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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

PPIL3 Gene

protein-coding   GIFtS: 50
GCID: GC02M201737

peptidylprolyl isomerase (cyclophilin)-like 3
 Explore 3 diseases affiliated with
PPIL3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for PPIL3    

Aliases
for PPIL3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Peptidylprolyl Isomerase (Cyclophilin)-Like 31 2     EC 5.2.1.83 8
CyPJ1 3     CYPJ2
Cyclophilin J2 3     Cyclophilin-Like Protein 32
Cyclophilin-Like Protein PPIL32 3     Peptidyl-Prolyl Cis-Trans Isomerase-Like 32
Rotamase PPIL32 3     Peptidylprolyl Cis-Trans Isomerase-Like Protein 32
PPIase2 3     PPIase-Like Protein 32

External Ids:    HGNC: 92621   Entrez Gene: 539382   Ensembl: ENSG000002403447   UniProtKB: Q9H2H83   

Export aliases for PPIL3 gene to outside databases

Previous GC identifers: GC02M199952 GC02M200460 GC02M201699 GC02M201938 GC02M201561 GC02M201443 GC02M201736 GC02M201718 GC02M193587


Summaries
for PPIL3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for PPIL3:
This gene encodes a member of the cyclophilin family. Cyclophilins catalyze the cis-trans isomerization of
peptidylprolyl imide bonds in oligopeptides. They have been proposed to act either as catalysts or as molecular
chaperones in protein-folding events. Alternative splicing results in multiple transcript variants. (provided by
RefSeq, Sep 2008)

UniProtKB/Swiss-Prot: PPIL3_HUMAN, Q9H2H8
Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic
peptide bonds in oligopeptides. May be involved in pre-mRNA splicing

Gene Wiki entry for PPIL3


Genomic Views
for PPIL3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_005403.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the PPIL3 gene promoter:
         PPAR-gamma1   SRY   CBF-A   CBF-B   FOXO4   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: PPIL3 promoter sequence
   Search SABiosciences Chromatin IP Primers for PPIL3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PPIL3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q33.1   Ensembl cytogenetic band:  2q33.1   HGNC cytogenetic band: 2q33.1

PPIL3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
PPIL3 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M201737:  view genomic region     (about GC identifiers)

Start:
 201,735,630 bp from pter      End:
 201,754,026 bp from pter
Size:
 18,397 bases      Orientation:
 minus strand

Proteins
for PPIL3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: PPIL3_HUMAN, Q9H2H8 (See protein sequence)
Recommended Name: Peptidyl-prolyl cis-trans isomerase-like 3  
Size: 161 amino acids; 18155 Da
Subunit: Identified in the spliceosome C complex
3 PDB 3D structures from and Proteopedia for PPIL3:
1XYH (3D)        2OJU (3D)        2OK3 (3D)    
Secondary accessions: Q86WF9 Q96IA9 Q9BXZ1
Alternative splicing: 2 isoforms:  Q9H2H8-1   Q9H2H8-2   

Explore the universe of human proteins at neXtProt for PPIL3: NX_Q9H2H8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9H2H8

    • 4/11 DME Specific Peptides for PPIL3 (Q9H2H8) (see all 11)
     PKTCENF  ENFLALC  GDPTGTG  QTGDPTG 

    PPIL3 Protein expression data from MOPED and PaxDb:    About this image 
    PPIL3 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_115861.1  NP_570981.1  

    ENSEMBL proteins: 
     ENSP00000286175   ENSP00000376107   ENSP00000400726   ENSP00000386893   ENSP00000386235  
     ENSP00000387012   ENSP00000391082   ENSP00000401196  

    Human Recombinant Protein Products for PPIL3: 
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    OriGene Purified Proteins (see all 2): PPIL3
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    Novus Biologicals PPIL3 Proteins
    Novus Biologicals PPIL3 Lysates
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for PPIL3
    Uscn Proteins for PPIL3

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0071013catalytic step 2 spliceosome IDA11991638

    PPIL3 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for PPIL3

    Protein Domains /
    Families
    for PPIL3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    PPIL3 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR002130 Cyclophilin-like_PPIase_dom
     IPR024936 Cyclophilin-type_PPIase
     IPR020892 Cyclophilin-type_PPIase_CS

    Graphical View of Domain Structure for InterPro Entry Q9H2H8

    ProtoNet protein and cluster: Q9H2H8

    1 Blocks protein family: IPB002130 Peptidyl-prolyl cis-trans isomerase

    UniProtKB/Swiss-Prot: PPIL3_HUMAN, Q9H2H8
    Similarity: Belongs to the cyclophilin-type PPIase family. PPIL3 subfamily
    Similarity: Contains 1 PPIase cyclophilin-type domain


    Function
    for PPIL3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PPIL3_HUMAN, Q9H2H8
    Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic
    peptide bonds in oligopeptides. May be involved in pre-mRNA splicing
    Catalytic activity: Peptidylproline (omega=180) = peptidylproline (omega=0)

         Enzyme Number (IUBMB): EC 5.2.1.81 2

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003755peptidyl-prolyl cis-trans isomerase activity IEA--
    GO:0005515protein binding IPI18474220
         
    PPIL3 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for PPIL3 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PPIL3
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate PPIL3:
    hsa-miR-30c hsa-miR-30a hsa-miR-30b hsa-miR-30d hsa-miR-1322 hsa-miR-216b hsa-miR-497* hsa-miR-30e
    SwitchGear 3'UTR luciferase reporter plasmid: PPIL3 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PPIL3 (see all 7)
    OriGene shRNA RFP: PPIL3
    OriGene siRNA: PPIL3
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    Sirion Biotech Custom design and validation of potent shRNA sequences against PPIL3 

    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of PPIL3 
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    Clone
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    Cell Line
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    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPIL3


    Pathways & Interactions
    for PPIL3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for PPIL3

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/6 Interacting proteins for PPIL3 (Q9H2H81, 2, 3 ENSP000002861754) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SLU7O953912, 3, ENSP000002971514MINT-8337717 I2D: score=4 STRING: ENSP00000297151
    PCBP1Q153652, ENSP000003055564MINT-8337728 STRING: ENSP00000305556
    KBTBD7Q8WVZ93I2D: score=1 
    UBCENSP000003448184STRING: ENSP00000344818
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000398mRNA splicing, via spliceosome IC11991638
    GO:0006457protein folding IEA--

    PPIL3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for PPIL3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for PPIL3
    Search CenterWatch for drugs/clinical trials and news about PPIL3 

    Transcripts
    for PPIL3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for PPIL3 gene (3 alternative transcripts): 
    NM_032472.3  NM_130906.2  NM_131916.1  

    Unigene Cluster for PPIL3:

    Peptidylprolyl isomerase (cyclophilin)-like 3
    Hs.121076  [show with all ESTs]
    Unigene Representative Sequence: BC007693
    15 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000286175(uc002uwi.3) ENST00000392283(uc021vut.1 uc002uwh.3)
    ENST00000465823(uc002uwj.3) ENST00000415562 ENST00000409264 ENST00000409361
    ENST00000409449 ENST00000463866 ENST00000497263 ENST00000443398 ENST00000457063
    ENST00000492074 ENST00000470442 ENST00000497501 ENST00000487879

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PPIL3
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate PPIL3:
    hsa-miR-30c hsa-miR-30a hsa-miR-30b hsa-miR-30d hsa-miR-1322 hsa-miR-216b hsa-miR-497* hsa-miR-30e
    SwitchGear 3'UTR luciferase reporter plasmid: PPIL3 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PPIL3 (see all 7)
    OriGene shRNA RFP: PPIL3
    OriGene siRNA: PPIL3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PPIL3
    Sirion Biotech Custom design and validation of potent shRNA sequences against PPIL3 
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PPIL3 (see all 3)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): PPIL3 (NM_130906)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PPIL3 
    Primer
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    Additional cDNA sequence: 

    AF146799.1 AF251049.1 AF271652.1 AF414127.1 AK297804.1 AY257468.1 BC007693.2 BC031679.1 

    12 DOTS entries:

    DT.120963407  DT.453346  DT.97811336  DT.97842807  DT.91745617  DT.120963372  DT.100783837  DT.95374017 
    DT.97842811  DT.120963376  DT.120963378  DT.40308762 

    24/66 AceView cDNA sequences (see all 66):

    AA831229 AA708524 AF251049 BM353868 BQ576291 NM_130906 CB121730 BU195819 
    NM_131916 AF414127 BF222250 CA397715 AY257468 CB049984 BQ575690 BG656363 
    AF271652 NM_032472 BG755237 BG027537 BX096814 AL046063 BM753175 BG656059 

    GeneLoc Exon Structure


    Expression
    for PPIL3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    PPIL3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCAACCCATT
    PPIL3 Expression
    About this image

    PPIL3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table

    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    OvaryPrimary FolliclePrimary OocyteFemale Gametocytes, Germ Cells
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See PPIL3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for PPIL3

    SOURCE GeneReport for Unigene cluster: Hs.121076

    UniProtKB/Swiss-Prot: PPIL3_HUMAN, Q9H2H8
    Tissue specificity: Ubiquitous. Detected at low levels

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    In Situ
    Assay Products:     
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    Orthologs
    for PPIL3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the last universal common ancestor (LUCA).

    Orthologs for PPIL3 gene from 9/34 species (see all 34)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves PPIL31 peptidylprolyl isomerase (cyclophilin)-like 3 81.46(n)
    95(a)    		   424075  NM_001008475.1  NP_001008475.1 
    lizard
    (Anolis carolinensis)    		 Reptilia PPIL36
    		 --
    		 76(a)
    		 1 ↔ 1
    		 1(118123060-118130617)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.171542 Transcribed sequence with weak similarity to protein more 75.2(n)    137709402 
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.169902 Transcribed sequence with weak similarity to protein more 77.3(n)    CB355771.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG117771 , 3 cyclophilin-type peptidy-prolyl cis-trans
    isomerase3
    CG117771    		 53(a)3
    67.08(n)1
    71.87(a)1    		   47A93
    361081  NM_165776.31  NP_724939.11 
    worm
    (Caenorhabditis elegans)    		 Secernentea cyp-103
    cyn-101    		 Cyclophilin3
    Protein CYN-101    		 49(a)3
    65.62(n)1
    70.44(a)1    		   II(6912605-6913293)3
    1741321  NM_001026719.31  NP_001021890.11 
    thale cress
    (Arabidopsis thaliana)    		 eudicotyledons AT1G019401 peptidyl-prolyl cis-trans isomerase-like 3 65.62(n)
    67.3(a)    		   839309  NM_100074.3  NP_171696.2 
    rice
    (Oryza sativa)    		 Liliopsida Os06g01305001 hypothetical protein 61.43(n)
    69.81(a)    		   4340003  NM_001063225.1  NP_001056690.1 
    E. coli
    (Escherichia coli)    		 Gamma proteobacteria ppiB6
    ppiA6
    		 peptidyl-prolyl cis-trans isomerase B (rotamase B)...
    peptidyl-prolyl cis-trans isomerase A (rotamase A)...
    		 24(a)
    20(a)
    		 possible ortholog
    possible ortholog
    		 Chromosome(553166-553660)
    Chromosome(3489747-3490319)


    ENSEMBL Gene Tree for PPIL3 (if available)
    TreeFam Gene Tree for PPIL3 (if available) 

    Paralogs
    for PPIL3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for PPIL3 gene
    CWC272  PPIL42  PPWD12  PPIH2  PPIB2  PPIC2  PPIL12  PPIL22  
    18/23 SIMAP similar genes for PPIL3 using alignment to 7 protein entries:     PPIL3_HUMAN (see all proteins) (see all similar genes):
    AURA2    PPIL2    NF2    PPIL4    PPWD1    PPIL1
    RANBP2    PPIA    CWC27    LOC402252    PPIF    PPIB
    PPIG    PPID    PPIE    PPIC    PPIL6    PPIH

    PPIL3 for paralogs           About GeneDecksing



    Genomic Variants
    for PPIL3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/281 NCBI SNPs in PPIL3 are shown (see all 281)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 2 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1144805161,2
    		F--201735251(+) AAACCC/TCGTCT 2 -- ds50011Minor allele frequency- T:0.02WA 118
    rs1443297921,2
    		--201735378(+) TGACCC/TGCTGC 2 -- ds50010--------
    rs1487477511,2
    		--201735394(+) AGCCCA/GGGTAA 2 -- ds50010--------
    rs710223431,2
    		C--201735425(+) AAAAA-/ATCAGA 2 -- ds50012Minor allele frequency- A:0.25NA 4
    rs787531731,2
    		F--201735656(+) TTTACG/ATTTCA 2 -- ds50011Minor allele frequency- A:0.03WA 118
    rs1458436831,2
    		C--201735706(+) ATATT-/TTAA  
                TTAAT     		2 -- ut310--------
    rs1414535651,2
    		--201735863(+) GTTCAC/TATGTA 2 -- ut310--------
    rs1508251611,2
    		C--201736068(+) CCACAA/GTAAGT 2 -- ut311Minor allele frequency- G:0.00EU 1321
    rs118921191,2
    		C,F,H--201736112(+) GTCTAT/CCATAG 2 -- ut3127Minor allele frequency- C:0.19NA NS EA WA CSA EU 3956
    rs75623911,2
    		C,F,A,H--201736166(+) TGTACA/CTCATT 4 E D mis125Minor allele frequency- C:0.24NA NS EA WA CSA EU 9068

    HapMap Linkage Disequilibrium report for PPIL3 (201735630 - 201754026 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for PPIL3: --

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    Disorders / Diseases
    for PPIL3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    PPIL3 for disorders           About GeneDecksing

    3 diseases for PPIL3:    About MalaCards
    tuberculosis    malaria    mycobacterium tuberculosis

    Human Genome Epidemiology (HuGE) Navigator: PPIL3 (1 document)

    Export disorders for PPIL3 gene to outside databases

    Publications
    for PPIL3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for PPIL3 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with PPIL3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of a novel peptidylprolyl isomerase (cyclophilin)-like gene (PPIL3) from human fetal brain. (PubMed id 11435694)1, 2, 3, 9 Zhou Z....Mao Y. (2001)
    2. Structure of recombinant human cyclophilin J, a novel member of the cyclophilin family. (PubMed id 15735342)1, 2 Huang L.-L.... Xia Z.-X. (2005)
    3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W....Wilson R.K. (2005)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis. (PubMed id 11991638)1, 2 Jurica M.S.... Moore M.J. (2002)
    7. Interaction with Ppil3 leads to the cytoplasmic localization of Apoptin in tumor cells. (PubMed id 18474220)1, 9 Huo D.H....Yang J. (2008)
    8. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. (PubMed id 22797925)1 Aichem A....Groettrup M. (2012)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)

    External Searches for PPIL3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
    		PubMed
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing PPIL3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 53938 HGNC: 9262 AceView: PPIL3 Ensembl:ENSG00000240344 euGenes: HUgn53938
    ECgene: PPIL3 H-InvDB: PPIL3

    Other Databases showing PPIL3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing PPIL3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for PPIL3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for PPIL3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for PPIL3 gene:
    Search GeneIP for patents involving PPIL3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
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    About This Section

     
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