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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PPIL4 Gene

protein-coding   GIFtS: 55
GCID: GC06M149867

Peptidylprolyl Isomerase (Cyclophilin)-Like 4

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Peptidylprolyl Isomerase (Cyclophilin)-Like 41 2     HDCME13P2
Cyclophilin-Like Protein PPIL42 3     Cyclophilin-Type Peptidyl-Prolyl Cis-Trans Isomerase2
Rotamase PPIL42 3     Peptidyl-Prolyl Cis-Trans Isomerase-Like 42
PPIase2 3     Serologically Defined Breast Cancer Antigen NY-BR-182
EC 5.2.1.83 8     

External Ids:    HGNC: 157021   Entrez Gene: 853132   Ensembl: ENSG000001310137   OMIM: 6076095   UniProtKB: Q8WUA23   

Export aliases for PPIL4 gene to outside databases

Previous GC identifers: GC06M149338 GC06M149672 GC06M149760 GC06M149806 GC06M147392


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for PPIL4 Gene:
This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly
conserved family, members of which play an important role in protein folding, immunosuppression by cyclosporin A,
and infection of HIV-1 virions. (provided by RefSeq, Jul 2008)

GeneCards Summary for PPIL4 Gene: 
PPIL4 (peptidylprolyl isomerase (cyclophilin)-like 4) is a protein-coding gene. Diseases associated with PPIL4 include gout, and breast cancer. GO annotations related to this gene include peptidyl-prolyl cis-trans isomerase activity and RNA binding. An important paralog of this gene is PPIH.

UniProtKB/Swiss-Prot: PPIL4_HUMAN, Q8WUA2
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic
peptide bonds in oligopeptides (By similarity)

Gene Wiki entry for PPIL4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_025741.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PPIL4 gene promoter:
         Elk-1   Pbx1a   NRSF form 2   HNF-3beta   CREB   PPAR-gamma1   FAC1   deltaCREB   PPAR-gamma2   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidPPIL4 promoter sequence
   Search SABiosciences Chromatin IP Primers for PPIL4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PPIL4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q25.1   Ensembl cytogenetic band:  6q25.1   HGNC cytogenetic band: 6q25.1

PPIL4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PPIL4 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M149867:  view genomic region     (about GC identifiers)

Start:
149,825,631 bp from pter      End:
149,867,238 bp from pter
Size:
41,608 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: PPIL4_HUMAN, Q8WUA2 (See protein sequence)
Recommended Name: Peptidyl-prolyl cis-trans isomerase-like 4  
Size: 492 amino acids; 57225 Da
Subcellular location: Nucleus (Probable)
Secondary accessions: B2RD34 Q7Z3Q5

Explore the universe of human proteins at neXtProt for PPIL4: NX_Q8WUA2

Explore proteomics data for PPIL4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8WUA2

  • 4/7 DME Specific Peptides for PPIL4 (Q8WUA2) (see all 7)
     GDPTGTG  QTGDPTG  SCEVIRD  VDFSQSV 

    PPIL4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    PPIL4 Protein Expression
    REFSEQ proteins: NP_624311.1  
    ENSEMBL proteins: 
     ENSP00000253329   ENSP00000344128  

    Human Recombinant Protein Products for PPIL4: 
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    Novus Biologicals PPIL4 Proteins
    Novus Biologicals PPIL4 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    ProSpec Recombinant Protein for PPIL4
    Cloud-Clone Corp. Proteins for PPIL4 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    PPIL4 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    RBM: RNA binding motif (RRM) containing

    3 InterPro protein domains:
     IPR002130 Cyclophilin-like_PPIase_dom
     IPR012677 Nucleotide-bd_a/b_plait
     IPR000504 RRM_dom

    Graphical View of Domain Structure for InterPro Entry Q8WUA2

    ProtoNet protein and cluster: Q8WUA2

    2 Blocks protein domains:
    IPB000504 RNA-binding region RNP-1 (RNA recognition motif)
    IPB002130 Peptidyl-prolyl cis-trans isomerase


    UniProtKB/Swiss-Prot: PPIL4_HUMAN, Q8WUA2
    Similarity: Belongs to the cyclophilin-type PPIase family. PPIL4 subfamily
    Similarity: Contains 1 PPIase cyclophilin-type domain
    Similarity: Contains 1 RRM (RNA recognition motif) domain


    PPIL4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PPIL4_HUMAN, Q8WUA2
    Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic
    peptide bonds in oligopeptides (By similarity)
    Catalytic activity: Peptidylproline (omega=180) = peptidylproline (omega=0)

         Enzyme Number (IUBMB): EC 5.2.1.81 2

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding IEA--
    GO:0003676nucleic acid binding ----
    GO:0003723RNA binding IEA--
    GO:0003755peptidyl-prolyl cis-trans isomerase activity IEA--
         
    PPIL4 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for PPIL4:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for PPIL4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for PPIL4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for PPIL4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for PPIL4 

    miRNA
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    8/26 QIAGEN miScript miRNA Assays for microRNAs that regulate PPIL4 (see all 26):
    hsa-miR-30c hsa-miR-300 hsa-miR-520d-5p hsa-miR-15a hsa-miR-30d hsa-miR-410 hsa-miR-548l hsa-miR-424
    SwitchGear 3'UTR luciferase reporter plasmidPPIL4 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Clone
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPIL4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PPIL4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/12 Interacting proteins for PPIL4 (Q8WUA22, 3 ENSP000002533294) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SMAD5Q997172, 3MINT-61839 I2D: score=3 
    CHERPQ8IWX82, ENSP000001989394MINT-8334714 STRING: ENSP00000198939
    USP7Q930093, ENSP000003435354I2D: score=2 STRING: ENSP00000343535
    SNW1ENSP000002615314STRING: ENSP00000261531
    SUMO2ENSP000004059654STRING: ENSP00000405965
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006457protein folding IEA--

    PPIL4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PPIL4

    Search CenterWatch for drugs/clinical trials and news about PPIL4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for PPIL4 gene: 
    NM_139126.3  

    Unigene Cluster for PPIL4:

    Peptidylprolyl isomerase (cyclophilin)-like 4
    Hs.744238  [show with all ESTs]
    Unigene Representative Sequence: NM_139126
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000253329(uc003qmo.2 uc003qmp.2) ENST00000340881
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PPIL4
    8/26 QIAGEN miScript miRNA Assays for microRNAs that regulate PPIL4 (see all 26):
    hsa-miR-30c hsa-miR-300 hsa-miR-520d-5p hsa-miR-15a hsa-miR-30d hsa-miR-410 hsa-miR-548l hsa-miR-424
    SwitchGear 3'UTR luciferase reporter plasmidPPIL4 3' UTR sequence
    Inhib. RNA
    Products:
         
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    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PPIL4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PPIL4

    Additional mRNA sequence: 

    AF068298.1 AF308286.1 AF357880.1 AK315388.1 BC016984.1 BC020986.1 BC064134.1 BC107684.1 
    BX537536.1 

    9 DOTS entries:

    DT.211717  DT.91920068  DT.100763576  DT.100817609  DT.100817610  DT.121396432  DT.91651145  DT.91943554 
    DT.95164049 

    24/154 AceView cDNA sequences (see all 154):

    BC064134 AA132362 AA425562 AA053882 BX504568 AI400941 BQ019220 BM759666 
    CB160587 BE670173 AA132257 AA346646 CA441139 BU076634 AK092069 NM_139126 
    BQ007972 BM757769 CA418740 AI880208 BC016984 BM562747 BE887609 AF357880 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PPIL4 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCAATCAAAA
    PPIL4 Expression
    About this image


    See PPIL4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PPIL4

    SOURCE GeneReport for Unigene cluster: Hs.744238

    UniProtKB/Swiss-Prot: PPIL4_HUMAN, Q8WUA2
    Tissue specificity: Abundantly expressed in kidney but has a ubiquitously low expression pattern in other adult
    tissues

        SABiosciences Custom PCR Arrays for PPIL4
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPIL4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for PPIL4 gene from 10/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ppil41 , 5 peptidylprolyl isomerase (cyclophilin)-like 41, 5 91.06(n)1
    96.75(a)1
      10 (2.38 cM)5
    674181  NM_026141.31  NP_080417.21 
     77928915 
    chicken
    (Gallus gallus)
    Aves PPIL41 peptidylprolyl isomerase (cyclophilin)-like 4 78.17(n)
    83.47(a)
      421625  XM_419663.3  XP_419663.2 
    lizard
    (Anolis carolinensis)
    Reptilia PPIL46
    Uncharacterized protein
    79(a)
    1 ↔ 1
    GL343259.1(191016-216268)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.59042 Transcribed sequence with weak similarity to protein more 79.3(n)    BX736441.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi40d032 wufi40d03 77.74(n)   334319  BC056814.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta BcDNA:GH010733
    CG58081
    RNA binding3
    CG58081
    54(a)3
    54.89(n)1
    51.45(a)1
      96A233
    429571  NM_143034.41  NP_651291.11 
    worm
    (Caenorhabditis elegans)
    Secernentea sig-71 Protein SIG-7 55.56(n)
    52.88(a)
      172664  NM_059942.4  NP_492343.2 
    A. gossypii yeast
    (Ashbya gossypii)
    Saccharomycetes AGOS_AFR649W1 AFR649Wp 45.08(n)
    38.26(a)
      4622485  NM_212333.1  NP_986197.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons CYP591 cyclophilin 59 55.44(n)
    49.05(a)
      841810  NM_104250.4  NP_175776.2 
    rice
    (Oryza sativa)
    Liliopsida Os.210142 Oryza sativa (japonica cultivar-group) cDNA cloneJ more 74.9(n)    AK099323.1 


    ENSEMBL Gene Tree for PPIL4 (if available)
    TreeFam Gene Tree for PPIL4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PPIL4 gene
    PPIH2  PPIC2  PPIB2  CWC272  PPWD12  PPIL22  PPIL32  PPIL12  
    9 SIMAP similar genes for PPIL4 using alignment to 4 protein entries:     PPIL4_HUMAN (see all proteins):
    PPIL3    PPIL1    PPIF    PPIA    PPIAL4D    PPIB
    PPIH    SRSF5    NKTR

    PPIL4 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for PPIL4
    PGOHUM00000233120


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/807 SNPs in PPIL4 are shown (see all 807)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1408443271,2
    C--149825212(+) AAAAAC/TAGAGG 1 -- ds50010--------
    rs48957921,2
    C,F,A,H--149825264(+) CCAGAA/C/TAGAAA 1 -- ds500125NS EA NA WA CSA 2247
    rs1459253961,2
    --149825304(+) AAAAAC/TACCTG 1 -- ds50010--------
    rs782413181,2
    --149825402(+) ACAGAC/GAGAAA 1 -- ds50010--------
    rs1909118541,2
    --149825539(+) GAAAAA/CATGCC 1 -- ds50010--------
    rs1834195891,2
    --149825584(+) CACAGA/GTAAAA 1 -- ds50010--------
    rs48957931,2
    C,H--149825609(+) GAAACG/ATGAAA 1 -- ds50014Minor allele frequency- A:0.00NS EA 418
    rs1867215961,2
    --149825845(+) CCAAGA/GGAGGT 1 -- ut310--------
    rs1158782641,2
    C--149825977(+) AAAACG/TCAAAT 1 -- ut310--------
    rs1379533201,2
    C--149826110(+) ACATTA/TCACTT 1 -- ut310--------

    HapMap Linkage Disequilibrium report for PPIL4 (149825631 - 149867238 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for PPIL4:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv886762CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing PPIL4
    DNA2.0 Custom Variant and Variant Library Synthesis for PPIL4

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607609    OMIM disorders: --

    4 diseases for PPIL4:    About MalaCards
    gout    breast cancer    pneumonia    colon cancer


    PPIL4 for disorders           About GeneDecksing


    Export disorders for PPIL4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for PPIL4 gene, integrated from 9 sources (see all 23):
    (articles sorted by number of sources associating them with PPIL4)
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    1. Molecular cloning, structure and expression of a novel nuclear RNA- binding cyclophilin-like gene (PPIL4) from human fetal brain. (PubMed id 11978968)1, 2, 9 Zeng L.... Mao Y. (2001)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    6. Quantitative study of the interactome of PKCz involved in the EGF-induced tumor cell chemotaxis. (PubMed id 23402259)1 Chen R....Zhang N. (2013)
    7. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
    8. Dynamic protein-protein interaction wiring of the huma n spliceosome. (PubMed id 22365833)1 Hegele A....Stelzl U. (2012)
    9. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 85313 HGNC: 15702 AceView: FLJ46041 Ensembl:ENSG00000131013 euGenes: HUgn85313
    ECgene: PPIL4 H-InvDB: PPIL4

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PPIL4 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for PPIL4 gene:
    Search GeneIP for patents involving PPIL4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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