Aliases for PPP6R3 Gene
External Ids for PPP6R3 Gene
Previous HGNC Symbols for PPP6R3 Gene
Previous GeneCards Identifiers for PPP6R3 Gene
Protein phosphatase regulatory subunits, such as SAPS3, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS3 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010]
GeneCards Summary for PPP6R3 Gene
PPP6R3 (Protein Phosphatase 6 Regulatory Subunit 3) is a Protein Coding gene. Diseases associated with PPP6R3 include Pseudosarcomatous Fibromatosis and Decubitus Ulcer. Among its related pathways are Vesicle-mediated transport and Transport to the Golgi and subsequent modification. GO annotations related to this gene include binding and protein phosphatase binding. An important paralog of this gene is PPP6R2.
UniProtKB/Swiss-Prot for PPP6R3 Gene
Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. May have an important role in maintaining immune self-tolerance.