Aliases for PRCC Gene
External Ids for PRCC Gene
Previous GeneCards Identifiers for PRCC Gene
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010]
GeneCards Summary for PRCC Gene
PRCC (Papillary Renal Cell Carcinoma (Translocation-Associated)) is a Protein Coding gene. Diseases associated with PRCC include Renal Cell Carcinoma, Papillary and Renal Cell Carcinoma. Among its related pathways are Transcriptional misregulation in cancer and mRNA Splicing - Major Pathway.
UniProtKB/Swiss-Prot for PRCC Gene
May regulate cell cycle progression through interaction with MAD2L2.