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Aliases for PRG1 Gene

Subcategory (RNA class) for PRG1 Gene

lncRNA

Quality Score for this RNA gene is

1

Aliases for PRG1 Gene

  • P53-Responsive Gene 1 3

External Ids for PRG1 Gene

ORGUL Members for PRG1 Gene

Previous GeneCards Identifiers for PRG1 Gene

  • GC10P069659
  • GC10P069934
  • GC10P070740
  • GC10P070192
  • GC10P070171
  • GC10P070517
  • GC19U900736
  • GC19P043853

Summaries for PRG1 Gene

GeneCards Summary for PRG1 Gene

PRG1 (P53-Responsive Gene 1) is an RNA Gene, and is affiliated with the lncRNA class.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRG1 Gene

Genomics for PRG1 Gene

Regulatory Elements for PRG1 Gene

Enhancers for PRG1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G043352 0.6 FANTOM5 0.7 +3.3 3270 0.4 ZSCAN21 GLIS1 ZNF169 ZNF558 ZNF112 EZH2 CD177 PRG1
GH19G043341 0.8 Ensembl 0.4 -6.9 -6911 0.9 FEZF1 ZNF366 PATZ1 ZNF600 PRDM10 KLF8 ZBTB10 MAZ ZNF114 YY2 IRGQ LOC100505715 ENSG00000267191 ENSG00000231412 ZNF404 ZNF223 PINLYP ZNF225 CD177 PRG1
GH19G043332 0.7 ENCODE 0.4 -16.1 -16137 1.5 CTCF ZSCAN26 ZSCAN4 BCL11B RAD21 ZNF155 ZNF138 SMC3 ZBTB10 ELF1 ZNF225 ZNF45 ZNF284 ZNF224 ZNF234 ZNF223 ZNF230 ENSG00000231412 PINLYP XRCC1
GH19G043331 0.7 ENCODE 0.4 -17.4 -17438 0.3 ZNF263 ZNF777 ZSCAN26 ZNF114 ZSCAN4 SALL2 ZNF311 ZNF544 GLIS1 ZNF350 ZNF225 IRGQ LOC100505715 ZNF223 ENSG00000231412 ZNF45 ZNF284 ZNF404 PINLYP ZNF230
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around PRG1 on UCSC Golden Path with GeneCards custom track

Genomic Location for PRG1 Gene

Chromosome:
19
Start:
43,349,056 bp from pter
End:
43,349,548 bp from pter
Size:
493 bases
Orientation:
Plus strand

Genomic View for PRG1 Gene

Genes around PRG1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRG1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRG1 Gene

Proteins for PRG1 Gene

  • Protein details for PRG1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A024QZL1
    Recommended name:
    Proteoglycan 1, secretory granule, isoform CRA_a
    Protein Accession:
    A0A024QZL1

    Protein attributes for PRG1 Gene

    Size:
    158 amino acids
    Molecular mass:
    17624 Da
    Quaternary structure:
    No Data Available
  • Protein details for PRG1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Q0EFC0
    Recommended name:
    PRG1 protein
    Protein Accession:
    Q0EFC0

    Protein attributes for PRG1 Gene

    Size:
    156 amino acids
    Molecular mass:
    16590 Da
    Quaternary structure:
    No Data Available
  • Protein details for PRG1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Q5ST77
    Recommended name:
    Immediate early response 3
    Protein Accession:
    Q5ST77

    Protein attributes for PRG1 Gene

    Size:
    156 amino acids
    Molecular mass:
    16929 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PRG1 Gene

Post-translational modifications for PRG1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PRG1 Gene

Domains & Families for PRG1 Gene

Protein Domains for PRG1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for PRG1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PRG1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for PRG1 Gene

Function for PRG1 Gene

Molecular function for PRG1 Gene

GENATLAS Biochemistry:
platelet proteoglycan,core of secretory granule,17.6kDa

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRG1 Gene

Localization for PRG1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PRG1 Gene

Pathways & Interactions for PRG1 Gene

No Data Available

Interacting Proteins for PRG1 Gene

Gene Ontology (GO) - Biological Process for PRG1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PRG1 Gene

Drugs & Compounds for PRG1 Gene

No Compound Related Data Available

Transcripts for PRG1 Gene

mRNA/cDNA for PRG1 Gene

(1) Additional mRNA sequences :

Unigene Clusters for PRG1 Gene

P53-responsive gene 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PRG1 Gene

No ASD Table

Relevant External Links for PRG1 Gene

GeneLoc Exon Structure for
PRG1

Expression for PRG1 Gene

SOURCE GeneReport for Unigene cluster for PRG1 Gene:

Hs.721578
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PRG1 Gene

Orthologs for PRG1 Gene

No data available for Orthologs and Evolution for PRG1 Gene

Paralogs for PRG1 Gene

(2) SIMAP similar genes for PRG1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with PRG1: view

No data available for Paralogs for PRG1 Gene

Variants for PRG1 Gene

Sequence variations from dbSNP and Humsavar for PRG1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000785530 -- 43,348,283(+) GGAAG(A/G)CTAGA upstream-variant-2KB
rs1001577404 -- 43,348,643(+) TTTTG(A/C)GATGG upstream-variant-2KB
rs1006811411 -- 43,347,920(+) GGGGG(C/T)CTTGC upstream-variant-2KB
rs1007170023 -- 43,348,113(+) GGCCT(G/T)GAACT upstream-variant-2KB
rs1008423448 -- 43,349,302(+) CTGTA(A/T)TGGGC nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for PRG1 Gene

Variant ID Type Subtype PubMed ID
dgv3591n100 CNV loss 25217958
dgv3603n100 CNV gain 25217958
dgv6497n54 CNV loss 21841781
dgv6502n54 CNV loss 21841781
esv2751795 CNV loss 17911159
esv2758763 CNV gain+loss 17122850
esv3644464 CNV loss 21293372
nsv1056633 CNV loss 25217958
nsv1057657 CNV gain 25217958
nsv1057682 CNV loss 25217958
nsv2500 CNV insertion 18451855
nsv469666 CNV loss 16826518
nsv469787 CNV loss 16826518
nsv516973 CNV gain+loss 19592680
nsv526966 CNV loss 19592680

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for PRG1 Gene

Disorders for PRG1 Gene

Relevant External Links for PRG1

Genetic Association Database (GAD)
PRG1
Human Genome Epidemiology (HuGE) Navigator
PRG1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PRG1

No disorders were found for PRG1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRG1 Gene

Publications for PRG1 Gene

  1. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3 46 64
  2. Molecular cause and functional impact of altered synaptic lipid signaling due to a prg-1 gene SNP. (PMID: 26671989) Vogt J. … Nitsch R. (EMBO Mol Med 2016) 3 64
  3. P53 and K-ras mutations are frequent events in microscopically negative surgical margins from patients with nonsmall cell lung carcinoma. (PMID: 15112277) Jassem J. … Zylicz M. (Cancer 2004) 3 64
  4. p53 overexpression as a prognostic indicator in endometrial carcinoma. (PMID: 12807239) Ozalp S. … Erol G. (Eur. J. Gynaecol. Oncol. 2003) 3 64
  5. p53 gene mutations are associated with poor survival in low and low-intermediate risk diffuse large B-cell lymphomas. (PMID: 12176791) Leroy K. … Gaulard P. (Ann. Oncol. 2002) 3 64

Products for PRG1 Gene

Sources for PRG1 Gene

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