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PRKCDBP Gene

protein-coding   GIFtS: 56
GCID: GC11M006340

Protein Kinase C, Delta Binding Protein

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Protein Kinase C, Delta Binding Protein1 2     HSRBC2
Sdr-Related Gene Product That Binds To C-Kinase1 2     cavin-32
Serum Deprivation Response Factor-Related Gene Product That Binds To
C-Kinase2 3
     Protein Kinase C Delta-Binding Protein2
SRBC2 3     Cavin-33
CAVIN32     hSRBC3

External Ids:    HGNC: 94001   Entrez Gene: 1124642   Ensembl: ENSG000001709557   UniProtKB: Q969G53   
ORGUL members:         

Export aliases for PRKCDBP gene to outside databases

Previous GC identifers: GC11M007083 GC11M006800 GC11M006299 GC11M006304 GC11M006296 GC11M006000


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for PRKCDBP Gene:
The protein encoded by this gene was identified as a binding protein of the protein kinase C, delta (PRKCD). The
expression of this gene in cultured cell lines is strongly induced by serum starvation. The expression of this
protein was found to be down-regulated in various cancer cell lines, suggesting the possible tumor suppressor
function of this protein. (provided by RefSeq, Jul 2008)

GeneCards Summary for PRKCDBP Gene:
PRKCDBP (protein kinase C, delta binding protein) is a protein-coding gene. Diseases associated with PRKCDBP include lung cancer, and ovarian cancer. GO annotations related to this gene include protein kinase C binding. An important paralog of this gene is PTRF.

UniProtKB/Swiss-Prot: PRDBP_HUMAN, Q969G5
Function: Seems to have an immune potentiation function (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000011.10  NC_018922.2  NT_009237.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the PRKCDBP gene promoter:
         RFX1   Spz1   Brachyury   Lmo2   CUTL1   Max   Egr-2   GCNF-2   c-Myc   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPRKCDBP promoter sequence
   Search Chromatin IP Primers for PRKCDBP

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PRKCDBP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11p15.4   Ensembl cytogenetic band:  11p15.4   HGNC cytogenetic band: 11p15.4

PRKCDBP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PRKCDBP gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M006340:  view genomic region     (about GC identifiers)

Start:
6,340,176 bp from pter      End:
6,341,877 bp from pter
Size:
1,702 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: PRDBP_HUMAN, Q969G5 (See protein sequence)
Recommended Name: Protein kinase C delta-binding protein  
Size: 261 amino acids; 27701 Da
Subunit: Interacts with PRKCD and with phosphatidylserine. Phosphatidylserine may form a bridge between PKC and
PKC-binding partners and stabilize the binding (By similarity)

Explore the universe of human proteins at neXtProt for PRKCDBP: NX_Q969G5

Explore proteomics data for PRKCDBP at MOPED

Post-translational modifications: 

  • In vitro, phosphorylated by PRKCD1
  • Ubiquitination2 at Lys84
  • Modification sites at PhosphoSitePlus

  • See PRKCDBP Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_659477.2  
    ENSEMBL proteins: 
     ENSP00000307292   ENSP00000432047  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026752 Cavin_fam

    Graphical View of Domain Structure for InterPro Entry Q969G5

    ProtoNet protein and cluster: Q969G5

    UniProtKB/Swiss-Prot: PRDBP_HUMAN, Q969G5
    Similarity: Belongs to the PTRF/SDPR family


    PRKCDBP for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PRDBP_HUMAN, Q969G5
    Function: Seems to have an immune potentiation function (By similarity)
    Induction: Down-regulated in breast and lung cancer cell lines

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005080protein kinase C binding IEA--
    GO:0005515protein binding IPI19262564
         
    PRKCDBP for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for PRKCDBP:
     Decreased TP53 protein express 

         7 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Prkcdbp):
     adipose tissue  cardiovascular system  cellular  growth/size/body  liver/biliary system 
     mortality/aging  respiratory system 

    PRKCDBP for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for PRKCDBP: Prkcdbptm1(KOMP)Vlcg Prkcdbptm1Pemi

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PRKCDBP
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PRKCDBP

    miRNA
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    miRTarBase miRNAs that target PRKCDBP:
    hsa-mir-30a-5p (MIRT028649), hsa-mir-124-3p (MIRT023033)

    Block miRNA regulation of human, mouse, rat PRKCDBP using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate PRKCDBP:
    hsa-miR-3122 hsa-miR-3913-5p
    SwitchGear 3'UTR luciferase reporter plasmidPRKCDBP 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular2
    nucleus2
    cytosol1
    mitochondrion1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for PRKCDBP About    
    See pathways by source

    SuperPathContained pathways About
    1ADP signalling through P2Y purinoceptor 12
    Beta-agonist/Beta-blocker Pathway, Pharmacodynamics0.34


    1 PharmGKB Pathway for PRKCDBP
        Beta-agonist/Beta-blocker Pathway, Pharmacodynamics

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PRKCDBP
    Interactions:

        Search GeneGlobe Interaction Network for PRKCDBP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 6)

    Selected Interacting proteins for PRKCDBP (Q969G51, 2, 3 ENSP000003072924) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EPS15L1Q9UBC21, 2, 3, ENSP000002480704EBI-3893101,EBI-2556746 MINT-7234785 MINT-7234809 I2D: score=1 STRING: ENSP00000248070
    CAV1Q031352, 3, ENSP000003391914MINT-7234685 MINT-7234785 MINT-7234696 MINT-7234742 I2D: score=1 STRING: ENSP00000339191
    CAV3P565392, 3, ENSP000003419404MINT-7234765 I2D: score=1 STRING: ENSP00000341940
    SDPRO958102, 3, ENSP000003056754MINT-7234727 I2D: score=1 STRING: ENSP00000305675
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PRKCDBP (PRDBP)

    Selected HMDB Compounds for PRKCDBP (see all 124)    About this table
    CompoundSynonyms CAS #PubMed Ids
    PS(14:0/14:0)Phosphatidylserine(14:0/14:0) (see all 7)----
    PS(14:0/14:1(9Z))Phosphatidylserine(14:0/14:1n5) (see all 13)----
    PS(14:0/16:0)1-myristoyl-2-palmitoyl-sn-glycero-3-phosphoserine (see all 7)----
    PS(14:0/16:1(9Z))PS(14:0/16:1n7) (see all 13)----
    PS(14:0/18:0)Phosphatidylserine(32:0) (see all 7)----
    PS(14:0/18:1(9Z))PSer(14:0/18:1n9) (see all 13)----
    PS(14:0/18:2(9Z,12Z))PS(14:0/18:2) (see all 13)----
    PS(14:0/18:3(9Z,12Z,15Z))Phosphatidylserine(14:0/18:3) (see all 14)----
    PS(14:0/20:3(8Z,11Z,14Z))PSer(14:0/20:3) (see all 14)----
    PS(14:0/20:4(5Z,8Z,11Z,14Z))PS(34:4) (see all 13)----



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for PRKCDBP gene: 
    NM_145040.2  

    Unigene Cluster for PRKCDBP:

    Protein kinase C, delta binding protein
    Hs.434044  [show with all ESTs]
    Unigene Representative Sequence: BQ073453
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000532354 ENST00000303927(uc001mcu.1) ENST00000524852 ENST00000530979

    miRNA
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    2 qRT-PCR Assays for microRNAs that regulate PRKCDBP:
    hsa-miR-3122 hsa-miR-3913-5p
    SwitchGear 3'UTR luciferase reporter plasmidPRKCDBP 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat PRKCDBP
      QuantiFast Probe-based Assays in human, mouse, rat PRKCDBP

    Additional mRNA sequence: 

    AF339881.1 BC011585.1 BC038387.1 

    8 DOTS entries:

    DT.455134  DT.100821759  DT.100821758  DT.91750401  DT.100821760  DT.91750400  DT.97844916  DT.100886896 

    Selected AceView cDNA sequences (see all 237):

    BX360588 AI472340 CR598951 BC011585 CR620659 BQ017596 BU161220 CB960296 
    BU728935 BQ949362 BQ671687 AI741986 BM128336 BG477696 CD671133 BM723840 
    BG764417 BG476603 BM449659 BX335218 BI964111 BM894268 BI825679 BE729505 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for PRKCDBP    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c · 3d
    SP1:                                                            
    SP2:                          -     -                           
    SP3:                          -     -                           
    SP4:                          -                                 


    ECgene alternative splicing isoforms for PRKCDBP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PRKCDBP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTGGAGACTC
    PRKCDBP Expression
    About this image


    PRKCDBP expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Heart (Cardiovascular System)    fully expand to see all 2 entries
             Atrioventricular Canal Cells Atrioventricular Canal
             Outflow Tract
     
     Adipose (Muscoskeletal System)
             Visceral White Adipose
     
     Neurons
             GABAergic Amacrine Cells Inner Nuclear Layer
     
     Eye (Sensory Organs)
             GABAergic Amacrine Cells Inner Nuclear Layer
    PRKCDBP Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PRKCDBP Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.434044

    UniProtKB/Swiss-Prot: PRDBP_HUMAN, Q969G5
    Tissue specificity: Strongly expressed in mammary and epithelial cells

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRKCDBP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for PRKCDBP gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Prkcdbp1 , 5 protein kinase C, delta binding protein1, 5 82.94(n)1
    83.33(a)1
      7 (55.87 cM)5
    1090421  NM_028444.11  NP_082720.11 
     1054806165 
    chicken
    (Gallus gallus)
    Aves PRKCDBP6
    protein kinase C, delta binding protein
    25(a)
    1 ↔ 1
    7(7694859-7704115) ENSGALG00000028174
    lizard
    (Anolis carolinensis)
    Reptilia PRKCDBP6
    protein kinase C, delta binding protein
    21(a)
    1 ↔ 1
    2(133678899-133724475)
    zebrafish
    (Danio rerio)
    Actinopterygii sdprb6
    sdpra6
    serum deprivation response a
    19(a)
    17(a)
    many ↔ many
    many ↔ many
    6(9059433-9088387) ENSDARG00000071196
    9(25256413-25275937) ENSDARG00000027611


    ENSEMBL Gene Tree for PRKCDBP (if available)
    TreeFam Gene Tree for PRKCDBP (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PRKCDBP gene
    PTRF2  SDPR2  MURC2  
    2 SIMAP similar genes for PRKCDBP using alignment to 2 protein entries:     PRDBP_HUMAN (see all proteins):
    PTRF    SDPR

    PRKCDBP for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PRKCDBP (see all 155)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1873095501,2
    --6339713(+) TCAACA/TGTGGC 1 -- ds50010--------
    rs733969641,2
    C,F--6339821(+) AATCCT/AGGAAA 1 -- ds50011Minor allele frequency- A:0.50WA 2
    rs719983131,2
    C--6339933(+) AAAAA-/AAAC  
     
    /AAACAC
    ACACA
    2 -- ds5001 cds10--------
    rs49887451,2
    C,F--6339934(+) AAAAAC/AACACA 1 -- ds50013Minor allele frequency- A:0.25NA 8
    rs728940681,2
    C--6339936(+) AAAAAA/CACACA 1 -- ds50010--------
    rs558119211,2
    C--6339944(+) CACAC-/TCACACT 1 -- ds50010--------
    rs49887471,2
    C--6339949(+) CACACA/TCACAC 1 -- ds50011Minor allele frequency- T:0.00NA 2
    rs49887481,2
    C--6339950(+) ACACTA/CACACA 1 -- ds50011Minor allele frequency- C:0.00NA 2
    rs49887491,2
    C--6339952(+) ACTCAA/CACAAA 1 -- ds50011Minor allele frequency- C:0.00NA 2
    rs49887501,2
    C,F--6339957(+) CACAAC/AAACAA 1 -- ds50013Minor allele frequency- A:0.25NA 8

    HapMap Linkage Disequilibrium report for PRKCDBP (6340176 - 6341877 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for PRKCDBP:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv519454CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PRKCDBP
    DNA2.0 Custom Variant and Variant Library Synthesis for PRKCDBP

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    6 diseases for PRKCDBP:    
    About MalaCards
    lung cancer    ovarian cancer    lymphoblastic leukemia    colorectal cancer
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    PRKCDBP for disorders           About GeneDecksing

    Genetic Association Database (GAD): PRKCDBP
    Human Genome Epidemiology (HuGE) Navigator: PRKCDBP (5 documents)

    Export disorders for PRKCDBP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PRKCDBP gene, integrated from 10 sources (see all 31):
    (articles sorted by number of sources associating them with PRKCDBP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Inactivation of human SRBC, located within the 11p15.5-p15.4 tumor suppressor region, in breast and lung cancers. (PubMed id 11691816)1, 2, 9 Xu X.L....Minna J.D. (Cancer Res. 2001)
    2. A protein kinase Cdelta-binding protein SRBC whose expression is induced by serum starvation. (PubMed id 9054438)1, 3, 9 Izumi Y....Ohno S. (J. Biol. Chem. 1997)
    3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    4. Multi-ethnic genetic association study of carotid intima-media thickness using a targeted cardiovascular SNP microarray. (PubMed id 19679847)1, 4 Lanktree M.B....Anand S.S. ( a journal of cerebral circulation 2009)
    5. Expression of the candidate tumor suppressor gene hSRBC is frequently lost in primary lung cancers with and without DNA methylation. (PubMed id 15940253)1, 9 ZAPchbauer-MA1ller S....Minna J.D. (Oncogene 2005)
    6. Frequent inactivation of hSRBC in ovarian cancers by promoter CpG island hypermethylation. (PubMed id 20423276)1, 9 Tong S.Y....Lee S.K. (Acta Obstet Gynecol Scand 2010)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    8. Clinical relevance of loss of 11p15 in primary and metastatic breast cancer: association with loss of PRKCDBP expression in brain metastases. (PubMed id 23118876)1 Wikman H....Pantel K. (PLoS ONE 2012)
    9. Genetic polymorphism of PRKCDBP is associated with an increased risk of endometrial cancer. (PubMed id 23020606)1 Tong S.Y....Lee S.K. (Cancer Invest. 2012)
    10. Down-regulation of the cavin family proteins in breast cancer. (PubMed id 21913217)1 Bai L....Cong Y.S. (J. Cell. Biochem. 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 112464 HGNC: 9400 AceView: PRKCDBP Ensembl:ENSG00000170955 euGenes: HUgn112464
    ECgene: PRKCDBP H-InvDB: PRKCDBP

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PRKCDBP Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for PRKCDBP Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PRKCDBP gene:
    Search GeneIP for patents involving PRKCDBP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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