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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PPP3R2 Gene

protein-coding   GIFtS: 57
GCID: GC09M104353

protein phosphatase 3, regulatory subunit B, beta

(Previous names: protein phosphatase 3 (formerly 2B), regulatory subunit...)
 Explore 6 diseases affiliated with
PPP3R2 via our new
 Human Malady Compendium 
Biological research products
for PPP3R2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Protein Phosphatase 3, Regulatory Subunit B, Beta1 2     Protein Phosphatase 2B Regulatory Subunit 22 3
PPP3RL1 2 3     Protein Phosphatase 3 Regulatory Subunit B Beta Isoform2 3
Protein Phosphatase 3 (Formerly 2B), Regulatory Subunit B (19kD), Beta Isoform
(Calcineurin B, Type II)1 2
     CBLP2 3
Protein Phosphatase 3 (Formerly 2B), Regulatory Subunit B, 19kDa, Beta Isoform
(Calcineurin B, Type II)1 2
     CNBII2 3
Protein Phosphatase 3 (Formerly 2B), Regulatory Subunit B, Beta Isoform1 2     Calcineurin B, Type II (19kDa)2
Calcineurin B-Like Protein2 3     Calcineurin Subunit B Type 22
Calcineurin BII2 3     PPP3R1-Like1

External Ids:    HGNC: 93181   Entrez Gene: 55352   Ensembl: ENSG000001883867   OMIM: 6138215   UniProtKB: Q96LZ33   

Export aliases for PPP3R2 gene to outside databases

Previous GC identifers: GC00U990278 GC09M096097 GC09M097811 GC09M099733 GC09M101433 GC09M103393 GC09M073954


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: CANB2_HUMAN, Q96LZ3
Function: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers
calcium sensitivity (By similarity)

Gene Wiki entry for PPP3R2


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NC_018920.1  NT_008470.19  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PPP3R2 gene promoter:
         Tal-1   AML1a   Lmo2   Nkx2-5   E47   Evi-1   AREB6   S8   FOXO1a   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPPP3R2 promoter sequence
   Search SABiosciences Chromatin IP Primers for PPP3R2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PPP3R2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q31.1   Ensembl cytogenetic band:  9q31.1   HGNC cytogenetic band: 9q31

PPP3R2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PPP3R2 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M104353:  view genomic region     (about GC identifiers)

Start:
104,353,897 bp from pter      End:
104,357,283 bp from pter
Size:
3,387 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CANB2_HUMAN, Q96LZ3 (See protein sequence)
Recommended Name: Calcineurin subunit B type 2  
Size: 170 amino acids; 19533 Da
Subunit: Composed of a catalytic subunit (A) and a regulatory subunit (B)
Miscellaneous: This protein has four functional calcium-binding sites (By similarity)
Sequence caution: Sequence=AAH30595.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=AAH66299.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=AAP57772.1;
Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAB71521.1; Type=Erroneous initiation;
Note=Translation N-terminally shortened; Sequence=CAH69961.1; Type=Erroneous initiation; Note=Translation N-terminally
shortened; Sequence=EAW58961.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: Q5VTR4 Q7Z4V8 Q8WYJ4

Explore the universe of human proteins at neXtProt for PPP3R2: NX_Q96LZ3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96LZ3

  • PPP3R2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_671709.1  
    ENSEMBL proteins: 
     ENSP00000363939  

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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    PPP3R2 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR001125 Recoverin
     IPR011992 EF-hand-like_dom
     IPR002048 EF_hand_Ca-bd
     IPR018247 EF_Hand_1_Ca_BS

    Graphical View of Domain Structure for InterPro Entry Q96LZ3

    ProtoNet protein and cluster: Q96LZ3

    1 Blocks protein family: IPB008080 Parvalbumin signature

    UniProtKB/Swiss-Prot: CANB2_HUMAN, Q96LZ3
    Similarity: Belongs to the calcineurin regulatory subunit family
    Similarity: Contains 4 EF-hand domains


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: CANB2_HUMAN, Q96LZ3
    Function: Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers
    calcium sensitivity (By similarity)

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    hsa-miR-2116* hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmidPPP3R2 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPP3R2

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
    GO:0005515protein binding ----


    PPP3R2 for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for PPP3R2:
     Increased S DNA content, incre  Increased cell death in HCT116  Increased cell size 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/37 super-pathways (see all 37About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Activation of cAMP-Dependent PKA
    Activation of cAMP-Dependent PKA1.00
    Activation of PKA through GPCR0.71
    cAMP Pathway0.77
    PKA Signaling0.56
    2PKC-Theta Pathway
    PKC-Theta Pathway1.00
    ITK and TCR Signaling0.54
    TCR Signaling0.68
    Fc-EpsilonRI Pathway0.42
    3ICos-ICosL Pathway in T-Helper Cell
    ICos-ICosL Pathway in T-Helper Cell1.00
    Calcium Mediated T-Cell Apoptosis0.31
    CD28 Signaling in T-Helper Cell0.66
    4NFAT and Cardiac Hypertrophy
    NFAT and Cardiac Hypertrophy1.00
    IGF1R Signaling0.37
    Signaling Involved in Cardiac Hypertrophy0.42
    5B cell receptor signaling pathway
    B cell receptor signaling pathway1.00
    PI3K Signaling in B-Lymphocyte0.35
    T cell receptor signaling pathway0.40

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    4 EMD Millipore Pathways for PPP3R2
        Neurophysiological process Glutamate regulation of Dopamine D1A receptor signaling
    Immune response CD16 signaling in NK cells
    Development Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis
    Signal transduction Activation of PKC via G-Protein coupled receptor

    5/32 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for PPP3R2 (see all 32)
        14-3-3 Induced Apoptosis
    Intracellular Calcium Signaling
    PI3K Signaling in B-Lymphocyte
    IL-2 Pathway
    ITK and TCR Signaling

    4 GeneGo (Thomson Reuters) Pathways for PPP3R2
        Signal transduction Activation of PKC via G-Protein coupled receptor
    Development Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis
    Immune response CD16 signaling in NK cells
    Neurophysiological process Glutamate regulation of Dopamine D1A receptor signaling

    3 BioSystems Pathways for PPP3R2 
        MAPK signaling pathway
    Alzheimers Disease
    Energy Metabolism

    1 PharmGKB Pathway for PPP3R2
        Tacrolimus/Cyclosporine Pathway, Pharmacodynamics

    5/15         Kegg Pathways  (Kegg details for PPP3R2) (see all 15):
        MAPK signaling pathway
    Calcium signaling pathway
    Oocyte meiosis
    Apoptosis
    Wnt signaling pathway


    PPP3R2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PPP3R2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/34 Interacting proteins for PPP3R2 (Q96LZ33 ENSP000003639394) via UniProtKB, MINT, STRING, and/or I2D (see all 34)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TBC1D10CQ8IV043, ENSP000003101934I2D: score=1 STRING: ENSP00000310193
    PLCG1ENSP000002440074STRING: ENSP00000244007
    PLCG2ENSP000003523364STRING: ENSP00000352336
    ANAPC1ENSP000003391094STRING: ENSP00000339109
    ANAPC10ENSP000003100714STRING: ENSP00000310071
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    PPP3R2 for compounds           About GeneDecksing

    EMD Millipore small molecules for PPP3R2:
    Small Molecule - inhibitor
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PPP3R2

    1 HMDB Compound for PPP3R2    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    1 DrugBank Compound for PPP3R2    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    CyclosporineCiclosporin (see all 3)59865-13-3targetinhibitor20674565 17016423 17139284

    2 Novoseek chemical compound relationships for PPP3R2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    calcium 46.6 16 17825054 (1), 19054707 (1), 15322881 (1), 17922773 (1) (see all 8)
    threonine 32 1 11481038 (1)

    Search CenterWatch for drugs/clinical trials and news about PPP3R2 / CANB2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PPP3R2 gene: 
    NM_147180.2  

    Unigene Cluster for PPP3R2:

    Protein phosphatase 3, regulatory subunit B, beta
    Hs.151167  [show with all ESTs]
    Unigene Representative Sequence: BC030595
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000374806(uc004bbr.3)

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    hsa-miR-2116* hsa-miR-590-3p
    SwitchGear 3'UTR luciferase reporter plasmidPPP3R2 3' UTR sequence
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PPP3R2
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    Additional cDNA sequence: 

    AF085237.1 AF145026.1 AF400667.1 AK057524.1 AK302547.1 AK310471.1 BC030595.2 BC066299.1 

    1 DOTS entry:

    DT.311643 

    24/57 AceView cDNA sequences (see all 57):

    AI221970 AI014984 BI829745 BC030595 AF145026 AA428462 AA909534 NM_147180 
    AA953895 CD359160 AA431190 AA431516 AI797296 AF085237 AF400667 BI559523 
    BI463408 BI830170 BG773361 AA429551 AA629305 BG720768 AK057524 AI123443 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PPP3R2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: GGTGTTAGGT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See PPP3R2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PPP3R2

    SOURCE GeneReport for Unigene cluster: Hs.151167

    UniProtKB/Swiss-Prot: CANB2_HUMAN, Q96LZ3
    Tissue specificity: Testis-specific

        SABiosciences Expression via Pathway-Focused PCR Array including PPP3R2: 
              VEGF Signaling in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPP3R2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for PPP3R2 gene from 4/23 species (see all 23)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    zebrafish
    (Danio rerio)
    Actinopterygii ppp3r1b6
    ppp3r1a6
    protein phosphatase 3 (formerly 2B), regulatory s1...
    protein phosphatase 3 (formerly 2B), regulatory s1...
    85(a)
    83(a)
    many ↔ many
    many ↔ many
    1(52066634-52100204)
    13(972098-992674)
    fruit fly
    (Drosophila melanogaster)
    Insecta CanB26
    CanB6
    Calcineurin B
    75(a)
    73(a)
    many ↔ many
    many ↔ many
    2R(3673517-3676558)
    X(5226532-5228482)
    worm
    (Caenorhabditis elegans)
    Secernentea cnb-16
    CalciNeurin B family member (cnb-1)
    74(a)
    1 → many
    V(11375724-11378039)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes CNB11 Cnb1p 57.48(n)
    58.97(a)
      853644   NP_012731.1 


    ENSEMBL Gene Tree for PPP3R2 (if available)
    TreeFam Gene Tree for PPP3R2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PPP3R2 gene
    CIB12  CIB32  PPP3R12  CHP22  WDR922  CIB42  TESC2  CIB22  
    CHP12  
    18/22 SIMAP similar genes for PPP3R2 using alignment to 1 protein entry:     CANB2_HUMAN(see all similar genes):
    PPP3R1    NCALD    CETN1    CETN2    CALM1    CALM2
    CALM3    NCS1    HPCAL1    CHP1    CALML3    CHP2
    DKFZp781K1922    LOC63928    TNNC2    CIB2    VSNL1    CIB3

    PPP3R2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/95 NCBI SNPs in PPP3R2 are shown (see all 95    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs735053011,2
    C,F,--104353412(+) GGTTTG/TCGTTA 2 -- int13Minor allele frequency- T:0.05WA 122
    rs1452438551,2
    --104353414(+) TTTGCA/GTTATC 2 -- int10--------
    rs1117271041,2
    --104353490(+) GTCTCG/ATCTAA 2 -- int11Minor allele frequency- A:0.50CSA 2
    rs1450852181,2
    --104353716(+) TTTGGG/TGTCAG 2 -- int10--------
    rs1389676111,2
    --104353728(+) AAGCCA/TGGTTC 2 -- int10--------
    rs1406980321,2
    --104353840(+) AGTGTG/TGTTAT 2 -- int10--------
    rs1459058121,2
    --104353909(+) ATAAAA/TGTTTA 2 -- ut31 int10--------
    rs625758541,2
    C,F,--104353940(+) TGTATA/GGAACT 2 -- ut31 int14Minor allele frequency- G:0.05NA WA 242
    rs1883856931,2
    --104354014(+) TGTGAC/TTCTTT 2 -- int1 ut310--------
    rs736595321,2
    C,--104354275(+) GTGTAC/TAAATA 2 -- int1 ut311Minor allele frequency- T:0.50WA 2

    HapMap Linkage Disequilibrium report for PPP3R2 (104353897 - 104357283 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for PPP3R2: --

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    PPP3R2 for disorders           About GeneDecksing

    OMIM gene information: 613821    OMIM disorders: --

    6 diseases for PPP3R2:    About MalaCards
    amyotrophic lateral sclerosis (als)    amyotrophic lateral sclerosis    lateral sclerosis    tuberculosis
    malaria    neuronitis

    Human Genome Epidemiology (HuGE) Navigator: PPP3R2 (8 documents)

    Export disorders for PPP3R2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PPP3R2 gene, integrated from 9 sources (see all 32):
    (articles sorted by number of sources associating them with PPP3R2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of a human regulatory subunit of protein phosphatase 3 gene (PPP3RL) expressed specifically in testis. (PubMed id 15865209)1, 2, 3, 9 Liu L....Yu L. (2005)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Comparison of the efficacy of tacrolimus and cyclospo rine A in a murine model of dinitrofluorobenzene-induced atopic dermatitis. (PubMed id 20674565)7 Yamashita H....Inagaki N. (2010)
    5. Are calcineurin genes associated with endurance pheno type traits? (PubMed id 20107831)1 He Z.H....Lucia A. (2010)
    6. Polymorphisms in the calcineurin genes are associated with the training responsiveness of cardiac phenotypes in Chinese young adults . (PubMed id 20593291)1 He Z.H....Lucia A. (2010)
    7. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)
    8. Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. (PubMed id 19156168)1 Need A.C....Goldstein D.B. (2009)
    9. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    10. Systematic association mapping identifies NELL1 as a novel IBD disease gene. (PubMed id 17684544)1 Franke A....Schreiber S. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 5535 HGNC: 9318 AceView: PPP3R2 Ensembl:ENSG00000188386 euGenes: HUgn5535
    ECgene: PPP3R2 Kegg: 5535 H-InvDB: PPP3R2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PPP3R2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PPP3R2 gene:
    Search GeneIP for patents involving PPP3R2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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