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Aliases for PRG1 Gene

Subcategory (RNA class) for PRG1 Gene

lncRNA

Quality Score for this RNA gene is

1

Aliases for PRG1 Gene

  • P53-Responsive Gene 1 3

External Ids for PRG1 Gene

ORGUL Members for PRG1 Gene

Previous GeneCards Identifiers for PRG1 Gene

  • GC10P069659
  • GC10P069934
  • GC10P070740
  • GC10P070192
  • GC10P070171
  • GC10P070517
  • GC19U900736
  • GC19P043853

Summaries for PRG1 Gene

GeneCards Summary for PRG1 Gene

PRG1 (P53-Responsive Gene 1) is an RNA Gene, and is affiliated with the lncRNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRG1 Gene

Genomics for PRG1 Gene

Regulatory Elements for PRG1 Gene

Enhancers for PRG1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F043352 0.5 FANTOM5 0.8 +3.3 3270 0.4 ZNF169 GLIS1 ZNF558 CD177 PRG1
GH19F043341 0.7 Ensembl 0.4 -6.9 -6911 0.9 ZBTB10 MAZ YY2 FEZF1 OSR2 ZFP69B ZNF366 ZNF692 PATZ1 PRDM10 ENSG00000231412 CD177 ENSG00000267191 PRG1
GH19F043332 0.7 ENCODE 0.3 -16.1 -16137 1.5 ZBTB10 CTCF BCL11B ZNF843 RAD21 NR2F2 ZNF155 ZNF138 ZNF747 GLIS1 ZNF45 ZNF225 ZNF224 ZNF234 ZNF284 ZNF230 ENSG00000231412 XRCC1 PRG1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around PRG1 on UCSC Golden Path with GeneCards custom track

Genomic Location for PRG1 Gene

Chromosome:
19
Start:
43,349,056 bp from pter
End:
43,349,548 bp from pter
Size:
493 bases
Orientation:
Plus strand

Genomic View for PRG1 Gene

Genes around PRG1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRG1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRG1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRG1 Gene

Proteins for PRG1 Gene

  • Protein details for PRG1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A024QZL1
    Recommended name:
    Proteoglycan 1, secretory granule, isoform CRA_a
    Protein Accession:
    A0A024QZL1

    Protein attributes for PRG1 Gene

    Size:
    158 amino acids
    Molecular mass:
    17624 Da
    Quaternary structure:
    No Data Available
  • Protein details for PRG1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Q0EFC0
    Recommended name:
    PRG1 protein
    Protein Accession:
    Q0EFC0

    Protein attributes for PRG1 Gene

    Size:
    156 amino acids
    Molecular mass:
    16590 Da
    Quaternary structure:
    No Data Available
  • Protein details for PRG1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Q5ST77
    Recommended name:
    Immediate early response 3
    Protein Accession:
    Q5ST77

    Protein attributes for PRG1 Gene

    Size:
    156 amino acids
    Molecular mass:
    16929 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PRG1 Gene

Post-translational modifications for PRG1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PRG1 Gene

Domains & Families for PRG1 Gene

Protein Domains for PRG1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for PRG1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PRG1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for PRG1 Gene

Function for PRG1 Gene

Molecular function for PRG1 Gene

GENATLAS Biochemistry:
platelet proteoglycan,core of secretory granule,17.6kDa

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRG1 Gene

Localization for PRG1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PRG1 Gene

Pathways & Interactions for PRG1 Gene

No Data Available

Interacting Proteins for PRG1 Gene

Gene Ontology (GO) - Biological Process for PRG1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PRG1 Gene

Transcripts for PRG1 Gene

mRNA/cDNA for PRG1 Gene

(1) Additional mRNA sequences :

Unigene Clusters for PRG1 Gene

P53-responsive gene 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PRG1 Gene

No ASD Table

Relevant External Links for PRG1 Gene

GeneLoc Exon Structure for
PRG1

Expression for PRG1 Gene

SOURCE GeneReport for Unigene cluster for PRG1 Gene:

Hs.721578
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for PRG1 Gene

Orthologs for PRG1 Gene

No data available for Orthologs and Evolution for PRG1 Gene

Paralogs for PRG1 Gene

(2) SIMAP similar genes for PRG1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with PRG1: view

No data available for Paralogs for PRG1 Gene

Variants for PRG1 Gene

Sequence variations from dbSNP and Humsavar for PRG1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs111735390 -- 43,348,787(+) GCTAA(G/T)TTTTG upstream-variant-2KB
rs112059502 -- 43,348,781(+) TGCCC(A/G)GCTAA upstream-variant-2KB
rs112406166 -- 43,347,358(+) AAAGT(A/G)AGCTA upstream-variant-2KB
rs113901011 -- 43,347,594(+) AAGCA(A/G)TCTGG upstream-variant-2KB
rs115165535 -- 43,347,243(+) AAAAA(A/T)AAATC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for PRG1 Gene

Variant ID Type Subtype PubMed ID
dgv3591n100 CNV loss 25217958
dgv3603n100 CNV gain 25217958
dgv6497n54 CNV loss 21841781
dgv6502n54 CNV loss 21841781
esv2751795 CNV loss 17911159
esv2758763 CNV gain+loss 17122850
esv3644464 CNV loss 21293372
nsv1056633 CNV loss 25217958
nsv1057657 CNV gain 25217958
nsv1057682 CNV loss 25217958
nsv2500 CNV insertion 18451855
nsv469666 CNV loss 16826518
nsv469787 CNV loss 16826518
nsv516973 CNV gain+loss 19592680
nsv526966 CNV loss 19592680

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Variation tolerance and Relevant External Links for PRG1 Gene

Disorders for PRG1 Gene

Relevant External Links for PRG1

Genetic Association Database (GAD)
PRG1
Human Genome Epidemiology (HuGE) Navigator
PRG1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PRG1

No disorders were found for PRG1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRG1 Gene

Publications for PRG1 Gene

  1. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 3 46 64
  2. Molecular cause and functional impact of altered synaptic lipid signaling due to a prg-1 gene SNP. (PMID: 26671989) Vogt J. … Nitsch R. (EMBO Mol Med 2016) 3 64
  3. P53 and K-ras mutations are frequent events in microscopically negative surgical margins from patients with nonsmall cell lung carcinoma. (PMID: 15112277) Jassem J. … Zylicz M. (Cancer 2004) 3 64
  4. p53 overexpression as a prognostic indicator in endometrial carcinoma. (PMID: 12807239) Ozalp S. … Erol G. (Eur. J. Gynaecol. Oncol. 2003) 3 64
  5. p53 gene mutations are associated with poor survival in low and low-intermediate risk diffuse large B-cell lymphomas. (PMID: 12176791) Leroy K. … Gaulard P. (Ann. Oncol. 2002) 3 64

Products for PRG1 Gene

Sources for PRG1 Gene

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