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PPP1R16A Gene

protein-coding   GIFtS: 50
GCID: GC08P145703

Protein Phosphatase 1, Regulatory Subunit 16A

(Previous names: protein phosphatase 1, regulatory (inhibitor) subunit 16A)
  See PPP1R16A-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Protein Phosphatase 1, Regulatory Subunit 16A1 2
Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 16A1 2
Myosin Phosphatase-Targeting Subunit 32 3
MYPT32 3
Likley Ortholog Of Mouse Myosin Phosphatase Targeting Subunit 32
Protein Phosphatase 1 Regulatory Subunit 16A2

External Ids:    HGNC: 149411   Entrez Gene: 849882   Ensembl: ENSG000001609727   OMIM: 6091725   UniProtKB: Q96I343   

Export aliases for PPP1R16A gene to outside databases

Previous GC identifers: GC08P143416 GC08P145753 GC08P145308 GC08P145726 GC08P145692 GC08P145686 GC08P140835


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for PPP1R16A Gene:
PPP1R16A (protein phosphatase 1, regulatory subunit 16A) is a protein-coding gene. Diseases associated with PPP1R16A include papillary thyroid carcinoma. An important paralog of this gene is PPP1R13B.

UniProtKB/Swiss-Prot: PP16A_HUMAN, Q96I34
Function: Inhibits protein phosphatase 1 activity toward phosphorylase, myosin light chain and myosin substrates
(By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000008.10  NT_008046.17  NC_018919.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the PPP1R16A gene promoter:
         COUP-TF1   Sp1   p53   COUP   HNF-4alpha2   Nkx2-5   E47   COUP-TF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPPP1R16A promoter sequence
   Search Chromatin IP Primers for PPP1R16A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PPP1R16A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q24.3   Ensembl cytogenetic band:  8q24.3   HGNC cytogenetic band: 8q24.3

PPP1R16A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PPP1R16A gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P145703:  view genomic region     (about GC identifiers)

Start:
145,703,352 bp from pter      End:
145,727,504 bp from pter
Size:
24,153 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: PP16A_HUMAN, Q96I34 (See protein sequence)
Recommended Name: Protein phosphatase 1 regulatory subunit 16A precursor  
Size: 528 amino acids; 57811 Da
Subunit: Binds PP1
Sequence caution: Sequence=BAC03452.1; Type=Miscellaneous discrepancy; Note=Cloning artifact;
Secondary accessions: D3DWM5

Explore the universe of human proteins at neXtProt for PPP1R16A: NX_Q96I34

Explore proteomics data for PPP1R16A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See PPP1R16A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_116291.1  
    ENSEMBL proteins: 
     ENSP00000292539   ENSP00000433267   ENSP00000434324   ENSP00000391126  

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    Cloud-Clone Corp. Proteins for PPP1R16A

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    ANKRD: Ankyrin repeat domain containing
    PPP1R: Serine/threonine phosphatases / Protein phosphatase 1, regulatory subunits

    3 InterPro protein domains:
     IPR002110 Ankyrin_rpt
     IPR017417 Pase-1_reg_su_16AB_euk
     IPR020683 Ankyrin_rpt-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q96I34

    ProtoNet protein and cluster: Q96I34

    2 Blocks protein domains:
    IPB000408 Regulator of chromosome condensation
    IPB002110 Ankyrin repeat signature


    UniProtKB/Swiss-Prot: PP16A_HUMAN, Q96I34
    Similarity: Contains 5 ANK repeats


    Find genes that share domains with PPP1R16A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PP16A_HUMAN, Q96I34
    Function: Inhibits protein phosphatase 1 activity toward phosphorylase, myosin light chain and myosin substrates
    (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding ----
    GO:0005515protein binding IPI16169070
         
    Find genes that share ontologies with PPP1R16A           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for PPP1R16A:
     Increased cell death HMECs cel 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for PPP1R16A
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    miRNA
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    miRTarBase miRNAs that target PPP1R16A:
    hsa-mir-1 (MIRT024002)

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    1 qRT-PCR Assays for microRNA that regulate PPP1R16A:
    hsa-miR-374a*
    SwitchGear 3'UTR luciferase reporter plasmidPPP1R16A 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPP1R16A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    PP16A_HUMAN, Q96I34: Cell membrane; Lipid-anchor (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    nucleus3
    cytosol2
    cytoskeleton1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--

    Find genes that share ontologies with PPP1R16A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for PPP1R16A About   (see all 8)  
    See pathways by source

    SuperPathContained pathways About
    1Activation of cAMP-Dependent PKA
    Activation of cAMP-Dependent PKA0.77
    Activation of PKA through GPCR0.71
    cAMP Pathway0.77
    PKA Signaling0.56
    2Beta-Adrenergic Signaling
    Beta-Adrenergic Signaling0.37
    Insulin Receptor Pathway0.37
    Erythropoietin Pathway0.37
    CDK5 Pathway0.36
    3PEDF Induced Signaling
    IL-6 Pathway0.61
    4ERK Signaling
    ERK Signaling0.61
    5Apoptotic Pathways in Synovial Fibroblasts
    eIF2 Pathway0.60

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for PPP1R16A (see all 14)
        Activation of PKA through GPCR
    PKA Signaling
    eIF2 Pathway
    CDK5 Pathway
    Breast Cancer Regulation by Stathmin1



        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for PPP1R16A
    Interactions:

        GeneGlobe Interaction Network for PPP1R16A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    Selected Interacting proteins for PPP1R16A (Q96I341, 2, 3 ENSP000002925394) via UniProtKB, MINT, STRING, and/or I2D (see all 32)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PUF60Q9UHX11, 2, 3, ENSP000003220164EBI-710402,EBI-1053259 MINT-65190 I2D: score=5 STRING: ENSP00000322016
    IDO1P149022, 3MINT-65182 I2D: score=6 
    DDX27Q96GQ72, 3MINT-65186 I2D: score=5 
    FSD1Q9BTV52, 3MINT-65188 I2D: score=5 
    RGMAQ96B862, 3MINT-65185 I2D: score=5 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007010cytoskeleton organization ----

    Find genes that share ontologies with PPP1R16A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for PPP1R16A (PP16A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for PPP1R16A gene: 
    NM_032902.5  

    Unigene Cluster for PPP1R16A:

    Protein phosphatase 1, regulatory subunit 16A
    Hs.521937  [show with all ESTs]
    Unigene Representative Sequence: AK090471
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000526183 ENST00000529283 ENST00000526643 ENST00000533088 ENST00000292539(uc003zdd.3 uc003zdf.3)
    ENST00000529009 ENST00000533829 ENST00000532806 ENST00000526564 ENST00000528430
    ENST00000435887
    miRNA
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    1 qRT-PCR Assays for microRNA that regulate PPP1R16A:
    hsa-miR-374a*
    SwitchGear 3'UTR luciferase reporter plasmidPPP1R16A 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat PPP1R16A
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    GenScript: all cDNA clones in your preferred vector: PPP1R16A (NM_032902)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PPP1R16A
    Primer
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    OriGene qPCR primer pairs and template standards for PPP1R16A
    OriGene qSTAR qPCR primer pairs in human, mouse for PPP1R16A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat PPP1R16A
      QuantiTect SYBR Green Assays in human, mouse, rat PPP1R16A
      QuantiFast Probe-based Assays in human, mouse, rat PPP1R16A

    Additional mRNA sequence: 

    AK090471.1 AK126743.1 BC007854.2 BC015896.1 BC049841.1 BC053506.1 BT006845.1 

    13 DOTS entries:

    DT.214151  DT.91748667  DT.100796229  DT.75166300  DT.95233869  DT.95233872  DT.100697743  DT.121491806 
    DT.121491835  DT.65286443  DT.100796228  DT.97813543  DT.97839681 

    Selected AceView cDNA sequences (see all 300):

    AI673688 AI632072 NM_032902 BM757584 BQ067640 BM766464 BM743309 BM758944 
    BM758887 BM762702 AI274022 BM757654 BI760477 BQ447042 BU727570 BM758602 
    BM785006 BM762871 BM764329 BU537953 AI801012 BM758078 AW025120 BM758347 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    PPP1R16A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGGGGCCCT
    PPP1R16A Expression
    About this image

    PPP1R16A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    PPP1R16A Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.521937
        Custom PCR Arrays for PPP1R16A
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for PPP1R16A gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ppp1r16a1 , 5 protein phosphatase 1, regulatory (inhibitor) subunit more1, 5 82.19(n)1
    82.63(a)1
      15 (36.25 cM)5
    730621  NM_033371.21  NP_203535.11 
     766716155 
    lizard
    (Anolis carolinensis)
    Reptilia PPP1R16A6
    protein phosphatase 1, regulatory subunit 16A
    68(a)
    1 ↔ 1
    AAWZ02036392(511-24244)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia ppp1r16a1 protein phosphatase 1, regulatory subunit 16A 65.97(n)
    60.99(a)
      779806  NM_001078885.1  NP_001072353.1 
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-9l5.31 si:dkey-9l5.3 57.69(n)
    58.08(a)
      794494  XM_001334437.2  XP_001334473.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG68963   -- 42(a)   75D5   --
    worm
    (Caenorhabditis elegans)
    Secernentea gfi-21 , 3 ankyrin motifs3
    gfi-21
    49(a)3
    49.56(n)1
    48.68(a)1
      I(9748738-9751517)3
    1728251  NM_060186.31  NP_492587.11 


    ENSEMBL Gene Tree for PPP1R16A (if available)
    TreeFam Gene Tree for PPP1R16A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for PPP1R16A gene
    PPP1R13B2  PPP1R16B2  PPP1R12B2  PPP1R12A2  TP53BP22  PPP1R12C2  PPP1R13L2  
    1 SIMAP similar gene for PPP1R16A using alignment to 3 protein entries:     PP16A_HUMAN (see all proteins):
    PPP1R16B

    Find genes that share paralogs with PPP1R16A           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for PPP1R16A (see all 228)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs775937761,2
    C,F--145720213(+) GAGGGA/CGGGCT 1 -- us2k11Minor allele frequency- C:0.06EA 120
    rs38083711,2
    C--145720295(-) GGCAGG/AAGAGC 1 -- us2k13Minor allele frequency- A:0.02EA NA 1496
    rs1888887641,2
    --145720354(+) AGCCTA/GGGCAG 1 -- us2k10--------
    rs1917872821,2
    --145720486(+) AGCCAC/GGTCAG 1 -- us2k10--------
    rs132768621,2
    C,F,H--145720682(+) GGGGCA/GTTCTA 1 -- us2k112Minor allele frequency- G:0.06NS NA 1084
    rs1125796941,2
    C--145720705(+) TAGAAGT/-GTCCA 1 -- us2k11Minor allele frequency- -:0.50CSA 2
    rs1444611371,2
    --145720799(+) GAGCAC/TGGAGT 1 -- us2k10--------
    rs109027821,2
    C,A,H--145720870(+) CTGGAA/GTGCAG 1 -- us2k15Minor allele frequency- G:0.07NA 14
    rs1838681671,2
    --145720885(+) GTGATC/GTTGGC 1 -- us2k10--------
    rs1450951101,2
    --145721007(+) GCAGAA/GATGGG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PPP1R16A (145703352 - 145727504 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for PPP1R16A (see all 27):    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv907n27CNV Loss19166990
    dgv7966n71CNV Loss21882294
    dgv7977n71CNV Loss21882294
    dgv7976n71CNV Loss21882294
    dgv7978n71CNV Loss21882294
    dgv7983n71CNV Loss21882294
    dgv7982n71CNV Loss21882294
    nsv891911CNV Loss21882294
    nsv891846CNV Loss21882294
    nsv891817CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing PPP1R16A
    DNA2.0 Custom Variant and Variant Library Synthesis for PPP1R16A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609172    OMIM disorders: --

    1 disease for PPP1R16A:    
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    papillary thyroid carcinoma


    Find genes that share disorders with PPP1R16A           About GenesLikeMe


    Export disorders for PPP1R16A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PPP1R16A gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with PPP1R16A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    2. Regulator-driven functional diversification of protein phosphatase-1 in eukaryotic evolution. (PubMed id 11948623)1, 3 Ceulemans H.... Bollen M. (Bioessays 2002)
    3. Protein phosphatase 1I^ isoforms linked interactions in the brain. (PubMed id 23080069)1 Esteves S.L....da Cruz e Silva E.F. (J. Mol. Neurosci. 2013)
    4. Protein phosphatase 1I+ interacting proteins in the human brain. (PubMed id 22321011)1 Esteves S.L....da Cruz e Silva E.F. (OMICS 2012)
    5. Differential expression of a set of genes in follicular and classic variants of papillary thyroid carcinoma. (PubMed id 21509594)1 Igci Y.Z....Demiryurek A.T. (Endocr. Pathol. 2011)
    6. Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes. (PubMed id 19019082)1 Pridgeon J.W....Chin L.S. (FEBS J. 2009)
    7. An empirical framework for binary interactome mapping. (PubMed id 19060904)1 Venkatesan K....Vidal M. (Nat. Methods 2009)
    8. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    9. Phosphorylation of myosin phosphatase targeting subunit 3 (MYPT3) and regulation of protein phosphatase 1 by protein kinase A. (PubMed id 16920702)1 Yong J....Leung T. (J. Biol. Chem. 2006)
    10. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)1 Stelzl U.... Wanker E.E. (Cell 2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 84988 HGNC: 14941 AceView: PPP1R16A Ensembl:ENSG00000160972 euGenes: HUgn84988
    ECgene: PPP1R16A H-InvDB: PPP1R16A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for PPP1R16A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for PPP1R16A gene:
    Search GeneIP for patents involving PPP1R16A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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