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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PRLHR Gene

protein-coding   GIFtS: 56
GCID: GC10M120344

prolactin releasing hormone receptor

(Previous name: G protein-coupled receptor 10 )
(Previous symbol: GPR10)
 Explore 9 diseases affiliated with
PRLHR via our new
 Human Malady Compendium 
Biological research products
for PRLHR
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Prolactin Releasing Hormone Receptor1 2     G-Protein Coupled Receptor 102 3
GPR101 2 3 5     HGR31
G Protein-Coupled Receptor 101 2     Prolactin Releasing Peptide Receptor2
PrRP Receptor2 3     Prolactin-Releasing Hormone Receptor2
GR32 3     Prolactin-Releasing Peptide Receptor2
PrRPR2 3     

External Ids:    HGNC: 44641   Entrez Gene: 28342   Ensembl: ENSG000001199737   OMIM: 6008955   UniProtKB: P496833   

Export aliases for PRLHR gene to outside databases

Previous GC identifer: GC10M113981


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PRLHR:
PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed
in anterior pituitary (Ozawa et al., 2002 (PubMed 11923475)).(supplied by OMIM, Mar 2008)

UniProtKB/Swiss-Prot: PRLHR_HUMAN, P49683
Function: Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and
pain-signal processing

Gene Wiki entry for PRLHR (Prolactin-releasing peptide receptor)


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.1  NT_030059.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PRLHR gene promoter:
         FOXF2   Pax-5   NRSF form 1   AP-2gamma   NRSF form 2   CREB   FOXC1   HFH-1   deltaCREB   COMP1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPRLHR promoter sequence
   Search SABiosciences Chromatin IP Primers for PRLHR

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PRLHR


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q26.13   Ensembl cytogenetic band:  10q26.11   HGNC cytogenetic band: 10q25.3-q26

PRLHR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PRLHR gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M120344:  view genomic region     (about GC identifiers)

Start:
120,352,916 bp from pter      End:
120,355,160 bp from pter
Size:
2,245 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: PRLHR_HUMAN, P49683 (See protein sequence)
Recommended Name: Prolactin-releasing peptide receptor  
Size: 370 amino acids; 41121 Da
Subunit: Interacts through its C-terminal region with the PDZ domain-containing proteins GRIP1, GRIP2 and PICK1.
Interacts with PDZ domains 4 and 5 of GRIP1 and with the PDZ domain of PICK1
Subcellular location: Cell membrane; Multi-pass membrane protein
Sequence caution: Sequence=AAC50504.1; Type=Frameshift; Positions=168, 175;
Secondary accessions: O75194 Q502U8 Q5VXR9

Explore the universe of human proteins at neXtProt for PRLHR: NX_P49683

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P49683

  • PRLHR Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_004239.1  
    ENSEMBL proteins: 
     ENSP00000358167   ENSP00000239032  
    Reactome Protein details: P49683
    Human Recombinant Protein Products: 
    EMD Millipore Purified and/or Recombinant PRLHR Protein
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    Novus Biologicals PRLHR Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Uscn

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0005887integral to plasma membrane TAS8666380


    PRLHR for ontologies           About GeneDecksing



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    Browse ELISAs and CLIAs at Uscn


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    PRLHR for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR001402 Prolrel_pep_rcpt
     IPR017452 GPCR_Rhodpsn_7TM
     IPR000276 GPCR_Rhodpsn

    Graphical View of Domain Structure for InterPro Entry P49683

    ProtoNet protein and cluster: P49683

    1 Blocks protein family: IPB001402 Probable G protein-coupled receptor GPR10 signature

    UniProtKB/Swiss-Prot: PRLHR_HUMAN, P49683
    Similarity: Belongs to the G-protein coupled receptor 1 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: PRLHR_HUMAN, P49683
    Function: Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and
    pain-signal processing
    Induction: Repressed by bromocriptine, a dopamine agonist

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PRLHR
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate PRLHR:
    hsa-miR-877* hsa-miR-642a hsa-miR-1207-3p hsa-miR-3652
    SwitchGear 3'UTR luciferase reporter plasmidPRLHR 3' UTR sequence
    Inhib. RNA
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    OriGene shRNA RFP: PRLHR
    OriGene siRNA: PRLHR
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    Gene Editing
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    Clone
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRLHR

    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004930G-protein coupled receptor activity TAS8666380
    GO:0004983neuropeptide Y receptor activity IEA--
    GO:0008188neuropeptide receptor activity TAS9607765
    GO:0017046peptide hormone binding ----


    PRLHR for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-outs for PRLHR: Prlhrtm1Dgen Prlhrtm1Map
         5 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Prlhr):
     adipose tissue  behavior/neurological  growth/size  homeostasis/metabolism  integument 

    PRLHR for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Class A/1 (Rhodopsin-like receptors)
    Class A/1 (Rhodopsin-like receptors)1.00
    GPCRs, Class A Rhodopsin-like0.41
    GPCR ligand binding0.75
    Neuroactive ligand-receptor interaction0.38
    Peptide ligand-binding receptors0.61
    2Signaling by GPCR
    Signaling by GPCR1.00
    Signal Transduction0.56
    3Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q
    Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for PRLHR
        Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q


    1 BioSystems Pathway for PRLHR 
        GPCRs, Class A Rhodopsin-like

    5        Reactome Pathways for PRLHR
        Peptide ligand-binding receptors
    Signal Transduction
    Signaling by GPCR
    GPCR ligand binding
    Class A/1 (Rhodopsin-like receptors)


    1         Kegg Pathway  (Kegg details for PRLHR):
        Neuroactive ligand-receptor interaction


    PRLHR for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PRLHR

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/6 Interacting proteins for PRLHR (P496832, 3 ENSP000002390324) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GRIP2Q9C0E42, 3MINT-1785769 I2D: score=1 
    GRIP1Q9Y3R02, 3, ENSP000003810984MINT-1785743 MINT-1785849 I2D: score=2 STRING: ENSP00000381098
    PICK1Q9NRD52, 3, ENSP000003494654MINT-1785875 MINT-1785826 I2D: score=3 STRING: ENSP00000349465
    PRLHP812773, ENSP000001655244I2D: score=1 STRING: ENSP00000165524
    SNTA1Q134243I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007186G-protein coupled receptor signaling pathway TAS8666380
    GO:0007218neuropeptide signaling pathway TAS9607765
    GO:0007565female pregnancy TAS9607765
    GO:0007631feeding behavior IEA--
    GO:0042445hormone metabolic process IEA--


    PRLHR for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    PRLHR for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PRLHR
    1 Novoseek chemical compound relationship for PRLHR gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    glutamate 5.8 1 11641419 (1)

    Search CenterWatch for drugs/clinical trials and news about PRLHR 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PRLHR gene: 
    NM_004248.2  

    Unigene Cluster for PRLHR:

    Prolactin releasing hormone receptor
    Hs.248119  [show with all ESTs]
    Unigene Representative Sequence: NM_004248
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000369169(uc021pzm.1) ENST00000239032(uc001ldp.1)

    miRNA
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    hsa-miR-877* hsa-miR-642a hsa-miR-1207-3p hsa-miR-3652
    SwitchGear 3'UTR luciferase reporter plasmidPRLHR 3' UTR sequence
    Inhib. RNA
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PRLHR
    Clone
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    GenScript: all cDNA clones in your preferred vector: PRLHR (NM_004248)
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PRLHR
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PRLHR

    Additional cDNA sequence: 

    AB015745.1 AK290461.1 AK313269.1 BC095539.1 BC101490.1 BC101492.1 EF577402.1 

    2 DOTS entries:

    DT.121243221  DT.102820834 

    12 AceView cDNA sequences:

    AB015745 CR607650 NM_004248 BX471829 CN839277 CN838339 CN842565 CN839221 
    AL528009 CN838171 AL563031 CN842623 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PRLHR expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ATATTGCTTA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See PRLHR Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PRLHR

    SOURCE GeneReport for Unigene cluster: Hs.248119

    UniProtKB/Swiss-Prot: PRLHR_HUMAN, P49683
    Tissue specificity: Only detected in the pituitary gland and in all cell types of pituitary adenomas

        SABiosciences Expression via Pathway-Focused PCR Arrays including PRLHR: 
              G Protein Coupled Receptors 384HT in human mouse rat
              Obesity in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRLHR

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for PRLHR gene from 7/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Prlhr1 , 5 prolactin releasing hormone receptor1, 5 86.19(n)1
    90.74(a)1
      19 (56.52 cM)5
    2262781  NM_201615.21  NP_963909.21 
     604667335 
    chicken
    (Gallus gallus)
    Aves PRLHR1 prolactin releasing hormone receptor 61.16(n)
    59.5(a)
      428985  NM_001012295.1  NP_001012295.1 
    lizard
    (Anolis carolinensis)
    Reptilia PRLHR6
    --
    (see all 4)
    --
    65(a)
    55(a)
    (see all 4)
    1 ↔ 1
    possible ortholog
    (see all 4)
    GL343206.1(80785-82599)
    GL343206.1(98139-99662)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia BQ524111.12   -- 79.66(n)    BQ524111.1 
    zebrafish
    (Danio rerio)
    Actinopterygii prlhr2a1 prolactin releasing hormone receptor 2a 60.52(n)
    56.56(a)
      654782  NM_001039526.1  NP_001034615.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta sNPF-R1 short neuropeptide F receptor 52.93(n)
    39.09(a)
      40195  NM_079452.2  NP_524176.1 
    worm
    (Caenorhabditis elegans)
    Secernentea npr-61 Protein NPR-6 45.36(n)
    33.93(a)
      185623  NM_077324.4  NP_509725.2 


    ENSEMBL Gene Tree for PRLHR (if available)
    TreeFam Gene Tree for PRLHR (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PRLHR gene
    GPR832  HCRTR22  NPFFR22  PPYR12  NPY5R2  TACR12  TACR32  NPY1R2  
    QRFPR2  NPFFR12  NPY2R2  HCRTR12  TACR22  
    18/25 SIMAP similar genes for PRLHR using alignment to 2 protein entries:     PRLHR_HUMAN (see all proteins) (see all similar genes):
    NPY1R    NPY2R    GALR1    GPR83    NPFFR2    PPYR1
    PROKR2    BRS3    SSTR1    SSTR4    TACR1    TACR3
    NPY6R    OPRL1    KISS1R    PROKR1    TACR2    NMBR

    PRLHR for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/113 NCBI SNPs in PRLHR are shown (see all 113    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1922858701,2
    --120352495(+) GTTAAA/GGTGAT 1 -- ds50010--------
    rs22259161,2
    H--120352551(-) CTCCAG/CGGTTA 1 -- ds50014Minor allele frequency- C:0.00NS EA 396
    rs1382694441,2
    --120352556(+) CTGGAC/GGTAAT 1 -- ds50010--------
    rs1496409921,2
    --120352611(+) GTTCTA/GTCCTT 1 -- ds50010--------
    rs1468930071,2
    --120352618(+) CCTTAA/GGTAAA 1 -- ds50010--------
    rs1390532391,2
    --120352725(+) GTGAGC/TAATTA 1 -- ds50010--------
    rs1839072181,2
    --120352751(+) TGCCAC/TGCTAC 1 -- ds50010--------
    rs70978081,2
    C,F,--120352854(+) caaacA/Tcacat 1 -- ds50011Minor allele frequency- T:0.07WA 118
    rs608009251,2
    F,--120352903(+) CTCTTA/CAGTGA 1 -- ds50011Minor allele frequency- C:0.04WA 118
    rs1429654241,2
    --120353036(+) AGGTGC/TTTTTG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for PRLHR (120352916 - 120355160 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for PRLHR: --
    Human Gene Mutation Database (HGMD): PRLHR

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PRLHR
    DNA2.0 Custom Variant and Variant Library Synthesis for PRLHR

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    PRLHR for disorders           About GeneDecksing

    OMIM gene information: 600895    OMIM disorders: --

    9 diseases for PRLHR:    About MalaCards
    rheumatic tricuspid valve disease    pituitary adenoma    adrenocortical tumor    adenoma
    pheochromocytoma    obesity    pertussis    neuroblastoma
    neuronitis

    2 Novoseek disease relationships for PRLHR gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    pituitary adenoma 42.7 4 10984631 (3), 11923475 (1)
    obesity 1.84 3 12716769 (2)

    Genetic Association Database (GAD): PRLHR
    Human Genome Epidemiology (HuGE) Navigator: PRLHR (5 documents)

    Export disorders for PRLHR gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PRLHR gene, integrated from 9 sources (see all 31):
    (articles sorted by number of sources associating them with PRLHR)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and chromosomal mapping of three novel genes, GPR9, GPR10, and GPR14, encoding receptors related to interleukin 8, neuropeptide Y, and somatostatin receptors. (PubMed id 8666380)1, 2, 3 Marchese A.... Docherty J.M. (1995)
    2. Association of polymorphisms in GPR10, the gene encoding the prolactin-releasing peptide receptor with blood pressure, but not obesity, in a U.K. Caucasian population. (PubMed id 12716769)1, 4, 9 Bhattacharyya S....O'Rahilly S. (2003)
    3. The carboxyl terminus of the prolactin-releasing peptide receptor interacts with PDZ domain proteins involved in alpha-amino-3-hydroxy- 5-methylisoxazole-4-propionic acid receptor clustering. (PubMed id 11641419)1, 2, 9 Lin S.H.S.... Civelli O. (2001)
    4. Origin of the prolactin-releasing hormone (PRLH) receptors: evidence of coevolution between PRLH and a redundant neuropeptide Y receptor during vertebrate evolution. (PubMed id 15885496)1, 3, 9 Lagerstrom M.C....Schioth H.B. (2005)
    5. Transcriptional regulation of the human PRL-releasing peptide (PrRP) receptor gene by a dopamine 2 receptor agonist: cloning and characterization of the human PrRP receptor gene and its promoter region. (PubMed id 11923475)1, 2, 9 Ozawa A.... Mori M. (2002)
    6. A prolactin-releasing peptide in the brain. (PubMed id 9607765)1, 2, 9 Hinuma S.... Fujino M. (1998)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    9. Tissue distribution of prolactin-releasing peptide (PrRP) and its receptor. (PubMed id 10498338)1, 2 Fujii R.... Fujino M. (1999)
    10. Characterization of the binding of [(125)I]-human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor. (PubMed id 11030716)1, 9 Langmead C.J....Herdon H.J. (2000)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2834 HGNC: 4464 AceView: GPR10 Ensembl:ENSG00000119973 euGenes: HUgn2834
    ECgene: PRLHR Kegg: 2834 H-InvDB: PRLHR

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PRLHR Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PRLHR gene:
    Search GeneIP for patents involving PRLHR

    GeneCards and IP:
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