Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



PRAMEF1 Gene

protein-coding   GIFtS: 43
GCID: GC01P012853

PRAME Family Member 1

  Search for PRAMEF1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
PRAME Family Member 11 2

External Ids:    HGNC: 288401   Entrez Gene: 651212   Ensembl: ENSG000001167217   UniProtKB: O955213   

Export aliases for PRAMEF1 gene to outside databases

Previous GC identifers: GC01P012786 GC01P012005


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for PRAMEF1 Gene:
This gene is a member of the PRAME (preferentially expressed antigen of melanoma) gene family which is expressed
in many cancers but may function in reproductive tissues during development. (provided by RefSeq, Sep 2011)

GeneCards Summary for PRAMEF1 Gene:
PRAMEF1 (PRAME family member 1) is a protein-coding gene. GO annotations related to this gene include retinoic acid receptor binding. An important paralog of this gene is PRAMEF19.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000001.10  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the PRAMEF1 gene promoter:
         HOXA9B   HOXA9   GR   E47   PPAR-alpha   PPAR-gamma1   PPAR-gamma2   GR-alpha   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPRAMEF1 promoter sequence
   Search Chromatin IP Primers for PRAMEF1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PRAMEF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p36.21   Ensembl cytogenetic band:  1p36.21   HGNC cytogenetic band: 1p36.21

PRAMEF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PRAMEF1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P012853:  view genomic region     (about GC identifiers)

Start:
12,851,546 bp from pter      End:
12,856,777 bp from pter
Size:
5,232 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: PRAM1_HUMAN, O95521 (See protein sequence)
Recommended Name: PRAME family member 1  
Size: 474 amino acids; 55162 Da
Secondary accessions: Q9UQP2

Explore the universe of human proteins at neXtProt for PRAMEF1: NX_O95521

Explore proteomics data for PRAMEF1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys99
  • Modification sites at PhosphoSitePlus

  • See PRAMEF1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_075389.1  
    ENSEMBL proteins: 
     ENSP00000332134   ENSP00000383616  

    PRAMEF1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for PRAMEF1
    GenScript Custom Purified and Recombinant Proteins Services for PRAMEF1
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for PRAMEF1

     
    Search eBioscience for Proteins for PRAMEF1 

    PRAMEF1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for PRAMEF1
    Search for Antibodies for PRAMEF1 at Abcam
    Cloud-Clone Corp. Antibodies for PRAMEF1
    Search ThermoFisher Antibodies for PRAMEF1
    LSBio Antibodies in human, mouse, rat for PRAMEF1

    PRAMEF1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for PRAMEF1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for PRAMEF1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for PRAMEF1
    Cloud-Clone Corp. CLIAs for PRAMEF1
    Search eBioscience for ELISAs for PRAMEF1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    2 InterPro protein domains:
     IPR026292 PRAME/Leu_rich_rep-con_p14
     IPR026271 PRAME_family

    Graphical View of Domain Structure for InterPro Entry O95521

    ProtoNet protein and cluster: O95521

    UniProtKB/Swiss-Prot: PRAM1_HUMAN, O95521
    Similarity: Belongs to the PRAME family
    Similarity: Contains 2 LRR (leucine-rich) repeats


    Find genes that share domains with PRAMEF1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0042974retinoic acid receptor binding IEA--
         
    Find genes that share ontologies with PRAMEF1           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PRAMEF1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PRAMEF1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PRAMEF1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PRAMEF1

    miRNA
    Products:
        
    miRTarBase miRNAs that target PRAMEF1:
    hsa-mir-335-5p (MIRT019126)

    Block miRNA regulation of human, mouse, rat PRAMEF1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate PRAMEF1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for PRAMEF1
    Predesigned siRNA for gene silencing in human, mouse, rat PRAMEF1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for PRAMEF1

    Clone
    Products:
         
    OriGene clones in human, mouse for PRAMEF1 (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PRAMEF1 (NM_023013)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PRAMEF1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRAMEF1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for PRAMEF1
    Browse ESI BIO Cell Lines and PureStem Progenitors for PRAMEF1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRAMEF1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    extracellular1
    peroxisome1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PRAMEF1
    Interactions:

        Search GeneGlobe Interaction Network for PRAMEF1

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for PRAMEF1 (ENSP000003321344) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRAMEF12ENSP000003503584STRING: ENSP00000350358
    TM2D1ENSP000003602224STRING: ENSP00000360222
    --ENSP000004088074STRING: ENSP00000408807
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008284positive regulation of cell proliferation IEA--
    GO:0043066negative regulation of apoptotic process IEA--
    GO:0045596negative regulation of cell differentiation IEA--
    GO:0045892negative regulation of transcription, DNA-templated IEA--
    GO:0048387negative regulation of retinoic acid receptor signaling pathway IEA--

    Find genes that share ontologies with PRAMEF1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PRAMEF1 (PRAM1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for PRAMEF1 gene: 
    NM_023013.3  

    Unigene Cluster for PRAMEF1:

    PRAME family member 1
    Hs.454859  [show with all ESTs]
    Unigene Representative Sequence: NM_023013
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000332296(uc001auj.2) ENST00000400814
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat PRAMEF1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate PRAMEF1
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for PRAMEF1
    Predesigned siRNA for gene silencing in human, mouse, rat PRAMEF1
    Clone
    Products:
         
    OriGene clones in human, mouse for PRAMEF1 (see all 4)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: PRAMEF1 (NM_023013)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PRAMEF1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRAMEF1
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for PRAMEF1
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat PRAMEF1
      QuantiTect SYBR Green Assays in human, mouse, rat PRAMEF1
      QuantiFast Probe-based Assays in human, mouse, rat PRAMEF1

    Additional mRNA sequence: 

    AK125568.1 AL049686.1 BC040902.1 BC144199.1 

    3 DOTS entries:

    DT.101975347  DT.97779824  DT.207193 

    4 AceView cDNA sequences:

    AL049686 NM_023013 BV183315 AK125568 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    PRAMEF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAACTTAAAG
    PRAMEF1 Expression
    About this image

    PRAMEF1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PRAMEF1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.454859
        Custom PCR Arrays for PRAMEF1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for PRAMEF1
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat PRAMEF1
    QuantiTect SYBR Green Assays in human, mouse, rat PRAMEF1
    QuantiFast Probe-based Assays in human, mouse, rat PRAMEF1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRAMEF1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus
      --

    ENSEMBL Gene Tree for PRAMEF1 (if available)
    TreeFam Gene Tree for PRAMEF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for PRAMEF1 gene
    PRAMEF131 2  PRAMEF21 2  PRAMEF192  PRAMEF102  PRAMEF32  PRAMEF202  PRAMEF262  PRAMEF182  
    PRAMEF212  PRAMEF122  PRAMEF152  PRAMEF222  PRAMEF42  PRAMEF92  PRAME2  LRRC14B2  
    PRAMEF142  PRAMEF72  PRAMEF82  ENSG000002398102  PRAMEF172  PRAMEF52  LRRC142  PRAMEF112  
    PRAMEF162  PRAMEF62  
    Selected SIMAP similar genes for PRAMEF1 using alignment to 3 protein entries:     PRAM1_HUMAN (see all proteins) (see all similar genes):
    PRAMEF13    PRAMEF2    PRAMEF14    PRAMEF10    PRAMEF17    PRAMEF22
    PRAMEF3    PRAMEF16    PRAMEF18    PRAMEF19    PRAMEF12    PRAMEF25
    PRAMEF24    PRAMEF8    PRAMEF7    PRAMEF15    PRAMEF20    PRAMEF21

    Find genes that share paralogs with PRAMEF1           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for PRAMEF1
    PGOHUM00000243902 PGOHUM00000244603


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for PRAMEF1 (see all 510)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2019580871,2
    Cuntested112871816(+) AGACTC/GTGACG 2 L V mis11Minor allele frequency- G:0.00EU 1309
    rs29821791,2
    C--12003355(-) TGTCCA/GTCATT 1 -- us2k10--------
    rs29821771,2
    C--12003488(-) TGTGAA/GCTGGA 1 -- us2k12Minor allele frequency- G:0.25NA 4
    rs744592951,2
    C--12006587(+) CTGGCG/AGGGCA 2 /A syn11Minor allele frequency- A:0.50NA 2
    rs617786081,2
    C--12006613(-) ACAAGT/GCCTGG 2 /D /A mis12Minor allele frequency- G:0.25NA 4
    rs754145941,2
    C--12849602(+) CTTTCA/C/TTGCTT 1 -- us2k11NA 2
    rs111219781,2
    C,A,H--12849604(+) ttcttG/Tcttgc 1 -- us2k10--------
    rs115856211,2
    C,H--12849608(+) tgcttG/Tcttgc 1 -- us2k10--------
    rs3711388501,2
    C--12855338(+) AAGAT-/AAAAAAA 1 -- int10--------
    rs115894041,2
    C,A,H--12867839(+) CTTCCC/TTCTTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PRAMEF1 (12851546 - 12856777 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for PRAMEF1 (see all 47):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2669351CNV Deletion23128226
    nsv471539CNV Duplication19718026
    nsv821559CNV Duplication20802225
    dgv15n67CNV Loss20364138
    nsv871956CNV Loss21882294
    dgv151n71CNV Loss21882294
    nsv870617CNV Loss21882294
    dgv13n67CNV Loss20364138
    dgv148n71CNV Loss21882294
    nsv871497CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PRAMEF1
    DNA2.0 Custom Variant and Variant Library Synthesis for PRAMEF1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for PRAMEF1 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with PRAMEF1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    2. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    3. Duplication and positive selection among hominin-specific PRAME genes. (PubMed id 16159394)1 Birtle Z....Ponting C. (BMC Genomics 2005)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    6. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 65121 HGNC: 28840 AceView: LOC65121 Ensembl:ENSG00000116721 euGenes: HUgn65121
    ECgene: PRAMEF1 H-InvDB: PRAMEF1

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for PRAMEF1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for PRAMEF1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for PRAMEF1 gene:
    Search GeneIP for patents involving PRAMEF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for PRAMEF1  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for PRAMEF1  
     OriGene qSTAR qPCR primer pairs in human, mouse for PRAMEF1   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     Browse OriGene ORF clones   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for PRAMEF1   OriGene Custom Protein Services for PRAMEF1  

     
     
     Block miRNA regulation of human, mouse, rat PRAMEF1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing PRAMEF1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PRAMEF1 Predesigned siRNA for gene silencing in human, mouse, rat PRAMEF1
     QuantiFast Probe-based Assays in human, mouse, rat PRAMEF1 QuantiTect SYBR Green Assays in human, mouse, rat PRAMEF1
     Custom PCR Arrays for PRAMEF1 Search Chromatin IP Primers for PRAMEF1
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat PRAMEF1 Search GeneGlobe Interaction Network for PRAMEF1
     Regulatory tfbs in PRAMEF1 promoter
     GenScript Custom Purified and Recombinant Proteins Services for PRAMEF1 GenScript cDNA clones with any tag delivered in your preferred vector for PRAMEF1
     GenScript Custom Assay Services for PRAMEF1 GenScript Custom overexpressing Cell Line Services for PRAMEF1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for PRAMEF1 (PRAM1)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Biologicals
     Novus Tissue Slides
     Search for Antibodies for PRAMEF1 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for PRAMEF1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for PRAMEF1
     Antibodies for PRAMEF1
     ELISAs for PRAMEF1
     CLIAs for PRAMEF1



     Browse ESI BIO Cell Lines and PureStem Progenitors for PRAMEF1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRAMEF1
     Browse SwitchGear 3'UTR luciferase reporter plasmids for PRAMEF1
     SwitchGear Promoter luciferase reporter plasmids for PRAMEF1
     Search ThermoFisher Antibodies for PRAMEF1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRAMEF1
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PRAMEF1
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for PRAMEF1
     LSBio Antibodies in human, mouse, rat for PRAMEF1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
     Search Addgene for plasmids for PRAMEF1
      Search eBioscience for proteins for PRAMEF1
      Search eBioscience for elisas for PRAMEF1
      eBioscience FlowRNA Probe Sets
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      PRAMEF1 gene at Home site.
    Version: 3.12.212 17 Sep 2014
    hostname: 356977-web1.xennexinc.com index build: 128 solr: 1.4