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Aliases for PRKAG1 Gene

Aliases for PRKAG1 Gene

  • Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 1 2 3 5
  • Protein Kinase, AMP-Activated, Gamma 1 Non-Catalytic Subunit 2 3
  • AMPK Gamma1 3 4
  • AMPKG 3 4
  • 5-AMP-Activated Protein Kinase, Gamma-1 Subunit 3
  • 5-AMP-Activated Protein Kinase Subunit Gamma-1 3
  • AMPK Subunit Gamma-1 4
  • AMPK Gamma-1 Chain 3

External Ids for PRKAG1 Gene

Previous GeneCards Identifiers for PRKAG1 Gene

  • GC12P049402
  • GC12M049112
  • GC12M047682
  • GC12M049396
  • GC12M046427

Summaries for PRKAG1 Gene

Entrez Gene Summary for PRKAG1 Gene

  • The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

GeneCards Summary for PRKAG1 Gene

PRKAG1 (Protein Kinase AMP-Activated Non-Catalytic Subunit Gamma 1) is a Protein Coding gene. Diseases associated with PRKAG1 include Ascariasis. Among its related pathways are RET signaling and Regulation of TP53 Activity. GO annotations related to this gene include protein kinase activity and ADP binding. An important paralog of this gene is PRKAG2.

UniProtKB/Swiss-Prot for PRKAG1 Gene

  • AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.

Gene Wiki entry for PRKAG1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRKAG1 Gene

Genomics for PRKAG1 Gene

Regulatory Elements for PRKAG1 Gene

Enhancers for PRKAG1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12G048850 1.2 ENCODE 10.4 +167.1 167069 3.3 CREB3L1 YBX1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 SP3 NFYC TBX21 DDX23 CCNT1 SENP1 KANSL2 LOC390314 CACNB3 PRKAG1 PRPF40B CCDC65 LOC105369755
GH12G048104 1.2 ENCODE 10.3 +912.9 912908 4.1 CREB3L1 AGO1 ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF263 SP3 RPL37P19 CACNB3 CCDC184 ZNF641 H1FNT OR5BK1P ADCY6 ARF3 RNU6-1203P PRKAG1
GH12G049676 0.9 dbSUPER 10.3 -657.9 -657944 0.6 HDAC1 YBX3 HDGF CBX3 ZNF48 ZBTB40 RAD21 ZNF143 ETV6 RELB ASIC1 FAIM2 FMNL3 TMBIM6 CACNB3 BCDIN3D-AS1 CERS5 PRKAG1 TUBA1A ENSG00000272368
GH12G049129 1.5 ENCODE dbSUPER 4.9 -112.2 -112170 4.6 MLX CREB3L1 AGO1 DMAP1 YBX1 FEZF1 YY1 SLC30A9 ZNF416 ZNF143 DDX23 LOC390314 CCNT1 KANSL2 PRPF40B LOC105369760 BCDIN3D OR5BK1P CCDC184 LOC100422296
GH12G049017 1.1 ENCODE 0.7 +0.2 176 4.0 HDGF PKNOX1 MLX CREB3L1 ARNT AGO1 WRNIP1 ARID4B SIN3A DMAP1 DDN DDX23 CCNT1 LOC390314 CACNB3 PRPF40B SENP1 PRKAG1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around PRKAG1 on UCSC Golden Path with GeneCards custom track

Promoters for PRKAG1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000051564 380 1601 PKNOX1 MLX CREB3L1 ARNT AGO1 WRNIP1 ARID4B SIN3A DMAP1 ZNF2

Genomic Location for PRKAG1 Gene

Chromosome:
12
Start:
49,002,272 bp from pter
End:
49,019,197 bp from pter
Size:
16,926 bases
Orientation:
Minus strand

Genomic View for PRKAG1 Gene

Genes around PRKAG1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRKAG1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRKAG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRKAG1 Gene

Proteins for PRKAG1 Gene

  • Protein details for PRKAG1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P54619-AAKG1_HUMAN
    Recommended name:
    5-AMP-activated protein kinase subunit gamma-1
    Protein Accession:
    P54619
    Secondary Accessions:
    • B4DDT7
    • Q8N7V9

    Protein attributes for PRKAG1 Gene

    Size:
    331 amino acids
    Molecular mass:
    37579 Da
    Quaternary structure:
    • AMPK is a heterotrimer of an alpha catalytic subunit (PRKAA1 or PRKAA2), a beta (PRKAB1 or PRKAB2) and a gamma non-catalytic subunits (PRKAG1, PRKAG2 or PRKAG3). Interacts with FNIP1 and FNIP2.

    Three dimensional structures from OCA and Proteopedia for PRKAG1 Gene

    Alternative splice isoforms for PRKAG1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PRKAG1 Gene

Post-translational modifications for PRKAG1 Gene

  • Phosphorylated by ULK1 and ULK2; leading to negatively regulate AMPK activity and suggesting the existence of a regulatory feedback loop between ULK1, ULK2 and AMPK.
  • Ubiquitination at posLast=170170
  • Modification sites at PhosphoSitePlus

Antibody Products

  • Cell Signaling Technology (CST) Antibodies for PRKAG1 (AMPKG1)
  • Cloud-Clone Corp. Antibodies for PRKAG1

No data available for DME Specific Peptides for PRKAG1 Gene

Domains & Families for PRKAG1 Gene

Protein Domains for PRKAG1 Gene

InterPro:
Blocks:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

P54619

UniProtKB/Swiss-Prot:

AAKG1_HUMAN :
  • The AMPK pseudosubstrate motif resembles the sequence around sites phosphorylated on target proteins of AMPK, except the presence of a non-phosphorylatable residue in place of Ser. In the absence of AMP this pseudosubstrate sequence may bind to the active site groove on the alpha subunit (PRKAA1 or PRKAA2), preventing phosphorylation by the upstream activating kinase STK11/LKB1.
  • Belongs to the 5-AMP-activated protein kinase gamma subunit family.
Domain:
  • The AMPK pseudosubstrate motif resembles the sequence around sites phosphorylated on target proteins of AMPK, except the presence of a non-phosphorylatable residue in place of Ser. In the absence of AMP this pseudosubstrate sequence may bind to the active site groove on the alpha subunit (PRKAA1 or PRKAA2), preventing phosphorylation by the upstream activating kinase STK11/LKB1.
  • The 4 CBS domains mediate binding to nucleotides. Of the 4 potential nucleotide-binding sites, 3 are occupied, designated as sites 1, 3, and 4 based on the CBS modules that provide the acidic residue for coordination with the 2- and 3-hydroxyl groups of the ribose of AMP. Of these, site 4 appears to be a structural site that retains a tightly held AMP molecule (AMP 3). The 2 remaining sites, 1 and 3, can bind either AMP, ADP or ATP. Site 1 (AMP, ADP or ATP 1) is the high-affinity binding site and likely accommodates AMP or ADP. Site 3 (AMP, ADP or ATP 2) is the weakest nucleotide-binding site on the gamma subunit, yet it is exquisitely sensitive to changes in nucleotide levels and this allows AMPK to respond rapidly to changes in cellular energy status. Site 3 is likely to be responsible for protection of a conserved threonine in the activation loop of the alpha catalytic subunit through conformational changes induced by binding of AMP or ADP.
Family:
  • Belongs to the 5-AMP-activated protein kinase gamma subunit family.
genes like me logo Genes that share domains with PRKAG1: view

Function for PRKAG1 Gene

Molecular function for PRKAG1 Gene

GENATLAS Biochemistry:
protein kinase,cAMP activated ,gamma 1 non catalytic subunit,complexing with alpha 2 and beta 2 subunits,involved in fatty acid and cholesterol metabolism
UniProtKB/Swiss-Prot Function:
AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.

Gene Ontology (GO) - Molecular Function for PRKAG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004672 protein kinase activity IDA 17028174
GO:0004679 contributes_to AMP-activated protein kinase activity ISS --
GO:0004691 cAMP-dependent protein kinase activity TAS 9598317
GO:0005515 protein binding IPI 16306228
GO:0005524 ATP binding ISS --
genes like me logo Genes that share ontologies with PRKAG1: view
genes like me logo Genes that share phenotypes with PRKAG1: view

Animal Models for PRKAG1 Gene

MGI Knock Outs for PRKAG1:

Animal Model Products

  • Taconic Biosciences Mouse Models for PRKAG1

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for PRKAG1 Gene

Localization for PRKAG1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PRKAG1 gene
Compartment Confidence
extracellular 5
nucleus 5
cytosol 5
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for PRKAG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm TAS --
GO:0005829 cytosol TAS --
GO:0016020 membrane IDA 19946888
GO:0031588 nucleotide-activated protein kinase complex ISS --
genes like me logo Genes that share ontologies with PRKAG1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for PRKAG1 Gene

Pathways & Interactions for PRKAG1 Gene

genes like me logo Genes that share pathways with PRKAG1: view

SIGNOR curated interactions for PRKAG1 Gene

Activates:

Gene Ontology (GO) - Biological Process for PRKAG1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006110 regulation of glycolytic process TAS 8663446
GO:0006468 protein phosphorylation TAS,IDA 17028174
GO:0006629 lipid metabolic process IEA --
GO:0006631 fatty acid metabolic process IEA --
GO:0006633 fatty acid biosynthetic process IEA --
genes like me logo Genes that share ontologies with PRKAG1: view

Drugs & Compounds for PRKAG1 Gene

(15) Drugs for PRKAG1 Gene - From: DrugBank and ApexBio

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Aspirin Approved, Vet_approved Pharma Channel blocker, Target, activator 1152
AICAR Experimental Pharma AMPK activator 0
AICAR phosphate Pharma AMPK activator 0
Dorsomorphin Pharma AMPK inhibitor 0
Dorsomorphin 2HCl Pharma AMPK inhibitor 0

(14) ApexBio Compounds for PRKAG1 Gene

Compound Action Cas Number
AICAR AMPK activator 2627-69-2
AICAR phosphate AMPK activator 681006-28-0
Dorsomorphin AMPK inhibitor 866405-64-3
Dorsomorphin 2HCl AMPK inhibitor 1219168-18-9
GSK621 AMPK agonist 1346607-05-3
Imeglimin Antidiabetic agent 775351-65-0
Imeglimin hydrochloride Antidiabetic agent 775351-61-6
Phenformin HCl 834-28-6
PT 1 AMPK activator, selective 331002-70-1
RSVA 405 140405-36-3
SAMS Peptide 125911-68-4
YLF-466D 1273323-67-3
ZLN024 723249-01-2
ZLN024 hydrochloride
genes like me logo Genes that share compounds with PRKAG1: view

Transcripts for PRKAG1 Gene

Unigene Clusters for PRKAG1 Gene

Protein kinase, AMP-activated, gamma 1 non-catalytic subunit:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PRKAG1 Gene

ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b · 8c ^ 9a · 9b ^ 10 ^ 11a · 11b ^ 12 ^ 13a · 13b ^
SP1: - - - - - - - -
SP2: - - - - - - - - -
SP3: - - - - - - - -
SP4: - - - - - - -
SP5: - - -
SP6: - - - - - - - -
SP7: - -
SP8: - - - - - -
SP9: - - - -
SP10: -
SP11: - - -
SP12: - - - -

ExUns: 14 ^ 15 ^ 16a · 16b
SP1:
SP2:
SP3:
SP4:
SP5: -
SP6:
SP7:
SP8:
SP9:
SP10:
SP11:
SP12:

Relevant External Links for PRKAG1 Gene

GeneLoc Exon Structure for
PRKAG1
ECgene alternative splicing isoforms for
PRKAG1

Expression for PRKAG1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for PRKAG1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for PRKAG1 Gene



Protein tissue co-expression partners for PRKAG1 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of PRKAG1 Gene:

PRKAG1

SOURCE GeneReport for Unigene cluster for PRKAG1 Gene:

Hs.530862

Evidence on tissue expression from TISSUES for PRKAG1 Gene

  • Muscle(4.3)
  • Liver(4.2)
  • Nervous system(3.7)
genes like me logo Genes that share expression patterns with PRKAG1: view

Primer Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for PRKAG1 Gene

Orthologs for PRKAG1 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for PRKAG1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PRKAG1 34 35
  • 99.8 (n)
dog
(Canis familiaris)
Mammalia PRKAG1 34 35
  • 94.02 (n)
cow
(Bos Taurus)
Mammalia PRKAG1 34 35
  • 93.92 (n)
oppossum
(Monodelphis domestica)
Mammalia PRKAG1 35
  • 88 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Prkag1 34
  • 87.98 (n)
mouse
(Mus musculus)
Mammalia Prkag1 34 16 35
  • 87.68 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia PRKAG1 35
  • 74 (a)
OneToOne
chicken
(Gallus gallus)
Aves PRKAG1 34 35
  • 77.94 (n)
lizard
(Anolis carolinensis)
Reptilia PRKAG1 35
  • 86 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia prkag2 34
  • 74.27 (n)
Str.2067 34
African clawed frog
(Xenopus laevis)
Amphibia Xl.7123 34
zebrafish
(Danio rerio)
Actinopterygii prkag1 34 35
  • 73.29 (n)
wufa94d09 34
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10524 34
fruit fly
(Drosophila melanogaster)
Insecta SNF4Agamma 36 35
  • 63 (a)
worm
(Caenorhabditis elegans)
Secernentea aakg-1 34 35
  • 56.74 (n)
Y111B2A.8 36
  • 55 (a)
T20F7.6 36
  • 34 (a)
Y41G9A.3 36
  • 31 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SNF4 35
  • 34 (a)
OneToMany
rice
(Oryza sativa)
Liliopsida Os04g0401300 34
  • 42.46 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.7193 35
  • 49 (a)
OneToMany
Species where no ortholog for PRKAG1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for PRKAG1 Gene

ENSEMBL:
Gene Tree for PRKAG1 (if available)
TreeFam:
Gene Tree for PRKAG1 (if available)

Paralogs for PRKAG1 Gene

Paralogs for PRKAG1 Gene

genes like me logo Genes that share paralogs with PRKAG1: view

Variants for PRKAG1 Gene

Sequence variations from dbSNP and Humsavar for PRKAG1 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs139469030 Likely benign 49,019,138(+) GGAGA(A/G)AGGGC nc-transcript-variant, upstream-variant-2KB, utr-variant-3-prime
rs185652670 Likely benign 49,019,135(+) GAGGG(A/G)GAGAG nc-transcript-variant, upstream-variant-2KB, utr-variant-3-prime
rs190063096 Likely benign 49,019,736(+) CCTGT(G/T)GGAGT nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB, utr-variant-3-prime
rs192035980 Likely benign 49,020,965(+) TTGTT(A/G)TTGTT nc-transcript-variant, upstream-variant-2KB, utr-variant-3-prime
rs537330938 Likely benign 49,019,426(+) AAAAA(A/C)CAACC nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for PRKAG1 Gene

Variant ID Type Subtype PubMed ID
esv2662608 CNV deletion 23128226
nsv558833 CNV loss 21841781
nsv832404 CNV gain 17160897

Variation tolerance for PRKAG1 Gene

Residual Variation Intolerance Score: 25.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.69; 32.30% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PRKAG1 Gene

Human Gene Mutation Database (HGMD)
PRKAG1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
PRKAG1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PRKAG1 Gene

Disorders for PRKAG1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for PRKAG1 Gene - From: GeneCards

Disorder Aliases PubMed IDs
ascariasis
  • ascariasis - roundworm
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for PRKAG1

Genetic Association Database (GAD)
PRKAG1
Human Genome Epidemiology (HuGE) Navigator
PRKAG1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PRKAG1
genes like me logo Genes that share disorders with PRKAG1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PRKAG1 Gene

Publications for PRKAG1 Gene

  1. Non-catalytic beta- and gamma-subunit isoforms of the 5'-AMP- activated protein kinase. (PMID: 8621499) Gao G. … Witters L.A. (J. Biol. Chem. 1996) 2 3 4 64
  2. Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? (PMID: 20602615) RuaA+o G. … Wu A.H. (Pharmacogenomics 2010) 3 46 64
  3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey S.D. … Anand S. (Diabetes Care 2010) 3 46 64
  4. Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the diabetes prevention program. (PMID: 20682687) Jablonski K.A. … Florez J.C. (Diabetes 2010) 3 46 64
  5. Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study. (PMID: 20800603) Flachsbart F. … Nebel A. (Mutat. Res. 2010) 3 46 64

Products for PRKAG1 Gene

Sources for PRKAG1 Gene

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