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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PPP1R16B Gene

protein-coding   GIFtS: 50
GCID: GC20P037434

protein phosphatase 1, regulatory subunit 16B

(Previous names: protein phosphatase 1, regulatory (inhibitor) subunit 16B...)
  Search for PPP1R16B
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Biological research products
for PPP1R16B    

Aliases
for PPP1R16B gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Protein Phosphatase 1, Regulatory Subunit 16B1 2     CAAX Box Protein TIMAP2 3
ANKRD41 2 3     HTIMAP1
TIMAP1 2 5     TGF-Beta-Inhibited Membrane-Associated Protein2 3
KIAA08231 3 5     Ankyrin Repeat Domain Protein 42
Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 16B1 2     Protein Phosphatase 1 Regulatory Inhibitor Subunit 16B2
Ankyrin Repeat Domain-Containing Protein 42 3     

External Ids:    HGNC: 158501   Entrez Gene: 260512   Ensembl: ENSG000001014457   OMIM: 6132755   UniProtKB: Q96T493   

Export aliases for PPP1R16B gene to outside databases

Previous GC identifers: GC20P037162 GC20P038072 GC20P038119 GC20P036867 GC20P034171


Summaries
for PPP1R16B gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for PPP1R16B:
The protein encoded by this gene is membrane-associated and contains five ankyrin repeats, a protein
phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is
inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and
may act as a signaling molecule through interaction with protein phosphatase-1. Alternatively spliced transcript
variants encoding different isoforms have been identified in this gene.(provided by RefSeq, Feb 2010)

UniProtKB/Swiss-Prot: PP16B_HUMAN, Q96T49
Function: Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC)
barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection
against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the
dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a
downstream target for TGF-beta1 signaling cascade in endothelial cells




Genomic Views
for PPP1R16B gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000020.10  NC_018931.1  NT_011362.10  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PPP1R16B gene promoter:
         AREB6   Pax-5   Brachyury   Olf-1   STAT3   XBP-1   Tal-1beta   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: PPP1R16B promoter sequence
   Search SABiosciences Chromatin IP Primers for PPP1R16B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PPP1R16B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20q11.23   Ensembl cytogenetic band:  20q11.23   HGNC cytogenetic band: 20q11.23

PPP1R16B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PPP1R16B gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P037434:  view genomic region     (about GC identifiers)

Start:
 37,434,348 bp from pter      End:
 37,551,667 bp from pter
Size:
 117,320 bases      Orientation:
 plus strand

Proteins
for PPP1R16B gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: PP16B_HUMAN, Q96T49 (See protein sequence)
Recommended Name: Protein phosphatase 1 regulatory inhibitor subunit 16B precursor  
Size: 567 amino acids; 63551 Da
Subunit: Interacts with PPP1CA, PPP1CB and MSN. Interacts (via its fourth ankyrin repeat) with the mature dimeric form
of RPSA/LAMR1
Subcellular location: Cell membrane. Cell membrane; Lipid-anchor (Potential). Nucleus. Note=Co-localizes with
RPSA/LAMR1 in the cell membrane
Sequence caution: Sequence=BAA74846.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A2RRR6 O94912 Q9NQG4

Explore the universe of human proteins at neXtProt for PPP1R16B: NX_Q96T49

Post-translational modifications:

  • Phosphorylated by PKA and, after PKA priming, by GSK3B. Phosphorylation by GSK3B reduces its association with PP1C and
    • enhances PP1C activity. Dephosphorylation by its associated PP1C results in enhanced association with PP1C, but
    reduced PP1C activity (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96T49

    • PPP1R16B Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001166206.1  NP_056383.1  

    ENSEMBL proteins: 
     ENSP00000299824   ENSP00000403600   ENSP00000362428  

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    Uscn Proteins for PPP1R16B

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA18586956
    GO:0005886plasma membrane NAS12055102


    PPP1R16B for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for PPP1R16B gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    PPP1R16B for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR002110 Ankyrin_rpt
     IPR017417 Pase-1_reg_su_16AB_euk
     IPR020683 Ankyrin_rpt-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q96T49

    ProtoNet protein and cluster: Q96T49

    UniProtKB/Swiss-Prot: PP16B_HUMAN, Q96T49
    Similarity: Contains 5 ANK repeats


    Function
    for PPP1R16B gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: PP16B_HUMAN, Q96T49
    Function: Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC)
    barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection
    against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the
    dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a
    downstream target for TGF-beta1 signaling cascade in endothelial cells
    Induction: Inhibited by TGFB1

    miRNA
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    hsa-miR-642a hsa-miR-1224-3p hsa-miR-4267 hsa-miR-3142 hsa-miR-508-5p hsa-miR-3116 hsa-miR-4273 hsa-miR-525-3p
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI18586956
    GO:0019903protein phosphatase binding NAS12055102


    PPP1R16B for ontologies           About GeneDecksing


    5 GenomeRNAi human phenotypes for PPP1R16B:
     Decreased focal adhesion (FA)   Downregulation of NF-kappaB pa  Downregulation of NF-kappaB pa  Increased apoptosis 
     Wnt reporter downregulated 

    Animal Models:
         Mouse knock-out Ppp1r16btm1Ccb for PPP1R16B
         2 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Ppp1r16b):
     immune system  normal 

    PPP1R16B for phenotypes           About GeneDecksing


    Pathways & Interactions
    for PPP1R16B gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PPP1R16B

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007165signal transduction NAS12055102
    GO:0051489regulation of filopodium assembly ISS--


    PPP1R16B for ontologies           About GeneDecksing



    Drugs & Compounds
    for PPP1R16B gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PPP1R16B
    Search CenterWatch for drugs/clinical trials and news about PPP1R16B / PP16B 

    Transcripts
    for PPP1R16B gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for PPP1R16B gene (2 alternative transcripts): 
    NM_001172735.1  NM_015568.2  

    Unigene Cluster for PPP1R16B:

    Protein phosphatase 1, regulatory subunit 16B
    Hs.45719  [show with all ESTs]
    Unigene Representative Sequence: BC152467
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000299824(uc002xje.3) ENST00000438192 ENST00000468265 ENST00000463749
    ENST00000373331(uc010ggb.1 uc010ggc.3)

    miRNA
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    8/83 QIAGEN miScript miRNA Assays for microRNAs that regulate PPP1R16B (see all 83):
    hsa-miR-642a hsa-miR-1224-3p hsa-miR-4267 hsa-miR-3142 hsa-miR-508-5p hsa-miR-3116 hsa-miR-4273 hsa-miR-525-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Primer
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    Additional cDNA sequence: 

    AB020630.2 AB177855.1 AF362910.1 AK311244.1 BC026224.1 BC131801.1 BC152467.1 

    8 DOTS entries:

    DT.441178  DT.120825266  DT.100728218  DT.120825239  DT.91878182  DT.91936321  DT.92039791  DT.95131823 

    4 AceView cDNA sequences:

    BQ894802 BE748786 AK026900 BE748489 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for PPP1R16B    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14
    SP1:              -     -     -                                                                     
    SP2:                                                                    -                           
    SP3:                    -                                                                           
    SP4:              -                                                                                 


    ECgene alternative splicing isoforms for PPP1R16B

    Expression
    for PPP1R16B gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PPP1R16B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TCCCTGGAGT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    PPP1R16B expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    3 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    Gut TubeMidgutMidgut Endoderm CellsEndoderm
    Gut TubeMidgutGut Tube
    KidneyMetanephrosKidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 6 LifeMap Cells 
    NameCategory
    PureStem™ endothelial progenitor 30-MV2-12 (Embryonic Progenitor Cell)Blood, Endothelium
    PureStem™ endothelial Progenitor 30-SM2-3 (Embryonic Progenitor Cell)Blood, Endothelium
    PureStem™ endothelial progenitor 30-SM2-1 (Embryonic Progenitor Cell)Endothelium
    PureStem™ endothelial progenitor RP1-MV2-18 (Embryonic Progenitor Cell)Endothelium
    PureStem™ endothelial progenitor 30-MV2-14 (Embryonic Progenitor Cell)Endothelium
    Definitive endoderm-like cells (A scalable, suspensi...)

    See PPP1R16B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PPP1R16B

    SOURCE GeneReport for Unigene cluster: Hs.45719

    UniProtKB/Swiss-Prot: PP16B_HUMAN, Q96T49
    Tissue specificity: Highly expressed in vascular endothelium, CNS, lung, spleen, kidney and testis

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    In Situ
    Assay Products:     
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    Orthologs
    for PPP1R16B gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for PPP1R16B gene from 5/18 species (see all 18)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves PPP1R16B1 protein phosphatase 1, regulatory (inhibitor) subunit more 76.21(n)
    78.09(a)    		   419170  NM_001030851.1  NP_001026022.1 
    lizard
    (Anolis carolinensis)    		 Reptilia PPP1R16B6
    		 --
    		 75(a)
    		 1 ↔ 1
    		 4(140966496-141046546)
    zebrafish
    (Danio rerio)    		 Actinopterygii LOC7997711 protein phosphatase 1 regulatory inhibitor subunit more 64.02(n)
    62.98(a)    		   799771  XM_001340056.4  XP_001340092.4 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG68963   -- 42(a)   75D5   --
    worm
    (Caenorhabditis elegans)    		 Secernentea gfi-23 ankyrin motifs 52(a)   I(9748738-9751517)   --


    ENSEMBL Gene Tree for PPP1R16B (if available)
    TreeFam Gene Tree for PPP1R16B (if available) 

    Paralogs
    for PPP1R16B gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PPP1R16B gene
    PPP1R13B2  PPP1R272  TP53BP22  PPP1R12A2  PPP1R16A2  PPP1R12B2  NRARP2  PPP1R12C2  
    PPP1R13L2  
    10 SIMAP similar genes for PPP1R16B using alignment to 3 protein entries:     PP16B_HUMAN (see all proteins):
    KIAA0823    PPP1R12B    PPP1R27    NRARP    ANKRD54    IkBa
    PPP1R16A    PPP1R12A    DKFZp761E1322    MTPN

    PPP1R16B for paralogs           About GeneDecksing



    Genomic Variants
    for PPP1R16B gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1996 NCBI SNPs in PPP1R16B are shown (see all 1996)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 20 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs634043611,2
    		C--34205489(+) TTTTTC/TCCCAT 1 -- int10--------
    rs124813521,2
    		C,H--37432356(+) GCTTGT/GGCTAA 2 -- us2k14Minor allele frequency- G:0.00NS EA 418
    rs1148891671,2
    		F,--37432390(+) CCAAAG/ATCATG 2 -- us2k11Minor allele frequency- A:0.02WA 118
    rs1840682451,2
    		--37432435(+) ATAGTG/TTTAGC 2 -- us2k10--------
    rs1430728031,2
    		--37432514(+) GATATC/GCAGTT 2 -- us2k10--------
    rs1872462931,2
    		--37432530(+) AGCACA/CATTTT 2 -- us2k10--------
    rs1922713271,2
    		--37432537(+) TTTTTG/TGAAAA 2 -- us2k10--------
    rs799299271,2
    		F,--37432625(+) GGACTC/GTCAGT 2 -- us2k11Minor allele frequency- G:0.03WA 118
    rs114782841,2
    		C,--37432661(+) TCCTT-/ATACCC 2 -- us2k10--------
    rs1482314011,2
    		--37432665(+) TATACC/TCGTAC 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for PPP1R16B (37434348 - 37551667 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for PPP1R16B
         3 CNVs: 79188 79189 90548

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    Disorders / Diseases
    for PPP1R16B gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    PPP1R16B for disorders           About MalaCards

    PPP1R16B for disorders           About GeneDecksing

    OMIM gene information: 613275    OMIM disorders: --


    Export disorders for PPP1R16B gene to outside databases

    Publications
    for PPP1R16B gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PPP1R16B gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with PPP1R16B)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. TIMAP, a novel CAAX box protein regulated by TGF-beta1 and expressed in endothelial cells. (PubMed id 12055102)1, 2, 3 Cao W....Ballermann B.J. (2002)
    2. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)1, 2, 3 Nagase T....Ohara O. (1998)
    3. TIMAP is a positive regulator of pulmonary endothelial barrier function. (PubMed id 18586956)1, 2, 9 Csortos C....Verin A.D. (2008)
    4. The protein phosphatase-1 targeting subunit TIMAP reg ulates LAMR1 phosphorylation. (PubMed id 16263087)1, 2 Kim K....Ballermann B.J. (2005)
    5. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (2002)
    6. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
    7. Characterization of the effect of TIMAP phosphorylati on on its interaction with protein phosphatase 1. (PubMed id 21466834)1 Czikora I....Csortos C. (2011)
    8. TIMAP protects endothelial barrier from LPS-induced va scular leakage and is down-regulated by LPS. (PubMed id 21907835)1 Poirier C....Verin A.D. (2011)
    9. High-throughput mapping of a dynamic signaling network in mammalian cells. (PubMed id 15761153)1 Barrios-Rodiles M....Wrana J.L. (2005)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)

    External Searches for PPP1R16B gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing PPP1R16B gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26051 HGNC: 15850 AceView: PPP1R16B.1 Ensembl:ENSG00000101445 euGenes: HUgn26051
    ECgene: PPP1R16B H-InvDB: PPP1R16B

    Other Databases showing PPP1R16B gene

    (According to HUGE)
    About This Section
    HUGE: KIAA0823

    Specialized Databases showing PPP1R16B gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PPP1R16B Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for PPP1R16B Genetics and Cytogenetics in Oncology and Haematology

    Intellectual Property
    for PPP1R16B gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for PPP1R16B gene:
    Search GeneIP for patents involving PPP1R16B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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