Aliases for PPP3CC Gene
- Protein Phosphatase 3 Catalytic Subunit Gamma 2 3 5
- Protein Phosphatase 3 (Formerly 2B), Catalytic Subunit, Gamma Isoform 2 3
- Protein Phosphatase 2B, Catalytic Subunit, Gamma Isoform 2 3
- Calmodulin-Dependent Calcineurin A Subunit Gamma Isoform 3 4
- Protein Phosphatase 3, Catalytic Subunit, Gamma Isozyme 2 3
- Calcineurin, Testis-Specific Catalytic Subunit 3 4
- CAM-PRP Catalytic Subunit 3 4
- EC 22.214.171.124 4 61
External Ids for PPP3CC Gene
Previous GeneCards Identifiers for PPP3CC Gene
Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
GeneCards Summary for PPP3CC Gene
PPP3CC (Protein Phosphatase 3 Catalytic Subunit Gamma) is a Protein Coding gene. Diseases associated with PPP3CC include Schizophrenia. Among its related pathways are ICos-ICosL Pathway in T-Helper Cell and NFAT and Cardiac Hypertrophy. GO annotations related to this gene include hydrolase activity and phosphoprotein phosphatase activity. An important paralog of this gene is PPP3CA.
UniProtKB/Swiss-Prot for PPP3CC Gene
Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.