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Aliases for PRAMEF25 Gene

Aliases for PRAMEF25 Gene

  • PRAME Family Member 25 2 3 5

External Ids for PRAMEF25 Gene

Summaries for PRAMEF25 Gene

GeneCards Summary for PRAMEF25 Gene

PRAMEF25 (PRAME Family Member 25) is a Protein Coding gene. GO annotations related to this gene include retinoic acid receptor binding. An important paralog of this gene is PRAMEF26.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRAMEF25 Gene

Genomics for PRAMEF25 Gene

Regulatory Elements for PRAMEF25 Gene

Genomic Location for PRAMEF25 Gene

13,060,853 bp from pter
13,078,038 bp from pter
17,186 bases
Plus strand

Genomic View for PRAMEF25 Gene

Genes around PRAMEF25 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PRAMEF25 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PRAMEF25 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRAMEF25 Gene

Proteins for PRAMEF25 Gene

  • Protein details for PRAMEF25 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    PRAME family member 25
    Protein Accession:

    Protein attributes for PRAMEF25 Gene

    478 amino acids
    Molecular mass:
    55354 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PRAMEF25 Gene

Post-translational modifications for PRAMEF25 Gene

No Post-translational modifications

Other Protein References for PRAMEF25 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for PRAMEF25 Gene

Domains & Families for PRAMEF25 Gene

Gene Families for PRAMEF25 Gene

Protein Domains for PRAMEF25 Gene


Suggested Antigen Peptide Sequences for PRAMEF25 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the PRAME family.
  • Contains 6 LRR (leucine-rich) repeats.
  • Belongs to the PRAME family.
  • Contains 6 LRR (leucine-rich) repeats.
genes like me logo Genes that share domains with PRAMEF25: view

Function for PRAMEF25 Gene

Gene Ontology (GO) - Molecular Function for PRAMEF25 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042974 retinoic acid receptor binding IEA --
genes like me logo Genes that share ontologies with PRAMEF25: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRAMEF25 Gene

Localization for PRAMEF25 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for PRAMEF25 Gene

Pathways & Interactions for PRAMEF25 Gene

SuperPathways for PRAMEF25 Gene

No Data Available

Interacting Proteins for PRAMEF25 Gene

Gene Ontology (GO) - Biological Process for PRAMEF25 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008284 positive regulation of cell proliferation IEA --
GO:0043066 negative regulation of apoptotic process IEA --
GO:0045596 negative regulation of cell differentiation IEA --
GO:0045892 negative regulation of transcription, DNA-templated IEA --
GO:0048387 negative regulation of retinoic acid receptor signaling pathway IEA --
genes like me logo Genes that share ontologies with PRAMEF25: view

No data available for Pathways by source and SIGNOR curated interactions for PRAMEF25 Gene

Drugs & Compounds for PRAMEF25 Gene

No Compound Related Data Available

Transcripts for PRAMEF25 Gene

mRNA/cDNA for PRAMEF25 Gene

(1) REFSEQ mRNAs :
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PRAMEF25 Gene

No ASD Table

Relevant External Links for PRAMEF25 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PRAMEF25 Gene

mRNA expression in normal human tissues for PRAMEF25 Gene

Protein differential expression in normal tissues from HIPED for PRAMEF25 Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for PRAMEF25 Gene

Protein tissue co-expression partners for PRAMEF25 Gene

NURSA nuclear receptor signaling pathways regulating expression of PRAMEF25 Gene:

genes like me logo Genes that share expression patterns with PRAMEF25: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for PRAMEF25 Gene

Orthologs for PRAMEF25 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for PRAMEF25 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia PRAMEF11 34
  • 97.42 (n)
  • 93.93 (a)
-- 35
  • 76 (a)
-- 35
  • 77 (a)
(Mus musculus)
Mammalia Gm12790 35
  • 14 (a)
Species where no ortholog for PRAMEF25 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for PRAMEF25 Gene

Gene Tree for PRAMEF25 (if available)
Gene Tree for PRAMEF25 (if available)

Paralogs for PRAMEF25 Gene Pseudogenes for PRAMEF25 Gene

genes like me logo Genes that share paralogs with PRAMEF25: view

Variants for PRAMEF25 Gene

Sequence variations from dbSNP and Humsavar for PRAMEF25 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1806905 -- 13,076,004(-) TGGGC(A/G)TGGTA intron-variant
rs1810464 -- 13,075,464(+) GGTTG(C/T)CATAC intron-variant
rs1810465 -- 13,075,491(+) GGGGG(A/G)TTCAG intron-variant
rs1819130 -- 13,075,336(-) CTGTT(A/T)CATCC intron-variant
rs1964806 -- 13,077,447(-) TCCCT(A/C)ACTCT reference, synonymous-codon

Relevant External Links for PRAMEF25 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for PRAMEF25 Gene

Disorders for PRAMEF25 Gene

Relevant External Links for PRAMEF25

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for PRAMEF25 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PRAMEF25 Gene

Publications for PRAMEF25 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 65

Products for PRAMEF25 Gene

Sources for PRAMEF25 Gene

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