PPIAL4G Gene

Aliases
for PPIAL4G gene

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Previous GC identifer: GC01M142557

Summaries
for PPIAL4G gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Genomic Views
for PPIAL4G gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:

NC_000001.10  NC_018912.2  NT_004487.20  

Browse SwitchGear Promoter luciferase reporter plasmids

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat PPIAL4G

PPIAL4G Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M143767:  view genomic region     (about GC identifiers)

Proteins
for PPIAL4G gene

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, antibodies-online, and/or GeneTex,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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Explore the universe of human proteins at neXtProt for PPIAL4G: NX_A2BFH1

Explore proteomics data for PPIAL4G at MOPED

Post-translational modifications: 

PPIAL4G Human Recombinant Protein Products:

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	antibodies-online proteins for PPIAL4G (2 products)
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PPIAL4G Antibody Products:

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	antibodies-online antibodies for PPIAL4G (9 products)

PPIAL4G Assay Products:

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	antibodies-online kits for PPIAL4G (2 products)

Domains /
Families
for PPIAL4G gene

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GenesLikeMe)
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ProtoNet protein and cluster: A2BFH1

Find genes that share domains with PPIAL4G           About GenesLikeMe

Function
for PPIAL4G gene

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
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     Enzyme Number (IUBMB): EC 5.2.1.8¹

     Gene Ontology (GO): 1 molecular function term:    About this table

genOway: Develop your customized and physiologically relevant rodent model for PPIAL4G

miRNA Products:		miRTarBase miRNAs that target PPIAL4G: hsa-mir-324-5p (MIRT043026), hsa-mir-191-5p (MIRT045799), hsa-mir-320a (MIRT044567), hsa-mir-18a-3p (MIRT040949), hsa-mir-423-5p (MIRT038041)
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		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for PPIAL4G
		Predesigned siRNA for gene silencing in human, mouse, rat PPIAL4G

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for PPIAL4G

Clone Products:		OriGene clones in human, mouse for PPIAL4G (see all 5) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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		Browse Sino Biological Human cDNA Clones
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In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPIAL4G

Localization
for PPIAL4G gene

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
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Gene Ontology (GO): 1 cellular component term:    About this table

Pathways & Interactions
for PPIAL4G gene

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GenesLikeMe, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
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Gene Ontology (GO): 1 biological process term:    About this table

Drugs & Compounds
for PPIAL4G gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, Sets of similar genes according to GenesLikeMe)
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Transcripts
for PPIAL4G gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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Expression
for PPIAL4G gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GenesLikeMe, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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PPIAL4G expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for PPIAL4G
		Pre-validated RT2 qPCR Primer Assay in human, mouse / rat PPIAL4G
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In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for PPIAL4G

Orthologs
for PPIAL4G gene

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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Paralogs
for PPIAL4G gene

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68,Sets of similar genes according to GenesLikeMe)
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Paralogs for PPIAL4G gene

PPIAL4C^1 2  PPIAL4B^1 2  PPIAL4F  PPIAL4E  PPIAL4D^1 2  PPIE²  RANBP2²  RGPD6²  

PPIF²  PPIA²  PPIAL4A²  RGPD2²  RGPD4²  RGPD3²  RGPD1²  RGPD5²  

RGPD8²  

Selected SIMAP similar genes for PPIAL4G using alignment to 1 protein entry:     PAL4G_HUMAN(see all similar genes):

PPIAL4A    PPIAL4B    PPIAL4C    PPIAL4D    PPIA    LOC402252

PPIF    RANBP2    PPIE    PPIC    PPIB    PPID

PPIH    PPIL1    PPIL6    DKFZp686G0426    NKTR    CWC27

Find genes that share paralogs with PPIAL4G           About GenesLikeMe


2 Pseudogenes.org Pseudogenes for PPIAL4G
PGOHUM00000234654 PGOHUM00000235579

Genomic Variants
for PPIAL4G gene

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for PPIAL4G (see all 58)    About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs2006457591,2	C	--	143767235(+)	AAAGGA/GAACTG	1	--	ut31		0	--	--	--	--
rs2016066841,2	C	--	143767254(+)	GCACAA/GAGATT	1	--	ut31		0	--	--	--	--
rs2006373031,2	C,F	--	143767312(+)	CAGAAG/TGAATG	1	--	ut31		1		EU	179
rs2016484111,2	C	--	143767357(+)	CATTAG/CAATTG	2	/F /L	mis1		1		EU	1177
rs776416281,2	C,F	--	143767466(+)	CAAAGG/ACCACA	2	/A /V	mis1		2		NA EU	963
rs66045111,2	C,F,A	--	143767513(+)	ATGAAT/AAACTG	2	/L /F	mis1		2		NA	6
rs66045121,2	C,F,A	--	143767522(+)	TGGGAA/GCCATT	2	G	syn1		3		NA	8
rs24901831,2	C	--	143767547(+)	CATTTA/GCCATG	2	A V	mis1		0	--	--	--	--
rs66045141,2	C,F,A	--	143767628(+)	TGTCAC/TCGGTG	2	D G	mis1		1		EU	359
rs124077261,2	C,F,H	--	143767629(+)	GTCACC/TGGTGC	2	S G	mis1		4		NS NA EU	1607

HapMap Linkage Disequilibrium report for PPIAL4G (143767144 - 143767881 bp)

Structural Variations
     Database of Genomic Variants (DGV) 1 variation for PPIAL4G:    About this table    

Variant ID	Type	Subtype	PubMed ID
esv27827	CNV	Gain	19812545

Site Specific Mutation Identification with PCR Assays

Search QIAGEN SeqTarget long-range PCR primers for resequencing PPIAL4G

DNA2.0 Custom Variant and Variant Library Synthesis for PPIAL4G

Disorders / Diseases
for PPIAL4G gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB, Sets of similar genes according to GenesLikeMe)
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Publications
for PPIAL4G gene

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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1. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)² Gregory S.G.... Bentley D.R. (Nature 2006)
2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S.... Malek J. (Genome Res. 2004)
3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (Nat. Genet. 2004)
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

External Searches for PPIAL4G gene

Genome Databases showing PPIAL4G gene

Other Databases showing PPIAL4G gene

Specialized Databases showing PPIAL4G gene

Products
for PPIAL4G gene

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, GeneTex, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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