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PRICKLE3 Gene

protein-coding   GIFtS: 49
GCID: GC0XM049031

Prickle Homolog 3 (Drosophila)

(Previous name: LIM domain only 6)
(Previous symbol: LMO6)
  Search for PRICKLE3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Prickle Homolog 3 (Drosophila)1 2     LIM Domain Only Protein 62 3
LMO61 2 3 5     LIM Domain Only 61
Triple LIM Domain Protein 62 3     Prickle-Like Protein 32
LMO-62 3     

External Ids:    HGNC: 66451   Entrez Gene: 40072   Ensembl: ENSG000000122117   OMIM: 3001115   UniProtKB: O439003   

Export aliases for PRICKLE3 gene to outside databases

Previous GC identifers: GC0XM048919 GC0XM046689


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for PRICKLE3 Gene:
LIM domain only 6 is a three LIM domain-containing protein. The LIM domain is a cysteine-rich sequence motif that
binds zinc atoms to form a specific protein-binding interface for protein-protein interactions. (provided by
RefSeq, Jul 2008)

GeneCards Summary for PRICKLE3 Gene:
PRICKLE3 (prickle homolog 3 (Drosophila)) is a protein-coding gene. An important paralog of this gene is PRICKLE4.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the PRICKLE3 gene promoter:
         GR   c-Fos   AP-1   GR-beta   ATF-2   c-Ets-1   Egr-2   c-Jun   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPRICKLE3 promoter sequence
   Search Chromatin IP Primers for PRICKLE3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PRICKLE3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.23   Ensembl cytogenetic band:  Xp11.23   HGNC cytogenetic band: Xp11.23

PRICKLE3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PRICKLE3 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM049031:  view genomic region     (about GC identifiers)

Start:
49,031,151 bp from pter      End:
49,042,845 bp from pter
Size:
11,695 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: PRIC3_HUMAN, O43900 (See protein sequence)
Recommended Name: Prickle-like protein 3  
Size: 615 amino acids; 68609 Da
Secondary accessions: O76007 Q53XR5

Explore the universe of human proteins at neXtProt for PRICKLE3: NX_O43900

Explore proteomics data for PRICKLE3 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys126
  • Modification sites at PhosphoSitePlus

  • See PRICKLE3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_006141.2  
    ENSEMBL proteins: 
     ENSP00000365494   ENSP00000388599   ENSP00000390620   ENSP00000365487   ENSP00000401337  
     ENSP00000441743   ENSP00000441385   ENSP00000446051  

    PRICKLE3 Human Recombinant Protein Products:

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    OriGene Protein Over-expression Lysate for PRICKLE3
    OriGene Custom MassSpec
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    Novus Biologicals PRICKLE3 Protein
    Novus Biologicals PRICKLE3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PRICKLE3

     
    Search eBioscience for Proteins for PRICKLE3 

    PRICKLE3 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Abcam antibodies for PRICKLE3
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    ThermoFisher Antibodies for PRICKLE3
    LSBio Antibodies in human, mouse, rat for PRICKLE3

    PRICKLE3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for PRICKLE3
    Cloud-Clone Corp. CLIAs for PRICKLE3
    Search eBioscience for ELISAs for PRICKLE3 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR010442 PET_domain
     IPR001781 Znf_LIM

    Graphical View of Domain Structure for InterPro Entry O43900

    ProtoNet protein and cluster: O43900

    2 Blocks protein domains:
    IPB001781 Zn-binding protein
    IPB010442 PET


    UniProtKB/Swiss-Prot: PRIC3_HUMAN, O43900
    Similarity: Belongs to the prickle / espinas / testin family
    Similarity: Contains 3 LIM zinc-binding domains
    Similarity: Contains 1 PET domain


    Find genes that share domains with PRICKLE3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI17474147
    GO:0008270zinc ion binding IEA--
         
    Find genes that share ontologies with PRICKLE3           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for PRICKLE3:
     Decreased viability of wild-ty 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PRICKLE3
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PRICKLE3

    miRNA
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    miRTarBase miRNAs that target PRICKLE3:
    hsa-mir-26b-5p (MIRT028767), hsa-mir-106b-3p (MIRT038602)

    Block miRNA regulation of human, mouse, rat PRICKLE3 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate PRICKLE3
    SwitchGear 3'UTR luciferase reporter plasmidPRICKLE3 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for PRICKLE3
    Predesigned siRNA for gene silencing in human, mouse, rat PRICKLE3

    Gene Editing
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    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PRICKLE3 (NM_006150)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PRICKLE3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRICKLE3

    Cell Line
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--

    Find genes that share ontologies with PRICKLE3           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PRICKLE3
    Interactions:

        Search GeneGlobe Interaction Network for PRICKLE3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for PRICKLE3 (O439001, 2, 3 ENSP000003654944) via UniProtKB, MINT, STRING, and/or I2D (see all 32)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ABL1P005191, 2, 3, ENSP000003614234EBI-1751761,EBI-375543 MINT-8110491 I2D: score=3 STRING: ENSP00000361423
    FYNP062411, 2, 3, ENSP000003576564EBI-1751761,EBI-515315 MINT-8111331 I2D: score=3 STRING: ENSP00000357656
    SRCP129312, 3, ENSP000003509414MINT-8113143 I2D: score=3 STRING: ENSP00000350941
    CRKP461083, ENSP000003005744I2D: score=2 STRING: ENSP00000300574
    TRIM29Q141343, ENSP000003431294I2D: score=1 STRING: ENSP00000343129
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    Find genes that share ontologies with PRICKLE3           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PRICKLE3 (PRIC3)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for PRICKLE3 gene: 
    NM_006150.3  

    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000376317(uc004dmy.1 uc011mmx.1) ENST00000453382 ENST00000432913
    ENST00000376310 ENST00000417014 ENST00000538114 ENST00000536904(uc011mmw.1 uc011mmy.1)
    ENST00000540849(uc011mmv.1)
    miRNA
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    Block miRNA regulation of human, mouse, rat PRICKLE3 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate PRICKLE3
    SwitchGear 3'UTR luciferase reporter plasmidPRICKLE3 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for PRICKLE3
    Predesigned siRNA for gene silencing in human, mouse, rat PRICKLE3
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    OriGene ORF clones in mouse, rat for PRICKLE3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PRICKLE3 (NM_006150)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PRICKLE3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRICKLE3
    Primer
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    OriGene qPCR primer pairs and template standards for PRICKLE3
    OriGene qSTAR qPCR primer pairs in human, mouse for PRICKLE3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PRICKLE3
      QuantiTect SYBR Green Assays in human, mouse, rat PRICKLE3
      QuantiFast Probe-based Assays in human, mouse, rat PRICKLE3

    Selected AceView cDNA sequences (see all 181):

    AI688036 BQ893689 BX089443 BQ024547 AA322279 BQ057184 BU685092 BP353641 
    AI368248 BQ637168 BM699127 AA317404 BC032385 CB154970 AI124821 BC002468 
    AJ011654 BQ919604 BM925290 BU167864 BC064550 BU170706 BC016856 AW951240 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for PRICKLE3 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8 ^ 9 ^ 10a · 10b ^ 11
    SP1:                    -                 -     -           -                                             
    SP2:                                      -     -           -                                             
    SP3:                    -                 -                                                               
    SP4:                    -                 -     -                                                         
    SP5:                                                                                                      


    ECgene alternative splicing isoforms for PRICKLE3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PRICKLE3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCCTCACCC
    PRICKLE3 Expression
    About this image

    PRICKLE3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PRICKLE3 Protein Expression

    UniProtKB/Swiss-Prot: PRIC3_HUMAN, O43900
    Tissue specificity: Widely expressed

        Custom PCR Arrays for PRICKLE3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRICKLE3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for PRICKLE3 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Prickle31 , 5 prickle homolog 3 (Drosophila)1, 5 87.39(n)1
    92.91(a)1
      X (3.45 cM)5
    546301  NM_175097.31  NP_780306.11 
     76572605 
    lizard
    (Anolis carolinensis)
    Reptilia PRICKLE36
    prickle homolog 3 (Drosophila)
    63(a)
    1 ↔ 1
    1(205796466-205827759)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia prickle31 prickle homolog 3 (Drosophila) 60.14(n)
    57.61(a)
      100490600  XM_004916697.1  XP_004916754.1 
    zebrafish
    (Danio rerio)
    Actinopterygii prickle36
    prickle homolog 3 (Drosophila)
    46(a)
    1 ↔ 1
    8(51479372-51565446) ENSDARG00000073996
    fruit fly
    (Drosophila melanogaster)
    Insecta esn6
    pk6
    prickle
    22(a)
    19(a)
    many ↔ many
    many ↔ many
    2R(2973821-3015375)
    2R(3038207-3110885)
    worm
    (Caenorhabditis elegans)
    Secernentea prkl-16
    Protein PRKL-1, isoform a (prkl-1) mRNA, complete ...
    32(a)
    1 → many
    IV(6978775-6986935) WBGene00022727


    ENSEMBL Gene Tree for PRICKLE3 (if available)
    TreeFam Gene Tree for PRICKLE3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PRICKLE3 gene
    PRICKLE42  LMCD12  TES2  PRICKLE22  PRICKLE12  
    10 SIMAP similar genes for PRICKLE3 using alignment to 8 protein entries:     PRIC3_HUMAN (see all proteins):
    LMO6    PRICKLE2    PRICKLE1    RILP    DKFZp586B2022    FHL2
    TES    LIMS1    PRICKLE4    FHL3

    Find genes that share paralogs with PRICKLE3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PRICKLE3 (see all 213)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0361884
    A breast cancer sample4--see VAR_0361882 E D mis40--------
    rs1450369141,2
    C--48951367(+) GGGAAC/TGCTGA 1 -- ds50010--------
    rs1888573251,2
    --48951442(+) TTGAGC/GCTGCA 1 -- ds50010--------
    rs2008022261,2
    --48951619(+) TACTCC/TGACTG 1 -- ut310--------
    rs3679318071,2
    C--48951636(+) GGAGCC/GCCCTC 1 -- ut310--------
    rs1463175851,2
    F--48951687(+) CGGGCC/TTGACG 2 Q syn11Minor allele frequency- T:0.00NA 4362
    rs1996100341,2
    C--48951723(+) GGGAGC/G/TGATAA 3 S syn10--------
    rs1443904561,2
    F--48951842(+) TGATTC/TGGAAC 2 K E mis11Minor allele frequency- T:0.00NA 4550
    rs125579701,2
    C,F,H--48951843(+) GATTCG/AGAACT 2 /S syn1 ese312Minor allele frequency- A:0.07NS EA NA 5783
    rs1487914981,2
    F--48951856(+) AACTGG/CAGGGC 2 /S /C mis11Minor allele frequency- C:0.00NA 4550

    HapMap Linkage Disequilibrium report for PRICKLE3 (49031151 - 49042845 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for PRICKLE3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv528292CNV Gain19592680
    esv32909CNV Gain+Loss17666407
    nsv7442OTHER Inversion18451855
    nsv205OTHER Inversion15895083

    Locus Specific Mutation Databases (LSDB): PRICKLE3

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PRICKLE3
    DNA2.0 Custom Variant and Variant Library Synthesis for PRICKLE3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300111    OMIM disorders: --


    Find genes that share disorders with PRICKLE3           About GenesLikeMe


    Export disorders for PRICKLE3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PRICKLE3 gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with PRICKLE3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Sequence-based exon prediction around the synaptophysin locus reveals a gene-rich area containing novel genes in human proximal Xp. (PubMed id 9344658)1, 2, 3 Fisher S.E.... Craig I.W. (Genomics 1997)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    4. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    5. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R.... Peters J.M. (Science 2010)
    6. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (Cell 2010)
    7. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    8. Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)1 Wu C....Li S.S. (Proteomics 2007)
    9. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1 Olsen J.V....Mann M. (Cell 2006)
    10. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

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    Entrez Gene: 4007 HGNC: 6645 AceView: SYPandLMO6 Ensembl:ENSG00000012211 euGenes: HUgn4007
    ECgene: PRICKLE3 H-InvDB: PRICKLE3

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for PRICKLE3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for PRICKLE3 gene:
    Search GeneIP for patents involving PRICKLE3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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