Free for academic non-profit institutions. Other users need a Commercial license

Aliases for PRDM13 Gene

Aliases for PRDM13 Gene

  • PR Domain Containing 13 2 3
  • PR Domain-Containing Protein 13 3 4
  • PFM10 3 4
  • PR Domain Zinc Finger Protein 13 3
  • PR-Domain Zinc Finger Protein 13 3
  • PR-Domain Containing Protein 13 3
  • MU-MB-20.220 3
  • EC 2.1.1.- 4

External Ids for PRDM13 Gene

Previous GeneCards Identifiers for PRDM13 Gene

  • GC06P099922
  • GC06P100071
  • GC06P100100
  • GC06P100161
  • GC06P097494
  • GC06P100054

Summaries for PRDM13 Gene

GeneCards Summary for PRDM13 Gene

PRDM13 (PR Domain Containing 13) is a Protein Coding gene. Diseases associated with PRDM13 include medulloblastoma. GO annotations related to this gene include methyltransferase activity. An important paralog of this gene is PRDM16.

UniProtKB/Swiss-Prot for PRDM13 Gene

  • May be involved in transcriptional regulation

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRDM13 Gene

Genomics for PRDM13 Gene

Regulatory Elements for PRDM13 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for PRDM13 Gene

99,606,730 bp from pter
99,615,578 bp from pter
8,849 bases
Plus strand

Genomic View for PRDM13 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PRDM13 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRDM13 Gene

Proteins for PRDM13 Gene

  • Protein details for PRDM13 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    PR domain zinc finger protein 13
    Protein Accession:
    Secondary Accessions:
    • Q5TGC1
    • Q5TGC2

    Protein attributes for PRDM13 Gene

    707 amino acids
    Molecular mass:
    73981 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAG13448.1; Type=Miscellaneous discrepancy; Note=Non-canonical splice intron-exon junction.; Evidence={ECO:0000305}; Sequence=CAI19763.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI22063.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for PRDM13 Gene

Proteomics data for PRDM13 Gene at MOPED

Post-translational modifications for PRDM13 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PRDM13 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for PRDM13 Gene

Domains for PRDM13 Gene

Protein Domains for PRDM13 Gene

Suggested Antigen Peptide Sequences for PRDM13 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Q9H4Q3
  • Contains 1 SET domain.
  • Belongs to the class V-like SAM-binding methyltransferase superfamily.
  • Contains 4 C2H2-type zinc fingers.
genes like me logo Genes that share domains with PRDM13: view

No data available for Gene Families for PRDM13 Gene

Function for PRDM13 Gene

Molecular function for PRDM13 Gene

UniProtKB/Swiss-Prot Function: May be involved in transcriptional regulation

Enzyme Numbers (IUBMB) for PRDM13 Gene

Gene Ontology (GO) - Molecular Function for PRDM13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding IEA --
GO:0003682 chromatin binding IEA --
GO:0005515 protein binding --
GO:0008168 methyltransferase activity IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with PRDM13: view

Phenotypes for PRDM13 Gene

genes like me logo Genes that share phenotypes with PRDM13: view

Animal Model Products

CRISPR Products

miRNA for PRDM13 Gene

miRTarBase miRNAs that target PRDM13

No data available for Animal Models , Transcription Factor Targeting and HOMER Transcription for PRDM13 Gene

Localization for PRDM13 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PRDM13 Gene

Subcellular locations from

Jensen Localization Image for PRDM13 Gene COMPARTMENTS Subcellular localization image for PRDM13 gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for PRDM13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with PRDM13: view

Pathways for PRDM13 Gene

SuperPathways for PRDM13 Gene

No Data Available

Gene Ontology (GO) - Biological Process for PRDM13 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription from RNA polymerase II promoter IEA --
GO:0006351 transcription, DNA-templated IEA --
GO:0022008 neurogenesis IEA --
GO:0032259 methylation IEA --
genes like me logo Genes that share ontologies with PRDM13: view

No data available for Pathways by source for PRDM13 Gene

Transcripts for PRDM13 Gene

mRNA/cDNA for PRDM13 Gene

(3) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for PRDM13

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for PRDM13

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PRDM13 Gene

No ASD Table

Relevant External Links for PRDM13 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PRDM13 Gene

mRNA expression in normal human tissues for PRDM13 Gene

mRNA differential expression in normal tissues according to GTEx for PRDM13 Gene

This gene is overexpressed in Brain - Hypothalamus (14.2), Testis (12.4), and Brain - Spinal cord (cervical c-1) (7.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for PRDM13 Gene

SOURCE GeneReport for Unigene cluster for PRDM13 Gene Hs.287386

genes like me logo Genes that share expressions with PRDM13: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for PRDM13 Gene

Orthologs for PRDM13 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for PRDM13 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia PRDM13 35
  • 99.62 (n)
  • 99.43 (a)
PRDM13 36
  • 99 (a)
(Bos Taurus)
Mammalia PRDM13 35
  • 88.12 (n)
  • 90.77 (a)
PRDM13 36
  • 90 (a)
(Canis familiaris)
Mammalia PRDM13 36
  • 75 (a)
(Mus musculus)
Mammalia Prdm13 35
  • 82.19 (n)
  • 83.41 (a)
Prdm13 16
Prdm13 36
  • 75 (a)
(Monodelphis domestica)
Mammalia PRDM13 36
  • 72 (a)
(Ornithorhynchus anatinus)
Mammalia PRDM13 36
  • 86 (a)
(Rattus norvegicus)
Mammalia Prdm13 35
  • 83.1 (n)
  • 84.98 (a)
(Anolis carolinensis)
Reptilia PRDM13 36
  • 48 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia prdm13 35
  • 62.82 (n)
  • 65.54 (a)
(Danio rerio)
Actinopterygii prdm13 35
  • 64.17 (n)
  • 61.42 (a)
prdm13 36
  • 59 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG13296 36
  • 26 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 36
  • 12 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.1775 36
  • 15 (a)
Species with no ortholog for PRDM13:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for PRDM13 Gene

Gene Tree for PRDM13 (if available)
Gene Tree for PRDM13 (if available)

Paralogs for PRDM13 Gene

Paralogs for PRDM13 Gene

Selected SIMAP similar genes for PRDM13 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with PRDM13: view

Variants for PRDM13 Gene

Sequence variations from dbSNP and Humsavar for PRDM13 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs182790 -- 99,605,684(+) TGCCG(A/G)CAGAA upstream-variant-2KB
rs330837 -- 99,604,823(+) CAAAG(C/G)CTCCC upstream-variant-2KB
rs330838 -- 99,605,901(+) TTGCG(C/G)TGATT upstream-variant-2KB
rs330839 -- 99,606,369(+) AATAG(A/T)AGTTA upstream-variant-2KB
rs330840 -- 99,607,953(+) TTTGG(A/G)GGCGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PRDM13 Gene

Variant ID Type Subtype PubMed ID
nsv830741 CNV Gain 17160897

Relevant External Links for PRDM13 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PRDM13 Gene

Disorders for PRDM13 Gene

MalaCards: The human disease database

MalaCards: The human disease database. (1) Diseases for PRDM13 Gene including...

Search for PRDM13 Gene in MalaCards »

Relevant External Links for PRDM13

Genetic Association Database (GAD)
genes like me logo Genes that share disorders with PRDM13: view

No data available for UniProtKB/Swiss-Prot for PRDM13 Gene

Publications for PRDM13 Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  2. Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies. (PMID: 21102462) Elks C.E. … Murray A. (Nat. Genet. 2010) 3 48
  3. The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor. (PMID: 19336002) Zhou W. … Zhang L. (BMB Rep 2009) 3
  4. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3
  5. Novel tumor antigens identified by autologous antibody screening of childhood medulloblastoma cDNA libraries. (PMID: 12800201) Behrends U. … Mautner J. (Int. J. Cancer 2003) 3

Products for PRDM13 Gene

Sources for PRDM13 Gene

Back to Top