Aliases for PPP1R10 Gene
- Protein Phosphatase 1 Regulatory Subunit 10 2 3 5
- Phosphatase 1 Nuclear Targeting Subunit 2 3 4
- Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 10 2 3
- MHC Class I Region Proline-Rich Protein CAT53 3 4
- Protein Phosphatase 1, Regulatory Subunit 10 2 3
- HLA-C Associated Transcript 53 2 3
- PP1-Binding Protein Of 114 KDa 3 4
- CAT53 3 4
External Ids for PPP1R10 Gene
Previous GeneCards Identifiers for PPP1R10 Gene
This gene encodes a protein phosphatase 1 binding protein. The encoded protein plays a role in many cellular processes including cell cycle progression, DNA repair and apoptosis by regulating the activity of protein phosphatase 1. This gene lies within the major histocompatibility complex class I region on chromosome 6, and alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
GeneCards Summary for PPP1R10 Gene
PPP1R10 (Protein Phosphatase 1 Regulatory Subunit 10) is a Protein Coding gene. Among its related pathways are Activation of cAMP-Dependent PKA and Beta-Adrenergic Signaling. GO annotations related to this gene include poly(A) RNA binding and protein phosphatase inhibitor activity. An important paralog of this gene is PRR3.
UniProtKB/Swiss-Prot for PPP1R10 Gene
Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers (By similarity).