Aliases for PRIM1 Gene
External Ids for PRIM1 Gene
Previous GeneCards Identifiers for PRIM1 Gene
The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the small, 49 kDa primase subunit. [provided by RefSeq, Jul 2008]
GeneCards Summary for PRIM1 Gene
PRIM1 (Primase (DNA) Subunit 1) is a Protein Coding gene. Among its related pathways are CDK-mediated phosphorylation and removal of Cdc6 and RB in Cancer. GO annotations related to this gene include DNA primase activity.
UniProtKB/Swiss-Prot for PRIM1 Gene
DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.