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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PPP1R11 Gene

protein-coding   GIFtS: 54
GCID: GC06P030038

protein phosphatase 1, regulatory (inhibitor) subunit 11


(Previous symbol: TCTE5)
 Explore 7 diseases affiliated with
PPP1R11 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for PPP1R11    

Aliases
for PPP1R11 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 111 2     TCTEX52 5
HCGV1 2 3     Tctex51
TCTE51 2 3     IPP32
HCG-V1 2     Inhibitor-31
Hemochromatosis Candidate Gene V Protein2 3     Protein Phosphatase 1 Regulatory Subunit 112
Protein Phosphatase Inhibitor 32 3     T-Complex-Associated-Testis-Expressed 52
HCG V2 3     

External Ids:    HGNC: 92851   Entrez Gene: 69922   Ensembl: ENSG000002046197   OMIM: 6066705   UniProtKB: O609273   

Export aliases for PPP1R11 gene to outside databases

Previous GC identifers: GC06P030090 GC06P029805 GC06P030141 GC06P030142 GC06P030037


Summaries
for PPP1R11 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for PPP1R11:
This gene encodes a specific inhibitor of protein phosphatase-1 (PP1) with a differential sensitivity toward the
metal-independent and metal-dependent forms of PP1. The gene is located within the major histocompatibility complex
class I region on chromosome 6. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: PP1RB_HUMAN, O60927
Function: Inhibitor of protein phosphatase 1

Gene Wiki entry for PPP1R11


Genomic Views
for PPP1R11 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  NT_113891.2  NT_167244.1  NT_167245.1  NT_167246.1  NT_167247.1  
NT_167248.1  NT_167249.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PPP1R11 gene promoter:
         AML1a   RREB-1   Bach2   FOXO3   AP-4   Nkx2-5   Arnt   FOXO3b   FOXO3a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: PPP1R11 promoter sequence
   Search SABiosciences Chromatin IP Primers for PPP1R11

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PPP1R11


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p22.1   HGNC cytogenetic band: 6p21.3

PPP1R11 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PPP1R11 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P030038:  view genomic region     (about GC identifiers)

Start:
 30,034,486 bp from pter      End:
 30,038,110 bp from pter
Size:
 3,625 bases      Orientation:
 plus strand

6/7 alternative locations (see all 7):
Chr6+,ALT_REF_LOCI_2 30,024,382-30,067,194      Chr6+,ALT_REF_LOCI_6 30,024,068-30,063,273      Chr6+,ALT_REF_LOCI_5 30,028,253-30,031,431     
Chr6+,ALT_REF_LOCI_3 30,024,813-30,039,475      Chr6+,ALT_REF_LOCI_1 29,971,320-29,983,244      Chr6+,ALT_REF_LOCI_4 29,953,183-29,956,362     

Proteins
for PPP1R11 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: PP1RB_HUMAN, O60927 (See protein sequence)
Recommended Name: Protein phosphatase 1 regulatory subunit 11  
Size: 126 amino acids; 13953 Da

Explore the universe of human proteins at neXtProt for PPP1R11: NX_O60927

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O60927

    • PPP1R11 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_068778.1  
    ENSEMBL proteins: 
     ENSP00000365964   ENSP00000365963   ENSP00000365960   ENSP00000365956   ENSP00000365954  
     ENSP00000365949  

    Human Recombinant Protein Products: 
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    OriGene Purified Protein: PPP1R11
    OriGene Protein Over-expression Lysate: PPP1R11
    OriGene Custom Protein Services for PPP1R11 
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    Novus Biologicals PPP1R11 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for PPP1R11

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005625soluble fraction ----
    GO:0005737cytoplasm ISS--


    PPP1R11 for ontologies           About GeneDecksing



    PPP1R11 Antibody Products: 
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    Uscn Antibodies for PPP1R11
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    Assay Products for PPP1R11: 
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    Uscn ELISAs and CLIAs for PPP1R11

    Protein Domains /
    Families
    for PPP1R11 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    PPP1R11 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR011107 PPI_Ypi1

    Graphical View of Domain Structure for InterPro Entry O60927

    ProtoNet protein and cluster: O60927

    1 Blocks protein family: IPB011107 Protein phosphatase inhibitor


    Function
    for PPP1R11 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: PP1RB_HUMAN, O60927
    Function: Inhibitor of protein phosphatase 1

         Genatlas biochemistry entry for PPP1R11:
    protein phosphatase 1,regulatory (inhibitor) subunit 11,t-complex associated, expressed in testis,mouse Tctex 5
    homolog,with a calculator mass of 14kDa and an apparent mass of 23kDa

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PPP1R11
    8/31 QIAGEN miScript miRNA Assays for microRNAs that regulate PPP1R11 (see all 31):
    hsa-miR-320a hsa-miR-146a hsa-miR-15a hsa-miR-1271 hsa-miR-503 hsa-miR-449a hsa-miR-3159 hsa-miR-877*
    SwitchGear 3'UTR luciferase reporter plasmid: PPP1R11 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PPP1R11 (see all 7)
    OriGene shRNA RFP: PPP1R11
    OriGene siRNA: PPP1R11
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PPP1R11

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for PPP1R11

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PPP1R11 (see all 3)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PPP1R11 

    Cell Line
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    Search LifeMap BioReagents cell lines for PPP1R11

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPP1R11

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004864protein phosphatase inhibitor activity IEA--


    PPP1R11 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for PPP1R11:
     Increased apoptosis 


    Pathways & Interactions
    for PPP1R11 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Erythropoietin Pathway
    		Erythropoietin Pathway1.00
    		Insulin Receptor Pathway0.37
    		Beta-Adrenergic Signaling0.37
    		CDK5 Pathway0.21
    2Activation of cAMP-Dependent PKA
    		Activation of cAMP-Dependent PKA1.00
    		Activation of PKA through GPCR0.71
    		cAMP Pathway0.77
    		PKA Signaling0.56
    3Dopamine-DARPP32 Feedback onto cAMP Pathway
    		Dopamine-DARPP32 Feedback onto cAMP Pathway1.00
    4PEDF Induced Signaling
    		IL-6 Pathway0.61
    5Rho Family GTPases
    		ERK Signaling0.61

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    5/14 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for PPP1R11 (see all 14)
        Activation of PKA through GPCR
    PKA Signaling
    eIF2 Pathway
    CDK5 Pathway
    Breast Cancer Regulation by Stathmin1

    1 Tocris Bioscience Pathway for PPP1R11
        Insulin Pathway


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PPP1R11

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    3 Interacting proteins for PPP1R11 (O609272, 3 ENSP000003659634) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PPP1CAP621363, ENSP000003260314I2D: score=1 STRING: ENSP00000326031
    PPP1CBP621403I2D: score=2 
    --P621392MINT-8216263 MINT-8216253
    About this table

    Drugs & Compounds
    for PPP1R11 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    EMD Millipore small molecules for PPP1R11:
    Small Molecule - inhibitor
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PPP1R11
    Search CenterWatch for drugs/clinical trials and news about PPP1R11 / PP1RB 

    Transcripts
    for PPP1R11 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for PPP1R11 gene (2 alternative transcripts): 
    NM_021959.2  NM_170781.1  

    Unigene Cluster for PPP1R11:

    Protein phosphatase 1, regulatory (inhibitor) subunit 11
    Hs.82887  [show with all ESTs]
    Unigene Representative Sequence: NM_021959
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000376773 ENST00000376772(uc003npb.3) ENST00000376769(uc010jrw.3 uc003npc.3)
    ENST00000376765 ENST00000376763 ENST00000376758

    miRNA
    Products:             		 OriGene 3'-UTR Clone: PPP1R11
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PPP1R11
    8/31 QIAGEN miScript miRNA Assays for microRNAs that regulate PPP1R11 (see all 31):
    hsa-miR-320a hsa-miR-146a hsa-miR-15a hsa-miR-1271 hsa-miR-503 hsa-miR-449a hsa-miR-3159 hsa-miR-877*
    SwitchGear 3'UTR luciferase reporter plasmid: PPP1R11 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PPP1R11 (see all 7)
    OriGene shRNA RFP: PPP1R11
    OriGene siRNA: PPP1R11
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PPP1R11
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PPP1R11
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: PPP1R11 (NM_021959)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for PPP1R11
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PPP1R11 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PPP1R11
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PPP1R11
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PPP1R11

    Additional cDNA sequence: 

    AK313175.1 BC102010.1 BC102011.1 BC104750.1 L19688.1 X81003.1 

    23 DOTS entries:

    DT.100879019  DT.100758574  DT.100879013  DT.100809343  DT.446865  DT.121346035  DT.100879008  DT.121345708 
    DT.121346122  DT.421508  DT.121346196  DT.100879012  DT.121346402  DT.91766671  DT.100879015  DT.121346395 
    DT.91766674  DT.100805838  DT.100879022  DT.95238264  DT.121345925  DT.40282144  DT.95165665 

    6 AceView cDNA sequences:

    X81003 NM_021959 CR625861 NM_170781 BC003144 AF070599 

    GeneLoc Exon Structure


    Expression
    for PPP1R11 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PPP1R11 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGTAGCGAAC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    PPP1R11 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    OvaryAntral FollicleSecondary OocyteFemale Gametocytes, Germ Cells
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See PPP1R11 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PPP1R11

    SOURCE GeneReport for Unigene cluster: Hs.82887

    UniProtKB/Swiss-Prot: PP1RB_HUMAN, O60927
    Tissue specificity: Widely expressed

        SABiosciences Custom PCR Arrays for PPP1R11
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPP1R11

    Orthologs
    for PPP1R11 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of eukaryotes.

    Orthologs for PPP1R11 gene from 8/23 species (see all 23)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Ppp1r111 , 5 protein phosphatase 1, regulatory (inhibitor) subunit more1, 5 86.51(n)1
    88.89(a)1    		   17 (19.16 cM)5
    764971  NM_029632.31  NP_083908.11 
     369483565 
    lizard
    (Anolis carolinensis)    		 Reptilia PPP1R116
    		 --
    		 56(a)
    		 1 ↔ 1
    		 2(192714230-192719388)
    African clawed frog
    (Xenopus laevis)    		 Amphibia BJ034908.12   -- 73.17(n)    BJ034908.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii wufj64e042 Transcribed sequence with weak similarity to protein more 75.73(n)    CD594591.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG139946
    I-36
    		 Inhibitor-3
    		 25(a)
    18(a)
    		 many → 1
    many → 1
    		 2L(6063018-6063676)
    X(20752841-20753653)
    worm
    (Caenorhabditis elegans)    		 Secernentea C07H6.26
    ZK945.86
    (see all 3)    		 Uncharacterized protein ZK945.8
    (see all 3)    		 34(a)
    28(a)
    (see all 3)    		 many → 1
    many → 1
    (see all 3)    		 III(7520938-7521398)
    II(10108635-10109143)
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons INH36
    		 inhibitor-3
    		 24(a)
    		 1 ↔ 1
    		 2(13350422-13351464)
    rice
    (Oryza sativa)    		 Liliopsida --
    --
    		 protein phosphatase 1 regulatory subunit 11, putat...
    protein phosphatase 1 regulatory subunit 11, putat...
    		 25(a)
    23(a)
    		 many → 1
    many → 1
    		 4(12944210-12945436)
    5(10899622-10900864)


    ENSEMBL Gene Tree for PPP1R11 (if available)
    TreeFam Gene Tree for PPP1R11 (if available) 

    Paralogs
    for PPP1R11 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PPP1R11 gene

    PPP1R11 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for PPP1R11
    PGOHUM00000244630 PGOHUM00000241800


    Genomic Variants
    for PPP1R11 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/103 NCBI SNPs in PPP1R11 are shown (see all 103)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1468735431,2
    		--30033056(+) TGAACA/CACACA 3 -- ds5001 us2k10--------
    rs1407327201,2
    		--30033112(+) TCTGAC/GACCCA 3 -- ds5001 us2k10--------
    rs734223201,2
    		C,--30033282(+) GTATTA/GTAAGT 1 -- us2k12Minor allele frequency- G:0.09WA 120
    rs2002934421,2
    		--30033353(+) TCAAC-/AGTAGTAA 1 -- us2k10--------
    rs92808811,2
    		C,--30033357(+) CAGTA-/GTTAAGTT 1 -- us2k10--------
    rs1150564851,2
    		F,--30033448(+) AATTGT/CATATC 1 -- us2k11Minor allele frequency- C:0.03NA 120
    rs31215951,2
    		C,A,H,--30033472(-) TCTATA/GTAAGA 1 -- us2k19Minor allele frequency- G:0.09NA WA CSA EA 369
    rs1909557861,2
    		--30033484(+) AGAAAG/TAAAAA 1 -- us2k10--------
    rs1826102831,2
    		--30033505(+) CAAGGA/GATCCT 1 -- us2k10--------
    rs1431609421,2
    		--30033572(+) GCTCTA/GTATAT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for PPP1R11 (30034486 - 30038110 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for PPP1R11: --

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    Disorders / Diseases
    for PPP1R11 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    PPP1R11 for disorders           About GeneDecksing

    OMIM gene information: 606670    OMIM disorders: --

    7 diseases for PPP1R11:    About MalaCards
    hemochromatosis    systemic lupus erythematosus    lupus erythematosus    intrahepatic cholangiocarcinoma
    cholangiocarcinoma    malaria    breast cancer

    Human Genome Epidemiology (HuGE) Navigator: PPP1R11 (2 documents)

    Export disorders for PPP1R11 gene to outside databases

    Publications
    for PPP1R11 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PPP1R11 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with PPP1R11)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of the human HCG V gene product as a novel inhibitor of protein phosphatase-1. (PubMed id 9843442)1, 2, 3, 9 Zhang J.... Lee E.Y.C. (1998)
    2. Cloning of a human homologue of the mouse Tctex-5 gene within the MHC class I region. (PubMed id 8781118)1, 2, 3 Giffon T....David V. (1996)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    5. Systematic sequencing of the human HLA-A/HLA-F region: establishment of a cosmid contig and identification of a new gene cluster within 37 kb of sequence. (PubMed id 8938444)1, 2 Lepourcelet M.... Mosser J. (1996)
    6. Genome-wide association study identifies multiple loci influencing human serum metabolite levels. (PubMed id 22286219)1 Kettunen J....Ripatti S. (2012)
    7. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
    8. Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
    9. High-density SNP screening of the major histocompatib ility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1 Barcellos L.F....Criswell L.A. (2009)
    10. Identification of the interaction sites of Inhibitor-3 for protein phosphatase-1. (PubMed id 18951879)1 Zhang L....Lee E.Y. (2008)

    External Searches for PPP1R11 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing PPP1R11 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 6992 HGNC: 9285 AceView: PPP1R11 Ensembl:ENSG00000204619 euGenes: HUgn6992
    ECgene: PPP1R11 H-InvDB: PPP1R11

    Other Databases showing PPP1R11 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing PPP1R11 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PPP1R11 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for PPP1R11 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for PPP1R11 gene:
    Search GeneIP for patents involving PPP1R11

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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