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Aliases for PRELID2 Gene

Aliases for PRELID2 Gene

  • PRELI Domain Containing 2 2 3 5
  • CTC-806A22.1 3

External Ids for PRELID2 Gene

Previous GeneCards Identifiers for PRELID2 Gene

  • GC05M145119
  • GC05M144851
  • GC05M140285
  • GC05M145471

Summaries for PRELID2 Gene

GeneCards Summary for PRELID2 Gene

PRELID2 (PRELI Domain Containing 2) is a Protein Coding gene. GO annotations related to this gene include phosphatidic acid transporter activity. An important paralog of this gene is PRELID3B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRELID2 Gene

Genomics for PRELID2 Gene

Regulatory Elements for PRELID2 Gene

Promoters for PRELID2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around PRELID2 on UCSC Golden Path with GeneCards custom track

Genomic Location for PRELID2 Gene

Chromosome:
5
Start:
145,337,932 bp from pter
End:
145,835,383 bp from pter
Size:
497,452 bases
Orientation:
Minus strand

Genomic View for PRELID2 Gene

Genes around PRELID2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRELID2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRELID2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRELID2 Gene

Proteins for PRELID2 Gene

  • Protein details for PRELID2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N945-PRLD2_HUMAN
    Recommended name:
    PRELI domain-containing protein 2
    Protein Accession:
    Q8N945
    Secondary Accessions:
    • G5EA01
    • Q96EQ3

    Protein attributes for PRELID2 Gene

    Size:
    189 amino acids
    Molecular mass:
    21905 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BQ425760; Type=Frameshift; Positions=143, 169; Evidence={ECO:0000305};

    Alternative splice isoforms for PRELID2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for PRELID2 Gene

Proteomics data for PRELID2 Gene at MOPED

Post-translational modifications for PRELID2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PRELID2 Gene

No data available for DME Specific Peptides for PRELID2 Gene

Domains & Families for PRELID2 Gene

Protein Domains for PRELID2 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for PRELID2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N945

UniProtKB/Swiss-Prot:

PRLD2_HUMAN :
  • Contains 1 PRELI/MSF1 domain.
Domain:
  • Contains 1 PRELI/MSF1 domain.
genes like me logo Genes that share domains with PRELID2: view

No data available for Gene Families for PRELID2 Gene

Function for PRELID2 Gene

Phenotypes for PRELID2 Gene

GenomeRNAi human phenotypes for PRELID2:
genes like me logo Genes that share phenotypes with PRELID2: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for PRELID2 Gene

Localization for PRELID2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for PRELID2 Gene COMPARTMENTS Subcellular localization image for PRELID2 gene
Compartment Confidence
mitochondrion 4
nucleus 3
cytosol 2
endoplasmic reticulum 1
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for PRELID2 Gene

Pathways & Interactions for PRELID2 Gene

SuperPathways for PRELID2 Gene

No Data Available

Interacting Proteins for PRELID2 Gene

Gene Ontology (GO) - Biological Process for PRELID2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for PRELID2 Gene

Drugs & Compounds for PRELID2 Gene

No Compound Related Data Available

Transcripts for PRELID2 Gene

Unigene Clusters for PRELID2 Gene

PRELI domain containing 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for PRELID2 Gene

ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c
SP1: - - -
SP2: - - -
SP3: - - - - -
SP4: - - -
SP5: -

Relevant External Links for PRELID2 Gene

GeneLoc Exon Structure for
PRELID2
ECgene alternative splicing isoforms for
PRELID2

Expression for PRELID2 Gene

mRNA expression in normal human tissues for PRELID2 Gene

mRNA differential expression in normal tissues according to GTEx for PRELID2 Gene

This gene is overexpressed in Colon - Transverse (x6.4).

Protein differential expression in normal tissues from HIPED for PRELID2 Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PRELID2 Gene



SOURCE GeneReport for Unigene cluster for PRELID2 Gene Hs.314261

genes like me logo Genes that share expression patterns with PRELID2: view

Protein tissue co-expression partners for PRELID2 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for PRELID2 Gene

Orthologs for PRELID2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for PRELID2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PRELID2 36
  • 100 (a)
OneToOne
PRELID2 35
  • 99.25 (n)
  • 100 (a)
cow
(Bos Taurus)
Mammalia LOC524741 35
  • 90.09 (n)
  • 89.19 (a)
PRELID2 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia PRELID2 36
  • 95 (a)
OneToOne
PRELID2 35
  • 92.66 (n)
  • 94.92 (a)
mouse
(Mus musculus)
Mammalia Prelid2 36
  • 89 (a)
OneToOne
Prelid2 16
Prelid2 35
  • 88.14 (n)
  • 88.7 (a)
oppossum
(Monodelphis domestica)
Mammalia PRELID2 36
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia PRELID2 36
  • 84 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Prelid2 35
  • 88.51 (n)
  • 88.14 (a)
lizard
(Anolis carolinensis)
Reptilia PRELID2 36
  • 68 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.8114 35
tropical clawed frog
(Silurana tropicalis)
Amphibia prelid2 35
  • 64.77 (n)
  • 60.8 (a)
Str.15586 35
Species with no ortholog for PRELID2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PRELID2 Gene

ENSEMBL:
Gene Tree for PRELID2 (if available)
TreeFam:
Gene Tree for PRELID2 (if available)

Paralogs for PRELID2 Gene

Paralogs for PRELID2 Gene

(1) SIMAP similar genes for PRELID2 Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for PRELID2 Gene

genes like me logo Genes that share paralogs with PRELID2: view

Variants for PRELID2 Gene

Sequence variations from dbSNP and Humsavar for PRELID2 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs9324996 - 145,818,002(+) GAGGA(C/T)TGAGC nc-transcript-variant, reference, missense
rs26157 -- 145,360,437(-) CTGGA(C/T)CTTCG intron-variant
rs26158 -- 145,359,951(-) CTCAC(A/G)GTCAA intron-variant
rs26159 -- 145,358,531(-) AGACT(A/G)TATCC intron-variant
rs26160 -- 145,353,893(-) AATCT(A/G)GAAAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PRELID2 Gene

Variant ID Type Subtype PubMed ID
nsv462474 CNV Loss 19166990
esv23730 CNV Gain 19812545

Variation tolerance for PRELID2 Gene

Residual Variation Intolerance Score: 49.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.29; 53.14% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PRELID2 Gene

HapMap Linkage Disequilibrium report
PRELID2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PRELID2 Gene

Disorders for PRELID2 Gene

Relevant External Links for PRELID2

Genetic Association Database (GAD)
PRELID2
Human Genome Epidemiology (HuGE) Navigator
PRELID2
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PRELID2

No disorders were found for PRELID2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRELID2 Gene

Publications for PRELID2 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson S.L. … O'Brien S.J. (PLoS ONE 2010) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for PRELID2 Gene

Sources for PRELID2 Gene

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