Aliases for PRDX6 Gene
External Ids for PRDX6 Gene
Previous GeneCards Identifiers for PRDX6 Gene
The protein encoded by this gene is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury. [provided by RefSeq, Jul 2008]
GeneCards Summary for PRDX6 Gene
PRDX6 (Peroxiredoxin 6) is a Protein Coding gene. Diseases associated with PRDX6 include Gnathomiasis and Fuchs' Endothelial Dystrophy. Among its related pathways are Cellular Senescence and Detoxification of Reactive Oxygen Species. GO annotations related to this gene include oxidoreductase activity and antioxidant activity.
UniProtKB/Swiss-Prot for PRDX6 Gene
Involved in redox regulation of the cell. Can reduce H(2)O(2) and short chain organic, fatty acid, and phospholipid hydroperoxides. May play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.