Aliases for PPP2R2C Gene
- Protein Phosphatase 2 Regulatory Subunit B, Gamma 2 3 5
- Protein Phosphatase 2 (Formerly 2A), Regulatory Subunit B (PR 52), Gamma Isoform 2 3
- PP2A Subunit B Isoform Gamma 2 4
- IMYPNO1 3 4
- Serine/Threonine-Protein Phosphatase 2A 55 KDa Regulatory Subunit B Gamma Isoform 3
- Protein Phosphatase 2 (Formerly 2A), Regulatory Subunit B, Gamma Isoform 2
- Gamma Isoform Of Regulatory Subunit B55, Protein Phosphatase 2 3
- Phosphoprotein Phosphatase 2A BR Gamma Regulatory Chain 3
- Protein Phosphatase 2, Regulatory Subunit B, Gamma 2
- Protein Phosphatase 2A1 B Gamma Subunit 3
- PP2A, Subunit B, PR55-Gamma Isoform 3
External Ids for PPP2R2C Gene
Previous GeneCards Identifiers for PPP2R2C Gene
The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for PPP2R2C Gene
PPP2R2C (Protein Phosphatase 2 Regulatory Subunit B, Gamma) is a Protein Coding gene. Among its related pathways are CTLA4 Signaling and p70S6K Signaling. GO annotations related to this gene include protein phosphatase type 2A regulator activity. An important paralog of this gene is PPP2R2B.
UniProtKB/Swiss-Prot for PPP2R2C Gene
The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
Protein Ser/Thr phosphatases are a group of enzymes that catalyze the removal of phosphate groups from serine and/or threonine residues by hydrolysis of phosphoric acid monoesters. They oppose the action of kinases and phosphorylases and are involved in signal transduction.