PRAME Gene
protein-coding GIFtS: 54
GCID: GC22M022890
|
|
preferentially expressed antigen in melanoma
(Previous symbol: MAPE)
| |
Aliases
for PRAME gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Preferentially Expressed Antigen In Melanoma1 2 | | Preferentially Expressed Antigen Of Melanoma2 3 | | MAPE1 2 3 5 | | OIP-42 3 | | OIP42 3 5 | | Cancer/Testis Antigen 1302 | | CT1301 2 | | Melanoma Antigen Preferentially Expressed In Tumors2 | | Opa-Interacting Protein 42 3 | | Opa-Interacting Protein OIP42 |
Export aliases for PRAME gene to outside databasesPrevious GC identifers: GC22M019588 GC22M021214 GC22M020673 GC22M005860 |
Summaries
for PRAME gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PRAME:
This gene encodes an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic Tlymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of otherCT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, this gene is also expressed inacute leukemias. Five alternatively spliced transcript variants encoding the same protein have been observed for thisgene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: PRAME_HUMAN, P78395Function: Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acidreceptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis
Gene Wiki entry for PRAME
|
Genomic Views
for PRAME gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PRAME gene promoter:
AML1a
Other transcription factors
Search SABiosciences Chromatin IP Primers for PRAME
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PRAME |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q11.22 Ensembl cytogenetic band: 22q11.22 HGNC cytogenetic band: 22q11.22PRAME Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22M022890: view genomic region
(about GC identifiers)
Start:
|
22,890,123 bp from pter |
End:
|
22,901,768 bp from pter |
Size:
|
11,646 bases |
Orientation:
|
minus strand |
|
Proteins
for PRAME gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PRAME_HUMAN, P78395 (See
protein sequence)Recommended Name: Melanoma antigen preferentially expressed in tumors Size: 509 amino acids; 57890 Da
Subunit: Interacts with RARA (via the ligand-binding domain); the interaction is direct and ligand (retinoicacid)-dependent. Interacts with EZH2; required to repress RAR signaling
Subcellular location: Nucleus (Probable). Cell membrane
Miscellaneous: Tumor antigen recognized by cytolytic T lymphocytes
Secondary accessions: B2R6Y7 O43481 Q8IXN8Explore the universe of human proteins at neXtProt for PRAME: NX_P78395
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P78395
PRAME Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_006106.1 NP_996836.1 NP_996837.1 NP_996838.1 NP_996839.1
ENSEMBL proteins: ENSP00000381728 ENSP00000384343 ENSP00000385198 ENSP00000407320 ENSP00000407121 ENSP00000412318 ENSP00000384058 ENSP00000399816 ENSP00000385091 ENSP00000445675 ENSP00000381726 ENSP00000445097 ENSP00000407342
Human Recombinant Protein Products for PRAME:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
PRAME for ontologies About GeneDecksing
PRAME Antibody Products:
Assay Products for PRAME: |
Protein
Domains /
Families
for PRAME gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PRAME for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P78395ProtoNet protein and cluster: P78395 1 Blocks protein family: IPB001611 Leucine-rich repeat signature
UniProtKB/Swiss-Prot: PRAME_HUMAN, P78395Similarity: Belongs to the PRAME familySimilarity: Contains 4 LRR (leucine-rich) repeats |
Function
for PRAME gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: PRAME_HUMAN, P78395Function: Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acidreceptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis Genatlas biochemistry entry for PRAME:preferentially expressed antigen in melanoma
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
PRAME for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PRAME (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PRAME (see all 5)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 5): PRAME (NM_006115) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PRAME | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRAME |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRAME |
|
Pathways & Interactions
for PRAME gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PRAME
5/7 Interacting proteins for PRAME (P783951, 2, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table
PRAME for ontologies About GeneDecksing
|
Drugs & Compounds
for PRAME gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for PRAME
Search CenterWatch for drugs/clinical trials and news about PRAME
|
Transcripts
for PRAME gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PRAME gene (5 alternative transcripts): NM_006115.3 NM_206953.1 NM_206954.1 NM_206955.1 NM_206956.1 Unigene Cluster for PRAME: Preferentially expressed antigen in melanoma Hs.30743 [show with all ESTs]Unigene Representative Sequence: BC02200816 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000398743(uc002zwf.3 uc010gtr.3 uc002zwi.3 uc002zwj.3)
ENST00000492657(uc002zwk.3) ENST00000405655 ENST00000402697 ENST00000439106
ENST00000438888 ENST00000420709 ENST00000476336 ENST00000485532 ENST00000406503
ENST00000442481 ENST00000403441 ENST00000543184 ENST00000398741(uc002zwg.3 uc002zwh.3)
ENST00000539862(uc011air.2) ENST00000424204
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PRAME (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PRAME (see all 5)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 5): PRAME (NM_006115) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PRAME | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRAME |
Additional cDNA sequence: AF025440.1 AK129783.1 AK302188.1 AK304593.1 AK312769.1 AK316395.1 BC014074.2 BC022008.1 BC039731.1 CR456549.1 U65011.1 19 DOTS entries: DT.314248 DT.97783168 DT.101964572 DT.40131245 DT.92444168 DT.92444174 DT.100757437 DT.97851491 DT.100825285 DT.100825299 DT.120677185 DT.92444178 DT.100825292 DT.91805738 DT.100825297 DT.120677343 DT.120677810 DT.120676911 DT.100825293 24/330 AceView cDNA sequences (see all 330): NM_206954 BM473529 BE893611 AA861253 BX371299 CR604772 BG035204 BG769045 AA496991 BQ439970 CD244596 BQ219052 CR456549 BQ070867 BQ230496 AW169285 BE891938 BE408826 AI744982 CR611321 BI825495 BE302526 BE898376 BU171925
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for PRAME (see all 8) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | · | 3c | · | 3d | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | · | 8c | ^ | 9 |
|---|
|
| SP1: | | | | | - | | - | | - | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | - | | | | | | - | | - | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | - | | - | | | | - | | - | | | | | | | | | | | | | | |
| SP4: | | | | | - | | - | | - | | | | - | | | | | | | | - | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | - | | - | | | | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for PRAME
|
Expression
for PRAME gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PRAME expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TAGGAGTTAA
About this image
See PRAME Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PRAME
SOURCE GeneReport for Unigene cluster: Hs.30743
UniProtKB/Swiss-Prot: PRAME_HUMAN, P78395Tissue specificity: Expressed in testis. Detected in samples of kidney, brain and skin
SABiosciences Custom PCR Arrays for PRAME
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PRAME
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat PRAME | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PRAME | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PRAME | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRAME |
Orthologs
for PRAME gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for PRAME (if available)
TreeFam Gene Tree for PRAME (if available) |
Paralogs
for PRAME gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PRAME gene
- PRAMEF192 PRAMEF102 PRAMEF32 PRAMEF202 LOC6453592 PRAMEF182 PRAMEF122 PRAMEF212
- PRAMEF152 PRAMEF222 PRAMEF42 PRAMEF22 PRAMEF132 PRAMEF92 LRRC14B2 PRAMEF142
- PRAMEF72 PRAMEF82 PRAMEF172 LRRC142 PRAMEF52 PRAMEF112 PRAMEF162 PRAMEF12
- PRAMEF62
18/26 SIMAP similar genes for PRAME using alignment to 8 protein entries: PRAME_HUMAN (see all proteins)
(see all similar genes):PRAMEF12 PRAMEF24 PRAMEF7 PRAMEF8 LOC645359 PRAMEF15
PRAMEF9 PRAMEF19 PRAMEF20 PRAMEF21 PRAMEF23 PRAMEF4
PRAMEF5 PRAMEF6 PRAMEF11 PRAMEF25 PRAMEF3 PRAMEF10
PRAME for paralogs About GeneDecksing
|
Genomic Variants
for PRAME gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PRAME (22890123 - 22901768 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 35 variations for PRAME
15/35 CNVs (see all 35): 90933 59061 34540 90934 5356 35989 9835 5175 90937 0334 35987 35996 53720 2019 90936 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PRAME |
|
Disorders
/ Diseases
for PRAME gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PRAME for disorders About GeneDecksing
OMIM gene information: 606021
OMIM disorders: --
20/36  diseases for PRAME (see all 36): About MalaCardsmelanoma acute leukemia leukemia diffuse large b-cell lymphoma
b-cell lymphomas testicular germ cell tumor soft tissue sarcoma germ cell tumor
myeloid leukemia hairy cell leukemia mantle cell lymphoma lymphoblastic leukemia
cervical squamous cell carcinoma acute promyelocytic leukemia squamous cell carcinoma acute lymphoblastic leukemia
chronic lymphocytic leukemia acute myeloid leukemia chronic myeloid leukemia lymphocytic leukemia
1 disease from the University of Copenhagen DISEASES database for PRAME:Leukemia 10/14 Novoseek disease relationships for PRAME gene (see all 14) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| minimal residual disease |
72.5 |
11 |
18950857 (2), 11298586 (2), 11943337 (1), 16860864 (1) (see all 7) |
| melanoma |
60.5 |
24 |
9753074 (2), 16707612 (2), 10682862 (2), 16179254 (1) (see all 14) |
| blast crisis |
53.9 |
3 |
17157168 (1), 17382387 (1) |
| acute leukemia |
53.8 |
7 |
16860864 (3), 16044453 (2), 9753074 (1), 12620290 (1) |
| myeloid leukemia chronic |
52.6 |
3 |
17382387 (2), 10682862 (1) |
| leukemia |
45.1 |
11 |
16978861 (2), 11298586 (2), 16681423 (2), 16044453 (1) (see all 8) |
| solid tumor |
36 |
3 |
16044453 (1), 16860864 (1), 18295331 (1) |
| tumors |
34.3 |
20 |
15240516 (3), 18709641 (3), 16044453 (2), 12419593 (2) (see all 11) |
| lymphoblastic leukemia acute |
27.7 |
1 |
12419593 (1) |
| cancer |
26.1 |
11 |
9740504 (2), 10741395 (2), 12620290 (1), 16179254 (1) (see all 8) |
Export disorders for PRAME gene to outside databases
|
Publications
for PRAME gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PRAME gene, integrated from 9 sources (see all 98):
(articles sorted by number of sources associating them with PRAME) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of an antigen that is recognized on a melanoma showing partial HLA loss by CTL expressing an NK inhibitory receptor. (PubMed id 9047241)1, 2, 3, 9 Ikeda H.... Coulie P.G. (1997)
- The human tumor antigen PRAME is a dominant repressor of retinoic acid receptor signaling. (PubMed id 16179254)1, 2, 9 Epping M.T....Bernards R. (2005)
- PRAME is a membrane and cytoplasmic protein aberrantly expressed in chronic lymphocytic leukemia and mantle cell lymphoma. (PubMed id 16620968)1, 2 Proto-Siqueira R.... Zago M.A. (2006)
- A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 3 Dunham I....O'Brien K.P. (1999)
- Using the yeast two-hybrid system to identify human epithelial cell proteins that bind gonococcal Opa proteins: intracellular gonococci bind pyruvate kinase via their Opa proteins and require host pyruvate for growth. (PubMed id 9466265)1, 2 Williams J.M.... Rest R.F. (1998)
- Aberrant hypomethylation of the cancer-testis antigen PRAME correlates with PRAME expression in acute myeloid leukemia. (PubMed id 18587578)1, 9 Ortmann C.A....Zeschnigk M. (2008)
- Epigenetic regulation of PRAME gene in chronic myeloid leukemia. (PubMed id 17382387)1, 9 Roman-Gomez J....Torres A. (2007)
- Expression patterns of WT1 and PRAME in acute myeloid leukemia patients and their usefulness for monitoring minimal residual disease. (PubMed id 18950857)1, 9 Qin Y....Huang X. (2009)
|
External Searches for PRAME gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PRAME gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PRAME gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PRAME gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for PRAME gene:
Search GeneIP for patents involving PRAME
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PRAME gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for PRAME | | OriGene shRNA RFP for PRAME | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PRAME | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PRAME | | | OriGene Protein Over-expression Lysate for PRAME | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PRAME | | OriGene 3'-UTR Clone for PRAME | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PRAME | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PRAME | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PRAME | | OriGene Custom Protein Services for PRAME | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PRAME | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PRAME | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PRAME | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PRAME | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PRAME | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PRAME |
| |
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| | | | Search Tocris compounds for PRAME |
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 | | | PRAME Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PRAME |
|  |  |  |  | | | | ThermoFisher Antibodies for PRAME |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PRAME |
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