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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PPP2R2D Gene

protein-coding   GIFtS: 52
GCID: GC10P133747

protein phosphatase 2, regulatory subunit B, delta

(Previous names: protein phosphatase 2, regulatory subunit B, delta isoform...)
 Explore 9 diseases affiliated with
PPP2R2D via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for PPP2R2D    

Aliases
for PPP2R2D gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Protein Phosphatase 2, Regulatory Subunit B, Delta1 2     PP2A Subunit B Isoform PR55-Delta2 3
MDS0261 2     PP2A Subunit B Isoform R2-Delta2 3
Protein Phosphatase 2, Regulatory Subunit B, Delta Isoform1 2     Serine/Threonine-Protein Phosphatase 2A 55 KDa Regulatory Subunit B Delta
Isoform2
PP2A Subunit B Isoform B55-Delta2 3     KIAA15413
PP2A Subunit B Isoform Delta2 3     

External Ids:    HGNC: 237321   Entrez Gene: 558442   Ensembl: ENSG000001754707   OMIM: 6139925   UniProtKB: Q66LE63   
ORGUL members:         
NONCODE:n409087    

Export aliases for PPP2R2D gene to outside databases

Previous GC identifers: GC10P133182 GC10P133597 GC10U900627 GC10P127299


Summaries
for PPP2R2D gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: 2ABD_HUMAN, Q66LE6
Function: B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling
mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell
cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via
interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits
modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to
a particular subcellular compartment (By similarity)

summary for PPP2R2D:
Protein ser/thr phosphatases are a group of enzymes that catalyze the removal of phosphate groups from
serine and/or threonine residues by the hydrolysis of phosphoric acid monoesters. They directly oppose the
actions of kinases and phosphorylases and therefore play an integral role in many signal transduction
pathways. There are two groups of serine/threonine phosphatases; phosphoprotein phosphatases (e.g. PP1,
calcineurin), which are sensitive to okadaic acid and metallo-phosphatases (e.g. PP2C), which require a
divalent cation, commonly Mg2+, for catalytic activity. Dephosphorylation, depending on the residue that the
phosphate group is removed from, can have a stimulatory or inhibitory effect on the target molecule. This
makes protein Ser/Thr phosphatases essential for many signal transduction pathways. Protein Ser/Thr
phosphatase are regulated by their subcellular localization and by inhibitor proteins, which are
subtype-specific.




Genomic Views
for PPP2R2D gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.1  NT_008818.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PPP2R2D gene promoter:
         POU2F1   POU2F1a   POU3F2   Pax-4a   YY1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: PPP2R2D promoter sequence
   Search SABiosciences Chromatin IP Primers for PPP2R2D

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PPP2R2D


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q26.3   Ensembl cytogenetic band:  10q26.3   HGNC cytogenetic band: 10q26.3

PPP2R2D Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PPP2R2D gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P133747:  view genomic region     (about GC identifiers)

Start:
 133,747,955 bp from pter      End:
 133,773,331 bp from pter
Size:
 25,377 bases      Orientation:
 plus strand

Proteins
for PPP2R2D gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: 2ABD_HUMAN, Q66LE6 (See protein sequence)
Recommended Name: Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform  
Size: 453 amino acids; 52042 Da
Subunit: PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a
65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits.
Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55,
R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell
signaling molecules. Interacts with ENSA (when phosphorylated at 'Ser-67') and ARPP19 (when phosphorylated at
'Ser-62'), leading to inhibit PP2A activity (By similarity)
Subcellular location: Cytoplasm (By similarity)
Sequence caution: Sequence=BAA96065.1; Type=Erroneous initiation; Sequence=CAI16703.1; Type=Erroneous gene model
prediction;
Secondary accessions: A8KAK0 Q5SQJ2 Q9P1Y7

Explore the universe of human proteins at neXtProt for PPP2R2D: NX_Q66LE6

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q66LE6

    • PPP2R2D Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_060931.2  
    ENSEMBL proteins: 
     ENSP00000399970   ENSP00000428418   ENSP00000406501  
    Reactome Protein details: Q66LE6
    Human Recombinant Protein Products: 
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    Novus Biologicals PPP2R2D Protein
    Novus Biologicals PPP2R2D Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Uscn

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000159protein phosphatase type 2A complex ISS--
    GO:0005654nucleoplasm ----
    GO:0005737cytoplasm IEA--
    GO:0005829cytosol ----


    PPP2R2D for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for PPP2R2D gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    PPP2R2D for domains           About GeneDecksing

    5 InterPro domains/families:
     IPR000009 PP2A_PR55
     IPR018067 PP2A_PR55_CS
     IPR001680 WD40_repeat
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry Q66LE6

    ProtoNet protein and cluster: Q66LE6

    1 Blocks protein family: IPB000009 Protein phosphatase 2A regulatory subunit PR55

    UniProtKB/Swiss-Prot: 2ABD_HUMAN, Q66LE6
    Similarity: Belongs to the phosphatase 2A regulatory subunit B family
    Similarity: Contains 7 WD repeats


    Function
    for PPP2R2D gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: 2ABD_HUMAN, Q66LE6
    Function: B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling
    mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell
    cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via
    interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits
    modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to
    a particular subcellular compartment (By similarity)

    miRNA
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate PPP2R2D:
    hsa-miR-548d-3p hsa-miR-548am hsa-miR-601 hsa-miR-133a hsa-miR-548x hsa-miR-133b
    SwitchGear 3'UTR luciferase reporter plasmid: PPP2R2D 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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    Clone
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    Cell Line
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008195phosphatidate phosphatase activity ----
    GO:0008601protein phosphatase type 2A regulator activity ISS--


    PPP2R2D for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for PPP2R2D:
     Decreased viability of wild-ty 


    Pathways & Interactions
    for PPP2R2D gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1M Phase
    		M Phase1.00
    		Mitotic M-M/G1 phases0.88
    2Cell Cycle
    		Cell Cycle1.00
    		Cell Cycle, Mitotic0.84
    3Hepatitis C
    		Hepatitis C1.00
    4mRNA surveillance pathway
    		mRNA surveillance pathway1.00
    5Tight junction
    		Tight junction1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    5/6        Reactome Pathways for PPP2R2D (see all 6)
        Mitotic Prophase
    Cell Cycle
    M Phase
    MASTL Facilitates Mitotic Progression
    Mitotic M-M/G1 phases


    4         Kegg Pathways  (Kegg details for PPP2R2D):
        mRNA surveillance pathway
    Tight junction
    Chagas disease (American trypanosomiasis)
    Hepatitis C


    PPP2R2D for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PPP2R2D

    5/138 Interacting proteins for PPP2R2D (Q66LE62, 3) via UniProtKB, MINT, STRING, and/or I2D (see all 138)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=6 
    HIST1H4BP628053I2D: score=6 
    HIST1H4CP628053I2D: score=6 
    HIST1H4DP628053I2D: score=6 
    HIST1H4EP628053I2D: score=6 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007067mitosis ISS--
    GO:0007165signal transduction IEA--
    GO:0010458exit from mitosis ISS--
    GO:0051301cell division IEA--


    PPP2R2D for ontologies           About GeneDecksing



    Drugs & Compounds
    for PPP2R2D gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for PPP2R2D available from Tocris Bioscience    About this table
    CompoundAction CAS #
    CantharidinProtein phosphatase 1 and 2A inhibitor[56-25-7]
    Okadaic acidProtein phosphatase 1 and 2A inhibitor[78111-17-8]
    Calyculin AProtein phosphatase 1 and 2A inhibitor[101932-71-2]
    Fostriecin sodium saltPotent PP2A and PP4 inhibitor[87860-39-7]
    Search CenterWatch for drugs/clinical trials and news about PPP2R2D / 2ABD 

    Transcripts
    for PPP2R2D gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for PPP2R2D gene (2 alternative transcripts): 
    NM_001003656.1  NM_018461.3  

    Unigene Cluster for PPP2R2D:

    Protein phosphatase 2, regulatory subunit B, delta
    Hs.380372  [show with all ESTs]
    Unigene Representative Sequence: NM_018461
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000455566(uc001lks.3) ENST00000482010(uc001lkr.3 uc001lkt.3 uc009yay.3)
    ENST00000517472 ENST00000490777 ENST00000470416 ENST00000472664 ENST00000422256


    miRNA
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate PPP2R2D:
    hsa-miR-548d-3p hsa-miR-548am hsa-miR-601 hsa-miR-133a hsa-miR-548x hsa-miR-133b
    SwitchGear 3'UTR luciferase reporter plasmid: PPP2R2D 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PPP2R2D (see all 7)
    OriGene shRNA RFP: PPP2R2D
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PPP2R2D
    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PPP2R2D 
    Primer
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    Additional cDNA sequence: 

    AF220046.1 AK000402.1 AK001483.1 AK293065.1 BC047379.1 BC058076.1 BC060885.1 BC072402.1 
    NR_033191.1 

    14 DOTS entries:

    DT.100784018  DT.101974483  DT.415970  DT.100784017  DT.101957321  DT.121243571  DT.435428  DT.95332606 
    DT.100784023  DT.40305239  DT.95150931  DT.95332625  DT.121639067  DT.436672 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for PPP2R2D (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b ^ 9a · 9b
    SP1:                                -     -     -                                                   
    SP2:        -                       -     -                                                         
    SP3:                                -     -                                                         
    SP4:        -                       -     -                                                         
    SP5:                                      -                                                         


    ECgene alternative splicing isoforms for PPP2R2D

    Expression
    for PPP2R2D gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PPP2R2D expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACCGGGTCCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image
    See PPP2R2D Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PPP2R2D

    SOURCE GeneReport for Unigene cluster: Hs.380372
        SABiosciences Custom PCR Arrays for PPP2R2D
    Primer
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    In Situ
    Assay Products:     
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    Orthologs
    for PPP2R2D gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for PPP2R2D gene from 7/25 species (see all 25)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves PPP2R2D1 protein phosphatase 2, regulatory subunit B, delta 84.41(n)
    95.79(a)    		   423970  NM_001006507.1  NP_001006507.1 
    lizard
    (Anolis carolinensis)    		 Reptilia PPP2R2D6
    		 --
    		 89(a)
    		 1 ↔ 1
    		 3(57792965-57819193)
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc:768871 zgc:76887 81.51(n)
    95.3(a)    		   405816  NM_212880.1  NP_998045.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta tws1 twins 67.64(n)
    78.25(a)    		   47877  NM_169329.1  NP_731451.1 
    worm
    (Caenorhabditis elegans)    		 Secernentea sur-66
    		 SUppressor of activated let-60 Ras family member (...
    		 57(a)
    		 1 → many
    		 I(9754111-9757889)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons ATB BETA1 Protein phosphatase 2A, regulatory subunit PR55 58.95(n)
    57.64(a)    		   838348  NM_179350.3  NP_849681.1 
    rice
    (Oryza sativa)    		 Liliopsida Os02g02242001 hypothetical protein 58.41(n)
    59.03(a)    		   4328769  NM_001052868.1  NP_001046333.1 


    ENSEMBL Gene Tree for PPP2R2D (if available)
    TreeFam Gene Tree for PPP2R2D (if available) 

    Paralogs
    for PPP2R2D gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PPP2R2D gene
    PPP2R2B2  PPP2R2C2  PPP2R2A2  
    3 SIMAP similar genes for PPP2R2D using alignment to 5 protein entries:     2ABD_HUMAN (see all proteins):
    PPP2R2A    PPP2R2C    PPP2R2B

    PPP2R2D for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for PPP2R2D
    PGOHUM00000237997


    Genomic Variants
    for PPP2R2D gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for PPP2R2D
         1 CNV: 71167
         3 Indels: 41384 33530 24387
    Human Gene Mutation Database (HGMD): PPP2R2D
    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PPP2R2D
    DNA2.0 Custom Variant and Variant Library Synthesis for PPP2R2D

    Disorders / Diseases
    for PPP2R2D gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    PPP2R2D for disorders           About GeneDecksing

    OMIM gene information: 613992    OMIM disorders: --

    9 diseases for PPP2R2D:    About MalaCards
    cerebral cavernous malformations    cavernous malformation    cerebral cavernous malformations 3    chagas disease
    hepatitis c    trypanosomiasis    cerebritis    twinning
    hepatitis


    Export disorders for PPP2R2D gene to outside databases

    Publications
    for PPP2R2D gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PPP2R2D gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with PPP2R2D)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10819331)1, 2, 3 Nagase T.... Ohara O. (2000)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (2004)
    5. Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)1 Naji S....Gerace L. (2012)
    6. Selective proteasomal degradation of the B'b subunit o f protein phosphatase 2A by the E3 ubiquitin ligase adaptor Kelch-like 15. (PubMed id 23135275)1 Oberg E.A....Strack S. (2012)
    7. Identification and functional analysis of variant hapl otypes in the 5'-flanking region of protein phosphatase 2A-Bd gene. (PubMed id 22539979)1 Chen H.F....Lin Y.C. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    10. Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation. (PubMed id 21081666)1 Greco T.M....Cristea I.M. (2011)

    External Searches for PPP2R2D gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing PPP2R2D gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55844 HGNC: 23732 Ensembl:ENSG00000175470 euGenes: HUgn55844 ECgene: PPP2R2D Kegg: 55844
    H-InvDB: PPP2R2D

    Other Databases showing PPP2R2D gene

    (According to HUGE)
    About This Section
    HUGE: KIAA1541

    Specialized Databases showing PPP2R2D gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PPP2R2D Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for PPP2R2D gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for PPP2R2D gene:
    Search GeneIP for patents involving PPP2R2D

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

     
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