Aliases for PRB2 Gene
External Ids for PRB2 Gene
Previous GeneCards Identifiers for PRB2 Gene
This gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature isoforms before secretion from the parotid glands. Multiple alleles of this gene exhibiting variations in the length of the tandem repeats, polymorphic cleavage sites and polymorphic stop codons have been identified. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. [provided by RefSeq, Oct 2015]
GeneCards Summary for PRB2 Gene
PRB2 (Proline-Rich Protein BstNI Subfamily 2) is a Protein Coding gene. Diseases associated with PRB2 include Diffuse Gastric Cancer. Among its related pathways are Salivary secretion. An important paralog of this gene is PRB1.