Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



PRKRIP1 Gene

protein-coding   GIFtS: 44
GCID: GC07P102008

PRKR Interacting Protein 1 (IL11 Inducible)

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
PRKR Interacting Protein 1 (IL11 Inducible)1 2
KRAB Box Domain Containing 31 2
Likely Ortholog Of Mouse C114 DsRNA-Binding Protein1 2
C1142
KRBOX32
PRKR-Interacting Protein 12

External Ids:    HGNC: 218941   Entrez Gene: 797062   Ensembl: ENSG000001285637   UniProtKB: Q9H8753   

Export aliases for PRKRIP1 gene to outside databases

Previous GC identifers: GC07P101523 GC07P101597 GC07P101791 GC07P101823 GC07P102006 GC07P096627


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for PRKRIP1 Gene:
PRKRIP1 (PRKR interacting protein 1 (IL11 inducible)) is a protein-coding gene. Diseases associated with PRKRIP1 include malaria. GO annotations related to this gene include protein kinase inhibitor activity and protein kinase binding.

UniProtKB/Swiss-Prot: PKRI1_HUMAN, Q9H875
Function: Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Regulatory transcription factor binding sites in the PRKRIP1 gene promoter:
         Max1   ISGF-3   FOXF2   Pax-5   MZF-1   AREB6   FOXO1a   ZIC2/Zic2   c-Myc   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPRKRIP1 promoter sequence
   Search Chromatin IP Primers for PRKRIP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PRKRIP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22.1   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22.1

PRKRIP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PRKRIP1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P102008:  view genomic region     (about GC identifiers)

Start:
102,004,319 bp from pter      End:
102,067,129 bp from pter
Size:
62,811 bases      Orientation:
plus strand

2 alternative locations:
Chr7+,CRA_TCAG 101,397,108-101,427,419      Chr7+,NW_003571037 320,687-351,012     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: PKRI1_HUMAN, Q9H875 (See protein sequence)
Recommended Name: PRKR-interacting protein 1  
Size: 184 amino acids; 20997 Da
Subunit: Interacts with EIF2AK2 (By similarity)
Secondary accessions: Q8NDM6 Q96CF8

Explore the universe of human proteins at neXtProt for PRKRIP1: NX_Q9H875

Explore proteomics data for PRKRIP1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See PRKRIP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_078929.1  
    ENSEMBL proteins: 
     ENSP00000419270   ENSP00000420136   ENSP00000381010   ENSP00000346837  

    PRKRIP1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for PRKRIP1
    OriGene Protein Over-expression Lysate for PRKRIP1
    OriGene Custom MassSpec
    OriGene Custom Protein Services for PRKRIP1
    GenScript Custom Purified and Recombinant Proteins Services for PRKRIP1
    Novus Biologicals PRKRIP1 Protein
    Novus Biologicals PRKRIP1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PRKRIP1

    PRKRIP1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for PRKRIP1
    Novus Biologicals PRKRIP1 Antibodies
    Abcam antibodies for PRKRIP1
    Cloud-Clone Corp. Antibodies for PRKRIP1
    Search ThermoFisher Antibodies for PRKRIP1
    LSBio Antibodies in human, mouse, rat for PRKRIP1

    PRKRIP1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for PRKRIP1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for PRKRIP1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for PRKRIP1
    Cloud-Clone Corp. CLIAs for PRKRIP1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    ZNF: Zinc fingers, C2H2-type

    1 InterPro protein domain:
     IPR009548 DUF1168

    Graphical View of Domain Structure for InterPro Entry Q9H875

    ProtoNet protein and cluster: Q9H875

    UniProtKB/Swiss-Prot: PKRI1_HUMAN, Q9H875
    Similarity: Belongs to the PRKRIP1 family


    PRKRIP1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PKRI1_HUMAN, Q9H875
    Function: Binds double-stranded RNA. Inhibits EIF2AK2 kinase activity (By similarity)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003725double-stranded RNA binding ISS--
    GO:0004860protein kinase inhibitor activity ISS--
    GO:0005515protein binding ----
    GO:0019901protein kinase binding ISS--
         
    PRKRIP1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for PRKRIP1:
     Actin fiber cells 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PRKRIP1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PRKRIP1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PRKRIP1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PRKRIP1

    miRNA
    Products:
        
    miRTarBase miRNAs that target PRKRIP1:
    hsa-mir-1229-3p (MIRT036381)

    Block miRNA regulation of human, mouse, rat PRKRIP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PRKRIP1 (see all 9):
    hsa-miR-607 hsa-miR-516b* hsa-miR-548o hsa-miR-373* hsa-miR-1323 hsa-miR-516a-3p hsa-miR-24 hsa-miR-616*
    SwitchGear 3'UTR luciferase reporter plasmidPRKRIP1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for PRKRIP1
    Predesigned siRNA for gene silencing in human, mouse, rat PRKRIP1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for PRKRIP1

    Clone
    Products:
         
    OriGene clones in human, mouse for PRKRIP1 (see all 6)
    OriGene ORF clones in mouse, rat for PRKRIP1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PRKRIP1 (NM_024653)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PRKRIP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRKRIP1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for PRKRIP1
    Browse ESI BIO Cell Lines and PureStem Progenitors for PRKRIP1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRKRIP1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    PKRI1_HUMAN, Q9H875: Nucleus, nucleolus (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytoskeleton1
    cytosol1
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus ISS--
    GO:0070062extracellular vesicular exosome IDA19056867

    PRKRIP1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PRKRIP1
    Interactions:

        Search GeneGlobe Interaction Network for PRKRIP1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for PRKRIP1 (Q9H8752, 3 ENSP000003810104) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAGEA11P433642, 3, ENSP000003473584MINT-66518 I2D: score=4 STRING: ENSP00000347358
    EIF2AK2P195253, ENSP000002330574I2D: score=2 STRING: ENSP00000233057
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003014renal system process IDA--
    GO:0006469negative regulation of protein kinase activity ISS--
    GO:0042326negative regulation of phosphorylation ISS--

    PRKRIP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PRKRIP1 (PKRI1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for PRKRIP1 gene: 
    NM_024653.3  

    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000477886 ENST00000469763(uc022ajf.1) ENST00000482549 ENST00000496391(uc003uze.2 uc003uzd.1 uc011kkq.1 uc003uzh.2 uc011kkr.1)
    ENST00000482465 ENST00000462601 ENST00000397912 ENST00000468316 ENST00000354783

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat PRKRIP1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate PRKRIP1 (see all 9):
    hsa-miR-607 hsa-miR-516b* hsa-miR-548o hsa-miR-373* hsa-miR-1323 hsa-miR-516a-3p hsa-miR-24 hsa-miR-616*
    SwitchGear 3'UTR luciferase reporter plasmidPRKRIP1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for PRKRIP1
    Predesigned siRNA for gene silencing in human, mouse, rat PRKRIP1
    Clone
    Products:
         
    OriGene clones in human, mouse for PRKRIP1 (see all 6)
    OriGene ORF clones in mouse, rat for PRKRIP1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PRKRIP1 (NM_024653)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PRKRIP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRKRIP1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for PRKRIP1
    OriGene qSTAR qPCR primer pairs in human, mouse for PRKRIP1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PRKRIP1
      QuantiTect SYBR Green Assays in human, mouse, rat PRKRIP1
      QuantiFast Probe-based Assays in human, mouse, rat PRKRIP1

    Selected AceView cDNA sequences (see all 334):

    AL560771 BP357860 AL833837 BI007726 BI006345 AW197305 BQ327676 BI006358 
    BM561231 BQ055887 AI674519 BI007716 BQ056479 BQ643286 BI006359 BF823561 
    BF823554 CR602187 BF823562 BI006360 BM767860 AI299332 BI834951 BI006903 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for PRKRIP1    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b
    SP1:                                      -                                                                     
    SP2:                                                                                            -               
    SP3:                                                                                                            
    SP4:                                                                                                            
    SP5:                                                                                -           -               


    ECgene alternative splicing isoforms for PRKRIP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    PRKRIP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCTGGCTGT
    PRKRIP1 Expression
    About this image

    PRKRIP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PRKRIP1 Protein Expression
        Custom PCR Arrays for PRKRIP1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for PRKRIP1
    OriGene qSTAR qPCR primer pairs in human, mouse for PRKRIP1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PRKRIP1
    QuantiTect SYBR Green Assays in human, mouse, rat PRKRIP1
    QuantiFast Probe-based Assays in human, mouse, rat PRKRIP1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRKRIP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for PRKRIP1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Prkrip11 , 5 Prkr interacting protein 1 (IL11 inducible)1, 5 90.22(n)1
    92.39(a)1
      5 (75.88 cM)5
    668011  NM_025774.31  NP_080050.11 
     1361781275 
    chicken
    (Gallus gallus)
    Aves PRKRIP11 PRKR interacting protein 1 (IL11 inducible) 71.79(n)
    75.82(a)
      417508  NM_001006214.2  NP_001006214.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.237532 Xenopus laevis transcribed sequence with weak similarity more 73.56(n)    CF282792.1 
    zebrafish
    (Danio rerio)
    Actinopterygii neurog32 neurogenin 3 76.3(n)    AL919094.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG84416
    --
    29(a)
    1 ↔ 1
    2R(12072627-12074011)
    worm
    (Caenorhabditis elegans)
    Secernentea F37A4.26
    Protein F37A4.2 (F37A4.2) mRNA, complete cds
    34(a)
    1 ↔ 1
    III(6722498-6723285) WBGene00018132


    ENSEMBL Gene Tree for PRKRIP1 (if available)
    TreeFam Gene Tree for PRKRIP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for PRKRIP1 (see all 703)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs568990111,2
    C--102036010(+) AAAAAAA/-GTTAT 1 -- int11Minor allele frequency- -:0.00NA 2
    rs1118928261,2
    F--102039505(+) TTGAGA/GCTCCA 1 -- int13Minor allele frequency- G:0.33CSA 6
    rs39880901,2
    C,F,H--102049021(+) AAAGGA/C/GCAAGG 1 -- int110NS EA NA WA 838
    rs114551421,2
    C--102057131(+) TTTTTT/-GGAGA 1 -- int11Minor allele frequency- -:0.00NA 2
    rs1812056571,2
    --105395643(+) GGCACA/GATCTT 1 -- us2k10--------
    rs1860118141,2
    --105395697(+) GTCTCA/GGCCTC 1 -- us2k10--------
    rs1905507771,2
    --105395715(+) GCTGGA/GATTAC 1 -- us2k10--------
    rs1827750891,2
    --105395768(+) AGAGAC/TGGGGT 1 -- us2k10--------
    rs1444357871,2
    --105395902(+) TCAACG/TAAACA 1 -- us2k10--------
    rs1394078301,2
    --105395969(+) TAACCA/GGGGAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PRKRIP1 (102004319 - 102067129 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for PRKRIP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv464665CNV Loss19166990
    nsv831083CNV Loss17160897
    nsv464664CNV Gain19166990
    nsv428182CNV Gain18775914
    dgv2121e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PRKRIP1
    DNA2.0 Custom Variant and Variant Library Synthesis for PRKRIP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    1 disease for PRKRIP1:    
    About MalaCards
    malaria


    PRKRIP1 for disorders           About GeneDecksing


    Export disorders for PRKRIP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for PRKRIP1 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with PRKRIP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    2. C114 is a novel IL-11-inducible nuclear double-stranded RNA-binding protein that inhibits protein kinase R. (PubMed id 12679338)1, 3 Yin Z....Yang Y.C. (J. Biol. Chem. 2003)
    3. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    5. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PubMed id 19056867)1 Gonzales P.A....Knepper M.A. (J. Am. Soc. Nephrol. 2009)
    6. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    7. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)2 Olsen J.V....Mann M. (Cell 2006)
    8. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    9. Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (Nature 2005)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 79706 HGNC: 21894 AceView: PRKRIP1 Ensembl:ENSG00000128563 euGenes: HUgn79706
    ECgene: PRKRIP1 H-InvDB: PRKRIP1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for PRKRIP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for PRKRIP1 gene:
    Search GeneIP for patents involving PRKRIP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for PRKRIP1  
     OriGene qPCR primer pairs and template standards for PRKRIP1   OriGene Protein Over-expression Lysate for PRKRIP1  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for PRKRIP1  
     OriGene qSTAR qPCR primer pairs in human, mouse for PRKRIP1   OriGene Purified Protein for PRKRIP1  
     OriGene ORF clones in mouse, rat for PRKRIP1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for PRKRIP1   OriGene Custom Protein Services for PRKRIP1  

     
     
     Block miRNA regulation of human, mouse, rat PRKRIP1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing PRKRIP1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PRKRIP1 Predesigned siRNA for gene silencing in human, mouse, rat PRKRIP1
     QuantiFast Probe-based Assays in human, mouse, rat PRKRIP1 QuantiTect SYBR Green Assays in human, mouse, rat PRKRIP1
     Custom PCR Arrays for PRKRIP1 Search Chromatin IP Primers for PRKRIP1
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PRKRIP1  Search GeneGlobe Interaction Network for PRKRIP1
     Regulatory tfbs in PRKRIP1 promoter
     GenScript Custom Purified and Recombinant Proteins Services for PRKRIP1 GenScript cDNA clones with any tag delivered in your preferred vector for PRKRIP1
     GenScript Custom Assay Services for PRKRIP1 GenScript Custom overexpressing Cell Line Services for PRKRIP1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for PRKRIP1 (PKRI1)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     PRKRIP1 antibodies
     PRKRIP1 proteins
     PRKRIP1 lysates
     Antibodies for PRKRIP1
     See all of Abcam's Antibodies, Kits and Proteins for PRKRIP1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for PRKRIP1
     Antibodies for PRKRIP1
     ELISAs for PRKRIP1
     CLIAs for PRKRIP1



     Browse ESI BIO Cell Lines and PureStem Progenitors for PRKRIP1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRKRIP1
     SwitchGear 3'UTR luciferase reporter plasmids for PRKRIP1
     SwitchGear Promoter luciferase reporter plasmids for PRKRIP1
     Search ThermoFisher Antibodies for PRKRIP1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRKRIP1
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PRKRIP1
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PRKRIP1
     LSBio Antibodies in human, mouse, rat for PRKRIP1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      PRKRIP1 gene at Home site.
    Version: 3.12.142 28 July 2014
    hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4