External Ids for PRL Gene
Previous GeneCards Identifiers for PRL Gene
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
GeneCards Summary for PRL Gene
PRL (Prolactin) is a Protein Coding gene. Diseases associated with PRL include Impotence and Empty Sella Syndrome. Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Jak-STAT signaling pathway. GO annotations related to this gene include hormone activity and prolactin receptor binding.
UniProtKB/Swiss-Prot for PRL Gene
Prolactin acts primarily on the mammary gland by promoting lactation.