PPIL2 Gene
protein-coding GIFtS: 61
GCID: GC22P022006
|
|
peptidylprolyl isomerase (cyclophilin)-like 2
| |
Aliases
for PPIL2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Peptidylprolyl Isomerase (Cyclophilin)-Like 21 2 | | CYP602 5 | | CYC41 2 | | Cyclophilin, 60kDa2 | | Cyp-601 2 | | Cyclophilin-603 | | UBOX71 2 | | HCyP-601 | | Cyclophilin-Like Protein Cyp-602 3 | | Peptidyl-Prolyl Cis-Trans Isomerase-Like 22 | | Rotamase PPIL22 3 | | Peptidylprolyl Cis-Trans Isomerase2 | | PPIase2 3 | | U-Box Domain Containing 72 | | EC 5.2.1.83 8 | | Cyclophilin-603 |
Export aliases for PPIL2 gene to outside databasesPrevious GC identifers: GC22P018719 GC22P020344 GC22P004978 |
Summaries
for PPIL2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for PPIL2:
This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conservedubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, andinfection of HIV-1 virions. This protein interacts with the proteinase inhibitor eglin c and is localized in thenucleus. Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq,Jul 2008)
UniProtKB/Swiss-Prot: PPIL2_HUMAN, Q13356Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidicpeptide bonds in oligopeptides
Gene Wiki entry for PPIL2
|
Genomic Views
for PPIL2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000022.10 NC_018933.1 NT_011520.12
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the PPIL2 gene promoter:
SRF NF-1/L NF-1 AML1a SRF (504 AA) HNF-4alpha2 HNF-4alpha1 E47 PPAR-alpha Hand1
Other transcription factors
Search SABiosciences Chromatin IP Primers for PPIL2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PPIL2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 22q11.21 Ensembl cytogenetic band: 22q11.21 HGNC cytogenetic band: 22q11.21PPIL2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 22 GeneLoc Exon Structure GeneLoc location for GC22P022006: view genomic region
(about GC identifiers)
Start:
|
22,006,559 bp from pter |
End:
|
22,052,565 bp from pter |
Size:
|
46,007 bases |
Orientation:
|
plus strand |
|
Proteins
for PPIL2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: PPIL2_HUMAN, Q13356 (See
protein sequence)Recommended Name: Peptidyl-prolyl cis-trans isomerase-like 2 Size: 520 amino acids; 58823 Da
Subcellular location: Nucleus
1 PDB 3D structure from  and Proteopedia  for PPIL2:1ZKC (3D)
Secondary accessions: Q13357 Q8TAH2 Q9BWR8Alternative splicing: 2 isoforms: Q13356-1 Q13356-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for PPIL2: NX_Q13356
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q13356
4/6 DME Specific Peptides for PPIL2 (Q13356) (see all 6)
PPIL2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_055152.1 NP_680480.1 NP_680481.1
ENSEMBL proteins: ENSP00000334553 ENSP00000381812 ENSP00000395181 ENSP00000406745 ENSP00000384299 ENSP00000405214 ENSP00000390427 ENSP00000396228 ENSP00000445312 Reactome Protein details: Q13356
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
PPIL2 for ontologies About GeneDecksing
PPIL2 Antibody Products:
Assay Products for PPIL2: |
Protein
Domains /
Families
for PPIL2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
PPIL2 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q13356ProtoNet protein and cluster: Q13356 2 Blocks protein families: IPB002130 Peptidyl-prolyl cis-trans isomerase IPB003613 Zn-finger
UniProtKB/Swiss-Prot: PPIL2_HUMAN, Q13356Similarity: Belongs to the cyclophilin-type PPIase family. PPIL2 subfamilySimilarity: Contains 1 PPIase cyclophilin-type domainSimilarity: Contains 1 U-box domain |
Function
for PPIL2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: PPIL2_HUMAN, Q13356Function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidicpeptide bonds in oligopeptidesCatalytic activity: Peptidylproline (omega=180) = peptidylproline (omega=0) Genatlas biochemistry entry for PPIL2:peptidylprolyl isomerase (cyclophilin)-like 2
Enzyme Number (IUBMB): EC 5.2.1.81 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PPIL2 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PPIL2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): PPIL2 (NM_148176) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PPIL2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PPIL2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPIL2 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
PPIL2 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for PPIL2:
|
Pathways & Interactions
for PPIL2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Basigin interactions | | | 2 | Cell surface interactions at the vascular wall | | | 3 | Platelet activation, signaling and aggregation | | | 4 | Antigen processing: Ubiquitination & Proteasome degradation | |
Pathway sources
See GeneCards unified pathways
Show all pathways
3 
Reactome Pathways for PPIL2
1 
Kegg Pathway (Kegg details for PPIL2):
PPIL2 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for PPIL2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
5/10 Interacting proteins for PPIL2 (Q133562, 3 ENSP000003904274) via UniProtKB, MINT, STRING, and/or I2D (see all 10)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table
PPIL2 for ontologies About GeneDecksing
|
Drugs & Compounds
for PPIL2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for PPIL2
Search CenterWatch for drugs/clinical trials and news about PPIL2
|
Transcripts
for PPIL2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for PPIL2 gene (3 alternative transcripts): NM_014337.3 NM_148175.2 NM_148176.2 Unigene Cluster for PPIL2: Peptidylprolyl isomerase (cyclophilin)-like 2 Hs.438587 [show with all ESTs]Unigene Representative Sequence: AK12725915 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000498589 ENST00000496819 ENST00000335025(uc002zvi.4 uc011aij.2)
ENST00000398831 ENST00000458567 ENST00000417788(uc002zvg.4 uc002zvk.4)
ENST00000484439 ENST00000406385 ENST00000498109 ENST00000485930 ENST00000446951
ENST00000462188 ENST00000412327(uc002zvh.4) ENST00000456792 ENST00000492445(uc010gtj.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PPIL2 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PPIL2 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): PPIL2 (NM_148176) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for PPIL2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PPIL2 |
Additional cDNA sequence: AF320072.1 AK097249.1 AK127259.1 AK289545.1 AK299206.1 BC000022.2 BC028385.2 CR456548.1 U37219.1 U37220.1 U37221.1 23 DOTS entries: DT.100660517 DT.100724398 DT.100031055 DT.100660513 DT.100660518 DT.120645714 DT.417942 DT.100852344 DT.100851485 DT.206198 DT.95096962 DT.100031054 DT.100848219 DT.99979971 DT.95079827 DT.95332725 DT.100660511 DT.100660514 DT.100808077 DT.120645747 DT.120645750 DT.91805490 DT.120645726 24/349 AceView cDNA sequences (see all 349): BM454952 NM_014337 AI223991 BM799027 AA678045 BX395099 AI962245 CB960364 AI139367 AA324876 CR605739 BM476342 CN483359 BQ679203 BU183351 BU162398 AW593722 AA995169 BC000022 AU129995 BX500302 CR456548 BQ052061 BU685062
GeneLoc Exon Structure
5/10 Alternative Splicing Database (ASD) splice patterns (SP) for PPIL2 (see all 10) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3 | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | ^ | 17a | · | 17b | · | 17c | ^ | 18 | ^ | 19a | · |
|---|
|
| SP1: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 19b | · | 19c | ^ | 20 | ^ | 21a | · | 21b | · | 21c | · | 21d | · | 21e | ^ | 22a | · | 22b | · | 22c |
|---|
|
| SP1: | | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | - | | | | - | | | | | | | | | | | | | | | | |
| SP3: | | | - | | | | - | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for PPIL2
|
Expression
for PPIL2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| PPIL2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGTGACCGTC
About this image
See PPIL2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for PPIL2
SOURCE GeneReport for Unigene cluster: Hs.438587
UniProtKB/Swiss-Prot: PPIL2_HUMAN, Q13356Tissue specificity: Highest expression in thymus, pancreas and testis. Also detected in heart, placenta, lung, liver,skeletal muscle, kidney, spleen, prostate, ovary, small intestine and colon. Poorly detected in brain and leukocytes.Strong protein expression in lymph node (cortical, paracortical and medullar regions), thyroid (follicular epithelialcells), testis (developing spermatozoa), stomach (cells lining the gastric pit), pancreas, kidney (proximal anddistal-tubule cells and collecting duct cells but not in glomeruli), endometrium and colon (goblet cells). Moderateprotein expression in spleen, prostate (epithelium and squamous cell carcinomas), placenta and adrenal gland. Weakprotein expression in liver, heart, breast, ovary, and lung. No protein expression in brain and bladder. High proteinexpression in most lymphomas and melanomas
SABiosciences Custom PCR Arrays for PPIL2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PPIL2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PPIL2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PPIL2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PPIL2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPIL2 |
Orthologs
for PPIL2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for PPIL2 gene from 9/34 species (see all 34) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
PPIL21 |
peptidylprolyl isomerase (cyclophilin)-like 2 |
74.9(n)
83.4(a) |
|
416775 NM_001030653.1 NP_001025824.1 |
lizard
(Anolis carolinensis) |
Reptilia |
PPIL26 |
-- |
79(a) |
1 ↔ 1 |
GL343282.1(1354017-1411761) |
African clawed frog
(Xenopus laevis) |
Amphibia |
MGC530462 |
similar to peptidylprolyl isomerase (cyclophilin)-like more |
72.45(n) |
|
BC044993.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc566162 |
similar to peptidylprolyl isomerase (cyclophilin)-like more |
78.05(n) |
|
393966 BC049506.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG77471 , 3 |
cyclophilin-type peptidy-prolyl cis-trans
isomerase3
CG77471 |
53(a)
(best of 2)3
59.52(n)1
54.97(a)1 |
|
53A53
368201 NM_137269.31 NP_611113.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
cyp-103
cyn-41 |
Cyclophilin3
Protein CYN-41 |
56(a)
(best of 2)3
53.23(n)1
50.49(a)1 |
|
II(6912605-6913293)3
1746741 NM_063936.51 NP_496337.11 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
PUB491 |
Peptidyl-prolyl cis-trans isomerase-like 2 |
52.69(n)
49.51(a) |
|
836889 NM_126153.3 NP_201554.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.269472 |
Oryza sativa (japonica cultivar-group) cDNA cloneJ more |
72.28(n) |
|
AK102337.1 |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
ppiB6ppiA6 |
peptidyl-prolyl cis-trans isomerase B (rotamase B)...peptidyl-prolyl cis-trans isomerase A (rotamase A)... |
33(a)26(a) |
possible orthologpossible ortholog |
Chromosome(553166-553660) Chromosome(3489747-3490319) |
ENSEMBL Gene Tree for PPIL2 (if available)
TreeFam Gene Tree for PPIL2 (if available) |
Paralogs
for PPIL2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for PPIL2 gene
- CWC272 PPIL42 PPWD12 PPIL32 PPIH2 PPIB2 PPIC2 PPIL12
18/19 SIMAP similar genes for PPIL2 using alignment to 5 protein entries: PPIL2_HUMAN (see all proteins)
(see all similar genes):PPIL1 PPIL3 PPIA PPWD1 PPIE PPIF
PPIH PPIB PPIC PPID CWC27 PPIAL4A
PPIAL4B PPIAL4C PPIAL4G PPIG DKFZp686G0426 NKTR
PPIL2 for paralogs About GeneDecksing
|
Genomic Variants
for PPIL2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 22 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for PPIL2 (22006559 - 22052565 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for PPIL2: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PPIL2 |
|
Disorders
/ Diseases
for PPIL2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
PPIL2 for disorders About GeneDecksing
OMIM gene information: 607588
OMIM disorders: --
8  diseases for PPIL2: About MalaCardssquamous cell carcinoma hermaphroditism tuberculosis thyroiditis
melanoma carcinoma prostatitis mycobacterium tuberculosis
Human Genome Epidemiology (HuGE) Navigator: PPIL2 (1 document)
Export disorders for PPIL2 gene to outside databases
|
Publications
for PPIL2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for PPIL2 gene, integrated from 9 sources (see all 21):
(articles sorted by number of sources associating them with PPIL2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (2004)
- The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 3 Dunham I....O'Brien K.P. (1999)
- Identification of a nuclear-specific cyclophilin which interacts with the proteinase inhibitor eglin c. (PubMed id 8660300)1, 2 Wang B.B.... Fisher J.M. (1996)
- Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Variation in RTN3 and PPIL2 genes does not influence platelet membrane beta-secretase activity or susceptibility to alzheimer's dise ase in the northern Irish population. (PubMed id 19669607)1 Carson R....Johnston J.A. (2009)
|
External Searches for PPIL2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing PPIL2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing PPIL2 gene
(According to HUGE)
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Specialized Databases showing PPIL2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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About This Section
| Patent Information for PPIL2 gene:
Search GeneIP for patents involving PPIL2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for PPIL2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for PPIL2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PPIL2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PPIL2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for PPIL2 | | OriGene 3'-UTR Clone for PPIL2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PPIL2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PPIL2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for PPIL2 | | OriGene Custom Protein Services for PPIL2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat PPIL2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PPIL2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PPIL2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PPIL2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat PPIL2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat PPIL2 |
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| | | | Search Tocris compounds for PPIL2 |
| |  |  |  |  | | | | | | Recombinant Protein for PPIL2 |
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 | | | PPIL2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPIL2 |
|  |  |  | | | | Search ThermoFisher Antibodies for PPIL2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PPIL2 |
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