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Aliases for PRDX1 Gene

Aliases for PRDX1 Gene

  • Peroxiredoxin 1 2 3 5
  • Thioredoxin-Dependent Peroxide Reductase 2 3 4
  • Natural Killer Cell-Enhancing Factor A 3 4
  • Proliferation-Associated Gene Protein 3 4
  • Thioredoxin Peroxidase 2 3 4
  • EC 1.11.1.15 4 58
  • NKEF-A 3 4
  • TDPX2 3 4
  • PAGA 3 4
  • PAGB 3 4
  • PAG 3 4
  • Natural Killer-Enhancing Factor A 3
  • Proliferation-Associated Gene A 3
  • Peroxiredoxin-1 3
  • EC 1.11.1 58
  • MSP23 3
  • NKEFA 3
  • PRX1 3
  • PRXI 3

External Ids for PRDX1 Gene

Previous HGNC Symbols for PRDX1 Gene

  • PAGA

Previous GeneCards Identifiers for PRDX1 Gene

  • GC01M045704
  • GC01M044978
  • GC01M045404
  • GC01M045390
  • GC01M045645
  • GC01M045749
  • GC01M045976
  • GC01M044090

Summaries for PRDX1 Gene

Entrez Gene Summary for PRDX1 Gene

  • This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Four transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jan 2011]

GeneCards Summary for PRDX1 Gene

PRDX1 (Peroxiredoxin 1) is a Protein Coding gene. Diseases associated with PRDX1 include Anthrax Disease and Cutaneous Anthrax. Among its related pathways are HIV Life Cycle and Cellular Senescence (REACTOME). GO annotations related to this gene include poly(A) RNA binding and identical protein binding. An important paralog of this gene is PRDX2.

UniProtKB/Swiss-Prot for PRDX1 Gene

  • Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (PubMed:9497357). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).

Gene Wiki entry for PRDX1 Gene

Additional gene information for PRDX1 Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRDX1 Gene

Genomics for PRDX1 Gene

Regulatory Elements for PRDX1 Gene

Enhancers for PRDX1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H045498 1.1 ENCODE 36.8 +23.1 23067 3 HDGF PKNOX1 FOXA2 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 CCDC163 PRDX1 MUTYH LRRC41 TOE1 TMA16P2 LOC110117498 NASP GPBP1L1 AKR1A1
GH01H045541 1.7 FANTOM5 Ensembl ENCODE 22.9 -20.8 -20804 4 HDGF FOXA2 PKNOX1 MLX ZFP64 ARID4B DMAP1 YY1 ATF7 RUNX3 CCDC163 PRDX1 IPP AKR1A1 MMACHC TESK2 GPBP1L1 TOE1 GC01P045551 HMGB1P48
GH01H045409 1.4 FANTOM5 Ensembl ENCODE 25.8 +111.8 111756 3 HDAC1 ZBTB40 ZNF766 GATA2 ELK1 FOS ATF7 RUNX3 CREM USF2 PRDX1 TESK2 HMGB1P48 MMACHC CCDC163 IPP PPIAP36 PIR46302
GH01H045520 1.2 ENCODE 26 +1.2 1187 3 MLX ZFP64 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 SP3 NFYC ZC3H11A CCDC163 TOE1 LRRC41 MUTYH GPBP1L1 NASP PRDX1 ZSWIM5 RPS8 PTCH2
GH01H045489 1.1 ENCODE 25.6 +32.1 32138 2 HDGF PKNOX1 FOXA2 ARNT ZFP64 ARID4B SIN3A FEZF1 DMAP1 ZNF2 CCDC163 NSUN4 PRDX1 LRRC41 TOE1 IPP GPBP1L1 KIF2C ZSWIM5 MMACHC
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around PRDX1 on UCSC Golden Path with GeneCards custom track

Promoters for PRDX1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000005862 1847 2401 MLX ZFP64 FEZF1 DMAP1 YY1 SLC30A9 ZNF416 ZNF143 SP3 NFYC

Genomic Location for PRDX1 Gene

Chromosome:
1
Start:
45,511,035 bp from pter
End:
45,523,047 bp from pter
Size:
12,013 bases
Orientation:
Minus strand

Genomic View for PRDX1 Gene

Genes around PRDX1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRDX1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRDX1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRDX1 Gene

Proteins for PRDX1 Gene

  • Protein details for PRDX1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q06830-PRDX1_HUMAN
    Recommended name:
    Peroxiredoxin-1
    Protein Accession:
    Q06830
    Secondary Accessions:
    • B5BU26
    • D3DPZ8
    • P35703
    • Q2V576
    • Q5T154
    • Q5T155

    Protein attributes for PRDX1 Gene

    Size:
    199 amino acids
    Molecular mass:
    22110 Da
    Quaternary structure:
    • Homodimer; disulfide-linked, upon oxidation. 5 homodimers assemble to form a ring-like decamer (PubMed:18172504). Interacts with GDPD5; forms a mixed-disulfide with GDPD5 (By similarity). Interacts with SESN1 and SESN2 (PubMed:15105503).
    Miscellaneous:
    • The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this typical 2-Cys peroxiredoxin, C(R) is provided by the other dimeric subunit to form an intersubunit disulfide. The disulfide is subsequently reduced by thioredoxin.
    SequenceCaution:
    • Sequence=CAI13097.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for PRDX1 Gene

neXtProt entry for PRDX1 Gene

Selected DME Specific Peptides for PRDX1 Gene

Q06830:
  • FKATAVMPDGQFKDISL
  • HGEVCPA
  • LRLVQAFQ
  • VGRSVDE
  • LSDYKGK
  • IDDKGILR
  • EVCPAGWKPG
  • NDLPVGR
  • GRSVDET
  • LRQITVND
  • SKEYFSK
  • RGLFIID
  • DFTFVCP
  • PGSDTIKP
  • ASVDSHFCHLAW

Post-translational modifications for PRDX1 Gene

  • Phosphorylated on Thr-90 during the M-phase, which leads to a more than 80% decrease in enzymatic activity.
  • The enzyme can be inactivated by further oxidation of the cysteine sulfenic acid (C(P)-SOH) to sulphinic acid (C(P)-SO2H) instead of its condensation to a disulfide bond. It can be reactivated by forming a transient disulfide bond with sulfiredoxin SRXN1, which reduces the cysteine sulfinic acid in an ATP- and Mg-dependent manner.
  • Ubiquitination at isoforms=93
  • Modification sites at PhosphoSitePlus

Other Protein References for PRDX1 Gene

Antibody Products

  • R&D Systems Antibodies for PRDX1 (Peroxiredoxin 1)
  • Cell Signaling Technology (CST) Antibodies for PRDX1 (PRDX1)

Domains & Families for PRDX1 Gene

Gene Families for PRDX1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins

Suggested Antigen Peptide Sequences for PRDX1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q06830

UniProtKB/Swiss-Prot:

PRDX1_HUMAN :
  • Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
Family:
  • Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
genes like me logo Genes that share domains with PRDX1: view

Function for PRDX1 Gene

Molecular function for PRDX1 Gene

UniProtKB/Swiss-Prot CatalyticActivity:
2 R-SH + ROOH = R-S-S-R + H(2)O + ROH.
UniProtKB/Swiss-Prot Function:
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2) (PubMed:9497357). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation (By similarity).
UniProtKB/Swiss-Prot Induction:
Constitutively expressed in most human cells; is induced to higher levels upon serum stimulation in untransformed and transformed cells.

Enzyme Numbers (IUBMB) for PRDX1 Gene

Phenotypes From GWAS Catalog for PRDX1 Gene

Gene Ontology (GO) - Molecular Function for PRDX1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding IDA 22658674
GO:0004601 peroxidase activity TAS --
GO:0005515 protein binding IPI 15105503
GO:0008379 thioredoxin peroxidase activity IDA 18606987
GO:0016209 antioxidant activity IEA --
genes like me logo Genes that share ontologies with PRDX1: view
genes like me logo Genes that share phenotypes with PRDX1: view

Animal Models for PRDX1 Gene

MGI Knock Outs for PRDX1:

Animal Model Products

  • Taconic Biosciences Mouse Models for PRDX1

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for PRDX1
  • Applied Biological Materials Clones for PRDX1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for PRDX1 Gene

Localization for PRDX1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PRDX1 Gene

Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for PRDX1 gene
Compartment Confidence
extracellular 5
nucleus 5
cytosol 5
mitochondrion 4
cytoskeleton 2
plasma membrane 1
peroxisome 1
endoplasmic reticulum 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for PRDX1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 22664934
GO:0005623 cell IEA --
GO:0005634 nucleus IDA 17603937
GO:0005737 cytoplasm IDA 17603937
GO:0005739 mitochondrion IEA --
genes like me logo Genes that share ontologies with PRDX1: view

Pathways & Interactions for PRDX1 Gene

genes like me logo Genes that share pathways with PRDX1: view

SIGNOR curated interactions for PRDX1 Gene

Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for PRDX1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001501 skeletal system development TAS 8089076
GO:0001895 retina homeostasis IEP 23580065
GO:0006979 response to oxidative stress IEA --
GO:0008283 cell proliferation IEA --
GO:0019430 removal of superoxide radicals IEA --
genes like me logo Genes that share ontologies with PRDX1: view

Drugs & Compounds for PRDX1 Gene

(11) Drugs for PRDX1 Gene - From: DrugBank, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Copper Approved Pharma Target 188
Zinc Approved Pharma Target 2359
Water Approved Pharma 0

(6) Additional Compounds for PRDX1 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with PRDX1: view

Transcripts for PRDX1 Gene

Unigene Clusters for PRDX1 Gene

Peroxiredoxin 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for PRDX1
  • Applied Biological Materials Clones for PRDX1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for PRDX1 Gene

ExUns: 1 ^ 2a · 2b · 2c ^ 3a · 3b · 3c ^ 4 ^ 5a · 5b · 5c ^ 6 ^ 7a · 7b · 7c ^ 8 ^ 9a · 9b · 9c
SP1: - - - - - - - - -
SP2: - - - - -
SP3: - - - - - -
SP4: - - - - - -
SP5: - - - -
SP6: - - -
SP7: - - - -
SP8: - - -
SP9: -
SP10: - - -

Relevant External Links for PRDX1 Gene

GeneLoc Exon Structure for
PRDX1
ECgene alternative splicing isoforms for
PRDX1

Expression for PRDX1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for PRDX1 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for PRDX1 Gene



Protein tissue co-expression partners for PRDX1 Gene

NURSA nuclear receptor signaling pathways regulating expression of PRDX1 Gene:

PRDX1

SOURCE GeneReport for Unigene cluster for PRDX1 Gene:

Hs.180909

Evidence on tissue expression from TISSUES for PRDX1 Gene

  • Nervous system(5)
  • Liver(4.9)
  • Lung(4.7)
  • Skin(4.7)
  • Pancreas(4.5)
  • Eye(4.4)
  • Intestine(3.9)
  • Kidney(3.9)
  • Muscle(3.4)
  • Bone(3.2)
  • Blood(3)
  • Heart(2.9)
  • Stomach(2.8)
  • Lymph node(2.7)
  • Spleen(2.7)
  • Thyroid gland(2.6)
  • Adrenal gland(2.2)
  • Gall bladder(2.2)
genes like me logo Genes that share expression patterns with PRDX1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for PRDX1 Gene

Orthologs for PRDX1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for PRDX1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia PRDX1 33 34
  • 99.66 (n)
cow
(Bos Taurus)
Mammalia PRDX1 33 34
  • 93.63 (n)
dog
(Canis familiaris)
Mammalia PRDX1 33 34
  • 93.3 (n)
-- 34
  • 91 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia PRDX1 34
  • 93 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia PRDX1 34
  • 92 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Prdx1 33
  • 91.29 (n)
mouse
(Mus musculus)
Mammalia Prdx1 33 16 34
  • 90.79 (n)
chicken
(Gallus gallus)
Aves PRDX1 33 34
  • 78.73 (n)
lizard
(Anolis carolinensis)
Reptilia PRDX1 34
  • 87 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC101731384 33
  • 76.21 (n)
Str.493 33
zebrafish
(Danio rerio)
Actinopterygii prdx1 33 34
  • 73.91 (n)
hmzehl0637 33
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.11565 33
fruit fly
(Drosophila melanogaster)
Insecta Jafrac1 35 34
  • 72 (a)
Jafrac2 35
  • 65 (a)
Prx5037 35
  • 61 (a)
CG6888 35 34
  • 56 (a)
worm
(Caenorhabditis elegans)
Secernentea F09E5.2 35
  • 74 (a)
prdx-2 34
  • 72 (a)
OneToMany
R07E5.2 35
  • 65 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes TSA1 34
  • 59 (a)
ManyToMany
TSA2 34
  • 58 (a)
ManyToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 60 (a)
OneToMany
Species where no ortholog for PRDX1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for PRDX1 Gene

ENSEMBL:
Gene Tree for PRDX1 (if available)
TreeFam:
Gene Tree for PRDX1 (if available)

Paralogs for PRDX1 Gene

Paralogs for PRDX1 Gene

(4) SIMAP similar genes for PRDX1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for PRDX1 Gene

genes like me logo Genes that share paralogs with PRDX1: view

Variants for PRDX1 Gene

Sequence variations from dbSNP and Humsavar for PRDX1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs12728919 Likely benign 45,510,577(+) GCCCA(A/G)TACTG intron-variant, utr-variant-3-prime
rs561153993 Uncertain significance 45,510,929(+) TGTCA(A/G)TATAA intron-variant, utr-variant-3-prime
rs886046382 Uncertain significance 45,510,816(+) CAGTC(A/G)CAGTG downstream-variant-500B, utr-variant-3-prime
rs886046383 Uncertain significance 45,510,861(+) CCCTC(-/AT)GTGTA downstream-variant-500B, utr-variant-3-prime
rs886046384 Uncertain significance 45,510,916(+) CTATA(A/T)CTACC downstream-variant-500B, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for PRDX1 Gene

Variant ID Type Subtype PubMed ID
esv1003037 CNV deletion 20482838
esv2665399 CNV deletion 23128226
esv2747819 CNV deletion 23290073
esv2992526 CNV deletion 24192839
esv3893512 CNV gain 25118596
nsv1119684 CNV deletion 24896259
nsv829726 CNV loss 17160897

Variation tolerance for PRDX1 Gene

Residual Variation Intolerance Score: 25.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.75; 15.86% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PRDX1 Gene

Human Gene Mutation Database (HGMD)
PRDX1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
PRDX1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PRDX1 Gene

Disorders for PRDX1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for PRDX1 Gene - From: HGMD, DISEASES, and Novoseek

Disorder Aliases PubMed IDs
anthrax disease
  • gas gangrene
cutaneous anthrax
  • anthrax, skin type
- elite association - COSMIC cancer census association via MalaCards
Search PRDX1 in MalaCards View complete list of genes associated with diseases

Relevant External Links for PRDX1

Genetic Association Database (GAD)
PRDX1
Human Genome Epidemiology (HuGE) Navigator
PRDX1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
PRDX1
genes like me logo Genes that share disorders with PRDX1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for PRDX1 Gene

Publications for PRDX1 Gene

  1. A human cDNA corresponding to a gene overexpressed during cell proliferation encodes a product sharing homology with amoebic and bacterial proteins. (PMID: 8496166) Prospéri MT … Goubin G (The Journal of biological chemistry 1993) 2 3 4 22 60
  2. Cloning and sequence analysis of candidate human natural killer-enhancing factor genes. (PMID: 8026862) Shau H … Kim A (Immunogenetics 1994) 3 4 22 60
  3. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PMID: 20877624) Hendrickson SL … O'Brien SJ (PloS one 2010) 3 45 60
  4. Protein engineering of the quaternary sulfiredoxin.peroxiredoxin enzyme.substrate complex reveals the molecular basis for cysteine sulfinic acid phosphorylation. (PMID: 19812042) Jönsson TJ … Lowther WT (The Journal of biological chemistry 2009) 3 4 60
  5. Prx1 enhances androgen receptor function in prostate cancer cells by increasing receptor affinity to dihydrotestosterone. (PMID: 19737972) Chhipa RR … Ip C (Molecular cancer research : MCR 2009) 3 22 60

Products for PRDX1 Gene

  • Addgene plasmids for PRDX1

Sources for PRDX1 Gene

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