362 BF224136 BU187820 BM922828 BP364420 BQ070378 AU125909 BQ053883 CR604457 BF438197 BF590702 H52857 BF062807 BU189250 BG675458 BP346424 BU738337 BP345733 AK022739 AI288686 AW593557 NM_019023 AI435996 GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for PRMT7 (see all 8) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14a | · | 14b | ^ | 15a | · | 15b | ^ | 16 | ^ | 17a | · | 17b | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |
| SP3: | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for PRMT7
|
Expression for PRMT7 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PRMT7 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CAGATACCCC
About this image See PRMT7 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for PRMT7
SOURCE GeneReport for Unigene cluster: Hs.653193 SABiosciences Expression via Pathway-Focused PCR Array including PRMT7:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PRMT7 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PRMT7 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PRMT7 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PRMT7 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRMT7 |
Orthologs for PRMT7 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for PRMT7 gene from 8/25 species (see all 25) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
PRMT71 |
protein arginine methyltransferase 7 |
67.93(n) 69.05(a) |
  |
415620 NM_001005831.1 NP_001005831.1 |
lizard (Anolis carolinensis) |
Reptilia |
PRMT76 |
-- |
70(a) |
1 ↔ 1 |
LGc(6753811-6789633) |
African clawed frog (Xenopus laevis) |
Amphibia |
MGC689792 |
hypothetical protein MGC68979 |
76(n) |
  |
BC059311.1 |
zebrafish (Danio rerio) |
Actinopterygii |
zgc661722 |
hypothetical protein MGC66172 |
75.39(n) |
  |
393475 BC044492.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
Art71 |
Arginine methyltransferase 7 |
50.65(n) 38.7(a) |
  |
37664 NM_137909.3 NP_611753.4 |
worm (Caenorhabditis elegans) |
Secernentea |
prmt-71 |
Protein PRMT-7 |
43.66(n) 34.59(a) |
  |
172727 NM_060035.2 NP_492436.1 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
PRMT71 |
protein arginine N-methyltransferase 7 |
44.14(n) 33.72(a) |
  |
827358 NM_117758.2 NP_567508.1 |
rice (Oryza sativa) |
Liliopsida |
Os06g01055001 |
hypothetical protein |
44.29(n) 33.96(a) |
  |
4339860 NM_001063091.1 NP_001056556.1 |
ENSEMBL Gene Tree for PRMT7 (if available) TreeFam Gene Tree for PRMT7 (if available)  |
Paralogs for PRMT7 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for PRMT7 gene
- PRMT102
1 SIMAP similar gene for PRMT7 using alignment to 8 protein entries: ANM7_HUMAN (see all proteins):PRMT1
PRMT7 for paralogs About GeneDecksing
|
Genomic Variants for PRMT7 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 16 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for PRMT7 (68344877 - 68392466 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for PRMT7: -- Human Gene Mutation Database (HGMD): PRMT7
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PRMT7 |
|
Disorders
/ Diseases for PRMT7 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PRMT7 for disorders About GeneDecksing
OMIM gene information: 610087
OMIM disorders: --
9 diseases for PRMT7: About MalaCardsgerm cell tumor intrahepatic cholangiocarcinoma testicular cancer cholangiocarcinoma homocysteine lung cancer sarcoma cholesterol leukemia Export disorders for PRMT7 gene to outside databases
|
Publications for PRMT7 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PRMT7 gene, integrated from 9 sources (see all 42): (articles sorted by number of sources associating them with PRMT7) | |  | Utopia: connect your pdf to the dynamic world of online information |
- PRMT7 is a member of the protein arginine methyltransferase family with a distinct substrate specificity. (PubMed id 15044439)1, 2, 3, 9 Miranda T.B.... Clarke S. (2004)
- Accurate localization and relative quantification of arginine methylation using nanoflow liquid chromatography coupled to electron transfer dissociation and orbitrap mass spectrometry. (PubMed id 19110445)1, 2, 9 Wang H.... Qu J. (2009)
- Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins. (PubMed id 17709427)1, 2, 9 Gonsalvez G.B....Matera A.G. (2007)
- PRMT7, a new protein arginine methyltransferase that synthesizes symmetric dimethylarginine. (PubMed id 15494416)1, 2 Lee J.H....Pestka S. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. (PubMed id 11572484)1, 2 Nagase T....Ohara O. (2001)
- PRMT8, a new membrane-bound tissue-specific member of the protein arginine methyltransferase family. (PubMed id 16051612)1, 9 Lee J....Bedford M.T. (2005)
- Protein arginine methyltransferase 7 regulates cellular response to DNA damage by methylating promoter histones H2A and H4 of the polymerase delta catalytic subunit gene, POLD1. (PubMed id 22761421)1 Karkhanis V.... Sif S. (2012)
- Protein arginine methyltransferase 1-directed methylat ion of Kaposi sarcoma-associated herpesvirus latency-associated nuclear antigen. (PubMed id 22179613)1 Campbell M....Izumiya Y. (2012)
|
External Searches for PRMT7 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing PRMT7 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PRMT7 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing PRMT7 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for PRMT7 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PRMT7 gene: Search GeneIP for patents involving PRMT7
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for PRMT7 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for PRMT7 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PRMT7 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PRMT7 | | OriGene Protein Over-expression Lysate for PRMT7 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for PRMT7 | | Browse 3'-UTR reporter clones for miRNA target validation | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PRMT7 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PRMT7 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for PRMT7 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for PRMT7 | | OriGene Custom Protein Services for PRMT7 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PRMT7 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PRMT7 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PRMT7 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PRMT7 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PRMT7 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PRMT7 |
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| | | Search Tocris compounds for PRMT7 |
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 | | PRMT7 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRMT7 |
|  |  |  | | | ThermoFisher Antibodies for PRMT7 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRMT7 |
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