PPP1R12C Gene
protein-coding GIFtS: 49
GCID: GC19M055602
|
|
protein phosphatase 1, regulatory subunit 12C(Previous names: leukocyte receptor cluster (LRC) member 3, protein phosphatase...)
(Previous symbol: LENG3)
| |
Aliases
for PPP1R12C gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Protein Phosphatase 1, Regulatory Subunit 12C1 2 | | Protein Phosphatase 1 Myosin-Binding Subunit Of 85 KDa2 3 | | MBS851 2 3 5 | | Protein Phosphatase 1 Myosin-Binding Subunit P852 3 | | LENG31 2 3 | | DKFZP434D04121 | | Leukocyte Receptor Cluster (LRC) Member 31 2 | | Leukocyte Receptor Cluster (LRC) Encoded Novel Gene 32 | | P841 | | Myosin-Binding Subunit 852 | | P851 | | Protein Phosphatase 1 Regulatory Subunit 12C2 | | Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 12C1 2 | | |
Export aliases for PPP1R12C gene to outside databasesPrevious GC identifers: GC19M056464 GC19M056026 GC19M060278 GC19M060294 GC19M051925 |
Summaries
for PPP1R12C gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PPP1R12C:
The gene encodes a subunit of myosin phosphatase. The encoded protein regulates the catalytic activity of proteinphosphatase 1 delta and assembly of the actin cytoskeleton. Alternatively spliced transcript variants encodingmultiple isoforms have been observed for this gene. (provided by RefSeq, Oct 2012)
UniProtKB/Swiss-Prot: PP12C_HUMAN, Q9BZL4Function: Regulates myosin phosphatase activity
|
Genomic Views
for PPP1R12C gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PPP1R12C gene promoter:
p53 Tal-1 AML1a STAT5A RelA NF-kappaB E47 NF-kappaB1 ATF ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for PPP1R12C
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PPP1R12C |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.42 Ensembl cytogenetic band: 19q13.42 HGNC cytogenetic band: 19q13.42PPP1R12C Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M055602: view genomic region
(about GC identifiers)
Start:
|
55,602,281 bp from pter |
End:
|
55,628,927 bp from pter |
Size:
|
26,647 bases |
Orientation:
|
minus strand |
|
Proteins
for PPP1R12C gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PP12C_HUMAN, Q9BZL4 (See
protein sequence)Recommended Name: Protein phosphatase 1 regulatory subunit 12C Size: 782 amino acids; 84881 Da
Subunit: PP1 comprises a catalytic subunit, PPP1CA, PPP1CB or PPP1CC, and one or several targeting or regulatorysubunits. PPP1R12C mediates binding to myosin. Interacts via its N-terminus with PPP1CB. Interacts with IL16.Interacts with the coiled-coil domain of MPRIP
Subcellular location: Cytoplasm. Note=Along actomyosin filaments and stress fibers
Caution: Although assigned as two separate genes (PPP1R12C and LENG3), it is probable that LENG3 does not exist byitself and is a part of the PPP1R12C gene
Sequence caution: Sequence=AF211968; Type=Miscellaneous discrepancy; Note=Unspliced mRNA; Sequence=BAB15651.1;Type=Erroneous initiation; Sequence=BAC85179.1; Type=Erroneous initiation;
Secondary accessions: Q59FK8 Q6ZPD1 Q7L8F7 Q96HW1 Q9H5H5 Q9NT00Alternative splicing: 4 isoforms: Q9BZL4-1 Q9BZL4-2 Q9BZL4-3 Q9BZL4-4 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for PPP1R12C: NX_Q9BZL4
Post-translational modifications:
Phosphorylation at Thr-560 is essential for its interaction with PPP1CB1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BZL4
PPP1R12C Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001258547.1 NP_060077.1
ENSEMBL proteins: ENSP00000468148 ENSP00000263433 ENSP00000467711 ENSP00000387833 ENSP00000465957 ENSP00000365573
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005737 | cytoplasm |
IEA | -- |
PPP1R12C for ontologies About GeneDecksing
PPP1R12C Antibody Products:
Assay Products for PPP1R12C: |
Protein
Domains /
Families
for PPP1R12C gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PPP1R12C for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9BZL4ProtoNet protein and cluster: Q9BZL4 UniProtKB/Swiss-Prot: PP12C_HUMAN, Q9BZL4Similarity: Contains 4 ANK repeats |
Function
for PPP1R12C gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PP12C_HUMAN, Q9BZL4Function: Regulates myosin phosphatase activity
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PPP1R12C (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PPP1R12C
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: PPP1R12C (NM_017607) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PPP1R12C | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PPP1R12C |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPP1R12C |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
IPI | -- |
PPP1R12C for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for PPP1R12C:
|
Pathways & Interactions
for PPP1R12C gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Erythropoietin Pathway | | | 2 | Activation of cAMP-Dependent PKA | | | 3 | Dopamine-DARPP32 Feedback onto cAMP Pathway | | | 4 | PEDF Induced Signaling | | | 5 | Rho Family GTPases | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/14 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for PPP1R12C (see all 14)
1  Tocris Bioscience Pathway for PPP1R12C
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PPP1R12C
STRING Interaction
Network Preview (showing 5 interactants - click image to see 16)
5/21 Interacting proteins for PPP1R12C (Q9BZL41, 2, 3 ENSP000002634334) via UniProtKB, MINT, STRING, and/or I2D (see all 21)About this table
|
Drugs & Compounds
for PPP1R12C gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for PPP1R12C
Search CenterWatch for drugs/clinical trials and news about PPP1R12C / PP12C
|
Transcripts
for PPP1R12C gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PPP1R12C gene (2 alternative transcripts): NM_001271618.1 NM_017607.3 Unigene Cluster for PPP1R12C: Protein phosphatase 1, regulatory subunit 12C Hs.631579 [show with all ESTs]Unigene Representative Sequence: AF21196810 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000591938 ENST00000263433(uc010yfs.2 uc002qix.3 uc002qiy.3)
ENST00000590268 ENST00000435544 ENST00000592993 ENST00000592754 ENST00000588277
ENST00000586197 ENST00000586992 ENST00000376393
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PPP1R12C (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PPP1R12C
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: PPP1R12C (NM_017607) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PPP1R12C | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PPP1R12C |
Additional cDNA sequence: AB209452.1 AF211968.1 AF312028.1 AK027086.1 AK129529.1 AK297187.1 AK297426.1 AL137618.1 BC008030.1 BC010628.1 9 DOTS entries: DT.216216 DT.91970981 DT.121500366 DT.91749482 DT.95236118 DT.91749478 DT.100652151 DT.99943722 DT.99969325 24/217 AceView cDNA sequences (see all 217): AA595097 BE305140 CA390602 BE293582 CA391836 AF211968 AW338489 CA390339 T33476 BE797207 BU845929 BU173579 BM756070 BI913827 AW167626 AW675175 AI095596 AA577082 CD244239 BU839107 AI161177 BU730941 BM908332 AI424915
GeneLoc Exon Structure
5/12 Alternative Splicing Database (ASD) splice patterns (SP) for PPP1R12C (see all 12) About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17a | · | 17b | ^ | 18 | ^ |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 19a | · | 19b | ^ | 20 | ^ | 21 | ^ | 22 | ^ | 23a | · | 23b | · | 23c |
|---|
|
| SP1: | - | | | | | | | | | | | | | | | | |
| SP2: | - | | | | | | | | | | | | | | | | |
| SP3: | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for PPP1R12C
|
Expression
for PPP1R12C gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PPP1R12C expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGCAATAGGG
About this image
See PPP1R12C Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PPP1R12C
SOURCE GeneReport for Unigene cluster: Hs.631579
UniProtKB/Swiss-Prot: PP12C_HUMAN, Q9BZL4Tissue specificity: Ubiquitously expressed. Highly expressed in heart
SABiosciences Custom PCR Arrays for PPP1R12C
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PPP1R12C
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PPP1R12C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PPP1R12C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PPP1R12C | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPP1R12C |
Orthologs
for PPP1R12C gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for PPP1R12C gene from 5/16 species (see all 16) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Ppp1r12c1 , 5 |
protein phosphatase 1, regulatory (inhibitor) subunit more1, 5 |
83.87(n)1
87.77(a)1 |
|
7 (2.59 cM)5
2328071 NM_029834.31 NP_084110.21
44815205 |
lizard
(Anolis carolinensis) |
Reptilia |
PPP1R12C6 |
-- |
37(a) |
1 ↔ 1 |
GL343329.1(940596-968356) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.167362 |
Xenopus laevis transcribed sequence with weak similarity more |
74.74(n) |
|
BJ029176.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
ppp1r12c1 |
protein phosphatase 1, regulatory subunit 12C |
53.77(n)
51.01(a) |
|
570218 NM_001077579.1 NP_001071047.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
Mbs6 |
Myosin binding subunit |
17(a) |
1 → many |
3L(16045059-16075126) |
ENSEMBL Gene Tree for PPP1R12C (if available)
TreeFam Gene Tree for PPP1R12C (if available) |
Paralogs
for PPP1R12C gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PPP1R12C gene
- PPP1R13B2 PPP1R16B2 PPP1R272 PPP1R12B2 TP53BP22 PPP1R12A2 NRARP2 PPP1R16A2
- PPP1R13L2
14 SIMAP similar genes for PPP1R12C using alignment to 5 protein entries: PP12C_HUMAN (see all proteins):NRARP RAI14 ANKRD12 PPP1R12A sm-M20 ASB7
PPP1R27 ANKRD46 ANKRD54 FEM1B ANKRD42 ANKRD6
PPP1R12B PSMD10
PPP1R12C for paralogs About GeneDecksing
|
Genomic Variants
for PPP1R12C gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PPP1R12C (55602281 - 55628927 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for PPP1R12C
4 CNVs: 8877 3201 10570 67616
2 Indels: 12038 26341 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PPP1R12C |
|
Disorders
/ Diseases
for PPP1R12C gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PPP1R12C for disorders About GeneDecksing
OMIM gene information: 613245
OMIM disorders: --
3  diseases for PPP1R12C: About MalaCardsmacular degeneration ataxia breast cancer
Export disorders for PPP1R12C gene to outside databases
|
Publications
for PPP1R12C gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PPP1R12C gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with PPP1R12C) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Phosphorylation of a novel myosin binding subunit of protein phosphatase 1 reveals a conserved mechanism in the regulation of actin cytoskeleton. (PubMed id 11399775)1, 2, 3 Tan I.... Leung T. (2001)
- PDZ domain-mediated interaction of interleukin-16 precursor proteins with myosin phosphatase targeting subunits. (PubMed id 12923170)1, 2 Bannert N.... Kurth R. (2003)
- Comparison of an expanded ataxia interactome with pat ient medical records reveals a relationship between macular degeneration and at axia. (PubMed id 21078624)1 Kahle J.J....Zoghbi H.Y. (2011)
- Chemical genetic screen for AMPKa2 substrates uncovers a network of proteins involved in mitosis. (PubMed id 22137581)1 Banko M.R....Brunet A. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (2008)
- ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. (PubMed id 17525332)2 Matsuoka S.... Elledge S.J. (2007)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
|
External Searches for PPP1R12C gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PPP1R12C gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing PPP1R12C gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing PPP1R12C gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for PPP1R12C | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for PPP1R12C gene:
Search GeneIP for patents involving PPP1R12C
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for PPP1R12C gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for PPP1R12C | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PPP1R12C | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PPP1R12C | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PPP1R12C | | OriGene 3'-UTR Clone for PPP1R12C | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PPP1R12C | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PPP1R12C | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PPP1R12C | | OriGene Custom Protein Services for PPP1R12C | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PPP1R12C | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PPP1R12C | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PPP1R12C | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PPP1R12C | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PPP1R12C | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PPP1R12C |
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 | | | PPP1R12C Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPP1R12C |
|  |  |  | | | | Search ThermoFisher Antibodies for PPP1R12C |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PPP1R12C |
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