Aliases for PRDM9 Gene
External Ids for PRDM9 Gene
Previous HGNC Symbols for PRDM9 Gene
Previous GeneCards Identifiers for PRDM9 Gene
The PR domain is a protein-protein interaction module of about 100 amino acids. PR domain-containing proteins, such as PRDM9, are often involved in transcriptional regulation (Jiang and Huang, 2000 [PubMed 10668202]).[supplied by OMIM, Mar 2008]
GeneCards Summary for PRDM9 Gene
PRDM9 (PR Domain Containing 9) is a Protein Coding gene. Among its related pathways are Gene Expression and Gene Expression. GO annotations related to this gene include nucleic acid binding and histone-lysine N-methyltransferase activity. An important paralog of this gene is ZNF169.
UniProtKB/Swiss-Prot for PRDM9 Gene
Histone methyltransferase that specifically trimethylates Lys-4 of histone H3 during meiotic prophase and is essential for proper meiotic progression. Does not have the ability to mono- and dimethylate Lys-4 of histone H3. H3 Lys-4 methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes during early meiotic prophase (By similarity).