PPIB Gene

Aliases
for PPIB gene

Previous GC identifers: GC15M060234 GC15M057607 GC15M062026 GC15M062163 GC15M062235 GC15M041272

Summaries
for PPIB gene

Genomic Views
for PPIB gene

RefSeq DNA sequence:

NC_000015.9  NC_018926.1  NT_010194.17  

SwitchGear Promoter luciferase reporter plasmid: PPIB promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat PPIB

PPIB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15M064448:  view genomic region     (about GC identifiers)

Proteins
for PPIB gene

3 PDB 3D structures from and Proteopedia for PPIB:

1CYN (3D)        3ICH (3D)        3ICI (3D)    

Explore the universe of human proteins at neXtProt for PPIB: NX_P23284

Post-translational modifications:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	OriGene Purified Protein: PPIB OriGene Protein Over-expression Lysate: PPIB OriGene Custom Protein Services for PPIB
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	Novus Biologicals PPIB Proteins Novus Biologicals PPIB Lysate
	Sino Biological Recombinant Protein for PPIB
	ProSpec Recombinant Protein for PPIB
	Uscn Proteins for PPIB

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

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	R&D Systems Antibodies for PPIB (Cyclophilin B)
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	Uscn Antibodies for PPIB
	ThermoFisher Antibody for PPIB

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	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
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	GenScript Custom Assay Services for PPIB
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for PPIB

Protein Domains /
Families
for PPIB gene

ProtoNet protein and cluster: P23284

Function
for PPIB gene

miRNA Products:		miRTarBase miRNAs that target PPIB: hsa-mir-1 (MIRT001347)
		OriGene 3'-UTR Clone: PPIB Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat PPIB
		5 QIAGEN miScript miRNA Assays for microRNAs that regulate PPIB:
		hsa-miR-206 hsa-miR-520d-5p hsa-miR-524-5p hsa-miR-613 hsa-miR-1
		SwitchGear 3'UTR luciferase reporter plasmid: PPIB 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for PPIB (see all 7) OriGene shRNA RFP: PPIB OriGene siRNA: PPIB
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat PPIB

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for PPIB

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for PPIB (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for PPIB OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: PPIB (NM_000942)
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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat PPIB

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for PPIB
		Search LifeMap BioReagents cell lines for PPIB

In Situ Assay Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for PPIB

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

(inferred from 3 alleles) (MGI details for Ppib)

Pathways & Interactions
for PPIB gene

	Super-pathway	contained gene-specific pathways
1	Collagen formation	Collagen formation 1.00 Extracellular matrix organization 0.54 Collagen biosynthesis and modifying enzymes 0.74
2	BAFF in B-Cell Signaling	Apoptosis and survival_APRIL and BAFF signaling 0.39 Apoptosis and survival APRIL and BAFF signaling 0.39
3	Syndecan-1-mediated signaling events	Syndecan-1-mediated signaling events 1.00
4	Development_Prolactin receptor signaling	Prolactin Signaling Pathway 0.39

1 EMD Millipore Pathway for PPIB

Apoptosis and survival APRIL and BAFF signaling

1 GeneGo (Thomson Reuters) Pathway for PPIB

Apoptosis and survival APRIL and BAFF signaling

2 BioSystems Pathways for PPIB

	Prolactin Signaling Pathway
	Syndecan-1-mediated signaling events

3        Reactome Pathways for PPIB

	Extracellular matrix organization
	Collagen biosynthesis and modifying enzymes
	Collagen formation

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

Drugs & Compounds
for PPIB gene

Transcripts
for PPIB gene

Expression
for PPIB gene

PPIB expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GACTCACTTT

10 LifeMap In Vivo Development Anatomical Compartments/Cells
	Tissue Anatomical Compartment Cell			Category (developmental path)
	BoneEndochondral Facial Bones			Bone
	BoneRostral Endochondral Facial Bones			Bone
	BoneRostral Skull Membranous Bones			Bone
	BoneThoracic Rib			Bone
	CartilageCaudal Synchondroses			Cartilage
	CartilageChondrocranium			Cartilage
	CartilageRostral Chondrocranium			Cartilage
	CartilageRostral Synchondroses			Cartilage
	CartilageSynchondroses			Cartilage
	Head MesenchymeHead Mesenchyme			Head Mesenchyme
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for PPIB Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat PPIB
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In Situ Assay Products:

Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for PPIB

Orthologs
for PPIB gene

Paralogs
for PPIB gene

Paralogs for PPIB gene

CWC27²  PPIL4²  PPWD1²  PPIL3²  PPIH²  PPIC²  PPIL1²  PPIL2²  

18/22 SIMAP similar genes for PPIB using alignment to 1 protein entry:     PPIB_HUMAN(see all similar genes):

PPIC    PPIA    PPIE    PPIF    PPIH    LOC402252

RANBP2    PPIL1    PPID    PPIAL4A    PPIAL4B    PPIAL4C

PPIAL4G    PPIG    NKTR    PPWD1    PPIL3    PPIL6

PPIB for paralogs           About GeneDecksing

Genomic Variants
for PPIB gene

10/203 NCBI SNPs in PPIB are shown (see all 203)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 15 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs1214345591,2	C	pathogenic	64449001(-)	GCTCCC/TAGTTC	3	Q *	stg1 ut31		0	--	--	--	--
rs1378538641,2	C	pathogenic	64455160(-)	CAACAG/TGAAGG	2	R M	mis1		0	--	--	--	--
rs287201931,2	C	untested	64448960(-)	GATGGC/GAAGCA	3	G	syn1 ut31		5		NS	188
rs23072471,2	C,F,H,	untested	64452322(-)	TTCACC/TAGGGG	2	T	syn1 ese3		12		NA NS EU	6725
rs115585951,2	C,F,H	untested	64454311(-)	GCCGGG/TTGATC	2	V L	mis1 ese3		9		NS EA NA	762
rs49041,2	C,F,H,	untested	64455123(-)	GGGTCC/AGTCTT	2	/S	syn1 ese3		18		MN EA NS WA NA EU	7035
rs1818487441,2		--	64447594(+)	GTCAGC/GTGGGT	2	--	ds5001 ut31		0	--	--	--	--
rs38967871,2	H	--	64447742(+)	ATTTAG/AAGGTA	2	--	ds5001 ut31		5		MN NS EA	562
rs1864578931,2		--	64447773(+)	ACATCA/CCTTAA	2	--	ut31 ds5001		0	--	--	--	--
rs38589111,2	C,H	--	64447783(+)	ACATAG/AACTGG	2	--	ds5001 ut31		5		MN NS EA	602

HapMap Linkage Disequilibrium report for PPIB (64448011 - 64455404 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for PPIB: --
Human Gene Mutation Database (HGMD): PPIB

Locus Specific Mutation Databases (LSDB): PPIB

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing PPIB

DNA2.0 Custom Variant and Variant Library Synthesis for PPIB

Disorders / Diseases
for PPIB gene

Publications
for PPIB gene

PubMed articles for PPIB gene, integrated from 9 sources (see all 110) (see top 10): (articles sorted by number of sources associating them with PPIB)

Utopia: connect your pdf to the dynamic world of online information

1. Human cyclophilin B: a second cyclophilin gene encodes a peptidyl- prolyl isomerase with a signal sequence. (PubMed id 2000394)^{1, 2, 3, 9} Price E.R....Walsh C.T. (1991)
2. Lack of cyclophilin B in osteogenesis imperfecta with normal collagen folding. (PubMed id 20089953)^{1, 2, 3, 9} Barnes A.M....Marini J.C. (2010)
3. PPIB mutations cause severe osteogenesis imperfecta. (PubMed id 19781681)^{1, 2, 9} van Dijk F.S.... Pals G. (2009)
4. A novel secreted cyclophilin-like protein (SCYLP). (PubMed id 2040592)^{1, 2, 9} Spik G.... Movva N.R. (1991)
5. Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes. (PubMed id 17081065)^{1, 2} Chi A....Hunt D.F. (2006)
6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
7. X-ray structure of a cyclophilin B/cyclosporin complex: comparison with cyclophilin A and delineation of its calcineurin-binding domain. (PubMed id 8197205)^{1, 2} Mikol V.... Walkinshaw M.D. (1994)
8. S-cyclophilin is retained intracellularly via a unique COOH-terminal sequence and colocalizes with the calcium storage protein calreticulin. (PubMed id 1530944)^{1, 2} Arber S.... Caroni P. (1992)
9. Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. (PubMed id 1286667)^{1, 2} Rasmussen H.H....Vandekerckhove J. (1992)
10. An endoplasmic reticulum-specific cyclophilin. (PubMed id 1710767)^{1, 2} Hasel K.W.... Sutcliffe J.G. (1991)
11. Distribution of cyclophilin B-binding sites in the subsets of human peripheral blood lymphocytes. (PubMed id 9378502)^{1, 9} Denys A....Spik G. (1997)
12. The human TRPV6 channel protein is associated with cyclophilin B in human placenta. (PubMed id 18445599)^{1, 9} Stumpf T....Fecher-Trost C. (2008)
13. Expression of cyclophilin B is associated with malignant progression and regulation of genes implicated in the pathogenesis of breast cancer. (PubMed id 19056847)^{1, 9} Fang F....Clevenger C.V. (2009)
14. Receptor type I and type II binding regions and the peptidyl-prolyl isomerase site of cyclophilin B are required for enhancement of T-lymphocyte adhesion to fibronectin. (PubMed id 11955071)^{1, 9} Carpentier M....Spik G. (2002)
15. Selective assay for CyPA and CyPB in human blood using highly specific anti-peptide antibodies. (PubMed id 7829860)^{1, 9} Allain F....Spik G. (1995)
16. Synthesis of heparan sulfate with cyclophilin B-bindi ng properties is determined by cell type-specific expression of sulfotransferas es. (PubMed id 19940140)^{1, 9} Deligny A....Allain F. (2010)
17. The heparin/heparan sulfate sequence that interacts with cyclophilin B contains a 3-O-sulfated N-unsubstituted glucosamine residue. (PubMed id 17588944)^{1, 9} Vanpouille C....Allain F. (2007)
18. Characterization of surface binding sites for cyclophilin B on a human tumor T-cell line. (PubMed id 8206968)^{1, 9} Allain F....Spik G. (1994)
19. Cyclophilin B induces integrin-mediated cell adhesion by a mechanism involving CD98-dependent activation of protein kinase C-delta and p44/42 mitogen-activated protein kinases. (PubMed id 18054915)^{1, 9} Melchior A....Allain F. (2008)
20. CD147 is a signaling receptor for cyclophilin B. (PubMed id 11688976)^{1, 9} Yurchenko V....Bukrinsky M. (2001)
21. The hydrophobic pocket of cyclophilin is the binding site for the human immunodeficiency virus type 1 Gag polyprotein. (PubMed id 9032343)^{1, 9} Braaten D....Luban J. (1997)
22. Spatiotemporal behavior of nuclear cyclophilin B indic ates a role in RNA transcription. (PubMed id 22426501)¹ Dieriks B. and Van Oostveldt P. (2012)
23. A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
24. Cyclophilin B attenuates the expression of TNF-a in li popolysaccharide-stimulated macrophages through the induction of B cell lymphoma -3. (PubMed id 22798670)¹ Marcant A....Allain F. (2012)
25. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)¹ Kristensen A.R....Foster L.J. (2012)
26. Comparing human pancreatic cell secretomes by in vitro aptamer selection identifies cyclophilin B as a candidate pancreatic cancer bio marker. (PubMed id 22484812)¹ Ray P....White R.R. (2012)
27. Host cell interactome of HIV-1 Rev includes RNA helica ses involved in multiple facets of virus production. (PubMed id 22174317)¹ Naji S....Gerace L. (2012)
28. Release of overexpressed CypB activates ERK signaling through CD147 binding for hepatoma cell resistance to oxidative stress. (PubMed id 22555451)¹ Kim K....Choe W. (2012)
29. A major prolactin-binding complex on human milk fat gl obule membranes contains cyclophilins A and B: the complex is not the prolactin receptor. (PubMed id 22205628)¹ Lorenson M.Y....Walker A.M. (2012)
30. Involvement of cyclophilin B in the replication of Ja panese encephalitis virus. (PubMed id 21281954)¹ Kambara H....Matsuura Y. (2011)
31. Initial characterization of the human central proteome. (PubMed id 21269460)² Burkard T.R.... Colinge J. (2011)
32. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)¹ Wagner S.A....Choudhary C. (2011)
33. Synthesis, maturation, and trafficking of human Na+-d icarboxylate cotransporter NaDC1 requires the chaperone activity of cyclophilin B. (PubMed id 21257749)¹ Bergeron M.J....Hediger M.A. (2011)
34. Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyc losome substrate. (PubMed id 21628590)¹ Emanuele M.J....Elledge S.J. (2011)
35. Characterization of ubiquitination dependent dynamics in growth factor receptor signaling by quantitative proteomics. (PubMed id 21956701)¹ Akimov V....Blagoev B. (2011)
36. Dymeclin, the gene underlying Dyggve-Melchior-Clausen syndrome, encodes a protein integral to extracellular matrix and golgi organiz ation and is associated with protein secretion pathways critical in bone develo pment. (PubMed id 21280149)² Denais C....Machado R.D. (2011)
37. Mutations in PPIB (cyclophilin B) delay type I procol lagen chain association and result in perinatal lethal to moderate osteogenesis imperfecta phenotypes. (PubMed id 21282188)¹ Pyott S.M....Byers P.H. (2011)
38. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
39. An important role for CDK2 in G1 to S checkpoint activation and DNA damage response in human embryonic stem cells. (PubMed id 21319273)¹ Neganova I....Lako M. (2011)
40. Cyclosporin A associated helicase-like protein facili tates the association of hepatitis C virus RNA polymerase with its cellular cyc lophilin B. (PubMed id 21559518)¹ Morohashi K....Sugawara F. (2011)
41. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
42. Role of cyclophilin B in tumorigenesis and cisplatin resistance in hepatocellular carcinoma in humans. (PubMed id 21748762)¹ Kim Y....Kim S.S. (2011)
43. Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)¹ Hutchins J.R....Peters J.M. (2010)
44. Cyclophilin B as a co-regulator of prolactin-induced gene expression and function in breast cancer cells. (PubMed id 20237142)¹ Fang F....Clevenger C.V. (2010)
45. Cyclophilin B interacts with sodium-potassium ATPase and is required for pump activity in proximal tubule cells of the kidney. (PubMed id 21085665)¹ SuA+Ac G....Meseguer A. (2010)
46. Structural basis of cyclophilin B binding by the caln exin/calreticulin P-domain. (PubMed id 20801878)¹ Kozlov G....Gehring K. (2010)
47. Hepatitis C virus NS5A protein is a substrate for the peptidyl-prolyl cis/trans isomerase activity of cyclophilins A and B. (PubMed id 19297321)¹ Hanoulle X....Lippens G. (2009)
48. Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)¹ Sowa M.E....Harper J.W. (2009)
49. Cyclophilins contribute to Stat3 signaling and surviv al of multiple myeloma cells. (PubMed id 19503092)¹ Bauer K....Horn F. (2009)
50. Identification of host proteins required for HIV infe ction through a functional genomic screen. (PubMed id 18187620)¹ Brass A.L....Elledge S.J. (2008)
51. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PubMed id 17353931)¹ Ewing R.M.... Figeys D. (2007)
52. 14-3-3sigma controls mitotic translation to facilitate cytokinesis. (PubMed id 17361185)¹ Wilker E.W....Yaffe M.B. (2007)
53. A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)¹ Lim J.... Zoghbi H.Y. (2006)
54. How many drug targets are there? (PubMed id 17139284)⁷ Overington J.P....Hopkins A.L. (2006)
55. Analysis of the DNA sequence and duplication history of human chromosome 15. (PubMed id 16572171)² Zody M.C....Nusbaum C. (2006)
56. Drugs, their targets and the nature and number of dru g targets. (PubMed id 17016423)⁷ Imming P....Meyer A. (2006)
57. Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase. (PubMed id 15989969)¹ Watashi K....Shimotohno K. (2005)
58. Protein profiling of human pancreatic islets by two-dimensional gel electrophoresis and mass spectrometry. (PubMed id 15952740)¹ Ahmed M....Bergsten P. (2005)
59. Nucleolar proteome dynamics. (PubMed id 15635413)¹ Andersen J.S....Mann M. (2005)
60. A human protein-protein interaction network: a resource for annotating the proteome. (PubMed id 16169070)¹ Stelzl U.... Wanker E.E. (2005)
61. Role of cyclophilin B in activation of interferon regulatory factor-3. (PubMed id 15764595)¹ Obata Y....Matsuyama T. (2005)
62. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)² Ota T.... Sugano S. (2004)
63. Identification of FHOD1-binding proteins and mechanisms of FHOD1-regulated actin dynamics. (PubMed id 15095401)¹ Westendorf J.J. and Koka S. (2004)
64. Cyclophilin D, a component of the permeability transition-pore, is an apoptosis repressor. (PubMed id 14729611)¹ Schubert A. and Grimm S. (2004)
65. Nascent lipidated apolipoprotein B is transported to the Golgi as an incompletely folded intermediate as probed by its association with network of endoplasmic reticulum molecular chaperones, GRP94, ERp72, BiP, calreticulin, and cyclophilin B. (PubMed id 12397072)¹ Zhang J. and Herscovitz H. (2003)
66. Immunophilins and HIV-1 infection. (PubMed id 12181673)¹ Minder D....Gehring H. (2002)
67. TTD: Therapeutic Target Database. (PubMed id 11752352)⁷ Chen X....Chen Y.Z. (2002)
68. Interaction with glycosaminoglycans is required for cyclophilin B to trigger integrin-mediated adhesion of peripheral blood T lymphocytes to extracellular matrix. (PubMed id 11867726)¹ Allain F....Spik G. (2002)
69. A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins. (PubMed id 12475965)¹ Meunier L....Hendershot L.M. (2002)
70. The intranuclear prolactin/cyclophilin B complex as a transcriptional inducer. (PubMed id 11997457)¹ Rycyzyn M.A. and Clevenger C.V. (2002)
71. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
72. Role of cyclophilin B in prolactin signal transduction and nuclear retrotranslocation. (PubMed id 10935542)¹ Rycyzyn M.A....Clevenger C.V. (2000)
73. The Protein Data Bank. (PubMed id 10592235)⁷ Berman H.M....Bourne P.E. (2000)
74. Human cyclophilin has a significantly higher affinity for HIV-1 recombinant p55 than p24. (PubMed id 10096576)¹ Bristow R....Duncan J. (1999)
75. Maturation-induced conformational changes of HIV-1 capsid protein and identification of two high affinity sites for cyclophilins in the C-terminal domain. (PubMed id 10026140)¹ Endrich M.M....Gehring H. (1999)
76. The V3 loop of human immunodeficiency virus type-1 envelope protein is a high-affinity ligand for immunophilins present in human blood. (PubMed id 9546659)¹ Endrich M.M. and Gehring H. (1998)
77. Native recombinant cyclophilins A, B, and C degrade DNA independently of peptidylprolyl cis-trans-isomerase activity. Potential roles of cyclophilins in apoptosis. (PubMed id 9045699)¹ Montague J.W....Cidlowski J.A. (1997)
78. Construction of a human full-length cDNA bank. (PubMed id 7821789)¹ Kato S....Aoki T. (1994)
79. Calcium signalling in T cells stimulated by a cyclophilin B-binding protein. (PubMed id 7522304)¹ Bram R.J. and Crabtree G.R. (1994)
80. Cyclophilin B trafficking through the secretory pathway is altered by binding of cyclosporin A. (PubMed id 7909608)¹ Price E.R....McKeon F.D. (1994)
81. Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B. (PubMed id 8513493)¹ Luban J.... Goff S.P. (1993)
82. Somatic cell mapping of the human cyclophilin B gene (PPIB) to chromosome 15. (PubMed id 1505219)¹ Peddada L.B....Deans R.J. (1992)
83. Evidence that human milk isolated cyclophilin B corresponds to a truncated form. (PubMed id 8652625)⁹ Mariller C....Spik G. (1996)
84. Octasaccharide is the minimal length unit required for efficient binding of cyclophilin B to heparin and cell surface heparan sulphate. (PubMed id 15109301)⁹ Vanpouille C....Allain F. (2004)
85. Receptor-mediated transcytosis of cyclophilin B through the blood-brain barrier. (PubMed id 10386979)⁹ Carpentier M....Spik G. (1999)
86. Enhancing the effect of secreted cyclophilin B on immunosuppressive activity of cyclosporine. (PubMed id 9583869)⁹ Denys A....Spik G. (1998)
87. Cyclophilin B binding to platelets supports calcium-dependent adhesion to collagen. (PubMed id 10419889)⁹ Allain F....Spik G. (1999)
88. Hsp47 and cyclophilin B traverse the endoplasmic reticulum with procollagen into pre-Golgi intermediate vesicles. A role for Hsp47 and cyclophilin B in the export of procollagen from the endoplasmic reticulum. (PubMed id 7629154)⁹ Smith T....Sauk J.J. (1995)
89. Severe osteogenesis imperfecta in cyclophilin B-defic ient mice. (PubMed id 19997487)⁹ Choi J.W....Bram R.J. (2009)
90. Involvement of the N-terminal part of cyclophilin B in the interaction with specific Jurkat T-cell binding sites. (PubMed id 8713087)⁹ Mariller C....Spik G. (1996)
91. Overexpressed cyclophilin B suppresses apoptosis associated with ROS and Ca2+ homeostasis after ER stress. (PubMed id 18946027)⁹ Kim J....Kim S.S. (2008)
92. Target cell cyclophilins facilitate human papillomavi rus type 16 infection. (PubMed id 19629175)⁹ Bienkowska-Haba M....Sapp M. (2009)
93. Cyclophilin B mediates cyclosporin A incorporation in human blood T-lymphocytes through the specific binding of complexed drug to the cell surface. (PubMed id 8713086)⁹ Allain F....Spik G. (1996)
94. Basic fibroblast growth factor induces 3T3 fibroblasts to synthesize and secrete a cyclophilin-like protein and beta 2-microglobulin. (PubMed id 1932134)⁹ Davis T.R....Nilsen-Hamilton M. (1991)
95. Recessive osteogenesis imperfecta caused by LEPRE1 mutations: clinical documentation and identification of the splice form responsible for prolyl 3-hydroxylation. (PubMed id 19088120)⁹ Willaert A....De Paepe A. (2009)
96. Syndecan-1/CD147 association is essential for cyclophilin B-induced activation of p44/42 mitogen-activated protein kinases and promotion of cell adhesion and chemotaxis. (PubMed id 17267519)⁹ Pakula R....Allain F. (2007)
97. Identification of homologs for thioredoxin, peptidyl prolyl cis-trans isomerase, and glycerophosphodiester phosphodiesterase in outer membrane fractions from Treponema pallidum, the syphilis spirochete. (PubMed id 9317025)⁹ Shevchenko D.V....Radolf J.D. (1997)
98. Prolyl 3-hydroxylase 1 and CRTAP are mutually stabili zing in the endoplasmic reticulum collagen prolyl 3-hydroxylation complex. (PubMed id 19846465)⁹ Chang W....Marini J.C. (2010)
99. Commonly used reference genes are actively regulated in in vitro stimulated lymphocytes. (PubMed id 17257226)⁹ Roge R....Carstens J. (2007)
100. High level expression and characterization of the cyclophilin B gene from the anaerobic fungus Orpinomyces sp. strain PC-2. (PubMed id 17018017)⁹ Chen H....Cerniglia C.E. (2006)
101. Isolation of a new cyclophilin-like protein from chickpeas with mitogenic, antifungal and anti-HIV-1 reverse transcriptase activities. (PubMed id 11848297)⁹ Ye X.Y. and Ng T.B. (2002)
102. Isolation of unguilin, a cyclophilin-like protein with anti-mitogenic, antiviral, and antifungal activities, from black-eyed pea. (PubMed id 11732686)⁹ Ye X.Y. and Ng T.B. (2001)
103. Delineation of the calcineurin-interacting region of cyclophilin B. (PubMed id 11206060)⁹ Carpentier M....Spik G. (2000)

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