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Aliases for PRAC2 Gene

Aliases for PRAC2 Gene

  • Prostate Cancer Susceptibility Candidate 2 2 3
  • Prostate, Rectum And Colon Expressed Gene Protein 2 3 4
  • HOXB Cluster Antisense RNA 5 2 3
  • HOXB13-AS1 3 4
  • NCRNA00253 3 4
  • C17orf93 3 4
  • HOXB-AS5 3 4
  • Prostate, Rectum And Colon Expressed Gene 2 Protein 3
  • HOXB Cluster Antisense RNA 5 (Non-Protein Coding) 2
  • HOXB13 Antisense RNA 1 (Non-Protein Coding) 2
  • Chromosome 17 Open Reading Frame 93 2
  • Prostate, Rectum And Colon 2 3
  • Small Nuclear Protein PRAC2 3
  • Non-Protein Coding RNA 253 2
  • Putative Protein PRCA2 3
  • Rectum And Colon 2 2
  • Prostate 2
  • HOXBAS5, 6

External Ids for PRAC2 Gene

Previous Symbols for PRAC2 Gene

  • C17orf93
  • NCRNA00253
  • HOXB13-AS1
  • HOXB-AS5

Summaries for PRAC2 Gene

Entrez Gene Summary for PRAC2 Gene

  • This gene is highly expressed in prostate, rectum, colon, and testis. This gene may produce a non-coding RNA or may encode a short protein that might localize to the nucleus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

GeneCards Summary for PRAC2 Gene

PRAC2 (Prostate Cancer Susceptibility Candidate 2) is a Protein Coding gene. Diseases associated with PRAC2 include prostate cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PRAC2 Gene

Genomics for PRAC2 Gene

Genomic Location for PRAC2 Gene

Start:
48,723,168 bp from pter
End:
48,724,758 bp from pter
Size:
1,591 bases
Orientation:
Plus strand

Genomic View for PRAC2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for PRAC2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PRAC2 Gene

No data available for Regulatory Elements for PRAC2 Gene

Proteins for PRAC2 Gene

  • Protein details for PRAC2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    D3DTV9-PRAC2_HUMAN
    Recommended name:
    Putative protein PRCA2
    Protein Accession:
    D3DTV9
    Secondary Accessions:

    Protein attributes for PRAC2 Gene

    Size:
    90 amino acids
    Molecular mass:
    10428 Da
    Quaternary structure:
    No Data Available

neXtProt entry for PRAC2 Gene

Proteomics data for PRAC2 Gene at MOPED

Post-translational modifications for PRAC2 Gene

No Post-translational modifications

Other Protein References for PRAC2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for PRAC2 Gene

Domains for PRAC2 Gene

Protein Domains for PRAC2 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PRAC2: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PRAC2 Gene

Function for PRAC2 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for PRAC2 Gene

Localization for PRAC2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for PRAC2 Gene

Gene Ontology (GO) - Cellular Components for PRAC2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with PRAC2: view

No data available for Subcellular locations from COMPARTMENTS for PRAC2 Gene

Pathways for PRAC2 Gene

SuperPathways for PRAC2 Gene

No Data Available

Interacting Proteins for PRAC2 Gene

Gene Ontology (GO) - Biological Process for PRAC2 Gene

None

No data available for Pathways by source for PRAC2 Gene

Transcripts for PRAC2 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for PRAC2 Gene

No ASD Table

Relevant External Links for PRAC2 Gene

GeneLoc Exon Structure for
PRAC2
ECgene alternative splicing isoforms for
PRAC2

Expression for PRAC2 Gene

mRNA expression in normal human tissues for PRAC2 Gene

mRNA differential expression in normal tissues according to GTEx for PRAC2 Gene

This gene is overexpressed in Prostate (18.9), Bladder (7.9), Vagina (6.2), and Colon - Transverse (4.0).

mRNA Expression by UniProt/SwissProt for PRAC2 Gene

D3DTV9-PRAC2_HUMAN
Tissue specificity: Highly expressed in prostate and testis. Also detected in placenta, muscle, colon, peripheral blood leukocytes and skin.
genes like me logo Genes that share expressions with PRAC2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Protein expression for PRAC2 Gene

Orthologs for PRAC2 Gene

Evolution for PRAC2 Gene

ENSEMBL:
Gene Tree for PRAC2 (if available)
TreeFam:
Gene Tree for PRAC2 (if available)

No data available for Orthologs for PRAC2 Gene

Paralogs for PRAC2 Gene

No data available for Paralogs for PRAC2 Gene

Variants for PRAC2 Gene

Sequence variations from dbSNP and Humsavar for PRAC2 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs1140951 -- 48,721,900(-) AATAA(A/G)AAAAC upstream-variant-2KB
rs188737845 -- 48,721,174(+) CATGT(C/G)GTCCC upstream-variant-2KB
rs542675142 -- 48,721,200(+) CTGGA(C/G)CCAGA upstream-variant-2KB

Relevant External Links for PRAC2 Gene

HapMap Linkage Disequilibrium report
PRAC2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for PRAC2 Gene

Disorders for PRAC2 Gene

(1) MalaCards Diseases for PRAC2 Gene

Search for PRAC2 Gene in MalaCards »
genes like me logo Genes that share disorders with PRAC2: view

No data available for UniProtKB/Swiss-Prot for PRAC2 Gene

Publications for PRAC2 Gene

  1. PRAC2: a new gene expressed in human prostate and prostate cancer. (PMID: 12746837) Olsson P. … Pastan I. (Prostate 2003) 2 3 4
  2. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 4

Products for PRAC2 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate PRAC2
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for PRAC2
    • Block miRNA regulation of PRAC2 using miScript Target Protectors

    Sources for PRAC2 Gene

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