Aliases for PPIL1 Gene
External Ids for PPIL1 Gene
Previous GeneCards Identifiers for PPIL1 Gene
This gene is a member of the cyclophilin family of peptidylprolyl isomerases (PPIases). The cyclophilins are a highly conserved, ubiquitous family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. Based on similarity to other PPIases, this protein could accelerate the folding of proteins and might catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. [provided by RefSeq, Jul 2008]
GeneCards Summary for PPIL1 Gene
PPIL1 (Peptidylprolyl Isomerase (Cyclophilin)-Like 1) is a Protein Coding gene. Diseases associated with PPIL1 include hiv-1. Among its related pathways are Spliceosome. GO annotations related to this gene include peptidyl-prolyl cis-trans isomerase activity. An important paralog of this gene is PPIB.
UniProtKB/Swiss-Prot for PPIL1 Gene
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing.