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Aliases for PRAMEF22 Gene

Aliases for PRAMEF22 Gene

  • PRAME Family Member 22 2 3
  • PRAMEF3L 3

External Ids for PRAMEF22 Gene

Previous GeneCards Identifiers for PRAMEF22 Gene

  • GC01P012957
  • GC01P012958
  • GC01P013035

Summaries for PRAMEF22 Gene

GeneCards Summary for PRAMEF22 Gene

PRAMEF22 (PRAME Family Member 22) is a Protein Coding gene. GO annotations related to this gene include retinoic acid receptor binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRAMEF22 Gene

Genomics for PRAMEF22 Gene

Regulatory Elements for PRAMEF22 Gene

Genomic Location for PRAMEF22 Gene

Start:
13,222,695 bp from pter
End:
13,226,133 bp from pter
Size:
3,439 bases
Orientation:
Minus strand

Genomic View for PRAMEF22 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PRAMEF22 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRAMEF22 Gene

Proteins for PRAMEF22 Gene

  • Protein details for PRAMEF22 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A3QJZ6-PRA22_HUMAN
    Recommended name:
    PRAME family member 22
    Protein Accession:
    A3QJZ6
    Secondary Accessions:
    • A6NMM3

    Protein attributes for PRAMEF22 Gene

    Size:
    481 amino acids
    Molecular mass:
    55489 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PRAMEF22 Gene

Proteomics data for PRAMEF22 Gene at MOPED

Post-translational modifications for PRAMEF22 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for PRAMEF22 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for PRAMEF22 Gene

Domains for PRAMEF22 Gene

Protein Domains for PRAMEF22 Gene

Suggested Antigen Peptide Sequences for PRAMEF22 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A3QJZ6

UniProtKB/Swiss-Prot:

PRA22_HUMAN :
  • A3QJZ6
Family:
  • Belongs to the PRAME family.
Similarity:
  • Contains 2 LRR (leucine-rich) repeats.
genes like me logo Genes that share domains with PRAMEF22: view

No data available for Gene Families for PRAMEF22 Gene

Function for PRAMEF22 Gene

Gene Ontology (GO) - Molecular Function for PRAMEF22 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042974 retinoic acid receptor binding IEA --
genes like me logo Genes that share ontologies with PRAMEF22: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for PRAMEF22 Gene

Localization for PRAMEF22 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for PRAMEF22 Gene COMPARTMENTS Subcellular localization image for PRAMEF22 gene
Compartment Confidence
extracellular 2
cytosol 1
mitochondrion 1
nucleus 1
peroxisome 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for PRAMEF22 Gene

Pathways for PRAMEF22 Gene

SuperPathways for PRAMEF22 Gene

No Data Available

Interacting Proteins for PRAMEF22 Gene

Gene Ontology (GO) - Biological Process for PRAMEF22 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008284 positive regulation of cell proliferation IEA --
GO:0043066 negative regulation of apoptotic process IEA --
GO:0045596 negative regulation of cell differentiation IEA --
GO:0045892 negative regulation of transcription, DNA-templated IEA --
GO:0048387 negative regulation of retinoic acid receptor signaling pathway IEA --
genes like me logo Genes that share ontologies with PRAMEF22: view

No data available for Pathways by source for PRAMEF22 Gene

Transcripts for PRAMEF22 Gene

mRNA/cDNA for PRAMEF22 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for PRAMEF22

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for PRAMEF22
  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PRAMEF22 Gene

No ASD Table

Relevant External Links for PRAMEF22 Gene

GeneLoc Exon Structure for
PRAMEF22
ECgene alternative splicing isoforms for
PRAMEF22

Expression for PRAMEF22 Gene

mRNA expression in normal human tissues for PRAMEF22 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for PRAMEF22 Gene

SOURCE GeneReport for Unigene cluster for PRAMEF22 Gene Hs.712522

genes like me logo Genes that share expressions with PRAMEF22: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for PRAMEF22 Gene

Orthologs for PRAMEF22 Gene

Evolution for PRAMEF22 Gene

ENSEMBL:
Gene Tree for PRAMEF22 (if available)
TreeFam:
Gene Tree for PRAMEF22 (if available)

No data available for Orthologs for PRAMEF22 Gene

Paralogs for PRAMEF22 Gene

genes like me logo Genes that share paralogs with PRAMEF22: view

No data available for Paralogs for PRAMEF22 Gene

Variants for PRAMEF22 Gene

Structural Variations from Database of Genomic Variants (DGV) for PRAMEF22 Gene

Variant ID Type Subtype PubMed ID
dgv20e1 CNV Complex 17122850
dgv21e1 CNV Complex 17122850
nsv428410 CNV Gain+Loss 18775914
dgv22e1 CNV Complex 17122850
dgv24e1 CNV Complex 17122850
dgv147n71 CNV Gain 21882294
dgv149n71 CNV Gain 21882294
nsv517190 CNV Gain+Loss 19592680
esv28644 CNV Gain+Loss 19812545
nsv8768 CNV Gain+Loss 18304495
esv32750 CNV Gain 17666407
nsv2965 CNV Loss 18451855
nsv7172 OTHER Inversion 18451855
dgv162n71 CNV Loss 21882294
nsv820528 CNV Deletion 20802225
dgv17e201 CNV Deletion 23290073
nsv819147 CNV Gain 19587683
nsv821616 CNV Gain 15273396
esv2675529 CNV Deletion 23128226
nsv508902 CNV Insertion 20534489
nsv510936 CNV Complex 20534489
esv1004322 CNV Gain 20482838
dgv14e199 CNV Deletion 23128226
nsv433183 CNV Loss 18776910
nsv871634 CNV Gain 21882294
dgv168n71 CNV Gain 21882294
nsv870885 CNV Loss 21882294
esv1000242 CNV Gain 20482838
esv25471 CNV Gain+Loss 19812545
nsv832981 CNV Loss 17160897

Relevant External Links for PRAMEF22 Gene

HapMap Linkage Disequilibrium report
PRAMEF22

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for PRAMEF22 Gene

Disorders for PRAMEF22 Gene

No disorders were found for PRAMEF22 Gene.

No data available for UniProtKB/Swiss-Prot for PRAMEF22 Gene

Publications for PRAMEF22 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  2. Duplication and positive selection among hominin-specific PRAME genes. (PMID: 16159394) Birtle Z. … Ponting C. (BMC Genomics 2005) 3

Products for PRAMEF22 Gene

Sources for PRAMEF22 Gene

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