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Aliases for PRG1 Gene

Subcategory (RNA class) for PRG1 Gene

lncRNA

Quality Score for this RNA gene is

1

Aliases for PRG1 Gene

  • P53-Responsive Gene 1 3

External Ids for PRG1 Gene

ORGUL Members for PRG1 Gene

Previous GeneCards Identifiers for PRG1 Gene

  • GC10P069659
  • GC10P069934
  • GC10P070740
  • GC10P070192
  • GC10P070171
  • GC10P070517
  • GC19U900736
  • GC19P043853

Summaries for PRG1 Gene

GeneCards Summary for PRG1 Gene

PRG1 (P53-Responsive Gene 1) is an RNA Gene, and is affiliated with the lncRNA class.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRG1 Gene

Genomics for PRG1 Gene

Regulatory Elements for PRG1 Gene

Genomic Location for PRG1 Gene

Chromosome:
19
Start:
43,349,056 bp from pter
End:
43,349,548 bp from pter
Size:
493 bases
Orientation:
Plus strand

Genomic View for PRG1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for PRG1 Gene

Proteins for PRG1 Gene

  • Protein details for PRG1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A024QZL1
    Recommended name:
    Proteoglycan 1, secretory granule, isoform CRA_a
    Protein Accession:
    A0A024QZL1

    Protein attributes for PRG1 Gene

    Size:
    158 amino acids
    Molecular mass:
    17624 Da
    Quaternary structure:
    No Data Available
  • Protein details for PRG1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Q0EFC0
    Recommended name:
    PRG1 protein
    Protein Accession:
    Q0EFC0

    Protein attributes for PRG1 Gene

    Size:
    156 amino acids
    Molecular mass:
    16590 Da
    Quaternary structure:
    No Data Available
  • Protein details for PRG1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Q5ST77
    Recommended name:
    Immediate early response 3
    Protein Accession:
    Q5ST77

    Protein attributes for PRG1 Gene

    Size:
    156 amino acids
    Molecular mass:
    16929 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PRG1 Gene

Proteomics data for PRG1 Gene at MOPED

Post-translational modifications for PRG1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for PRG1 Gene

Domains & Families for PRG1 Gene

Protein Domains for PRG1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for PRG1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PRG1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for PRG1 Gene

Function for PRG1 Gene

Molecular function for PRG1 Gene

GENATLAS Biochemistry:
platelet proteoglycan,core of secretory granule,17.6kDa

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRG1 Gene

Localization for PRG1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PRG1 Gene

Pathways & Interactions for PRG1 Gene

SuperPathways for PRG1 Gene

No Data Available

Interacting Proteins for PRG1 Gene

Gene Ontology (GO) - Biological Process for PRG1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PRG1 Gene

Drugs & Compounds for PRG1 Gene

No Compound Related Data Available

Transcripts for PRG1 Gene

mRNA/cDNA for PRG1 Gene

(1) Additional mRNA sequences :

Unigene Clusters for PRG1 Gene

P53-responsive gene 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PRG1 Gene

No ASD Table

Relevant External Links for PRG1 Gene

GeneLoc Exon Structure for
PRG1

Expression for PRG1 Gene

SOURCE GeneReport for Unigene cluster for PRG1 Gene Hs.721578

No Expression Related Data Available

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for PRG1 Gene

Orthologs for PRG1 Gene

No data available for Orthologs and Evolution for PRG1 Gene

Paralogs for PRG1 Gene

(2) SIMAP similar genes for PRG1 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with PRG1: view

No data available for Paralogs for PRG1 Gene

Variants for PRG1 Gene

Sequence variations from dbSNP and Humsavar for PRG1 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs3745999 -- 43,349,353(-) CACAT(A/G)ATGCT nc-transcript-variant
rs4803612 -- 43,347,120(+) GGTAT(A/G)GTGGC upstream-variant-2KB
rs8099964 -- 43,347,913(+) TTTGA(C/G)AGGGG upstream-variant-2KB
rs8113760 -- 43,347,783(+) GCCTT(A/G)TGGCC upstream-variant-2KB
rs11670832 -- 43,348,663(+) ctgtc(A/G)cccag upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for PRG1 Gene

Variant ID Type Subtype PubMed ID
dgv1087e1 CNV Complex 17122850
nsv516973 CNV Gain+Loss 19592680
esv2751795 CNV Loss 17911159
essv22369 CNV CNV 17122850
nsv469787 CNV Loss 16826518
essv21588 CNV CNV 17122850
nsv469666 CNV Complex 16826518
nsv526966 CNV Loss 19592680
nsv2500 CNV Insertion 18451855

Relevant External Links for PRG1 Gene

HapMap Linkage Disequilibrium report
PRG1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for PRG1 Gene

Disorders for PRG1 Gene

Relevant External Links for PRG1

Genetic Association Database (GAD)
PRG1
Human Genome Epidemiology (HuGE) Navigator
PRG1
genes like me logo Genes that share disorders with PRG1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRG1 Gene

Publications for PRG1 Gene

  1. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PMID: 16385451) Grupe A. … Goate A. (Am. J. Hum. Genet. 2006) 67
  2. P53 and K-ras mutations are frequent events in microscopically negative surgical margins from patients with nonsmall cell lung carcinoma. (PMID: 15112277) Jassem J. … Zylicz M. (Cancer 2004) 67
  3. p53 overexpression as a prognostic indicator in endometrial carcinoma. (PMID: 12807239) Ozalp S. … Erol G. (Eur. J. Gynaecol. Oncol. 2003) 67
  4. p53 gene mutations are associated with poor survival in low and low-intermediate risk diffuse large B-cell lymphomas. (PMID: 12176791) Leroy K. … Gaulard P. (Ann. Oncol. 2002) 67
  5. Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PMID: 10737800) Dias Neto E. … Simpson A.J.G. (Proc. Natl. Acad. Sci. U.S.A. 2000) 67

Products for PRG1 Gene

Sources for PRG1 Gene

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