Aliases for PRAC2 Gene
Aliases for PRAC2 Gene
External Ids for PRAC2 Gene
- HGNC: 30143
- Entrez Gene: 360205
- Ensembl: ENSG00000229637
- OMIM: 610787
- UniProtKB: D3DTV9
Previous HGNC Symbols for PRAC2 Gene
- C17orf93
- NCRNA00253
- HOXB13-AS1
- HOXB-AS5
Previous GeneCards Identifiers for PRAC2 Gene
- GC17U900086
- GC17P044155
- GC17P046806
- GC17P048725
Summaries for PRAC2 Gene
-
This gene is highly expressed in prostate, rectum, colon, and testis. This gene may produce a non-coding RNA or may encode a short protein that might localize to the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
GeneCards Summary for PRAC2 Gene
PRAC2 (Prostate Cancer Susceptibility Candidate 2) is a Protein Coding gene. Diseases associated with PRAC2 include Prostate Cancer Susceptibility.
No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRAC2 Gene
Genomics for PRAC2 Gene
Regulatory Elements for PRAC2 Gene
Enhancers for PRAC2 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around PRAC2 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for PRAC2 Gene
- Chromosome:
- 17
- Start:
- 48,720,809 bp from pter
- End:
- 48,724,758 bp from pter
- Size:
- 3,950 bases
- Orientation:
- Plus strand
Genomic View for PRAC2 Gene
Genes around PRAC2 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 17q21.32 by Ensembl
- 17q21.32 by Entrez Gene
- 17q21.32 by HGNC
PRAC2 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for PRAC2 Gene
Proteins for PRAC2 Gene
-
Protein details for PRAC2 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- D3DTV9-PRAC2_HUMAN
- Recommended name:
- Putative protein PRAC2
- Protein Accession:
- D3DTV9
Protein attributes for PRAC2 Gene
- Size:
- 90 amino acids
- Molecular mass:
- 10428 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for PRAC2 Gene
No Post-translational modifications
Other Protein References for PRAC2 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Search GeneTex for Antibodies for PRAC2
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for PRAC2
- Origene Custom Protein Services for PRAC2
- Search GeneTex for Proteins for PRAC2
Assay Products
No data available for DME Specific Peptides for PRAC2 Gene
Domains & Families for PRAC2 Gene
Protein Domains for PRAC2 Gene
- ProtoNet:
Graphical View of Domain Structure for InterPro Entry
No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PRAC2 Gene
Function for PRAC2 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for PRAC2
-
- Search ViGene Biosciences for PRAC2
CRISPR Products
- Browse CRISPR knockouts for PRAC2
miRNA Products
- Search ViGene Biosciences for PRAC2
Inhibitory RNA Products
- Search ViGene Biosciences for PRAC2
Clone Products
- VectorBuilder custom plasmid, inducible vectors for PRAC2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PRAC2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PRAC2 Gene
Localization for PRAC2 Gene
Subcellular locations from UniProtKB/Swiss-Prot for PRAC2 Gene
- Nucleus.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IEA | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
No data available for Subcellular locations from COMPARTMENTS for PRAC2 Gene
Transcripts for PRAC2 Gene
mRNA/cDNA for PRAC2 Gene
- (5) REFSEQ mRNAs :
- (24) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for PRAC2
miRNA Products
- Search ViGene Biosciences for PRAC2
Inhibitory RNA Products
- Search ViGene Biosciences for PRAC2
Clone Products
- VectorBuilder custom plasmid, inducible vectors for PRAC2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PRAC2
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for PRAC2 Gene
mRNA differential expression in normal tissues according to GTEx for PRAC2 Gene
This gene is overexpressed in Prostate (x18.9), Bladder (x7.9), Vagina (x6.2), and Colon - Transverse (x4.0).
NURSA nuclear receptor signaling pathways regulating expression of PRAC2 Gene:
PRAC2mRNA Expression by UniProt/SwissProt for PRAC2 Gene:
D3DTV9-PRAC2_HUMAN
Tissue specificity:
Highly expressed in prostate and testis. Also detected in placenta, muscle, colon, peripheral blood leukocytes and skin.
Primer Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for PRAC2 Gene
Orthologs for PRAC2 Gene
No data available for Orthologs for PRAC2 Gene
Paralogs for PRAC2 Gene
Pseudogenes.org Pseudogenes for PRAC2 Gene
No data available for Paralogs for PRAC2 Gene
Variants for PRAC2 Gene
| SNP ID | Clin | Chr 17 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000231825 | -- | 48,724,469(+) | CTTCT(C/T)CCATT | intron-variant, nc-transcript-variant, upstream-variant-2KB, reference, missense | |
| rs1000662927 | -- | 48,720,065(+) | GCTGG(G/T)CCCAC | upstream-variant-2KB | |
| rs1000832817 | -- | 48,724,735(+) | CACCA(C/G)TGGAA | intron-variant, upstream-variant-2KB, utr-variant-3-prime | |
| rs1000965281 | -- | 48,720,261(+) | GCCTG(A/G)GGGTC | upstream-variant-2KB | |
| rs1002156604 | -- | 48,721,412(+) | CCTCC(A/G)CCTCC | intron-variant, downstream-variant-500B, upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv2758694 | CNV | gain | 17122850 |
Relevant External Links for PRAC2 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- PRAC2
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for PRAC2 Gene
Disorders for PRAC2 Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| prostate cancer susceptibility |
|
|
Search PRAC2 in MalaCards
View complete list of genes associated with diseases
Relevant External Links for PRAC2
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- PRAC2
No data available for UniProtKB/Swiss-Prot and Genatlas for PRAC2 Gene
Publications for PRAC2 Gene
- PRAC2: a new gene expressed in human prostate and prostate cancer. (PMID: 12746837) Olsson P. … Pastan I. (Prostate 2003) 2 3 4 64
- DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 4 64
Products for PRAC2 Gene
- Browse R&D Systems for Antibodies
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- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
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- Browse cDNA Clones
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- Custom Antibody Services
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- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for PRAC2
- Origene Custom Protein Services for PRAC2
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- Browse CRISPR knockouts for PRAC2
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping cDNA ORF clone for PRAC2 in any vector
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- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cyagen custom Knockout/knockin (KOKI) mouse models for PRAC2
- VectorBuilder custom plasmid, inducible vectors for PRAC2
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for PRAC2
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for PRAC2 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer