Free for academic non-profit institutions. Other users need a Commercial license

Aliases for PQLC2L Gene

Aliases for PQLC2L Gene

  • PQ Loop Repeat Containing 2 Like 2 3
  • PQ-Loop Repeat-Containing Protein 2-Like 3 4
  • C3orf55 3 4
  • Putative Uncharacterized Protein PQLC2L 3
  • Chromosome 3 Open Reading Frame 55 2
  • PQ Loop Repeat Containing 2-Like 5

External Ids for PQLC2L Gene

Previous HGNC Symbols for PQLC2L Gene

  • C3orf55

Summaries for PQLC2L Gene

GeneCards Summary for PQLC2L Gene

PQLC2L (PQ Loop Repeat Containing 2 Like) is a Protein Coding gene. An important paralog of this gene is PQLC2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for PQLC2L Gene

Genomics for PQLC2L Gene

Regulatory Elements for PQLC2L Gene

Enhancers for PQLC2L Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around PQLC2L on UCSC Golden Path with GeneCards custom track

Promoters for PQLC2L Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for PQLC2L Gene

157,543,246 bp from pter
157,677,750 bp from pter
134,505 bases
Plus strand

Genomic View for PQLC2L Gene

Genes around PQLC2L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
PQLC2L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for PQLC2L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for PQLC2L Gene

Proteins for PQLC2L Gene

  • Protein details for PQLC2L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative uncharacterized protein PQLC2L
    Protein Accession:
    Secondary Accessions:
    • C9JP04
    • C9JXB5
    • Q8N6Q6

    Protein attributes for PQLC2L Gene

    135 amino acids
    Molecular mass:
    15626 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH29129.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305};

    Alternative splice isoforms for PQLC2L Gene


neXtProt entry for PQLC2L Gene

Post-translational modifications for PQLC2L Gene

No Post-translational modifications

No data available for DME Specific Peptides for PQLC2L Gene

Domains & Families for PQLC2L Gene

Protein Domains for PQLC2L Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with PQLC2L: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for PQLC2L Gene

Function for PQLC2L Gene

Gene Ontology (GO) - Molecular Function for PQLC2L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015181 arginine transmembrane transporter activity IBA --
GO:0015189 L-lysine transmembrane transporter activity IBA --
genes like me logo Genes that share ontologies with PQLC2L: view

Phenotypes for PQLC2L Gene

genes like me logo Genes that share phenotypes with PQLC2L: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for PQLC2L Gene

Localization for PQLC2L Gene

Gene Ontology (GO) - Cellular Components for PQLC2L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005765 lysosomal membrane IBA --
GO:0016021 integral component of membrane IBA --
genes like me logo Genes that share ontologies with PQLC2L: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for PQLC2L Gene

Pathways & Interactions for PQLC2L Gene

SuperPathways for PQLC2L Gene

No Data Available

Interacting Proteins for PQLC2L Gene

Gene Ontology (GO) - Biological Process for PQLC2L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903401 L-lysine transmembrane transport IEA --
GO:1903826 arginine transmembrane transport IEA --
genes like me logo Genes that share ontologies with PQLC2L: view

No data available for Pathways by source and SIGNOR curated interactions for PQLC2L Gene

Drugs & Compounds for PQLC2L Gene

No Compound Related Data Available

Transcripts for PQLC2L Gene

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for PQLC2L Gene

No ASD Table

Relevant External Links for PQLC2L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for PQLC2L Gene

mRNA expression in normal human tissues for PQLC2L Gene

Protein differential expression in normal tissues from HIPED for PQLC2L Gene

This gene is overexpressed in Spinal cord (29.3), Prostate (21.8), and Gallbladder (16.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for PQLC2L Gene

NURSA nuclear receptor signaling pathways regulating expression of PQLC2L Gene:

genes like me logo Genes that share expression patterns with PQLC2L: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for PQLC2L Gene

Orthologs for PQLC2L Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for PQLC2L Gene

Organism Taxonomy Gene Similarity Type Details
(Ornithorhynchus anatinus)
Mammalia C3orf55 35
  • 32 (a)
(Pan troglodytes)
Mammalia C3orf55 35
  • 94 (a)
(Gallus gallus)
Aves C3orf55 35
  • 7 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 12 (a)
-- 35
  • 24 (a)
(Caenorhabditis elegans)
Secernentea laat-1 35
  • 10 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 35
  • 9 (a)
-- 35
  • 8 (a)
RTC2 35
  • 9 (a)
Species where no ortholog for PQLC2L was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for PQLC2L Gene

Gene Tree for PQLC2L (if available)
Gene Tree for PQLC2L (if available)

Paralogs for PQLC2L Gene

Paralogs for PQLC2L Gene

genes like me logo Genes that share paralogs with PQLC2L: view

Variants for PQLC2L Gene

Sequence variations from dbSNP and Humsavar for PQLC2L Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs7616293 - 157,553,267(+) AAGTC(A/G/T)TGGGA nc-transcript-variant, reference, missense
rs868186 -- 157,626,824(-) TCCTG(C/T)CCTCT intron-variant
rs868552 -- 157,626,924(+) ATATA(C/T)GCTGT intron-variant
rs868553 -- 157,627,021(+) GGGAA(C/T)GTTCC intron-variant
rs937500 -- 157,626,516(-) TACAG(C/T)TTATT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for PQLC2L Gene

Variant ID Type Subtype PubMed ID
esv2726098 CNV deletion 23290073
nsv4081 CNV deletion 18451855
nsv829767 CNV loss 17160897

Variation tolerance for PQLC2L Gene

Gene Damage Index Score: 0.69; 14.63% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for PQLC2L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for PQLC2L Gene

Disorders for PQLC2L Gene

Relevant External Links for PQLC2L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for PQLC2L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for PQLC2L Gene

Publications for PQLC2L Gene

  1. Cystinosin, MPDU1, SWEETs and KDELR belong to a well-defined protein family with putative function of cargo receptors involved in vesicle trafficking. (PMID: 22363504) Saudek V. (PLoS ONE 2012) 2 3 65
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 65
  3. The DNA sequence, annotation and analysis of human chromosome 3. (PMID: 16641997) Muzny D.M. … Gibbs R.A. (Nature 2006) 4 65
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 65
  5. Creation of genome-wide protein expression libraries using random activation of gene expression. (PMID: 11329013) Harrington J.J. … Ducar M. (Nat. Biotechnol. 2001) 3 65

Products for PQLC2L Gene

Sources for PQLC2L Gene

Loading form....