Aliases for PRICKLE2 Gene
External Ids for PRICKLE2 Gene
Previous GeneCards Identifiers for PRICKLE2 Gene
This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5. [provided by RefSeq, Dec 2011]
GeneCards Summary for PRICKLE2 Gene
PRICKLE2 (Prickle Planar Cell Polarity Protein 2) is a Protein Coding gene. Diseases associated with PRICKLE2 include epilepsy, progressive myoclonic 5 and cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 3. Among its related pathways are Wnt signaling pathway (KEGG). An important paralog of this gene is LMCD1.