Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



PRKY Gene

pseudogene   GIFtS: 48
GCID: GC0YP007142

Protein Kinase, Y-Linked, Pseudogene

(Previous names: protein kinase, Y-linked)
  Try our

disease database 

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Protein Kinase, Y-Linked, Pseudogene1 2
Protein Kinase, Y-Linked1
PRKXP32
PRKYP2
EC 2.7.11.13
EC 2.7.118

External Ids:    HGNC: 94441   Entrez Gene: 56162   Ensembl: ENSG000000997257   OMIM: 4000085   UniProtKB: O439303   

Export aliases for PRKY gene to outside databases

Previous GC identifers: GC0YP007107 GC0YP006844 GC0YP007185 GC0YP004701


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for PRKY Gene:
This gene is similar to the protein kinase, X-linked gene in the pseudoautosomal region of the X chromosome. The
gene is classified as a transcribed pseudogene because it has lost a coding exon that results in all transcripts
being candidates for nonsense-mediated decay (NMD) and unlikely to express a protein. Abnormal recombination
between this gene and a related gene on chromosome X is a frequent cause of XX males and XY females. (provided by
RefSeq, Jul 2010)

GeneCards Summary for PRKY Gene:
PRKY (protein kinase, Y-linked, pseudogene) is a pseudogene. GO annotations related to this gene include protein serine/threonine kinase activity.

Gene Wiki entry for PRKY Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000024.9  NT_011896.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the PRKY gene promoter:
         RORalpha1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPRKY promoter sequence
   Search Chromatin IP Primers for PRKY

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PRKY


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Yp11.2   Ensembl cytogenetic band:  Yp11.2   HGNC cytogenetic band: Yp11.2

PRKY Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PRKY gene location

GeneLoc information about chromosome Y         GeneLoc Exon Structure

GeneLoc location for GC0YP007142:  view genomic region     (about GC identifiers)

Start:
7,142,013 bp from pter      End:
7,249,589 bp from pter
Size:
107,577 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: PRKY_HUMAN, O43930 (See protein sequence)
Recommended Name: Putative serine/threonine-protein kinase PRKY  
Size: 277 amino acids; 31708 Da
Caution: Could be the product of a pseudogene. Highly similar to PRKX in the pseudoautosomal region of the X
chromosome, the transcripts specific of that gene are potential candidates for nonsense-mediated decay
Secondary accessions: O15348 O15349

Explore the universe of human proteins at neXtProt for PRKY: NX_O43930

Explore proteomics data for PRKY at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for PRKY (O43930) (see all 8)
     GHIKLTD  IKLTDFG  TDFGFAK  LGILIFE 


    See PRKY Protein Expression from SPIRE MOPED, PaxDB, and MaxQB


    PRKY Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for PRKY
    OriGene Protein Over-expression Lysate for PRKY
    OriGene MassSpec for PRKY
    OriGene Custom Protein Services for PRKY
    GenScript Custom Purified and Recombinant Proteins Services for PRKY
    Novus Biologicals PRKY Protein
    Novus Biologicals PRKY Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PRKY

     
    Search eBioscience for Proteins for PRKY 

     
    antibodies-online proteins for PRKY (3 products) 

     
    Search antibodies-online for peptides for PRKY

    PRKY Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for PRKY
    OriGene Custom Antibody Services for PRKY
    Novus Biologicals PRKY Antibodies
    Abcam antibodies for PRKY
    Cloud-Clone Corp. Antibodies for PRKY
    ThermoFisher Antibodies for PRKY
    antibodies-online antibodies for PRKY (16 products) 

    PRKY Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for PRKY
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for PRKY
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for PRKY
    Cloud-Clone Corp. CLIAs for PRKY
    Search eBioscience for ELISAs for PRKY 
    antibodies-online kits for PRKY 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    IUPHAR Guide to PHARMACOLOGY protein family classification: protein kinase, Y-linked, pseudogene
    Protein kinase A (PKA) family

    4 InterPro protein domains:
     IPR002290 Ser/Thr_dual-sp_kinase_dom
     IPR011009 Kinase-like_dom
     IPR008271 Ser/Thr_kinase_AS
     IPR000719 Prot_kinase_dom

    Graphical View of Domain Structure for InterPro Entry O43930

    ProtoNet protein and cluster: O43930

    UniProtKB/Swiss-Prot: PRKY_HUMAN, O43930
    Similarity: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. cAMP subfamily
    Similarity: Contains 1 protein kinase domain


    Find genes that share domains with PRKY           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PRKY_HUMAN, O43930
    Catalytic activity: ATP + a protein = ADP + a phosphoprotein

         Genatlas biochemistry entry for PRKY:
    serine/threonine protein kinase,cAMP dependent,homologous to Drosophila DC2 kinase,involved in ectopic
    recombination with PRKX,leading to XX male

         Enzyme Numbers (IUBMB): EC 2.7.112 EC 2.7.11.11

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004674protein serine/threonine kinase activity IEA--
    GO:0005524ATP binding IEA--
         
    Find genes that share ontologies with PRKY           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for PRKY:
     Decreased substrate adherent c  Increased colony dispersion (i 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for PRKY

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat PRKY using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate PRKY
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for PRKY
    Predesigned siRNA for gene silencing in human, mouse, rat PRKY

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for PRKY

    Clone
    Products:
         
    OriGene clones in human, mouse for PRKY (see all 6)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for PRKY
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PRKY
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRKY
    Addgene plasmids for PRKY 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for PRKY
    Browse ESI BIO Cell Lines and PureStem Progenitors for PRKY 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRKY


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus3

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PRKY
    Interactions:

        Search GeneGlobe Interaction Network for PRKY

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006468protein phosphorylation TAS9154127

    Find genes that share ontologies with PRKY           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PRKY

    3 HMDB Compounds for PRKY    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Cyclic AMPCyclic AMP (see all 19)60-92-4--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for PRKY gene: 
    NM_002760.3  

    Unigene Cluster for PRKY:

    Protein kinase, Y-linked, pseudogene
    Hs.584730  [show with all ESTs]
    Unigene Representative Sequence: NR_028062
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000528056(uc004fre.3) ENST00000533551 ENST00000495163 ENST00000472666
    ENST00000362758
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat PRKY using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate PRKY
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for PRKY
    Predesigned siRNA for gene silencing in human, mouse, rat PRKY
    Clone
    Products:
         
    OriGene clones in human, mouse for PRKY (see all 6)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for PRKY
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PRKY
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRKY
    Addgene plasmids for PRKY 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for PRKY
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat PRKY
      QuantiTect SYBR Green Assays in human, mouse, rat PRKY
      QuantiFast Probe-based Assays in human, mouse, rat PRKY

    Additional mRNA sequence: 

    BC074851.2 BC074852.2 NR_028062.1 Y10484.1 Y10485.1 

    3 DOTS entries:

    DT.95273058  DT.95153312  DT.100018653 

    Selected AceView cDNA sequences (see all 57):

    BQ082031 BX107976 AA602461 AA602302 BC074851 AA490258 AW593234 AA767129 
    BC074852 CB242248 AI929286 CA446672 AI651473 AI417940 BG506561 N34383 
    AW590240 AW976948 BG698237 Y10484 AI929361 W24161 BM838190 Y15801 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    PRKY expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    PRKY Expression
    About this image

    PRKY Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PRKY Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.584730

    UniProtKB/Swiss-Prot: PRKY_HUMAN, O43930
    Tissue specificity: Ubiquitous

        Custom PCR Arrays for PRKY
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for PRKY
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat PRKY
    QuantiTect SYBR Green Assays in human, mouse, rat PRKY
    QuantiFast Probe-based Assays in human, mouse, rat PRKY
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRKY

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for PRKY gene from Selected species (see all 2)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    soybean
    (Glycine max)
    eudicotyledons BQ629829.12   -- 74.77(n)    BQ629829.1 


    ENSEMBL Gene Tree for PRKY (if available)
    TreeFam Gene Tree for PRKY (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for PRKY gene
    Selected SIMAP similar genes for PRKY using alignment to 1 protein entry:     PRKY_HUMAN(see all similar genes):
    PRKX    PRKACA    KIN27    PRKACB    PRKACG    RPS6KA4
    RPS6KA1    PRKG1    PRKG2    RPS6KA3    RPS6KA2    RPS6KA6
    STK32A    AKT3    AKT1    DKFZp781N0293    ROCK1    ROCK2

    Find genes that share paralogs with PRKY           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for PRKY (see all 846)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr Y posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs31099891,2
    C--7141536(-) TCAGCG/CCCCTG 1 -- us2k12Minor allele frequency- C:0.00NA 4
    rs31163241,2
    C--7143650(-) CTCGTA/CCCACA 1 -- int10--------
    rs31163201,2
    C--7143700(+) attctC/Ttcttt 1 -- int1 trp30--------
    rs31099901,2
    C--7145620(-) tattaA/Ctattt 1 -- int10--------
    rs30970771,2
    C--7149682(+) gtgtaG/Ttatta 1 -- int11Minor allele frequency- T:0.00NA 2
    rs133052191,2
    C--7149924(+) gcTTGG/TAGTCT 1 -- int10--------
    rs30970781,2
    C--7151887(+) GGGATC/TTGCAT 1 -- int11Minor allele frequency- T:0.00NA 2
    rs1139922551,2
    C--7153375(+) GCATCC/TAGGGA 1 -- int11Minor allele frequency- T:0.00CSA 1
    rs562025601,2
    C--7155102(+) GTGGGA/GCACCT 1 -- int10--------
    rs30970851,2
    C--7157736(+) AAAACA/GGaaaa 1 -- int1 trp30--------

    HapMap Linkage Disequilibrium report for PRKY (7142013 - 7249589 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for PRKY:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv7473OTHER Inversion18451855

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing PRKY
    DNA2.0 Custom Variant and Variant Library Synthesis for PRKY

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 400008    OMIM disorders: --

    UniProtKB/Swiss-Prot: PRKY_HUMAN, O43930
  • Note=A chromosomal aberration involving PRKY is a cause of sex reversal disorder. Translocation
    t(X;Y)(p22;p11) with PRKX. Chromosomal translocations proximal to PRKY account for about 30% of the cases of sex
    reversal disorder in XX males and XY females


  • Find genes that share disorders with PRKY           About GenesLikeMe

    Genetic Association Database (GAD): PRKY
    Human Genome Epidemiology (HuGE) Navigator: PRKY (1 document)

    Export disorders for PRKY gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for PRKY gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with PRKY)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Abnormal XY interchange between a novel isolated protein kinase gene, PRKY, and its homologue, PRKX, accounts for one third of all (Y+)XX males and (Y-)XY females. (PubMed id 9302280)1, 2, 9 Schiebel K.... Rappold G.A. (Hum. Mol. Genet. 1997)
    2. Perioperative genomic profiles using structure-specific oligonucleotide probes. (PubMed id 19474452)1, 4 Hogan K.J....Domanico M.J. (amp 2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes. (PubMed id 12815422)1, 2 Skaletsky H.... Page D.C. (Nature 2003)
    5. FISH localization of the human Y-homologue of protein kinase PRKX to Yp11.2 and two pseudogenes to 15q26 and Xq12->13. (PubMed id 9154127)1, 2 Schiebel K....Rappold G. (Cytogenet. Cell Genet. 1997)
    6. The human protein kinase gene PKX1 on Xp22.3 displays Xp/Yp homology and is a site of chromosomal instability. (PubMed id 7633447)1, 3 Klink A.... Rappold G. (Hum. Mol. Genet. 1995)
    7. Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (Cell 2012)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. A selective difference between human Y-chromosomal DNA haplotypes. (PubMed id 9889101)1 Jobling M.A....Tyler-Smith C. (Curr. Biol. 1998)
    10. High-resolution fluorescence in situ hybridization of human Y-linked genes on released chromatin. (PubMed id 9088640)1 GlAoser B....Schempp W. (Chromosome Res. 1997)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 5616 HGNC: 9444 AceView: PRKY Ensembl:ENSG00000099725 euGenes: HUgn5616
    ECgene: PRKY H-InvDB: PRKY

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for PRKY Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for PRKY gene:
    Search GeneIP for patents involving PRKY

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for PRKY   OriGene RNAi products in human, mouse, rat for PRKY  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for PRKY  
     OriGene MassSpec for PRKY   OriGene clones in human, mouse for PRKY  
     OriGene qSTAR qPCR primer pairs in human, mouse for PRKY   OriGene Purified Protein for PRKY  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for PRKY   OriGene Custom Protein Services for PRKY  

     
     
     Block miRNA regulation of human, mouse, rat PRKY using miScript Target Protectors SeqTarget long-range PCR primers for resequencing PRKY
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PRKY Predesigned siRNA for gene silencing in human, mouse, rat PRKY
     QuantiFast Probe-based Assays in human, mouse, rat PRKY QuantiTect SYBR Green Assays in human, mouse, rat PRKY
     Custom PCR Arrays for PRKY Search Chromatin IP Primers for PRKY
     Pre-validated RT2 qPCR Primer Assay in human, mouse / rat PRKY  Search GeneGlobe Interaction Network for PRKY
     Regulatory tfbs in PRKY promoter
     GenScript Custom Purified and Recombinant Proteins Services for PRKY GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for PRKY
     GenScript Custom Assay Services for PRKY GenScript Custom overexpressing Cell Line Services for PRKY
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for PRKY
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     PRKY antibodies
     PRKY proteins
     PRKY lysates
     Antibodies for PRKY
     See all of Abcam's Antibodies, Kits and Proteins for PRKY
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for PRKY
     Antibodies for PRKY
     ELISAs for PRKY
     CLIAs for PRKY



     Browse ESI BIO Cell Lines and PureStem Progenitors for PRKY
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRKY
     Browse SwitchGear 3'UTR luciferase reporter plasmids for PRKY
     SwitchGear Promoter luciferase reporter plasmids for PRKY
     ThermoFisher Antibodies for PRKY
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRKY
     Browse compounds at ApexBio
     Addgene plasmids for PRKY
      Search eBioscience for proteins for PRKY
      Search eBioscience for elisas for PRKY
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for PRKY
     antibodies-online antibodies for PRKY (16 products)
     antibodies-online kits for PRKY
      Search antibodies-online for peptides for PRKY
     antibodies-online proteins for PRKY (3 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      PRKY gene at Home site.
    Version: 3.12.252 27 Nov 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4